Glurenorm ga masu ciwon sukari - cikakke umarni da sake dubawa game da masu ciwon sukari

Ofayan wakilan babban rukuni na abubuwan da aka samo asali na sulfonylurea (PSM) shine Glurenorm na baka. Abunda yake aiki, glycidone, yana da tasirin hypoglycemic, an nuna shi ga nau'in ciwon sukari na 2. Duk da ƙaramar shahararsa, Glurenorm yana da tasiri daidai kamar yadda analogues na ƙungiyar sa. Kusancin ba a maganin da kodan ke cire shi, saboda haka ana amfani dashi da yawa a cikin cututtukan ƙwaƙwalwar koda tare da gazawar ci gaba na koda. Glurenorm ya fito ne daga sashen Girka na kamfanin sarrafa magunguna na kasar Beringer Ingelheim.

Manufa ta aiki

Glurenorm yana cikin ƙarni na 2 na PSM. Magungunan yana da duk halayen magungunan gargajiya na wannan rukunin mahaɗan hypoglycemic:

1. Babban aiki shine maganin cututtukan zuciya. Glycvidone, sashi mai aiki a cikin allunan na Glurenorm, ya daure wa masu karbar suttura na jiki da kuma karfafa kwayar insulin a ciki. Increaseara yawan haɗarin wannan hormone a cikin jini yana taimakawa wajen shawo kan juriya na insulin, kuma yana taimakawa kawar da sukari daga tasoshin jini.
2. Additionalarin ƙarin aiki shine extrapancreatic. Glurenorm yana haɓaka hankalin insulin, rage ƙaddamar da glucose a cikin jini daga hanta. Nau'in nau'in ciwon sukari na 2 ana nuna shi ta mahaukaci a cikin bayanan lafiyar jini. Glurenorm yana taimakawa wajen daidaita waɗannan alamomin, yana hana thrombosis.

Allunan suna aiki akan kashi na 2 na aikin insulin, don haka a karo na farko bayan cin sukari za'a iya karuwa. Dangane da umarnin, sakamakon maganin yana farawa ne bayan kimanin awa daya, ana lura da mafi girman sakamako, ko ganiya, bayan awa 2.5. Jimlar aikin ta kai awa 12.

Duk PSM na zamani, gami da Glurenorm, suna da mummunar rashi: suna taɓar da ƙwaƙwalwar insulin, ba tare da la'akari da matakin sukari ba a cikin tasoshin masu ciwon sukari, wato, yana aiki da hyperglycemia da sukari na al'ada. Idan ƙarancin glucose na jini zuwa ga jini fiye da yadda aka saba, ko kuma an kashe shi akan aikin tsoka, sai an fara magana da hypoglycemia. Dangane da sake dubawar masu ciwon sukari, haɗarinsa yana da girma musamman yayin ganiya da miyagun ƙwayoyi kuma tare da tsawan lokaci.

Pharmacokinetics na miyagun ƙwayoyi

Babban rukuni na marasa lafiya da ke dauke da ciwon sukari na 2 shine tsofaffi. An nuna su da raguwar ilimin halittar jiki a cikin aikin aikin yara na kodan. Idan ciwon sukari ya lalace, marasa lafiya suna cikin haɗarin cutar nephropathy, sannan gazawar koda. Yawancin abubuwan hypoglycemic suna dauke da kodan, idan sun kasance kasawa, tarin magunguna a cikin jiki ya fara, wanda ke haifar da mummunan cutar hypoglycemia.

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

Glurenorm yana ɗayan magunguna masu aminci ga kodan. Umarnin don amfani yana nuna cewa yana cikin hanzari kuma yana ɗaukar ƙwayar narkewa, sannan hancinsa ya rushe shi don aiki ko rauni mai ƙarfi metabolites. Mafi yawansu, kashi 95%, an kebe su da feces. Kodan yakai kashi 5% na metabolites kawai. Don kwatantawa, an saki 50% na glibenclamide (Maninil), 65% na glyclazide (Diabeton), 60% na glimepiride (Amaryl) an saki su tare da fitsari. Saboda wannan fasalin, ana ɗaukar Glurenorm a matsayin magani na zaɓi ga masu ciwon sukari na nau'in 2 tare da rage ƙwaƙwalwar koda.

Alamu don shigowa

Koyarwar ta ba da shawarar yin magani tare da Glurenorm kawai tare da ingantaccen nau'in ciwon sukari na 2, wanda ya hada da masu cutar sukari da kuma masu haƙuri na tsakiya.

Nazarin sun tabbatar da babban tasirin rage sukari na ƙwayar cutar Glyurenorm. Lokacin da aka tsara shi nan da nan bayan gano ciwon sukari a cikin adadin yau da kullun na har zuwa 120 MG a cikin masu ciwon sukari, matsakaiciyar raguwa a cikin glycated haemoglobin sama da makonni 12 shine 2.1%. A cikin rukunin da ke shan glycidone da rukunin analogue glibenclamide, kusan adadin waɗannan marasa lafiya sun sami diyyar mellitus diyya, wanda ke nuna kusan tasirin waɗannan kwayoyi.

Lokacin da Glurenorm ba zai iya sha ba

Umarnin amfani da shi ya haramta shan Glurenorm don kamuwa da cutar siga a cikin waɗannan lambobin:

1. Idan mai haƙuri bashi da ƙwayoyin beta. Dalilin na iya zama kamannin cututtukan fitsari ko nau'in 1 masu ciwon suga.
2. A cikin cututtukan hanta mai tsanani, hepatic porphyria, glycidone za a iya metabolized isasshe kuma tara a cikin jiki, wanda ke haifar da wucewar gaba.
3. Tare da hyperglycemia, ketoacidosis ya rage nauyi da rikice-rikice - precoma da coma.
4. Idan mai haƙuri yana da rashin ƙarfi ga glycvidone ko wasu PSM.
5. Tare da hypoglycemia, miyagun ƙwayoyi ba zasu iya bugu ba har sai an daidaita sukari.
6. A cikin mummunan yanayi (mummunan cututtuka, raunin da ya faru, tiyata), ana maye gurbin glurenorm na ɗan lokaci ta hanyar insulin far.
7. A lokacin daukar ciki da kuma lokacin hepatitis B, an haramta amfani da maganin sosai, tunda glycidone ya shiga jinin yaro kuma ya cutar da ci gabansa.

Rashin lafiyar mahaifa halayyar cututtukan thyroid na iya canza ayyukan insulin. Irin waɗannan marasa lafiya ana nuna su da kwayoyi waɗanda ba sa haifar da hypoglycemia - metformin, glyptins, acarbose.

Yin amfani da miyagun ƙwayoyi Glurenorm a cikin barasa yana da rauni tare da maye mai ƙarfi, rashin tsalle-tsalle a cikin ƙwayar cuta.

Dokokin shigar da kara

Akwai wadatar glurenorm a sashi na 30 MG kawai. Allunan suna da haɗari, saboda haka za'a iya rarrabawa don samun rabin kashi.

Ana shayar da magani ko dai nan da nan kafin cin abinci, ko a farkonsa. A wannan yanayin, a ƙarshen abinci ko kuma bayansa, matakin insulin zai karu da kusan 40%, wanda zai haifar da raguwar sukari. Decreasearin rage yawan insulin yayin amfani da Glyurenorm yana kusa da ilimin kimiya, sabili da haka, haɗarin hypoglycemia yana da ƙasa. Koyarwar ta bada shawarar farawa da rabin kwaya a karin kumallo. Sannan a hankali ana kara girman har sai an samu biyan diyya ga masu cutar siga. Tsarin tsakani tsakanin daidaitawa ya kamata ya zama aƙalla kwanaki 3.

Karka tsallake abinci bayan shan magani. Dole samfura su ƙunshi carbohydrates, zai fi dacewa da low glycemic index. Amfani da Glenrenorm baya soke abincin da aka tanada a baya da kuma motsa jiki. Tare da amfani da ƙwayar carbohydrates da ƙarancin aiki, ƙwayar ba zata iya ba da diyya ga masu ciwon sukari ba a cikin yawancin marasa lafiya.

Amincewa da Glyurenorm tare da nephropathy

Ba a buƙatar daidaita sikelin ƙwayar cuta don cutar koda. Tunda glycidone an fi raba shi ta hanyar kodan, masu ciwon sukari tare da nephropathy ba sa kara yawan haɗarin hypoglycemia, kamar yadda yake da sauran kwayoyi.

Bayanan gwaji sun nuna cewa sama da makonni 4 na amfani da miyagun ƙwayoyi, proteinuria yana raguwa tare da ingantaccen kula da ciwon sukari na mellitus, kuma farfadowa da fitsari ya inganta. Dangane da sake dubawa, Glurenorm an wajabta shi ko da bayan sauyawar koda.

Yi amfani da shi don cututtukan hanta

Koyarwar ta hana shan Glurenorm cikin gazawar hanta. Koyaya, akwai shaidar cewa glycidone metabolism a cikin cututtukan hanta galibi ana kiyaye shi, yayin da lalacewar aikin ba ya faruwa, kuma yawan tasirin sakamako baya ƙaruwa. Sabili da haka, nadin Glyurenorm ga irin waɗannan marasa lafiya yana yiwuwa bayan cikakken bincike.

Hada magani

A cikin umarnin don Glyurenorm, an yarda da karɓar maganin kawai tare da metformin. Dangane da sake dubawa, magunguna kuma yana da kyau tare da acarbose, Dhib-4 inhibitors, insulin. Don hana yawan zubar da ruwa, Glyrenorm an hana shi shan a lokaci guda kamar sauran PSM.

Side effects, yawan abin sama da ya kamata

Mitar abubuwan da ba a ke so ba yayin shan ƙwayar cutar Glurenorm:

A cikin maganganun da aka keɓe, akwai keta haddi na zubar da jini, cutar urticaria, raguwar matakin leukocytes da granulocytes a cikin jini.

Game da yawan abin sama da ya kamata, cutar hawan jini tayi yawa. Kawar da shi ta hanyar maganin ta baki ko na ciki. Bayan daidaituwa na sukari, zai iya fada akai-akai akai har sai an fitar da maganin daga jikin.

Hulɗa da ƙwayoyi

Sakamakon Glenrenorm na iya canzawa tare da magani na lokaci daya tare da wasu kwayoyi:

• maganin hana haihuwa, abubuwan motsa jiki na CNS, kwayoyin hodar iblis da kuma cututtukan thyroid, nicotinic acid, chlorpromazine sun raunana tasirin sa;
• wasu NSAIDs, maganin rigakafi, maganin rigakafi, maganin rigakafi, coumarins (acenocoumarol, warfarin), thiazide diuretics, beta-blockers, ethanol suna inganta tasirin maganin.

Umarni na musamman

Lokacin ɗaukar Glyurenorm, bin yarda da shawarwarin likita don al'ada na metabolism metabolism ana buƙatar. Gudanar da nauyin jikin, tsananin riko da abincin da aka tsara, duba aikin yau da kullun na aikin koda ya zama dole.

Game da sakamako masu illa, kuna buƙatar tuntuɓar likita da gaggawa don warware batun buƙatar canza magani.

A cikin ayyukan da ke buƙatar matuƙar maida hankali (tuki, aiki tare da kayan aiki, a tsayi, da dai sauransu), kuna buƙatar yin hankali sosai don kar ku ɓoye alamun farko na hypoglycemia. Rashin haɗarin sukari yana faɗuwa mafi girma a lokacin karuwar sashi.

Masu sauya farashin da Glurenorm

Farashin fakiti tare da allunan 60 na Glyurenorm kusan 450 rubles. Ba a haɗa da abu mai glycidon a cikin jerin magungunan mahimmanci ba, don haka ba zai yiwu a sami shi kyauta ba.

Cikakken analog tare da kayan aiki ɗaya a cikin Rasha ba a same su ba tukuna. Yanzu ana kan hanyar yin rijistar ga maganin Yuglin, wanda ya kirkiro da Pharmasynthesis. An riga an tabbatar da daidaituwar yanayin halitta na Yuglin da Glyurenorm, sabili da haka, nan da nan ana tsammanin ya bayyana akan siyarwa.

A cikin masu ciwon sukari tare da kodan lafiya, kowane PSM na iya maye gurbin Glurenorm. Suna tartsatsi, saboda haka yana da sauƙi a zaɓi magani mai araha. Kudin magani yana farawa daga 200 rubles.

A cikin gazawar koda, ana bada shawarar linagliptin. Wannan kayan aiki mai aiki yana cikin shirye-shiryen Trazhent da Gentadueto. Farashin allunan a kowane wata na jiyya daga 1600 rubles.

Nazarin masu ciwon sukari