Amisosyline Nycomed memba ne na ƙungiyar tricyclic antidepressant kungiyar. Magungunan ƙwaƙwalwa shine rukuni na ƙarancin farashi, wanda yake mahimmanci, saboda yawanci lokacin magani shine makonni da yawa ko ma watanni.
Sunan kasa da kasa mai zaman kansa
Amitriptyline.
Amisosyline Nycomed memba ne na ƙungiyar tricyclic antidepressant kungiyar.
ATX
N06AA09.
Saki siffofin da abun da ke ciki
Samfurin yana cikin nau'ikan allunan. Wannan shiri ne guda-daya, ya ƙunshi abu mai aiki 1 - amitriptyline. Allunan suna da harsashi, saboda abin da rage girman tasirin tasirin miyagun ƙwayoyi akan ƙwayoyin mucous na ƙwayar narkewa. Mayar da hankalin abu mai aiki: 10 ko 25 MG (a cikin kwamfutar hannu 1). Magungunan ƙwayar cuta yana ƙunshe da abubuwa da yawa marasa aiki waɗanda ake amfani da su don buƙatar daidaitattun magungunan da ake so:
- magnesium stearate;
- microcrystalline cellulose;
- silica;
- talc;
- lactose monohydrate.
- sitaci.
Amitriptyline an samar dashi a cikin nau'ikan allunan mai rufi, saboda wanda ya rage girman zafin tasirin magani a jikin mucous membranes na gastrointestinal tract.
Shellararren kariya samfurin ɗin shima yalwatace:
- macrogol;
- dimethicone;
- prolylene glycol;
- titanium dioxide;
- hypromellose;
- foda talcum.
Allunan suna dauke ne a cikin wata kwalba mai dauke da kwamfutoci guda 50.
Aikin magunguna
Thea'idar aikin antidepressants na tricyclic antidepressants ya dogara da hanawar kama monoamines, wanda norepinephrine, dopamine da serotonin suke wakilta. Wadannan abubuwan suna da alhakin motsawar farin ciki.
Magungunan, kamar sauran hanyoyin rukunin antioxidant na tricyclic, yana da gagarumin koma baya - adadi mai yawa na sakamako masu illa da ke faruwa yayin jiyya. Wannan ya faru ne saboda yanayin aiwatar da aikin da ba na zabi ba. A sakamakon haka, magungunan ba wai kawai yana shafan kamun kwayoyin bane kawai, amma yana hana sauran halayen ƙwayoyin cuta.
Amitriptyline lokaci guda yana aiwatar da ayyuka da yawa. Babban abincinta shine maganin antidepressant. Bugu da ƙari, miyagun ƙwayoyi suna ba da sakamako mai guba, anxiolytic, sakamako na hypnotic. Wannan yana nufin cewa yayin lura ba wai kawai yanayin hankalin mai haƙuri ya saba ba, har ma an dawo da bacci, damuwa ta ɓace.
Amitriptyline yana ba da sakamako mai narkewa, saboda wanda haƙuri ke mayar da bacci.
Sakamakon ikon hana sake haɗuwa da kwayoyin halitta na monoamines, an lura da karuwa a cikin taro a cikin ƙwaƙwalwar synaptic na tsarin juyayi na tsakiya. Bugu da ƙari, sashin aiki mai aiki na Amitriptyline Nycomed tubalan M1- da M2-muscarinic cholinergic masu karɓa, masu karɓa na histamine, kuma a lokaci guda masu karɓar alpha1-adrenergic. Ana lura da ingantacciyar tasirin magani tare da wannan maganin rashin damuwa saboda haɗin da ke gudana tsakanin masu samar da ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa waɗanda ke cikin abubuwan da ke cikin kwakwalwar kwakwalwa da yanayin tunanin mutum.
Wani fasalin na miyagun ƙwayoyi shine sakamako mai sauƙi. Ba'a samun sakamako mai kyau nan da nan, amma bayan maida hankali akan abu mai aiki a cikin jini yana isa zuwa matakin daidaitawa. Bugu da kari, lokacin da ya kai wani matakin (yana da bambanci gwargwadon yawan), ana nuna tasirin mai ba da rai wanda yake inganta rayuwa. Koyaya, ana tabbatar da sakamakon koyaushe a kan asalin karuwa a cikin babban taro na amitriptyline - northriptyline.
Tare da karuwa da raguwa a sashi, kaddarorin magungunan sun ɗan canza. Don haka, lokacin da kuka isa wani matakin, ayyukan northriptyline yana raguwa, ƙimar amitriptyline yana ƙaruwa. Koyaya, raguwa na tasirin antidepressant wani lokaci ana lura dashi. Saboda wannan, ba za ku iya shan maganin ba da kanku, saboda yana da mahimmanci a zaɓi tsarin kulawa da ya dace da yin la’akari da halayen jiki. Dole ne a ɗauka a zuciya cewa ɗaukar ƙananan allurai ba zai samar da sakamakon da ake so ba.
Tare da amitriptyline, zaku iya sarrafa ƙimar zuciyar ku. Wannan saboda sakamako na antiarrhythmic na miyagun ƙwayoyi.
Magungunan da ake tambaya kuma suna tasiri ga keta ayyukan CCC. Misali, ana iya amfani dashi don sarrafa bugun zuciya. Wannan saboda sakamako na antiarrhythmic na miyagun ƙwayoyi. Lokacin da aka tsara magunguna a allurai na warkewa, an lura da raguwa a cikin ƙarfin aikin ventricular.
Pharmacokinetics
Amitriptyline yana halin saurin sha. Bayan sa'o'i 2-6, ana kaiwa kololuwar ayyukan wannan abu. An bambanta shi da matsakaicin matakin bioavailability (50%). Amma dauri ga sunadaran magani mai girma - 95%. Ganin cewa miyagun ƙwayoyi suna ba da sakamakon da ake so bayan sun isa daidaitawar ɓangaren aiki a cikin jiki, ingantaccen sakamako bai kamata a sa ran farkon mako 1 ba. Wannan ya faru ne saboda gaskiyar cewa ana buƙatar irin wannan lokacin don cika babban yanayin wanda alamun cutar ta fara bacewa.
Mai aiki mai narkewa yana aiki a cikin hanta. Da farko, babban fili, northriptyline, an sake shi. Bayan haka, duka amitriptyline da mai aiki na metabolite suna aiki hydroxylated, tare da sakin abubuwa marasa ƙarfi. Rabin rayuwar miyagun ƙwayoyi ya bambanta daga 9 zuwa 46 hours, wanda ke shafar yanayin jikin, kasancewar wasu cututtukan.
Abin da aka wajabta
Yana da kyau a yi amfani da miyagun ƙwayoyi don raunin kwakwalwa, musamman:
- nau'ikan nau'in damuwa, tare da tashin hankali, damuwa, yayin da ake amfani da miyagun ƙwayoyi a matsayin babban ma'aunin warkewa;
- a matsayin wani ɓangare na maganin rikice-rikice, an tsara maganin maganin cututtukan cututtukan fata a cikin lambobi da yawa: halayyar, phobic, rikicewar motsin zuciya, raguwar mafitsara (enuresis tare da bayyanar da daddare), anorexia, bulimia.
Contraindications
Akwai ƙuntatawa da yawa akan amfani da wannan magani:
- mutum mara kyau amsa ga wani bangaren a cikin abun da ke ciki (aiki da m);
- infarction na zuciya, ciki har da tarihin;
- m ethanol guba;
- yanayin pathological tare da raunin sani;
- guban tare da kwayoyi (maganin rashin ƙarfi, psychotropic ko hypnotics);
- arrhythmia;
- kusantar kusa da kusurwa;
- take hakkin intraventricular, hanyar atrioventricular take;
- cututtukan ƙwayoyin cuta waɗanda ke da alaƙa da rashi lactase, rashin haƙuri a cikin lactose, cutar glucose-galactose malabsorption syndrome;
- matsanancin kira sel a cikin kyallen hanji na prostate, wanda ke kaiwa zuwa ga takaitaccen ƙwayar ƙwayar katuwar ciki;
- ciwon sikila na hanji;
- rage matakan potassium;
- bradycardia.
Tare da kulawa
Yanke contraindications:
- hawan jini;
- yanayin pathological tare da canji a cikin abun da ke ciki da kuma kaddarorin jini;
- increasedara yawan matsa lamba na ciki da sauran cututtuka na gabobin gani;
- kowane ilimin cuta tare da riƙewar urinary;
- katsewa
- schizophrenia
- fargaba
- rashin lafiyar bipolar;
- take hakkin glandar thyroid (hypothyroidism).
Yadda ake ɗaukar Amuni akan Amitriptyline
Zaɓin tsarin kula da jiyya ne da za'ayi la'akari da irin cutar. Yi la'akari da shekaru, digiri na haɓakar ƙwayar cuta, kasancewar ƙuntatawa akan amfanin Amitriptyline Nycomed. Allunan bai kamata a chewed ba. Adana magungunan bayan cin abinci.
Jigilar jigilar manya
Dole ne jiyya ya fara da kashi 50-75 MG. Sannan yana ƙaruwa, idan ya cancanta, ta hanyar 25-50 MG. Ana ɗaukar wannan adadin sau ɗaya kafin lokacin bacci ko kuma ya kasu kashi biyu. Koyaya, ba za ku iya wuce adadin yau da kullun na 200 MG ba. Tsawon Lokaci - watanni 6.
Amitriptyline Nycomed sashi na lokacin regimen ga yara
Sanya tare da enuresis: 25 MG sau ɗaya ga marasa lafiya daga 7 zuwa 12 shekara, fiye da shekaru 12 - 50 MG. Yana da kyau a dauki kudi kafin lokacin kwanciya.
Shan maganin don ciwon sukari
Magungunan da ake tambaya yana rinjayar tasirin da insulin ya nuna, kuma yana iya haifar da canji a cikin taro na glucose. A saboda wannan dalili, a mafi yawan lokuta, ana buƙatar daidaita sashi. Adadin maganin yana da tsari daban-daban.
Nawa inganci ne
Kayan aiki yana ba da tasiri a cikin 'yan makonni. Yana fara aiki a cikin awanni na farko bayan farawar jiyya. Sakamakon sakamako yana ɗaukar kwanaki 1-2.
Yadda za a soke Amitriptyline Nycomed daidai
Don guje wa ciwo cirewa, ana bada shawara don rage kashi a hankali.
Side effects
Dole ne a ɗauka a cikin zuciya cewa ƙwayar da ake magana a kanta na taimaka wa bayyanar halayen halayen da yawa marasa kyau.
Gastrointestinal fili
Nausea, bushewar mucous membranes, canje-canje a cikin tsarin matsi (maƙarƙashiya). Daga tsarin narkewa, alamu na gaba sau da yawa suna faruwa: rashin jin daɗi a cikin bakin, kumburi, ƙonewa. Commonlyarancin kullun, zawo, amai, kumburi harshe, hepatitis, jaundice, toshewar hanji.
Hematopoietic gabobin
Rowarancin ƙasusuwa mai ƙarancin aiki, yanayi da yawa wanda aka samu canji acikin abun da ke cikin jini.
Tsarin juyayi na tsakiya
Weaknessarfi na gaba ɗaya, rashin nutsuwa, rawar jiki, raunin kai da damuwa, rashin kula, magana, ɗanɗano.
Daga gefen metabolism
Canja cikin ci: ƙaruwa, raguwa. Sakamakon haka, nauyin jikin yana ƙaruwa ko ragewa.
Cutar Al'aura
Vasculitis, urticaria, wanda aka nuna ta itching, kurji.
Tasiri kan ikon sarrafa abubuwan inji
A lokacin jiyya, ya kamata ku ƙi fitar da motoci, saboda miyagun ƙwayoyi suna ba da gudummawa ga lalata tsarin jijiyoyi, yana shafar gabobin hangen nesa da ji, kuma yana haifar da raunin hankali.
Umarni na musamman
Maganin yana farawa ne ta hanyar sarrafa karfin jini.
Lokacin canza yanayin jiki, kula ya kamata a kula; motsi mai kaifi ba zai yiwu ba.
Marasa lafiya da suka haura shekara 50 suna da haɗarin kasala.
Wani lokaci yana iya zama dole don sarrafa ƙididdigar jini.
Abubuwan da ke faruwa a cikin Iskanci sun ci gaba har zuwa lokacin da sashin aiki mai aiki ke taimaka wajan rage alamun cutar rashin hankalin.
A cikin samari (har zuwa shekaru 24), haɗarin kashe kansa tare da magani tare da Amitriptyline Nycomed yana ƙaruwa.
Kafin gudanar da babban aiki, hanyoyin hakori, ya kamata ka daina shan maganin.
Yi amfani da lokacin daukar ciki da lactation
Ba a sanya shi ba.
Yi amfani da tsufa
Ya yarda da amfani da maganin maganin kashe kwari da ke tambaya, amma ya kamata a yi taka tsantsan. Kuna buƙatar fara hanya tare da 25-30 MG (sau ɗaya a rana). Theara yawan miyagun ƙwayoyi ya kamata ya zama 1 lokaci kowane kwana 2. Matsakaicin maganin yau da kullun shine 100 MG.
Aikace-aikacen aiki mara kyau
A cikin marasa lafiya da cututtuka na wannan sashin jiki, motsin jiki na aiki na metabolites na Amitriptyline Nycomed daga jiki yana raguwa. Babu madaidaicin takaddun hana shan miyagun ƙwayoyi.
Amfani don aikin hanta mai rauni
An ba da izinin amfani tare da taka tsantsan. Tare da isasshen aikin hanta, an rage kashi.
Yawan damuwa
Yawan adadin amitriptyline na iya haifar da mummunar toshe hanyoyin shiga ciki. Sauran sakamako masu illa suna haɓaka. Jiyya: An wanke ciki don rage yawan cutar mai guba na miyagun ƙwayoyi, an wajabta maganin sihiri, idan ya cancanta, ana gudanar da maganin cholinesterase inhibitors, ana buƙatar matsin lamba, kuma ana kiyaye daidaiton ruwa.
Yin hulɗa tare da wasu kwayoyi
Abubuwan hana ƙwayar cuta na tsakiya suna haɓaka tare da haɗuwa da miyagun ƙwayoyi a cikin tambaya da antipsychotics, magunguna, magungunan ƙwayoyin cuta, maganin motsa jiki, magungunan narkewa.
Tare da Amitriptyline, ba a amfani da masu hana MAO. Ba a so a hada shi da Adrenaline, Ephedrine, Dopamine, Noradrenaline, Phenylephedrine.
Amfani da barasa
Ba a haɗuwa da giya mai amfani da giya da maganin hana ƙwayar cuta ba.
Analogs
Magunguna masu tasiri waɗanda aka yi amfani da su maimakon Amitriptyline Nycomed:
- Anafranil;
- Milipramine;
- Ladisan;
- Doxepin da sauransu
Menene bambanci tsakanin Amitriptyline da Amitriptyline Nycomed
Magungunan tare da ƙaddamar da Nycomed da sunan ba a sanya shi ta hanyar mafita ba. Za'a iya siyan ta a allunan kawai. Amitriptyline yana samuwa a cikin nau'i daban-daban: m, ruwa (allura). Shirye-shiryen wadannan rukunoni suna cikin nau'in farashi ɗaya. Zai iya bambanta cikin adadin kayan aiki mai aiki.
Yanayin hutu Amitriptyline Ya cika daga kantin magani
Magunguna magani ne.
Zan iya siye ba tare da takardar sayan magani ba
A'a.
Farashin don Amintarwa a yanar gizo
Matsakaicin matsakaici shine 60 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Yara suna buƙatar rufe hanya zuwa samfurin. Shawar ajiya na da aka ba da shawarar: + 15 ... + 25 ° С.
Ranar karewa
Magungunan yana riƙe da kaddarorinsa na tsawon shekaru 5 daga ranar da aka sake shi.
Kamfanin samar da Amitriptyline na Nycomed
Takeda Pharma A / S, Denmark.
Ra'ayoyi game da Amitriptyline Nycomed
Masu tabin hankali
Chukhov V.V., likitan kwakwalwa, mai shekara 49, Chelyabinsk
Wani tsohon magani, sabuwa analogues yanzu sun bayyana wanda yawancin halayen marasa kyau zasu iya magani.
Kochev V.O., Likitan hauka, mai shekara 34, Stavropol
Ingancin antidepressant, bugu da remoari yana cire ciwon kai tare da psychosomatics. Zan iya tsokane jinkiri a cikin tsarin fitar fitsari.
Marasa lafiya
Larisa, ɗan shekara 34, Barnaul
Na dauki allunan 10 MG. Tasirin warkewa ya faru ne bayan makonni 3, wanda yayi tsawo. Amma, a ƙarshe, an shawo kan ɓacin rai.
Marina, shekara 41, Moscow
Dauki wannan magani. Sai kawai na dogon lokaci ba na iya tsayar da. Da fari dai, likita ya yi gargadin cewa kyakkyawan sakamako yana faruwa a cikin watan farko bayan fara karatun. Abu na biyu, sakamako masu illa na wannan maganin basu bada izinin ƙarin magani ba.
