An wajabta Janumet 850 don mayar da matakan glucose na jini na yau da kullun. Amfanin magani shine kasancewar a haɗe da aka haɗa kayan da ke nuna tasirin sakamako mai hauhawar jini.
Sunan kasa da kasa mai zaman kansa
Metformin + sitagliptin
An wajabta Janumet 850 don mayar da matakan glucose na jini na yau da kullun.
ATX
A10BD07
Saki siffofin da abun da ke ciki
Akwai bambance bambancen magani guda ɗaya kawai - allunan. Babban abubuwanda aka gyara sune: metformin hydrochloride, sitagliptin phosphate monohydrate. Mayar da hankali daga waɗannan mahaɗan ya bambanta sosai. Kwamfutar hannu 1 ta ƙunshi kashi na metformin - 850 MG, sitagliptin - 50 MG.
Akwai sauran nau'ikan Yanumet. Sun bambanta kawai da sashi na metformin. Yawan wannan abun zai iya zama 500 ko 1000 MG. Cutar da sitagliptin koyaushe shine 50 mg. Kuna iya siyar da magani a cikin kunshin sel. Lambar su a cikin kwali kwali ya bambanta: 1, 2, 4, 6, 7 inji mai kwakwalwa.
Akwai ɗayan juzu'in magungunan Yanumet.
Aikin magunguna
Duk abubuwan haɗin biyu a cikin abun da ya faru na Yanumet suna cikin rukunin wakilai na hypoglycemic. Ana amfani da su a hade, saboda ana nuna su ta hanyar sakamako mai amfani. Yana nufin, metformin yana haɓaka tasirin sitaglipin akan jiki kuma gaba. Lokacin amfani da waɗannan ɗayan waɗannan abubuwa daban-daban, sakamakon magani yana daɗa muni. Ana hada magungunan Yanumet sau da yawa bayan maganin metformin, lokacin da ba zai yiwu a sami ci gaba a yanayin haƙuri ba.
Kowane ɗayan abubuwa yana aiki daban, saboda abubuwan haɗin biyu sun haɗa da rukuni daban-daban na magunguna. Misali, metformin wakili ne na ajin biguanide. Ba ya shafar samar da insulin. Hanyar aiwatar da metformin ta dogara ne akan sauran matakai. Koyaya, tare da magani tare da wannan abun, an lura da karuwa a cikin hankalin mutum zuwa tasirin insulin. Wannan ya faru ne saboda raguwar adadin insulin da ke ɗaure zuwa kyauta. Koyaya, rabo daga insulin zuwa proinsulin yana ƙaruwa.
Metformin yana da fa'ida a kan sauran abubuwa tare da tasirin hypoglycemic. Don haka, wannan bangaren yana shafar metabolism na lipid: yana rage jinkirin hadaddiyar kitse mai mai, yayin da hadawar kitse ke da rauni sosai, wanda ke hana shan su. Don haka, tare da daidaituwa na matakan glucose, akwai raguwa a cikin yawan tasirin mai. Wannan yana kwantar da nauyi.
Wani aikin metformin shine dakatar da aikin glucose a cikin hanta. A lokaci guda, akwai raguwa a cikin yawan karuwar glucose a cikin hanji. Metformin ya bambanta da analogues (abubuwan da aka samo asali na sulfonylurea) a cikin wannan ba ya tsokani ci gaban hypoglycemia. Ganin cewa wannan bangaren ba ya tasiri ga aikin insulin, yuwuwar alamun bayyanar cututtuka na hyperinsulinemia yana da ƙanƙanta sosai.
Duk abubuwan haɗin biyu a cikin abun da ya faru na Yanumet suna cikin rukunin wakilai na hypoglycemic. Ana amfani dasu a hade, metformin yana inganta tasirin sitaglipin da mataimakin.
Babban abu na biyu (sitagliptin) shine mai hana enzyme DPP-4. Lokacin da aka ƙwace shi, ana aiki da tsarin haɗin keɓaɓɓu. Wannan wani sinadari ne wanda ke taimakawa daidaitaccen tsarin sarrafa kansa wanda aka samar da glucose. Ana bayar da ingantacciyar sakamako sakamakon kunnawar kwayar insulin tare da halartar ƙwayar ƙwayar cuta. Koyaya, tsananin yawan aikin glucagon yana raguwa. Sakamakon haɓakar wannan tsari, an lura da hanawar glucose kira.
Pharmacokinetics
Matsakaicin abun ciki na metformin ya kai bayan minti 120 bayan shan maganin. Pharmakoketiket na wannan abu yana haɓaka da sauri. Bayan awanni 6, adadin metformin ya fara raguwa. Wani fasalin wannan abun shine rashin karfin ɗaure shi da kariyar plasma. An bambanta ta da ikon yin hankali a hankali a cikin ƙwayoyin hanta, ƙodan, da kuma ƙari a cikin glandon salivary. Mayar da rabin rabin rayuwan sun bambanta awanni da yawa. An cire Metformin daga jiki tare da halayen kodan.
Dangane da bioavailability, sitagliptin ya wuce abubuwan da aka ambata a sama. Ayyukan wannan siga shine 87 da 60%, bi da bi. Sitagliptin ba shi da talauci. A wannan yanayin, an cire babban kashi na ƙwayoyi daga jikin su a cikin hanyar da ya shiga gabobin narkewa. Rabin rayuwar wannan abu ya fi tsayi kuma shine awanni 12.
Alamu don amfani
An wajabta magungunan don nau'in ciwon sukari na II na ciwon sukari na II. Yanumet ya fi tasiri fiye da magunguna-kayan haɗin kai dangane da metformin ko wasu abubuwa waɗanda ke da tasirin sakamako akan aikin glucose. A saboda wannan dalili, ana amfani dashi lokacin da ba zai yiwu a sami sakamako mai kyau a cikin jiyya na irin ciwon sukari na II na mellitus ba.
An wajabta Janumet don nau'in ciwon sukari na II II.
Ana iya yin maganin Janumet yayin da ake fama da jiyya tare da kwayoyi na ƙungiyar sulfonamide. Ana amfani da kayan aiki a kan tsarin abincin hypocaloric da motsa jiki matsakaici.
Contraindications
Ba za a iya amfani da miyagun ƙwayoyi ba lokacin da mummunan ra'ayi na kowane mutum a cikin abin da ya ƙunshi ya faru. Sauran abubuwan contraindications:
- mummunan yanayin mai haƙuri, mummunar cutar da kodan: rawar jiki, kamuwa da cuta;
- cututtukan tare da raunin zuciya, rauni na jini;
- nau'in ciwon sukari na mellitus;
- barasa;
- ƙaruwar acidity a cikin jini (lactic acidosis).
An wajabta Janumet don ci tare da abinci. Kada ku ƙaura da iyakar adadin yau da kullun na sitagliptin (100 MG).
Tare da kulawa
Marasa lafiya fiye da shekaru 80 ya kamata su yi amfani da miyagun ƙwayoyi tare da taka tsantsan.
Yadda za a ɗauki Janumet 850?
Allunan an wajabta su don amfani da abinci. Kada ku ƙaura da iyakar adadin yau da kullun na sitagliptin (100 MG). Matsayin da aka ba da shawarar na shan maganin shine sau 2 a rana.
Tare da ciwon sukari
Kuna buƙatar fara hanya tare da ƙaramin adadin abubuwan aiki (sitagliptin, metformin): 50 da 500 mg, bi da bi. Ba a canza chanjin shigowa tsawon lokacin magani (sau 2 a rana). Koyaya, kashi na metformin a hankali yana ƙaruwa. Bayan 500 MG, likita ya tsara 850, sannan 1000 MG. Lokacin da ake buƙatar ƙaruwa a cikin ƙwayar ƙwayar ƙwayar cuta an ƙaddara shi daban-daban, saboda ya dogara da yanayin jikin mutum, kasancewar wasu cututtuka.
Sakamakon sakamako na Yanumet 850
Bayyanar cututtuka na tsarin juyayi: nutsuwa, ciwon kai, farin ciki.
Daga tsarin musculoskeletal: ciwon baya, raɗaɗin tsoka.
Kuna buƙatar fara hanya tare da ƙaramin adadin abubuwan aiki (sitagliptin, metformin): 50 da 500 mg, bi da bi. Bayan 500 MG, likita ya tsara 850, sannan 1000 MG.
Gastrointestinal fili
Ciwon ciki, taushin ciki, sako-sako na bakin ciki (na iya musanyawa tare da matsanancin rashin nutsuwa), bushewar bakin. Kadan gama shine kamuwa da amai.
Daga gefen metabolism
Rashin lafiyar Anorexia.
Da wuya - raguwa a cikin glycemia, kuma wannan ba shi da alaƙa da haɗuwa da abubuwa masu aiki waɗanda ke ɓangaren Yanumet. A lokacin gwaji na asibiti, an gano cewa raguwa a cikin glycemia ana haifar da shi ta hanyar halayen jiki ga abubuwan da suka shafi ciki da waje waɗanda basu da alaƙa da miyagun ƙwayoyi.
Halin hauhawar jini a cikin marasa lafiya da ke shan wannan magani daidai yake da a cikin marasa lafiya daga rukunin da aka sanya metformin tare da placebo.
A ɓangaren fata
Rash, itching, kumburi, vasculitis, cututtukan Stevens-Johnson.
Daga tsarin zuciya
Ba a lura.
Cutar Al'aura
Cutar mahaifa, tare da itching, amai, kumburi.
Tasiri kan ikon sarrafa abubuwan inji
Babu irin wannan nazarin da aka gudanar. Koyaya, dole ne a ɗauka cikin tunanin cewa miyagun ƙwayoyi suna tsokani ci gaban da dama daga rikice-rikice na tsarin juyayi na tsakiya (nutsuwa, farin ciki, da sauransu). Saboda haka, dole ne a yi taka tsantsan lokacin tuki motocin.
Umarni na musamman
Akwai bayanai game da alaƙar da ke tsakanin shan ƙwayoyi da haɓakar ciwon ƙwayar cuta. Lokacin da alamun halayen suka bayyana, an dakatar da jiyya tare da Yanumet.
Yayin aikin jiyya tare da wannan kayan aiki, sau ɗaya a shekara, ana kula da alamun ƙodan. Tare da raguwa mai mahimmanci a cikin ɗaukar izinin creatinine, an soke maganin.
Idan ana amfani da Yanumet a lokaci guda tare da insulin ko tare da hanyar rukuni na abubuwan da suka samo asali na sulfonylurea, sashi na ƙarshen yana daidaita (ƙasa).
Akwai bayanai game da alaƙar da ke tsakanin shan ƙwayoyi da haɓakar ciwon ƙwayar cuta. Lokacin da alamun halayen suka bayyana, an dakatar da jiyya tare da Yanumet.
Tare da magani tare da kwayoyi masu dauke da sitagliptin, haɗarin maganganun rashin damuwa yana ƙaruwa. Haka kuma, bayyanar mara kyau bata faruwa kai tsaye, amma bayan 'yan watanni.
Yi amfani da lokacin daukar ciki da lactation
Duk da yake ɗaukar yaro, yana halatta amfani da Yanumet, duk da haka, an tsara wannan magani idan aka tabbatar cewa ingantaccen tasirin yana ƙaruwa da cutarwa mai yiwuwa.
Yayin cikin lactation, ba a amfani da maganin da yake tambaya ba.
Alƙawarin Yanumet ga yara 850
Ba a sanya magani ba.
Yi amfani da tsufa
Ba'a ba da shawarar yin amfani da Janumet ga marasa lafiya da suka girmi shekaru 80 ba. Banda shi ne lokacin da maida hankali kan kwayar halitta a cikin tsofaffi ya kasance a matakin al'ada.
Ba'a ba da shawarar yin amfani da Janumet ga marasa lafiya da suka girmi shekaru 80 ba.
Aikace-aikacen aiki mara kyau
Tare da rauni, matsakaici da mummunar lalacewar wannan sashin, ba a ba da shawarar Janumet ba, saboda a kowane yanayi maida hankali ne a cikin jiki yana ƙaruwa.
Amfani don aikin hanta mai rauni
Babu wani bayani game da dalilin maganin a cikin tambaya tare da raguwa mai yawa a aikin renal. Saboda wannan dalili, ya kamata ka guji shan miyagun ƙwayoyi idan ya kasance cikin rashin isasshen aikin wannan sashin.
Adadin adadin Janumet 850
Babu wani bayani game da ci gaban rikitarwa yayin shan wannan magani. Koyaya, yawan haɗarin metformin yana ba da gudummawa ga abin da ya faru na lactic acidosis. Babban ma'aunin maganin shine maganin hemodialysis. Saboda wannan, haɗakar metformin a cikin jijiyar jini yana raguwa.
Yin hulɗa tare da wasu kwayoyi
An lura da adadin jamiái da abubuwa wanda ingancinsu ke raguwa ƙarƙashin rinjayar Yanumet:
- kamuwa da cuta;
- magungunan glucocorticosteroid;
- maganin halittu;
- kwayoyin hodar iblis;
- phenytoin;
- nicotinic acid.
Hada Janumet da abubuwan sha masu dauke da giya kada su kasance. Alcohol yana haɓaka tasirin metformin akan hanyoyin haɓaka wanda ke da alaƙa da canjin lactic acid.
Kuma, akasin haka, tare da yin amfani da lokaci ɗaya tare da insulin, NSAIDs, MAO inhibitors da ACE inhibitors, wakilai na hypoglycemic, karuwa da yawaitar tasirin Janumet a jiki.
Amincewa da furosemide shine dalilin karuwar ninki biyu na manyan abubuwanda ake wakilta a tambaya.
Ayyukan Digoxin yana ƙaruwa yayin jiyya tare da Yanumet.
Hankalin sitagliptin yana ƙaruwa yayin ɗaukar Cyclosporin da Yanuvia.
Amfani da barasa
Hada Janumet da abubuwan sha masu dauke da giya kada su kasance. Alcohol yana haɓaka tasirin metformin akan hanyoyin haɓaka wanda ke da alaƙa da canjin lactic acid.
Analogs
Akwai ɗimbin lambobi waɗanda zasu bambanta a cikin aikin aikinsu da abubuwan da aka tsara. Lokacin zabar, yakamata mutum yayi la’akari da matsayin tsananin tasirin tasirinsu ga jiki, da kuma nau'in sakin. Matsaloli da ka iya yiwuwa
- Gluconorm;
- Glucovans;
- Glibomet;
- Galvus Met et al.
Na farko daga cikin waɗannan abubuwa shiri ne guda biyu, amma ya ƙunshi metformin da glibenclamide. Na biyu na abubuwan yana nufin abubuwan da suka samo asali na sulfonylurea, wanda ke nufin cewa tare da wannan magani, haɗarin sakamako masu illa yana ƙaruwa. Gluconorm ya bambanta da Yanumet ta yadda ba za a iya amfani da shi yayin daukar ciki da lokacin shayarwa ba. Farashin wannan maganin yana da ƙasa (250 rubles).
Glucovans alama ce ta Gluconorm. Abunda ya haɗa ya hada da metformin da glibenclamide. Za'a iya amfani da maganin don maye gurbin Janumet, idan babu magungunan rikice-rikice. Koyaya, bai kamata a yi amfani dashi maimakon Gluconorm ba.
Glibomet ya ƙunshi metformin da glibenclamide. Hankalin abubuwan abubuwa masu aiki na iya bambanta dan kadan, yana ƙaruwa ko rage girman tasirin miyagun ƙwayoyi akan jikin, wanda yakamata a la'akari dashi, tunda koda karamin canji a cikin yanayin shan magungunan hypoglycemic zai iya haifar da ci gaban rikice-rikice.
Galvus Met ya bambanta a cikin kayan haɗin. Ya ƙunshi metformin da vildagliptin. Kamar yadda a lokuta da suka gabata, kashi na metformin ya wuce adadin babban kashi na biyu. Ba za a iya amfani da miyagun ƙwayoyi ba lokacin daukar ciki da kuma lactation. Koyaya, ana iya amfani dashi tare da insulin, kwayoyi daga ƙungiyar abubuwan samo asali na sulfonylurea.
Galvus Met ya ƙunshi metformin da vildagliptin, ana iya amfani dashi tare da insulin, kuɗi daga ƙungiyar abubuwan samo asali na sulfonylurea.
Magunguna kan bar sharuɗan
Magunguna magani ne.
Zan iya saya ba tare da takardar sayan magani ba?
Babu yuwuwar haka, alƙawarin likita ya zama tilas.
Farashi na Janumet 850
Kuna iya siyar da samfurin akan farashin 2800 rubles.
Yanayin ajiya na miyagun ƙwayoyi
An bada shawara don kula da yawan zafin jiki na ɗakin a cikin + 25 ° С.
Ranar karewa
Shirye-shiryen da ya ƙunshi 850 da 50 MG na abubuwa suna riƙe da kaddarorin na ɗan gajeren lokaci fiye da misalin 500 da 50 MG Rayuwar rayuwar shiryayye na samfurin shine shekaru 2.
Mai masana'anta
Kamfanin "Pateon Puerto Rico Inc." a cikin Amurka.
Ra'ayoyi game da Yanumet 850
Valeria, ɗan shekara 42, Norilsk
Na gano cutar ta lokaci mai tsawo, tun daga wannan lokacin yawanci nake shan magungunan hana haihuwa. A cikin lokacin lalacewa, kwayoyi guda ɗaya suna taimakawa mara kyau. A irin waɗannan lokutan, likita ya ba da shawarar shan Janumet. Yana taimakawa kusan nan da nan, amma aikinsa da sauri yana raguwa. Bugu da kari, farashin maganin yana da yawa.
Anna, 39 years, Bryansk
Kayan aiki yana da tasiri, Ina ajiye shi a gida a cikin majalisar ministocin. Ina kuma son tasirin duniya: nauyin daidaitawa, matakan glycemia na haɓaka, ƙirar insulin ba ta jawowa. Na yi imani da cewa amfani da shi ƙari ne kawai, idan ba ka keta tsarin magani ba.
