Yadda za a yi amfani da miyagun ƙwayoyi NovoMix 30 Penfill?

NovoMix 30 Penfill magani ne na hypoglycemic dangane da aikin nau'ikan insulin guda biyu. Jigilar ƙwayar ƙwayar ƙwayar cuta a cikin gajeren lokaci yana ba da gudummawa ga saurin nasara na tasirin warkewa, yayin da insulin tare da matsakaicin tsawon lokaci yana ba ku damar kula da tasirin hypoglycemic yayin rana. An haramta amfani da insulin na jiyya don amfani da marassa lafiyar thean shekaru 18 kuma an ba shi izinin amfani da shi ta hanyar masu juna biyu, masu shayarwa.

Sunan kasa da kasa mai zaman kansa

Biphasic na jikin insulin.

NovoMix 30 Penfill magani ne na hypoglycemic dangane da aikin nau'ikan insulin guda biyu.

ATX

A10AD05.

Saki siffofin da abun da ke ciki

Form sashi - dakatarwa don gudanar da subcutaneous. 1 ml na ruwa ya ƙunshi 100 IU na haɗin gwal mai aiki, wanda ya ƙunshi 70% na protamine na insulin a cikin nau'ikan lu'ulu'u da kashi 30% na insulin na narkewa mai narkewa. Don haɓaka ƙimar magunguna, ana ƙara abubuwa masu taimako ga abubuwa masu aiki:

• glycerol;
• carbolic acid;
• sodium chloride da zinc;
• metacresol;
• sinadarin hydrogen phosphate mai narkewa;
• furotin protamine;
• sodium hydroxide;
• 10% hydrochloric acid;
• bakararre ruwa don allura.

An rufe magungunan a cikin katako na mil 3 dauke da IU 300 na abubuwa masu aiki. Hakanan ana samun NovoMix Penfill (Flexpen) a cikin nau'in alkalami na sirinji.

Aikin magunguna

NovoMix yana wakiltar insulin kashi biyu ne, wanda ya kunshi analogues na hormone na mutum:

• 30% mai narkewa mai gauraya aiki;
• Kirarin insulin na protine 70% tare da tasirin tsawon lokaci.

NovoMix yana gabatar da insulin biphasic.

An samar da insulin kamar yadda yake amfani da fasaha na ma'adanin halittar DNA daga nau'in yisti mai gasa.

Sakamakon rashin lafiyar hypoglycemic shine saboda ɗaurewar kewayon mai karɓar insulin a kan ƙwayar myocytes da ƙwayoyin tsopose nama. A cikin layi daya, hana gluconeogenesis a cikin hanta ya faru kuma jigilar glucose ta cikin jini yana ƙaruwa. Sakamakon cimma sakamako na warkewa, kyallen jikin mutum ya fi dacewa yalwaci sukari kuma ya sarrafa shi zuwa makamashi.

Ana lura da tasirin miyagun ƙwayoyi na mintina na 15-20, yana isa mafi girman sakamako bayan sa'o'i 2-4. Tasirin hypoglycemic yana tsawon awanni 24.

Pharmacokinetics

Sakamakon kasancewar acid aspartic, insulin aspart shine kashi 30% cikin nagarta sosai a cikin fitsarin fatar jiki, akasin insulin abinci mai narkewa. Lokacin da suka shiga cikin jini, abubuwa masu aiki sun isa mafi yawan taro a cikin jini a cikin mintina 60. Cire rabin rayuwar yayi mintina 30.

Masu nuna insulin suna komawa ga ainihin darajar su a cikin sa'o'i 15-18 bayan gudanarwar sc. Magungunan ƙwayar cuta suna metabolized a cikin hanta da kodan. Kayayyakin ƙwayoyin cuta suna barin jiki saboda narkewar ƙasa.

Lokacin da suka shiga cikin jini, abubuwa masu aiki sun isa mafi yawan taro a cikin jini a cikin mintina 60.

Alamu don amfani

An wajabta maganin insulin don halaye masu zuwa:

• insulin dogara da ciwon sukari;
• cututtukan da ba su da insulin-insulin tare da ƙuntataccen abinci mai gina jiki, karuwar motsa jiki ta jiki da sauran matakan rage nauyin jiki.

Contraindications

Ba a ba da izinin yin maganin ba ga mutanen da ke da yawan haɗari ga abubuwan da ke cikin sunadarai waɗanda ke haɗuwa da wakili na hypoglycemic. Wannan nau'in insulin bai dace da mutanen da ke ƙasa da shekara 18 ba.

Tare da kulawa

Marasa lafiya marasa aikin yi na hanta da kodan yayin aikin insulin ya buƙaci kula da yanayin gabobin lokaci zuwa lokaci. Rashin aikinsu na iya haifarda baƙin jini insulin metabolism.

Mutanen da ke fama da rikice-rikice na kwakwalwa da ƙwaƙwalwar ajiyar zuciya ya kamata su mai da hankali.

Mutanen da ke da matsala na jijiyoyin kwakwalwa ya kamata su mai da hankali.

Yadda ake ɗaukar NovoMix 30 Penfill

Ana amfani da miyagun ƙwayoyi ne kawai a ƙarƙashin ƙasa. An haramta amfani da intramuscularly da cikin ciki saboda yuwuwar faruwar cutar sikari.

Sashi ne da likita ya ƙayyade gwargwadon abubuwan da ke nuna alamun sukari na jini da buƙatar haƙuri ga insulin. Marasa lafiya da ke fama da rashin lafiyar insulin-da ke fama da cutar insulin-insulin ana iya tsara su kamar NovoMix a matsayin monotherapy tare da insulin kuma a hade tare da wakilai na hypoglycemic. Don nau'in ciwon sukari na 2, ana bada shawara don fara amfani da NovoMix tare da sashi na raka'a 6 da safe kafin abinci da maraice. An yarda da allura tare da raka'a 12 na miyagun ƙwayoyi don yin allura guda ɗaya kowace rana kafin abincin dare.

Hanyar hadawa ta insulin

Kafin amfani, tabbatar cewa zazzabi da abin da ke cikin kundin ya dace da zazzabi na yanayin. Bayan haka, haɗu da insulin bisa ga algorithm mai zuwa:

1. Amfani da farko, mirgine kundin sau 10 tsakanin tafin hannu a cikin sararin sama sau 10.
2. Theauki katako a tsaye sau 10 kuma runtse shi a sararin sama saboda ƙwallon gilashi na motsawa gaba ɗaya tsawon katif ɗin. Don yin wannan, ya isa don tanƙwara hannu a cikin gwiwar hannu.
3. Bayan an kammala amfani da wannan jan, dakatarwar ta zama mai duhu kuma ta sami farin farin. Idan wannan bai faru ba, ana maimaita hanyoyin hadawa. Da zarar ruwan magani ya gauraye, dole ne a saka insulin nan da nan.

Kowane gabatarwar an yi shi da sabon allura.

Don gabatar da mafi ƙarancin 12 BAYANAN abubuwa masu aiki. Idan ƙimar insulin ta kasance ƙasa, to kuna buƙatar maye gurbin kicin ɗin da sabuwa.

Yadda za a yi amfani da alkairin sirinji

Kafin amfani da alƙalami, duba yarda da nau'in insulin. Kafin allura ta farko, an gauraya a ko'ina.

Kowane gabatarwar an yi shi da sabon allura. Canjin kashi ya zama dole don rage yiwuwar kamuwa da cuta. Kafin amfani, tabbatar cewa allura ba ta lanƙwasa ko lalacewa. Don haɗa allura, kuna buƙatar bin algorithm mai zuwa:

1. Cire murfin kariya daga abin da za'a iya kashewa, sannan ka ɗaura allura a maɓallin sirinji.
2. An cire hula ta waje amma ba a jefar dashi ba.
3. Suna kawar da kan abin da ke ciki.

Duk da ingantaccen aikin NovoMix, iska na iya shiga kicin din. Saboda haka, kafin amfani da alkairin sirinji, ya zama dole don hana shigowa cikin nama ta hanyar yin amfani da waɗannan jan hankula:

1. Kira lambobi 2 tare da zaɓin sashi.
2. Yayin riƙe FlexPen madaidaiciya tare da allura sama, matsa sauƙaƙe a kan kabad tare da yatsanka sau 4-5 don abin da iska zai motsa zuwa saman kicin.
3. Ci gaba da riƙe alkalami na tsaye, tura bututun mai har zuwa kullun. Bincika cewa mai zaɓin kashi ya koma matsayin 0 kuma digon magani ya bayyana a saman allura. Idan babu magani, to kuna buƙatar maimaita hanya. Idan, bayan sau 6, insulin bai shiga ta allura ba, wannan yana nuna rashin lafiyar FlexPen.

Kafin amfani, tabbatar cewa allura ba ta lanƙwasa ko lalacewa.

An saita sashi ta amfani da mai zaɓin sashi, wanda yakamata ya kasance cikin matsayi 0. Mai zaɓar don tantance sashi zai iya juyawa ta kowane irin agogo da agogo baya. Amma a cikin tsari kuna buƙatar yin hankali - ba za ku iya danna bawul ɗin farawa ba, in ba haka ba za'a sami sakin insulin. Lambar 1 tayi daidai da naúrar 1 na insulin. Kada ku sanya sashi na adadin insulin da ya rage a cikin kicin.

Don aiwatar da allura, kuna buƙatar latsa maɓallin jawo har sai an nuna matsayin 0 akan mai zaɓa kuma allura ta zauna a fata. Bayan sanya matsayin sifilin akan mai zaɓa, bar allura a fata don aƙalla 6 seconds, saboda abin da za'a gabatar da insulin gabaɗaya. A yayin gabatarwar, dole ne a bar mai zabi ya juya, domin idan ya juya, insulin din ba zai fito ba. Bayan aikin, sanya allura a cikin matatar waje kuma a kwance.

Sakamakon sakamako na NovoMix 30 Penfilla

Abubuwan da ba su dace da halayen marasa kyau a yawancin halayen suna tsokani da zaɓi na sashi mara kyau ko amfani da miyagun ƙwayoyi.

A wani bangare na bangaren hangen nesa

Rashin maganin cututtukan cututtukan mahaifa yana haɗuwa tare da haɓakar kurakurai masu narkewa da kuma maganin cututtukan fuka.

Tsarin juyayi na tsakiya

Rashin damuwa da tsarin juyayi ana bayyana shi a cikin lokuta mafi wuya ta hanyar bayyanar polyneuropathy na yanki. Wataƙila ci gaban rashin farin ciki da ciwon kai.

NovoMix 30 Penfill na iya haifar da kazanta.

A ɓangaren fata

Ya kamata a sanya allurar ciki a cikin bangarori daban-daban a cikin yanki iri ɗaya don hana ci gaban lipodystrophy. Wataƙila bayyanar halayen a wurin allurar - kumburi ko jan launi. Bayyanar bayyanar cututtuka a cikin hanyar rashes ko itching tafi da kansu lokacin da rage rage ko magani na soke.

Daga tsarin rigakafi

Rashin rigakafin rigakafi yana tare da bayyanar:

• urticaria;
• fata mai ƙyalli;
• kurji
• raunin narkewa;
• wahalar numfashi
• ƙara yin gumi.

Daga gefen metabolism

Ana haifar da rikicewar metabolism da asarar sarrafa glycemic. Ba a cire ci gaban hypoglycemia ba, musamman tare da amfani da keɓaɓɓen amfani da magungunan maganganu na baka.

Marasa lafiya waɗanda ke da alaƙa ga halayen anaphylactic suna cikin haɗarin haɓakar girgiza kwafin anaphylactic.

Cutar Al'aura

A cikin marasa lafiya sun yanke shawarar aukuwar halayen anaphylactic, akwai haɗarin girgiza ƙwayar cuta anaphylactic, angioedema na harshe, amai, da maƙogwaro. Tare da rashin yarda da juna ga kayan aikin, abubuwan fata na iya faruwa.

Umarni na musamman

Tare da rashin isasshen sashi na wakili na hypoglycemic ko tare da cirewa mai kaɗa daga jiyya, hyperglycemia na iya haɓaka. Babban taro mai narkewa na glucose na iya haifar da ketoacidosis mai ciwon sukari idan mara lafiya bai sami magani da ya dace ba. Hadarin da ke tattare da tsarin cututtukan cuta yana ƙaruwa a cikin marasa lafiya da masu ciwon sukari na 1. Hyperglycemia shine halin bayyanar irin waɗannan alamun:

• matsananciyar ƙishirwa;
• polyuria tare da karuwar urination;
• jan, fata, busassun fata;
• tashin hankalin bacci;
• kasala mai wahala;
• tashin zuciya da amai;
• bushe mucous membranes a cikin bakin;
• warin acetone yayin cinyewa.

Hyperglycemia yana nuna bayyanar tsananin ƙishirwa.

Hyperglycemia yana halin halin tashin zuciya da amai.

Hyperglycemia ana nuna shi ta hanyar damuwa.

Hyperglycemia ana saninsa da gajiya mai wahala.

Tare da ƙara yawan aiki na jiki, rashin yarda da hanyoyin rage cin abinci ko tsallake allura, ƙwanƙwasa jini na iya haɓaka.

Yi amfani da tsufa

Marasa lafiya shekaru 65 da haihuwa basa buƙatar daidaita sashi.

Alƙawarin NovoMix 30 Penfil ga yara

An haramta yin allurar miyagun ƙwayoyi a cikin yara 'yan ƙasa da shekaru 18 saboda karancin bayanai akan tasirin insulin akan aikin gabobin yara da matasa.

Yi amfani da lokacin daukar ciki da lactation

Maganin insulin yana taimakawa sosai rage sukari ga mata yayin daukar ciki. Bangaren insulin din ba zai shafi ci gaban halitta na amfrayo kuma baya haifar da rashin lafiyar ciki. Magungunan ba ya shiga cikin madara, saboda haka ana iya amfani dashi lokacin shayarwa.

Yawan adadin NovoMix 30 Penfill

Tare da cin zarafin maganin shaye-shaye, alamu na yawan abin sama da ya kamata na iya faruwa. Hoton asibiti ana nuna shi ta hanyar ci gaba na hankali ko haɓaka na ƙwanƙwasa jini, ya danganta da yadda ake sarrafawa. Tare da raguwa kaɗan na sukari, zaku iya kawar da tsarin cututtukan da kanku ta hanyar sanya sukari, kayan kwalliya ko abinci mai ɗauke da ƙwayar carbohydrate. Sakamakon yiwuwar faruwar cututtukan jini, ana bada shawara ga masu ciwon sukari su ɗauki abinci mai-sukari tare da su.

Game da cutar hypoglycemia mai tsanani, mara lafiyar ya rasa hankali.

Game da cutar hypoglycemia mai tsanani, mara lafiyar ya rasa hankali. A lokacin gaggawa, ana buƙatar yin allura ta wucin gadi ko kashi biyu na 0.5 ko 1 na glucagon ƙarƙashin yanayin tsaye; ana iya gudanar da maganin 40% na dextrose a cikin ciki idan ba a dawo da hankalin mai haƙuri ba.

Yin hulɗa tare da wasu kwayoyi

Babu rashin daidaituwa na asibiti na NovoMix tare da wasu kwayoyi da aka bayyana yayin gwaji na asibiti. Amfani da daidaici na wasu magunguna yana haifar da karuwa ko raguwa a cikin tasirin hypoglycemic.

Amfani da barasa

Ethanol yana ba da gudummawa ga asarar glycemic iko. Barasa yana haɓaka ko ya raunana sakamakon ƙwayar, saboda haka bai kamata ku sha barasa ba lokacin magani.

Amfani da daidaici na wasu magunguna yana haifar da karuwa ko raguwa a cikin tasirin hypoglycemic.

Analogs

Sauyawa zuwa wani nau'in insulin ana aiwatar dashi a karkashin kulawar likita mai tsafta. Daga analogues bambanta:

• Vosulin;
• Gensulin;
• Insavit;
• Insugen;
• Insuman;
• Mikstard;
• Humodar.

Magunguna kan bar sharuɗan

Za'a iya siye magunguna kawai ta hanyar takardar sayan magani.

Zan iya siye ba tare da takardar sayan magani ba

Tare da yin amfani da miyagun ƙwayoyi, mummunan hypoglycemia na iya haɓaka, sabili da haka, an haramta maganin insulin ba tare da alamun likita kai tsaye ba.

Farashi

Matsakaicin matsakaici ga wakilin hypoglycemic shine 1821 rubles.

Yanayin ajiya na miyagun ƙwayoyi

Ana ajiye katako a cikin wuri mai duhu a zazzabi na + 2 ... + 8 ° C ba tare da daskarewa ba.

Ranar karewa

Shekaru 2

Mai masana'anta

Novo Nordisk, Denmark.

Nasiha

Tatyana Komissarova, mai shekaru 22, Yekaterinburg

A lokacin daukar ciki, akwai cututtukan ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa na ciki, saboda wanda na bi ingantaccen tsarin abinci tare da ajiye kundin tarihi da lissafin raka'a gurasa. Amma wannan bai taimaka ba: bayan cin sukari ya tashi zuwa 13 mmol. Kwayar halittar endocrinologist ta wajabta maganin insulin na NovoMix, kuma ta hana shan kwayoyin maganin hyperglycemia. Farashin sau 2 a rana 5 mintuna kafin abinci da raka'a Levemir 2 kafin lokacin kwanciya. Na koyi yin amfani da alkalami na syringe, saboda ya fi dacewa da injections. Iya warware matsalar ba ya haifar da ƙonewa, amma raunin da ya faru wasu lokuta. Suga sukari ya dawo nan da nan. Na bar kyakkyawan nazari.

Stanislav Zinoviev, dan shekara 34, Moscow

Shekaru 2 yana allurar NovoMix. Ina da nau'in ciwon sukari na 2, saboda haka ina amfani da alkalami kawai kuma ban sha magungunan ba. Magungunan yana rage sukari zuwa 6.9-7.0 mmol kuma yana riƙe awanni 24. Idan kun tsallake allura, to wannan ba mahimmanci bane - ana iya amfani da maganin a hade tare da sauran nau'ikan insulin.Babban abu shine kashi ya kamata ya bi umarnin.