Bayyana sakamakon bincike don haemoglobin mai glycosylated: me yasa mai nuna alama ya karu ko ya ragu kuma me yasa yake da haɗari?

An bincika bincike don tabbatar da maganin gemocosylated haemoglobin ana ɗayan ɗayan mahimman hanyoyin. Muhimmiyar mahimmanci ga mutanen da ke fama da rashin lafiya irin su ciwon sukari.

Amfaninsa shine cewa bayyana sakamakon don haɓakar glycosylated yana taimakawa wajen yanke hukunci nan da nan sanadin karuwar glucose.

Yanke mahimmancin ƙididdigar bincike don maganin gemocosylated haemoglobin

Hemoglobin wani sinadari ne wanda aka sanya shi a cikin kwayoyin jini wanda ke samar da iskar oxygen zuwa sel a jikin mutum. Hakanan yana haɗuwa tare da kwayoyin glucose, saboda haka kasancewar irin wannan abu kamar glycosylated haemoglobin.

Akwai manyan nau'ikan haemoglobin guda uku:

• HbA1a;
• HbA1b;
• kazalika da HbA1c.

Hanya ce ta ƙarshe wacce ke nuna alamun kasancewar ƙayyadaddun kasancewar ko rashin kasancewar irin wannan sankarar kamar ciwon suga. Babu wata matsala ta musamman wajen rarrabe abubuwan da aka ƙaddamar da wannan alamar.

Duk dabi'un HbA1c da ke nuna matakan glucose na jini ana ɗaukar su ta waɗannan matakan:

• daga 4 zuwa 6%. Tare da irin waɗannan alamun, babu karkacewa daga al'ada, duk tafiyar matakai na rayuwa suna ci gaba kamar yadda aka saba. Babu ciwon sukari mellitus;
• daga 6 zuwa 7%. Wani cutar sankarau ya bayyana. Hadarin ciwon sukari ya karu;
• daga 7 zuwa 8%. A wannan matakin glucose, ciwon sukari na iya haifar da rikitarwa wanda ke da haɗari ga jiki;
• 10% kuma mafi girma. Tare da wannan manuniya, wani nau'in sikelin da ke haifar da ciwon sukari yana tasowa, wanda ba za'a iya magance rikicewar rikice rikice ba.

Norms da shekaru

Tsarin HbA1c ya dogara ne akan shekarun mutum, amma kuma akan jininsa. A matsakaici, ana nuna mai nuna alama daga 4 zuwa 6%. A matsayinka na mai mulki, maza suna da dan kadan sama da mata.

Al'adun su shine 135 g a lita 1. Samari da ke ƙasa da shekara 30 suna da matakin glucose na 4-5.5%. Har zuwa shekara 50, ana nuna 6.5% a matsayin al'ada, amma ga tsofaffi maza daga shekaru 50 zuwa sama zai zama 7%.

Bayan shekaru 40, wakilai da yawa na masu ƙarfin jima'i suna fara samun wuce kima, wanda hakan na iya nuna rashin lafiyar na rayuwa. Kuma ya zama shine tushen ciwon sukari. Sabili da haka, a wannan zamani, ana bada shawara don saka idanu da lokaci-lokaci don gudanar da bincike wanda ke tantance taro na glucose.

Mata ba su da bambance-bambance masu yawa daga tsarin maza. Karkashin shekaru 30, suna daga 4 zuwa 5%. Daga shekaru 30 zuwa 50, matakin ya zama 5-7%, kuma ga mata bayan shekaru 60, ba a yarda raguwa a ƙasa da 7%.

A cikin yara, komai ya bambanta. A cikin watanni 12 na farko na rayuwa, matakan glucose na al'ada ya kamata ya zama tsakanin 2.8 da 4.4 mmol / L. Daga shekara 1 zuwa shekaru 5, manuniya yana ƙaruwa daga 3.3 zuwa 5 mmol / L. Bayan shekaru 5, ana lissafta kuɗin daidai kamar yadda yake a cikin manya.

Dalilai don rage nuna alama a ƙasa na al'ada

Matsayin haemoglobin na glycosylated na iya raguwa saboda yanayi mai zuwa:

• tsawan jini mai tsawan jini (hypoglycemia);
• anemia ko cutar hauka. Kwayoyin HbA1c na Glycosylated suna mutuwa da haihuwa saboda raguwa a cikin matsakaicin lokacin sel sel jini;
• profuse zubar jini. Akwai asara ba kawai na haemoglobin na al'ada ba, har ma da glycosylated;
• zub da jini. Tushewar HbA1c yana faruwa tare da juzu'i na al'ada, ba tare da carbohydrates ba.

Me yasa farashin ya karu?

Babban dalilin haɓaka mai nuna alama ya ta'allaka ne ga cin zarafin ƙwayoyin carbohydrate. Wadannan abubuwan kuma suna tasiri:

• nau'in ciwon sukari guda 1. Sakamakon karancin insulin a cikin jiki, gazawar amfani da carbohydrates yana faruwa. A sakamakon haka, yawan haɗuwar glucose ya tashi;
• nau'in ciwon sukari na 2. Malfunctions a cikin yin amfani da glucose suna faruwa ko da tare da samar da insulin na al'ada;
• ba ta wajabta magani ba tare da karuwar carbohydrates. Hakanan akwai abubuwanda basu da alaqa da matakan glucose a jiki;
• giya barasa;
• anemia wanda aka kafa akan asalin rashi na baƙin ƙarfe;
• gubar gishiri;
• baƙin ciki cire. Wannan sashin jiki shine babban wurin da amfani da carbohydrate. Sabili da haka, a cikin rashi, tsawon rayuwar su yana ƙaruwa, wanda kuma yana haifar da karuwa a cikin HbA1c;
• uremia. Rashin aiki na ƙarancin ƙwayar cuta yana ba da gudummawa ga babban adadin metabolism da bayyanar carbohemoglobin, kama a cikin kaddarorin zuwa glycosylated;
• ciki A wannan yanayin, za a yi la'akari da kewayon alamun daga 4, 5 zuwa 6, 6% na al'ada. A cikin lokacin balaga yayin daukar ciki, matakin na 7.7% za a yi la'akari da shi a matsayin al'ada. Ya kamata a ba da bincike sau ɗaya a cikin watanni 1, 5. Sakamakon binciken ya ƙayyade ci gaban yaro.

Yaya ake daidaita matakan HbA1c a cikin jini?

Idan binciken ya nuna karkacewa da al'ada ta gemocosylated haemoglobin, to, abu na farko da yakamata ayi shine ka ziyarci mahaukacin ilimin halittar dabbobi.

Kwararren likita tare da taimakon magani zai taimaka wajen dawo da wannan manuniya a al’ada. A matsayinka na mai mulki, babban karkacewa daga dabi'un yana nuna alamun rashin aiki a cikin jiki.

Lokacin da aka wuce kima HbA1c, ana kiyaye waɗannan ƙa'idodi:

• abincin tilastawa;
• sake hutawa sau da yawa kuma ka guji yin aiki mai tsauri;
• matsakaici da aiki na yau da kullun;
• tsarin sarrafa allunan sukari da rage allurar insulin;
• kulawar glycemia a gida. Idan ana so, zai yuwu a gudanar da hadaddun magani tare da magungunan mutane. Ba a yarda da raguwa mai yawa a cikin glycosylated haemoglobin ba, yayin da jikin ya kamu da cutar hauka.

Glycosylated haemoglobin da sukari na jini: menene dangantakar

Hanyar da aka samu ta ci gaba a hankali kuma kai tsaye ya dogara da yawan sukari a cikin jini.

Abun kirkirar amino acid da glucose ne, wanda ke samar da takamaiman aiki. Yawan da saurin haemoglobin suna da alaƙa da matakin sukari, wanda aka kiyaye shi cikin jini a duk tsawon rayuwar "rayuwar" sel sel ja.

Increasedaruwar glucose mai haɓaka yana haɗuwa da haɓakar haɗuwa da gemocosylated haemoglobin. Kamar yadda kuka sani, karuwa a cikin sukari yana haifar da ciwon sukari. Tsarin hada glucose da kwayoyin haemoglobin ya zama cikin sauri, wanda ya hada da karuwa a matakin HbA1c.

A cikin marasa lafiya da ciwon sukari mellitus, karuwarsa sau 2-3 ya fi yadda aka saba. A cikin gano wannan cutar, alamarin HbA1c yana da mahimmanci, tunda yana ba ka damar gano cutar a farkon matakin haɓaka.

Bidiyo masu alaƙa

Menene bincike-binciken jini na haemoglobin ya nuna? Game da sauya fasalin darasi a cikin bidiyon:

Binciken glycosylated haemoglobin a magani yana da fa'idodi da yawa akan sauran nazarin sukari na jini. Da farko dai, ana rarrabe shi ta babban ingancin binciken, yana tantance haɓakar ciwon sukari a farkon matakin, kuma yana kula da ingancin cikar magungunan likita ta masu ciwon sukari.

Wannan bincike yana da damar tantance sukarin jini a cikin watanni ukun da suka gabata. Koyaya, bincike ba zai iya maye gurbin ƙudurin sukari tare da glucometer ba. Sabili da haka, duka nazarin ana ba su a hade.