Gliclazide MV shine ɗayan magungunan da aka fi amfani dasu don ciwon sukari na 2. Ya kasance na ƙarni na biyu na shirye-shiryen sulfonylurea kuma ana iya amfani dashi duka a cikin monotherapy kuma tare da sauran allunan rage sukari da insulin.
Bugu da ƙari ga tasirin sukari na jini, gliclazide yana da tasiri mai kyau a cikin abubuwan da ke tattare da jini, yana rage damuwa oxidative, inganta microcirculation. Magungunan ba tare da lalacewarsa ba: yana ba da gudummawa ga samun nauyi, tare da tsawanta amfani, allunan sun rasa tasiri. Koda kadan yawan abin shafawa na gliclazide yana da kashi tare da hypoglycemia, haɗarin yana da girma musamman a cikin tsufa.
Babban bayani
Shafin rajista na Gliclazide MV ne kamfanin kamfanin Russia na Atoll LLC ya bayar. Magungunan a karkashin kwangilar ne kamfanin samarda magunguna na Samara Ozone ya samar. Yana samarwa da kuma tattara Allunan, kuma yana sarrafa ingancin su. Gliclazide MV ba za a iya kiranta da magani na cikin gida gaba daya ba, tunda ana sayan magunguna ne a kansa (gliclazide iri ɗaya) a China. Duk da wannan, babu wani mummunan abu da za a iya faɗi game da ingancin ƙwayoyi. A cewar masu ciwon sukari, ba mafi muni ba tare da Faransawa masu ciwon sukari tare da wannan abun da ke ciki.
Rashin raguwa na MV da sunan miyagun ƙwayoyi yana nuna cewa abu mai aiki a ciki an gyara shi, ko tsawaita shi, saki. Glyclazide ya bar kwamfutar hannu a lokacin da ya dace kuma a inda ya dace, wanda ke tabbatar da cewa bai shiga cikin jini kai tsaye ba, amma a cikin kananan bangarori. Saboda wannan, ana rage haɗarin sakamako marasa amfani, ana iya ɗaukar miyagun ƙwayoyi ba sau da yawa. Idan aka keta tsarin kwamfutar hannu, aikinta ya ɓace, saboda haka, umarnin don amfani baya bada shawara a datse shi.
An haɗa Glyclazide a cikin jerin magunguna masu mahimmanci, don haka endocrinologists suna da damar da za a iya tsara shi ga masu ciwon sukari kyauta. Mafi sau da yawa, bisa ga takardar sayan magani, MV Gliclazide ne na gida wanda yake analog na ainihin masu ciwon sukari.
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
Alamu don amfani da miyagun ƙwayoyi Glyclazide
Glyclazide ya ba da izinin amfani kawai tare da nau'in ciwon sukari na 2 kuma kawai a cikin marasa lafiya na manya. An tsara shi lokacin da canje-canje a cikin abinci mai gina jiki, asarar nauyi da ilimin jiki ba su isa ga al'ada ta glycemia ba. A miyagun ƙwayoyi na iya rage matsakaicin sukari na jini, don haka rage haɗarin cututtukan angiopathy da alaƙa da alaƙa da rikice-rikice na ciwon sukari.
A farkon nau'in cuta ta 2, kusan kowane mai ciwon sukari yana da abubuwan da ke haifar da tsabtace tasoshin jini daga glucose: insulin juriya, wuce kima nauyi, ƙarancin motsi. A wannan lokacin, ya ishe wa mara lafiya damar canza salon rayuwarsa ya fara shan metformin. Zai iya yiwuwa daga nan da nan za a iya gano cutar sankarar mama, wani ɓangare mai mahimmanci na marasa lafiya suna zuwa likita lokacin da lafiyar su ta yi rauni sosai. Tuni a cikin shekaru 5 na farko na cututtukan ƙwayar cuta na lalacewa, ana rage ayyukan ayyukan sel da ke samar da insulin. A wannan lokacin, metformin da abinci mai yiwuwa ba su isa ba, kuma an tsara wa marasa lafiya magunguna waɗanda ke haɓaka kira da sakin insulin. Glyclazide MV shima yana cikin irin waɗannan magunguna.
Yaya maganin yake aiki?
Dukkanin gliclazide da aka samu a cikin narkewa shine yake shiga cikin jini to akwai ɗaukar nauyin protein. A yadda aka saba, glucose ya shiga cikin sel na beta kuma yana ƙarfafa masu karɓa na musamman waɗanda ke haifar da sakin insulin. Glyclazide yana aiki da wannan ka'ida, yana haifar da tsohuwar hanyar jigilar kwayoyin.
Sakamakon samar da insulin bai iyakance ga aikin MV Glyclazide ba. Magungunan zai iya:
- Rage juriya insulin. Mafi kyawun sakamako (ƙwarewar insulin da kashi 35%) ana lura dashi a cikin ƙwayar tsoka.
- Rage haduwar glucose ta hanta, ta yadda zai dace da tsarin azumi.
- Ta hana jini kwance.
- Imarfafa aikin sinadarin nitric oxide, wanda ya shiga cikin daidaita matsin lamba, rage kumburi, da inganta haɓaka jini zuwa gaɓar sel.
- Yi aiki azaman maganin antioxidant.
Fitar saki da sashi
A cikin kwamfutar hannu Gliclazide MV shine 30 ko 60 MG na kayan aiki. Abubuwa masu taimako sune: cellulose, wanda aka yi amfani dashi azaman wakilin bulking, silica da magnesium stearate kamar emulsifiers. Allunan fararen launi ko launi mai tsami, an sanya su cikin blisters na 10-30. A cikin fakitin 2-3 na blisters (30 ko allunan 30 ko 60) da umarnin. Za'a iya raba Gliclazide MV 60 MG cikin rabi, don wannan akwai haɗari akan allunan.
Ya kamata a bugu da magani a lokacin karin kumallo. Gliclazide yana aiki ba tare da la'akari da kasancewar sukari a cikin jini ba. Don haka cewa rashin jini a cikin jiki ba ya faruwa, babu abincin da ya kamata a tsallake, kowannensu ya yi daidai adadin carbohydrates. A bu mai kyau ku ci har sau 6 a rana.
Dokokin zaɓi na sashi:
Canji daga Gliclazide na yau da kullun. | Idan mai ciwon sukari ya ɗauka a baya wanda ba a tsawaita ba, ana iya tunawa da kashi ɗaya na maganin: Gliclazide 80 daidai yake da GLlazide MV 30 MG a allunan. |
Fara amfani, idan an wajabta maganin a karon farko. | 30 MG Duk masu ciwon sukari suna farawa tare da shi, ba tare da la'akari da shekaru da glycemia ba. Gaba daya watan mai zuwa, haramun ne a kara sashi domin a baiwa mutum lokacinda ya zama sabon yanayin aiki. An keɓe wani banbanci kawai ga masu ciwon sukari masu fama da sukari mai yawa, suna iya fara haɓaka kashi bayan makonni 2. |
The odan kara sashi. | Idan 30 MG bai isa ba don rama don ciwon sukari, kashi na miyagun ƙwayoyi yana ƙaruwa zuwa 60 MG da ƙari. Kowane sashi na ƙaruwa ya kamata ya zama aƙalla makonni 2 bayan haka. |
Matsakaicin sashi. | 2 shafin. Gliclazide MV 60 MG ko 4 zuwa 30 MG. Kar ku zarce ta kowane irin hali. Idan bai isa ba don sukari na al'ada, ana ƙara wasu masu maganin antidiabet a cikin magani. Umarni yana ba ku damar haɗuwa da gliclazide tare da metformin, glitazones, acarbose, insulin. |
Matsakaicin adadin a babban haɗarin hypoglycemia. | 30 MG Theungiyar haɗarin ta haɗa da marasa lafiya da cututtukan endocrine da cututtukan zuciya, da kuma mutanen da ke ɗaukar glucocorticoids na dogon lokaci. Glyclazide MV 30 MG a allunan an fi son su. |
Cikakkun umarnin don amfani
Dangane da shawarwarin asibiti na Ma'aikatar Lafiya ta Tarayyar Rasha, ya kamata a rubanya gliclazide don haɓaka ƙwayar insulin. A ma'ana, yakamata a tabbatar da rashin lafiyar kwayar halitta ta hanyar binciken mai haƙuri. Dangane da sake dubawa, wannan ba koyaushe bane yake faruwa. Likitocin kwantar da hankali da kuma endocrinologists suna ba da magani ne "ta ido". A sakamakon haka, fiye da adadin insulin da ake buƙata yana ɓoye, mai haƙuri koyaushe yana son cin abinci, nauyinsa yana ƙaruwa a hankali, kuma biyan diyya don ciwon sukari bai isa ba. Bugu da ƙari, ƙwayoyin beta tare da wannan yanayin aiki suna lalata da sauri, wanda ke nufin cewa cutar ta tafi mataki na gaba.
Yadda za a guji irin wannan sakamako:
- Fara tsananin riko da abinci ga masu ciwon sukari (tebur mai lamba 9, adadin da aka ba da izinin carbohydrates yana ƙaddara ta likita ko mai haƙuri da kansa bisa ga glycemia).
- Introduaddamar da motsi mai aiki a cikin ayyukan yau da kullun.
- Rasa nauyi zuwa al'ada. Yawan mai mai wuce gona da iri yana cutar da ciwon suga.
- Sha glucophage ko misalinsa. Mafi kyawun kashi shine 2000 MG.
Kuma kawai idan waɗannan matakan basu isa sukari na al'ada ba, zaku iya tunani game da gliclazide. Kafin fara magani, yana da kyau a ɗauki gwaje-gwaje don C-peptide ko insulin don tabbatar da cewa ƙwayar hormone ba ta da kyau.
Lokacin da glycated haemoglobin ya fi 8.5%, MV Gliclazide za'a iya ba shi tare da abinci da metformin na ɗan lokaci, har sai an biya dila. Bayan wannan, batun cire magunguna an yanke hukunci daban-daban.
Yadda ake ɗauka yayin daukar ciki
Umarnin don amfani da shi ya hana magani tare da Gliclazide yayin daukar ciki da kuma lactation. Dangane da rarrabuwar FDA, maganin yana cikin aji na C. Wannan yana nufin yana iya yin illa ga ci gaban tayin, amma baya haifar da alamun haihuwa. Glyclazide ya aminta da maye gurbin tare da maganin insulin kafin daukar ciki, a cikin matsanancin yanayi - a farkon sosai.
Ba a gwada yiwuwar shayarwa tare da gliclazide ba. Akwai tabbaci cewa shirye-shiryen sulfonylurea na iya wucewa cikin madara kuma suna haifar da ƙin jini a cikin jarirai, don haka an haramta yin amfani da su a wannan lokacin.
Side effects da yawan abin sama da ya kamata
Mafi mummunar sakamako na Gliclazide MV shine hypoglycemia. Yana faruwa lokacin da samar da insulin ya wuce buƙatar shi. Dalilin na iya zama haɗuwa da ƙwayar cuta mai haɗari, tsallake abinci ko karancin carbohydrates a ciki, har ma da yawan motsa jiki. Hakanan, raguwa cikin sukari na iya haifar da tarin gliclazide a cikin jini sakamakon cutar koda da kuma hanta, haɓaka ayyukan insulin a cikin wasu cututtukan endocrine. Dangane da sake dubawa, a cikin lura da sulfonylureas tare da hypoglycemia, kusan dukkanin masu ciwon sukari suna fuskanta. Yawancin saukad da sukari za a iya kawar da su a mataki mai sauƙi.
A matsayinka na mai mulkin, hypoglycemia yana tare da alamomin halayyar: yunwar mai ƙarfi, girgiza daga ƙarshen, tashin hankali, rauni. Wasu marasa lafiya sannu a hankali sun daina jin alamun waɗannan alamun, raguwar sukarin su na cikin barazanar rayuwa. Suna buƙatar sarrafa glucose akai-akai, ciki har da dare, ko canja wuri zuwa wasu allunan rage sukari waɗanda basu da irin wannan sakamako.
Rashin haɗarin wasu ayyukan da ba a buƙata na Gliclazide an kimanta su a matsayin mafi wuya kuma ba kasada ba. Matsaloli da ka iya:
- matsalolin narkewa a cikin nau'in tashin zuciya, motsi mai wuya, ko zawo. Kuna iya kawar da su ta hanyar shan Glyclazide yayin cin abinci mai yawan wuta;
- rashin lafiyan fata, yawanci a nau'in huhu, tare da itching;
- raguwa a cikin platelet, sel jini, farin sel. Abun da ke cikin jini ya koma daidai bisa ga kansa bayan shafewar Gliclazide;
- ƙara haɓaka na ɗan lokaci a cikin aikin hanta enzymes.
Ga wanda Glyclazide MV ya saba wa doka
Contraindications bisa ga umarnin | Dalilin ban |
Hypersensitivity to gliclazide, analogues, sauran shirye-shiryen sulfonylurea. | Babban yiwuwar halayen anaphylactic. |
Nau'in 1 na ciwon sukari, kwantar da hanji. | Idan babu ƙwayoyin beta, aikin insulin ba zai yiwu ba. |
Mai tsananin ketoacidosis, cutar sikila. | Marasa lafiya na bukatar taimakon gaggawa. Harkokin insulin ne kawai zai iya ba da shi. |
Renal, gazawar hanta. | Babban haɗarin hauhawar jini. |
Jiyya tare da miconazole, phenylbutazone. | |
Amfani da barasa | |
Ciki, HB, shekarun yara. | Rashin ingantaccen bincike. |
Me za a iya maye gurbinsa
Gliclazide na Rasha ba shi da tsada, amma maimakon magani mai inganci, farashin kayan kwalliyar Gliclazide MV (30 MG, raka'a 60) ya kai 150 rubles. Sauya shi da analogues ne kawai idan ba a sayar da allunan da aka saba ba.
Magunguna na asali shine Diabeton MV, duk wasu magunguna masu daidaitaccen tsari, glilazide MV sune kwayoyin, ko kwafe. Farashin Diabeton ya kusan sau 2-3 sau da yawa kamar yadda yake yi.
Gliclazide MV analogues da kuma waɗanda suka yi rajista a cikin Federationungiyar Tarayyar Rasha (kawai shirye-shiryen sakewa masu sassauci suna nuna):
- Glyclazide-SZ wanda Severnaya Zvezda CJSC ya samar;
- Golda MV, Pharmasintez-Tyumen;
- Glyclazide Canon daga Canonpharm Production;
- Gliclazide MV Pharmstandard, Pharmstandard-Tomskkhimfarm;
- Diabetalong, mai samar da MS-Vita;
- Gliclada, Krka;
- Glidiab MV daga Akrikhin;
- Kamfanin samar da magunguna na Diabefarm MV.
Farashin analogues shine 120-150 rubles a kowane kunshin. Gliklada da aka yi a Slovenia shine magani mafi tsada daga wannan jerin, farashin shirya kusan 250 rubles.
Nazarin masu ciwon sukari
Na karanta cewa Galvus yana bada sakamako iri ɗaya, amma yana da aminci sosai dangane da faɗuwar sukari mai kaifi. Zan tambayi likita don maye gurbin su da Gliclazide.