Insulin Rinsulin: aiki, koyarwa, farashi

Yanzu zaɓin hanyar da za a rama masu ciwon sukari ya bazu: a nan akwai injinan halittar jini da ƙarin insulins na zamani. Rinsulin shine kawai magani na gida wanda ya sami nasarar daukar nauyin (fiye da 10%) na kasuwar insulin a Rasha.

Haɓaka abu da fasaha ta asali, keɓantaccen taro tun daga 2004, Geropharm ne ya gudanar da shi. Akwai Rinsulin a cikin nau'ikan 2 - Rinsulin P da Rinsulin NPH na gajere, kuma lispro da glargine insulin suna a mataki na gwaji na asibiti. An tabbatar da ingancin abu ɗin ta hanyar wasu ɗakunan bincike na Turai masu zaman kansu da yawa. A cewar su, ingancin magungunan mu ba shi da matsala fiye da analog ɗin da aka shigo da su tare da wannan abun da ke ciki.

Rinsulin P - bayanin da kuma sakin siffofin

Da ke ƙasa akwai wasu bayanai game da maganin da zai ba da hoto gaba ɗaya na insulin.

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

Aiki

Rinsulin P yana haɗuwa da sauri cikin jini daga ƙwayar subcutaneous, tasirin hypoglycemic yana farawa bayan rabin sa'a. Kwayar halittar ta danganta ga masu karɓar sel, waɗanda ke ba da izinin jigilar glucose daga tasoshin jini zuwa kyallen. Rarfin Rinsulin don kunna glycogen samuwar da rage ƙimar glucose na hanta shima yana shafar raguwar glycemia.

Tasirin miyagun ƙwayoyi ya dogara da yawan ƙwaƙwalwa, kuma wannan, bi da bi, akan kauri da wadatar jini na kashin da ke cikin ƙananan allurar. A matsakaici, magunguna na Rinsulin P sun yi kama da sauran gajerun insulins:

• lokacin farawa shine minti 30
• ganiya - kimanin awa 2
• babban aikin shine awa 5,
• jimlar lokacin aiki - har zuwa 8 hours.

Zaka iya hanzarta aikin insulin ta hanyar allura dashi cikin ciki ko babba, kuma ka rage shi ta hanyar allura da shi a gaban cinya.

Don ramawa game da ciwon sukari na mellitus akan Rinsulin, mai haƙuri dole ne ya bi abinci sau 6 a rana, yakamata tsaka-tsakin tsakanin manyan abinci 3 ya zama 5 awanni, tsakanin su sau 10-20 g na jinkirin carbohydrates ana buƙatar.

Abun ciki

Rinsulin P ya ƙunshi kayan aiki guda ɗaya kaɗai - insulin mutum. An yi ta ne ta hanyar maimaitawa, wato, ta amfani da kwayar halittar da aka gyara ta. Yawancin lokaci ana amfani da E. coli ko yisti don waɗannan dalilai. A cikin tsari da tsari, wannan insulin din bashi da banbanci daga kwayar halittar da sinadarin dake motsa jini.

Akwai ƙananan abubuwan taimako a Rinsulin P fiye da yadda ake shigo da analogues. Bugu da ƙari ga insulin, ya ƙunshi ruwa kawai, metacresol mai kiyayewa da glycerol mai ƙarfi. A gefe guda, saboda wannan, yiwuwar rashin lafiyan halayen a wurin allurar yana da ƙasa. A gefe guda, ɗauka cikin jini da kuma ragewar sukari na Rinsulin na iya zama ɗan ɗan bambanci. Saboda haka, sauya sheka zuwa wani magani tare da kayan aiki iri ɗaya na iya ɗaukar kwanaki da yawa, lokacin biyan diyyar ciwon sukari mellitus yayi rauni.

Sakin Fom

Rinsulin P shine mafita mara launi, cikakkiyar bayani, a cikin milliliter na 100 raka'oin.

Siffofin Saki:

1. Vials tare da maganin 10 ml, magani daga gare su dole ne a allura tare da sirinji na insulin.
2. 3 mlm katiri. Ana iya sanya su a cikin kowane alkawuran sirinji da aka tsara don daidaitaccen katun: HumaPen, BiomaticPen, Autopen Classic. Don samun damar shiga ainihin yawan insulin, ya kamata a ba wa fifiko alkalami tare da ƙaramin adadin ƙaruwa. Misali, HumaPen Luxura yana ba ku damar gwada raka'a 0.5.
3. Abin da za'a iya zubar da alkalami na Rinastra 3 ml. Sauya katun a cikinsu ba zai yuwu ba, mataki na 1.

Umarnin don amfani da Rinsulin

Matsaloli marasa yiwuwa

Mitar sakamako na sakamako na Rinsulin yana da ƙasa da yawa, yawancin marasa lafiya kawai suna fuskantar matsalar rashin ƙarfi na hypoglycemia.

Jerin yiwuwar tasirin da ba'a so ba bisa ga umarnin:

1. Hypoglycemia yana yiwuwa idan aka lasafta yawan magungunan ba daidai ba kuma ya wuce buƙatun ilimin halayyar da ake kira hormone. Rashin bin umarni don amfani kuma na iya haifar da raguwar sukari: dabarar allurar rashin inganci (insulin ta shiga cikin tsoka), dumama wurin allurar (zazzabi mai iska, damfara, gogayya), kuskuren sirinji mai kuskure, aikin motsa jiki mara ƙima. Dole ne a kawar da cututtukan jini a lokacin da alamun farko suka bayyana: zazzaɓi, girgiza, yunwar, ciwon kai. Yawancin lokaci 10-15 g na carbohydrates mai sauri sun isa ga wannan: sukari, syrup, Allunan glucose. Mai tsananin hypoglycemia na iya haifar da lalacewa ta hanyar tsarin juyayi, yana haifar da coma.
2. Na biyu mafi yawan sakamako masu illa shine rashin lafiyan halayen. Mafi sau da yawa, ana bayyana su a cikin rauni ko ja a wurin allura kuma sun ɓace makonni biyu bayan alƙawarin maganin insulin. Idan itching ta kasance, za a iya shan maganin rigakafi. Idan rashin lafiyan ya juya ya zama babban tsari, cutar urticaria ko ta Quincke ta faru, dole ne a maye gurbin Rinsulin R.
3. Idan mai ciwon sukari ya kamu da cutar rashin jini a jiki na dogon lokaci, ana kirga kashi na farko na insulin ta yadda sukari jini ya ragu sosai, sama da wata daya. Tare da raguwa mai yawa a cikin glucose zuwa al'ada, lalacewa ta ɗan lokaci a cikin ƙoshin lafiya mai yiwuwa ne: wahayi mai gani, kumburi, jin zafi a cikin gabobin - yadda ake lissafin yawan insulin.

Abubuwa da yawa suna yin tasiri akan aikin insulin, saboda haka marasa lafiya masu ciwon sukari a kan ilimin insulin ya kamata su haɗa kai tare da likita duk magunguna, magungunan jama'a da kayan abinci wanda suke shirin amfani da su.

Umarni yana ba da shawara don kulawa da kulawa ta musamman ga waɗannan rukunin magunguna masu zuwa:

• magungunan hormonal: hana haihuwa, hormones thyroid, glucocorticosteroids;
• magunguna don hauhawar jini: diuretics na rukuni na thiazide, duk magunguna suna ƙarewa a -pril da -sartan, lazartan;
• bitamin B3;
• shirye-shiryen lithium;
• hanyoyin tetracyclines;
• kowane jami'in hypoglycemic;
• acetylsalicylic acid;
• wasu maganin cututtukan fata.

Sakamakon ciwon sukari na mellitus ya lalace kuma duk kwayoyi da abubuwan sha da ke ɗauke da giya na iya haifar da matsanancin rashin ƙarfi na jini - duba abin da ke lalata cututtukan ƙwayar cuta. Magungunan Beta-blocker da aka yi amfani da su don cututtukan zuciya suna rage alamun hypoglycemia kuma suna hana shi ganowa akan lokaci.

Siffofin aikace-aikace

Bayan ƙarshen aiki, an lalata insulin a cikin hanta da ƙodan. Idan mai ciwon sukari yana da cututtuka na ɗayan waɗannan gabobin, sashi na Rinsulin na iya buƙatar gyara. Ana buƙatar karuwar insulin a lokutan canje-canje na hormonal, tare da cututtuka masu kamuwa da cuta, zazzabi, rauni, damuwa, rashin ƙarfi. Yawan maganin yana iya zama ba daidai ba idan mai ciwon sukari ya yi amai, zawo, da kumburi a cikin narkewa.

Shahararrun analogues na Rinsulin R sune Danish Actrapid da Regular Amurka Humulin. Bayanan bincike sun nuna cewa ingancin alamun Rinsulin suna a matakin ka'idodin Turai.

Idan m alerji ya faru, Rinsulin dole ne a watsar da. Yawancin lokaci, sauran insulins suna haifar da irin wannan amsawa, don haka suna amfani da hanyar ultrashort - Humalog ko NovoRapid.

Farashin Rinsulin P - daga 400 rubles. kowace kwalba har zuwa 1150 don alkalami 5.

Bambanci tsakanin Rinsulin P da NPH

Rinsulin NPH magani ne na yau da kullun na masana'anta guda ɗaya. Dangane da umarnin, ana amfani dashi don daidaita sukari mai azumi. Rinsulin NPH yana da tsari guda na aiki, sakin saki, alamomi masu kama da juna, contraindications da sakamako masu illa kamar Rinsulin R. A matsayinka na doka, tare da maganin insulin duka nau'ikan insulin an haɗa su - gajere da matsakaici. Idan har an kiyaye sirrin kwayoyin halittun ku (wani nau'in 2 da ciwon suga na ciki), zaku iya amfani da magani ɗaya kawai.

Fasali na Rinsulin NPH:

Farashin kwalban Rinsulin NPH ~ 400 rubles., Karancin katako ~ 1000 rubles., Alƙaluman sikari guda biyar ~ 1200 rubles.