Isofan insulin (Injiniyan ɗan adam)

Tare da ciwon sukari, nan ba da jimawa ba, rashi na insulin da aka fitar da hanji ya fara ji, karancinsa ya kasance ta hanyar maganin hormone, wanda aka allura.

Isofan insulin shine ɗayan abubuwan da ake amfani da su don sauya magani. A cikin jikin, wannan insulin yana aiki kamar na halitta: yana tura wuce haddi glucose ga nama, inda ya rushe, yana samar da jiki da makamashi. Tare da nau'in ciwon sukari na 1, Isofan koyaushe yana haɗe tare da hormone mai gajeren lokaci, wanda aka tsara don sarrafa glandonmia na postprandial (bayan cin abinci). A cikin nau'in cuta ta 2, insulin Isofan kawai zai iya isa ga masu ciwon sukari.

Abun da magani

Insulin da aka yi amfani da shi a cikin ciwon sukari ya kasu kashi da yawa cikin manyan rukuni gwargwadon lokacin aiki. Don cikakken kwaikwayon sirrinku na insulin, kuna buƙatar hormone mai nau'ikan biyu: tsayi (ko matsakaici) da gajeru (ko ultrashort) - labarin akan nau'in insulin. An rarraba Isofan a matsayin insulin na matsakaici. Tare da yin amfani da ninki biyu a rana, yana da ikon samar da ƙarancin matakan hormone a cikin jini, wanda ke rage glucose, wanda ke shiga cikin jini daga hanta a kusa da agogo.

Isofan insulin ya ƙunshi kayan aiki guda 2:

1. Insulin. A da, anyi amfani da hodar iblis da bovine, yanzu ana amfani da injiniyan ɗan adam ne kawai, wanda yayi daidai da hormone wanda ƙwaƙwalwar mutum ke samarwa. Ana yin ta ta amfani da ƙwayoyin cuta wanda aka gyara, ƙwayar tana da babban darajar tsarkakewa, jiki yana iya sauƙin sa kuma yana da sauƙin haifar da rashin lafiyan cuta fiye da magabata.
2. Protamine - wani furotin da ake amfani dashi azaman aikin insulin. Godiya gareshi, lokacin horon daga cikin kwayar subcutaneous zuwa cikin tasoshin ya karu daga 6 zuwa 12 hours. A cikin insulin, hormone Isofan da protamine suna hade cikin adadin isophane, wato, babu wuce haddi na abubuwan da ke cikin maganin. Da sunan mahaliccinsa, masanin kimiyyar Denmark Hagedorn, ana kiran insulin Isofan a cikin littattafan likitanci azaman tsattsauran protamine Hagedorn, ko NPH-insulin.

Saboda haka protamine tare da insulin na iya ƙirƙirar lu'ulu'u, an ƙara zinc a cikin mafita. Phenol da m-cresol suna ƙunshe a cikin shirye-shiryen azaman abin kiyayewa; don samun mafita tare da ruwan tsaka-tsaki, ana amfani da acid mai rauni ko tushe. Don analogues na samfuran daban-daban, abun da ke ciki na kayan taimako sun bambanta, an ba da cikakken jerin abubuwa a cikin umarnin don amfani.

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

Alamu don alƙawari

Dalilin da ya sa bashin insulin wucin gadi na iya zama:

1. 1 nau'in kamuwa da cutar siga. Ana amfani da tsari mai ƙarfi na ilimin insulin, wato, ana amfani da Isofan da gajere insulin.
2. Wasu nau'ikan kamuwa da cutar sankarau.
3. Nau'i na 2, idan allunan rigakafin kwakwalwa na hana karuwa ko kuma basu bayar da isasshen ikon kula da ciwon suga. A matsayinka na mai mulkin, an fara amfani da ilimin insulin tare da Isofan. Bukatar gajeren hormone ya bayyana daga baya.
4. Nau'i na 2 yayin daukar ciki.
5. A matsayin maye ga allunan, idan nau'in ciwon sukari na 2 yana cikin matakin lalata. Bayan raguwar sukari, za a iya canja wurin mai haƙuri zuwa shirye-shiryen bakin.
6. Ciwon suga, idan abinci na musamman baya rage sukari zuwa al'ada.

Alamar kasuwanci

Isofan Insulin shine mafi mashahuri insulin basal a duniya. Drugsarin magunguna na zamani sun fi tsada yawa kuma sun fara cinye kasuwar. Sunayen Isofan sunaye masu rijista a cikin Federationungiyar Rasha:

Dukkanin magungunan da ke sama sune analogues. Suna da hankali iri ɗaya kuma suna da kusanci da ƙarfi, sabili da haka, tare da ciwon sukari, yana yiwuwa a canza daga wannan magani zuwa wani ba tare da daidaitawa ba.

Ka'idojin aiki

Isofan insulin yana da tasirin hypoglycemic. Sannu a hankali yana shiga cikin jini daga kasusuwa na ciki, kwayar ta bazu cikin jiki kuma ta kasance ta sadu da masu karɓar insulin waɗanda ke kan bangon tantanin. Sakamakon wannan, membranes ya zama mai dacewa ga glucose, kuma yana iya shiga cikin tantanin halitta, inda ya lalata tare da sakin kuzari. Jinin jini, bi da bi, yana raguwa.

Insulin kuma yana ba da gudummawa ga samar da glycogen a cikin tsokoki da hanta, wanda aka samo daga glucose kuma wani nau'in tanadin makamashi ne na jiki. Ana amfani da wannan ajiyar lokacin da sukari jini yayi ƙasa.

Wani muhimmin aikin insulin shine don hana fashewa da haɓakar furotin da ƙwayar carbohydrate.

Tsawon lokacin allura ɗaya yasha bamban sosai a cikin mutane daban-daban. Ya dogara da wuri da zurfin allura, matakin samar da jini ga wannan yanki, kashi, nau'in ciwon sukari, yawan zafin jiki da sauran abubuwan.

Bayanin aikin insulin na Isofan, bayanan da aka killace daga umarnin don amfani:

Yana rushe insulin tare da enzymes na musamman, yayin da aka kirkiro metabolites, ba shi da tasirin sukari. Kashe rabin rayuwa ya bambanta tsakanin awanni 5-10.

Sakamakon Gina na Isofan Insulin

Sakamakon insulin yana da tasiri sosai ga abubuwan muhalli. Idan ana yin insulin da yawa fiye da yadda jiki ke buƙata, masu ciwon sukari suna haɓaka ƙoshin jini. Zasu iya haifar da hakan:

1. Azumi, tsallake abinci - kalli labarin game da azumi don kamuwa da cutar siga.
2. Rashin narkewar narkewa wanda ke haifar da ɗaukar glucose: amai, zawo.
3. Ci gaba da aiki a jiki.
4. Haɓakawa tare da magungunan antidiabetic.
5. Cututtukan Endocrine.
6. Cutar cututtuka mai mahimmanci na gabobin da ke cikin metabolism na hanta: hanta da koda.
7. Canza wurin allurar, zahirin (shafawa, tausa) ko zazzabi (sauna, pad ɗin dumama) tasiri akan sa.
8. Ba daidai ba dabara dabara.
9. Kwayoyin da ke inganta tasirin insulin. Magungunan Hormonal da diuretic suna da babban sakamako.
10. Barasa da nicotine.

Tare da sukari na saukar da tsarin gaggawa, duk masu ciwon sukari ta amfani da insulin aka gabatar dasu. Ya ƙunshi ciwan carbohydrates mai sauri, a cikin manyan lokuta - allura na 1 mg na glucagon, dropper tare da glucose - ƙarin akan abin da za a yi idan sukari jini ya ragu sosai.

Commonlyarancin yau da kullun, marasa lafiya masu ciwon sukari mellitus sun sami gogewar lipodystrophy (canje-canje na dystrophic a cikin maɓallin subcutaneous a wuraren allura akai-akai) da kuma maganganun tashin hankali a cikin nau'in edema, fitsari, da redness.

Dokokin gabatarwar

Adadin Isofan aka zaɓi da farko, ga gajeriyar insulin. Yana da guda ɗaya ga kowane masu ciwon sukari. Kimanin jimlar buƙatar homon a cikin rashi na mutum shine raka'a 0.3-1 a kowace kilo 1 na nauyi, Isofan yana lissafin 1/3 zuwa 1/2 na buƙatar. Ana buƙatar ƙarancin insulin don kamuwa da cututtukan type 2, ƙari - don marasa lafiya masu kiba da juriya insulin. Siffofin abinci mai gina jiki ba shi da tasiri sosai a kan maganin Isofan, tun da ɗan gajeren insulin yana ba da taimako don rama cutar ƙwayar cuta ta prandial.

Yadda za a magance Isofan:

1. Umarni yana ba da shawarar gudanar da maganin kawai. Don hana mafita daga shiga cikin tsoka, kuna buƙatar zaɓar madaidaicin allura mai dacewa. An hana gudanar da aiki cikin jini
2. Don gudanarwa, ana iya amfani da sirinji insulin da ƙarin alkairin zamani. Ba za a iya amfani da insulin na matsakaici a cikin farashinsa ba.
3. Isofan insulin dakatarwa ce, don haka tsari mai lalacewa ya cika a lokaci a kasan vial. Kafin yin allura, dole ne a gauraya ƙwayar da kyau. Idan ba zai yiwu a cimma daidaiton launi na dakatarwa ba, insulin ya lalace, kuma baza a iya amfani dashi ba.
4. Mafi kyawun wurin allurar shine cinya. Hakanan an ba shi izinin yin allura a cikin ciki, gindi, kafada - yadda ake allurar insulin daidai.
5. Yi sabon allura aƙalla 2 cm daga wacce ta gabata. Zaku iya tsayawa a wuri guda bayan kwana 3.

Amfani da juna biyu

Ana iya amfani da Isofan yayin daukar ciki da HB, tunda ba ya ratsa jinin yarinyar ta cikin mahaifa da madara. A cikin matan da ke da ciwon sukari waɗanda ke da jarirai, maganin insulin shine kawai hanyar da za a rage glycemia da aka yarda a Rasha.

Bukatar maganin na watanni 9 sau da yawa yana canzawa lokaci guda tare da canji a cikin yanayin hormonal na mace, don haka dole ne a kai a kai don daidaita sashin insulin. Controluntataccen sarrafa sukari a lokacin daukar ciki sharudda ne don rigakafin fetopathy, lalata, mutuwar tayi.