Basal, ko kuma kamar yadda ake kiran su, insulins na baya suna taka muhimmiyar rawa a lura da ciwon sukari. Suna taimakawa kiyaye matakan sukari na jini tsakanin abinci, suna haɓaka shan glycogen da ke cikin ƙwayoyin hanta.
Zuwa yau, an inganta abubuwan dindindin na basal na zamani, tsawon lokacin da zai iya wuce sama da awanni 42.
Ofaya daga cikin waɗannan magungunan shine Ryzodeg, sabon insulin aiki na dogon lokaci.
Abun ciki da kaddarorin
Ryzodeg shine sabon ƙarni na insulin basal wanda za'a iya amfani dashi cikin nasara don magance nau'in 1 da nau'in ciwon sukari na 2. Rashin daidaituwa na Ryzodega ya ta'allaka ne akan cewa a lokaci guda ya kunshi insulin-gajere-insulin aikin insulin da insulin na aikin-tsawan tsawa tsawan degludec.
Dukkanin insulins da aka yi amfani dasu don ƙirƙirar shirye-shiryen Ryzodeg sune analogues na insulin mutum. Ana samun su ta hanyar kimiyyar halittar halittar DNA ta amfani da yeast ungiel fungi na halittar Saccharomyces cerevisiae.
Saboda wannan, suna ɗaure sauƙin zuwa mai karɓar insulin nasu na mutum kuma, yayin ma'amala da shi, yana ba da gudummawa ga ingantaccen ƙwayar glucose. Saboda haka, Ryzodegum yana aiki cikakke azaman insulin insulin.
Ryzodeg yana da tasirin sakamako biyu: a hannu ɗaya, yana taimaka wa ƙusoshin cikin gida don mafi kyawun ɗaukar sukari daga jini, kuma a ɗayan, yana rage mahimmancin samar da glycogen ta ƙwayoyin hanta. Wadannan kaddarorin suna sanya Ryzodeg daya daga cikin ingantaccen insulin basal mai aiki.
Insulin degludec, wanda shine ɗayan kayan haɗin Ryzodeg, yana da ƙarin aiki mai tsayi. Bayan gabatarwa cikin ƙwayar subcutaneous, yana sannu a hankali kuma ya ci gaba da shiga cikin jini, wanda ya ba mai haƙuri damar hana haɓakar sukari na jini sama da matakin al'ada.
Don haka, Ryzodegum yana da tasirin sakamako na hypoglycemic, duk da haɗuwar degludec tare da kewayawa. Wadannan abubuwa biyu suna kama da insulin tasiri a cikin wannan ƙwayar cuta suna haifar da ingantaccen haɗin haɗin gwiwa wanda tsawon insulin baya hana ɗaukar gajere.
Wannan aiki na tashi yana farawa ne bayan allurar Ryzodegum. Yana cikin sauri yana shiga cikin jinin mai haƙuri kuma yana taimakawa sosai don rage matakan sukarin jini.
Furtherarin gaba, degludec yana fara tasiri a jikin mai haƙuri, wanda ke ɗaukar hankali a hankali kuma yana haɗuwa da cikakkiyar haƙuri na buƙatar basal insulin na tsawon awanni 24.
Umarnin don amfani da miyagun ƙwayoyi
Ya kamata a gudanar da Rysodeg cikin ƙwayar subcutaneous, in ba haka ba mai haƙuri na iya haɓaka sakamako masu haɗari waɗanda ke buƙatar kulawar likita na gaggawa.
Yin allura tare da Ryzodegum ya zama dole sau 1 ko 2 a rana kafin karin kumallo, abincin dare ko abincin rana. Idan ana so, mai haƙuri zai iya canza lokacin allura da kansa, amma idan har magungunan sun shiga jikin mutum kafin babban abinci.
A cikin lura da marasa lafiya da aka gano tare da nau'in mellitus na sukari na 2, ana iya amfani da shirye-shiryen Ryzodeg duka a matsayin babban wakili na warkewa kuma a haɗe tare da allunan rage sukari ko insulins na gajeran lokaci.
A cikin maganin warkewa don marasa lafiya da ke fama da nau'in 1 mellitus na ciwon sukari, ana amfani da Ryzodeg a cikin haɗin gwiwa tare da shirye-shiryen insulin gajere ko ultrashort. Ga wannan rukuni na marasa lafiya, yana da mahimmanci don gudanar da maganin kafin cin abinci, kuma ba bayan.
Ya kamata a zaba magungunan Ryzodeg gaba ɗaya, yin la'akari da yanayin mai haƙuri da buƙatunsa. Eterayyade daidai adadin insulin basal zai taimaka wajen auna matakan sukari na yau da kullun. Idan ya yawaita, to satin yana buƙatar gyara nan da nan.
Bugu da ƙari, ana iya buƙatar daidaitawa yayin canza abincin mai haƙuri ko aikin jiki. Hakanan, yawan shan magunguna sau da yawa yana shafar matakin sukari na jini, wanda na iya buƙatar haɓaka kashi na Rysodeg.
Yadda za a zabi sashin insulin basal Ryzodeg:
- Type 1 ciwon sukari. Tare da wannan cutar, sashi na Ryzodeg ya kamata ya zama kusan 65% na yawan haƙuri na yau da kullun yana buƙatar insulin. Wajibi ne a gudanar da maganin sau 1 kowace rana kafin abinci a hade tare da insulin gajere. Idan ya cancanta, ya kamata a daidaita yawan adadin insulin basal;
- Type 2 ciwon sukari. Ga marasa lafiya da wannan nau'in cutar, azaman farkon maganin yau da kullun, ana bada shawarar shigar da raka'a 10 na Ryzodeg kowace rana. Hakanan za'a iya canza wannan kashi gwargwadon bukatun mutum na mai haƙuri.
Yadda ake amfani da Ryzodeg:
- Basal insulin Risodeg an yi shi ne musamman don gudanar da subcutaneous. Wannan magani bai dace da allura ta ciki ba, saboda zai iya haifar da mummunan harin na hypoglycemia;
- Bai kamata a sha magungunan Ryzodeg ba har abada, saboda a wannan yanayin shan insulin cikin jini zai haɓaka sosai;
- Ryzodeg ba ayi nufin amfani dashi a cikin famfon inulin ba;
- Ya kamata a yi allurar insulin Rizodeg a cinya ko cincin ciki, wani lokacin ana barin shi ya sanya allura a hannu;
- Bayan kowace allura, ya kamata a canza wurin allurar don kada lipodystrophy ya faru a cikin ciwon sukari na mellitus.
Ana iya amfani da magani Ryzodeg don magance marasa lafiya a cikin rukuni na musamman, wato sama da shekaru 65 ko fama da raunin koda ko gazawar hanta. Koyaya, a wannan yanayin, yakamata ku lura da matakin glucose a cikin jini kuma, idan ya cancanta, daidaita sashi na insulin.
Wannan insulin na basal ana iya amfani dashi da sharadin gwargwadon amfani da magani na cututtukan siga a yara da matasa masu shekaru 18 da haihuwa.
Amma babu wani binciken da ya tabbatar da amincin Ryzodegum ga marasa lafiyar yara.
Farashin miyagun ƙwayoyi
Kudin insulin basal Ryzodeg ya dogara da irin maganin. Don haka ana iya siyan katako na gilashin 3 ml (300 PIECES) a farashin 8150 zuwa 9050 rubles. Koyaya, a wasu kantin magunguna ana bayar da wannan magani a farashi mai girma, sama da 13,000 rubles.
Farashin alkairin sirinji ya fi kwanciyar hankali kuma, a matsayinka na mai mulki, ya kama daga 6150 zuwa 6400 rubles. A cikin lokuta masu wuya, zai iya kaiwa 7000 rubles.
Kudin magungunan Ryzodega kusan iri ɗaya ne a duk yankuna na Rasha. Koyaya, magani ne mai wuya a cikin ƙasarmu, don haka ba za a iya siye shi ba a dukkanin kantin magunguna na Rasha.
Sau da yawa, waɗanda suke so su sayi Ryzodeg dole ne suyi wannan littafin a cikin kantin magani, saboda duk da hauhawar farashi, masu haƙuri suna kamuwa da ita cikin sauri. Wannan ya faru ne saboda gaskiyar cewa sake dubawa game da amfani da wannan magani yana da kyau sosai.
Analogs
Sauran nau'ikan insulin basal sune analogues na maganin Ryzodeg. Waɗannan sun haɗa da kwayoyi kamar insulin Glargin da Tujeo, waɗanda aka haɓaka a kan tushen insulin glargine da Levemir, wanda ya haɗa da insulin insulin.
Wadannan kwayoyi suna da kama sosai a cikin tasirin su, wanda suke da shi a jikin mai haƙuri. Saboda haka, lokacin sauya sheka daga Lantus, Tujeo ko Levemir zuwa Raizodeg, mara lafiya baya buƙatar sauya sashi, tunda an fassara shi a cikin 1: 1.
Bidiyo a cikin wannan labarin yana nuna yadda ake amfani da insulin yadda ya kamata.
