Ofloxin 400 magani ne a cikin rukunin fluoroquinolone. Yana da tasirin antimicrobial.
Sunan kasa da kasa mai zaman kansa
INN - Ofloxacin.
Ofloxin 400 magani ne a cikin rukunin fluoroquinolone.
Wasanni
J01MA01.
Saki siffofin da abun da ke ciki
Ana samar da magani a fannoni daban-daban: allunan, maganin shafawa, maganin kawa, saukad da mafita. Abubuwan da ke aiki a cikin kowane nau'i shine ofloxacin, quinolone na ƙarni na biyu.
Kwayoyi
Kwakwalwa tana kiyaye su kuma suna dauke da kayan aiki masu aiki a cikin sashi na 400 MG da 200 MG. Ingredientsarin sinadaran:
- sukari madara;
- sitaci masara;
- talc;
- hypromellose 2910/5.
Sanya cikin allunan 10 inji mai kwakwalwa. a cikin blisters.
Saukad da kai
Ceirƙira nau'ikan iri guda 2: ido da kunne. An gabatar da maganin a cikin hanyar bayyananne, a cikin 1 ml wanda ya ƙunshi:
- 3 MG naloxacin;
- bayani mai gishiri;
- benzalkonium chloride;
- hydrogen chloride;
- ruwa mai shirya.
Magunguna a cikin nau'i na ruwa an zuba shi a cikin kwalaben filastik. Tankuna suna da kayan sawa.
Ceirƙira nau'ikan iri guda 2: ido da kunne.
Foda
Wannan nau'in sakin ofloxacin ba ya nan.
Magani
Iya warware matsalar an yi nufin jiko. Tana da launi mai haske launin shuɗi. An zuba maganin a cikin vials a cikin adadin 100 ml. Baya ga abu mai aiki, akwai ƙarin abubuwan haɗi:
- bayani mai gishiri;
- Trilon B;
- hydrogen chloride;
- tsarkakakken ruwa.
Kafurai
An gabatar da wannan nau'in magungunan a cikin nau'i na kwalliyar gelatin rawaya. Abun ciki:
- ofloxacin - 200 MG;
- hypromellose;
- sodium lauryl sulfate;
- sukari madara;
- alli phosphate bisubstituted anhydrous;
- foda talcum.
Hakanan ana gabatar da maganin a cikin nau'i na kwalliyar gelatin rawaya.
Maganin shafawa
An samar da miyagun ƙwayoyi a cikin nau'i na maganin shafawa na nau'ikan 2: don magance raunuka da kuma magance cututtukan ido. Ofloxacin, wanda aka yi niyya don aikace-aikace ga fata, ana sayar da shi cikin shagunan 15 ko 30 g 1 g na miyagun ƙwayoyi ya ƙunshi abubuwa masu zuwa:
- 1 mg ofloxacin;
- 30 mg lidocaine hydrochloride;
- prolylene glycol;
- poloxamer;
- macrogol 400, 1500, 6000.
Ana samun maganin shafawa na ido a cikin shagunan 3 da 5 g.
- ofloxacin - 0.3 g;
- nipagin;
- nipazole;
- man fetur na jelly.
Kyandirori
A ƙarƙashin sunayen sunaye daban-daban, ana samarwa da sikarin ciki.
Aikin magunguna
Magungunan suna da kaddarorin kwayoyin cuta wanda ke haifar da hanawar kwayar halittar DNA (waɗannan enzymes waɗanda ke da alhakin haɗin kwayar halittar DNA a cikin ƙwayoyin microflora na pathogenic da haifuwarsu, har ila yau suna shiga cikin mahimman ayyukan: karkatar da karkace da tabbatar da kwanciyar hankali).
A miyagun ƙwayoyi yana da ƙwayoyin cuta na ƙwayoyin cuta waɗanda ke faruwa saboda hanawar DNA-gyrase.
Fluoroquinolone yana lalata harsashi na microflora na pathogenic, don haka yiwuwar haɓaka siffofin masu tsayayya kaɗan. Magungunan yana nuna matsakaicin aiki dangane da kwayoyin cuta na gram-korau. Ofloxacin, idan aka kwatanta shi da maganin Ciprofloxacin na kwayar cuta, zai ci gaba da aiki idan aka hada shi da amfani da inhibitors na RNA polymerase.
Abubuwan da ke aiki da miyagun ƙwayoyi suna lalata alaƙa tsakanin helices na DNA, sakamakon abin da ƙwayoyin ƙananan ƙwayoyin cuta suka mutu. Godiya ga wannan aikin maganin, ana amfani dashi don magance nau'ikan ƙwayoyin cuta waɗanda suke da tsayayya da sauran nau'ikan maganin rigakafi da sulfonamides.
Pharmacokinetics
Ana amfani da miyagun ƙwayoyi cikin sauri kuma gaba daya cikin hanji, ana lura da mafi girman yawan Ofloxacin a cikin jini jini bayan sa'o'i 1-3. Cire rabin rabin rayuwa shine 5-10 awanni, sakamakon wanda za'a iya shayar da maganin sau 1-2 a rana. Aƙalla 75-90% na miyagun ƙwayoyi suna barin jiki tare da fitsari.
Alamu don amfani
Ana amfani da Ofloxacin don bi da hanyoyin da za'a iya kamuwa da cuta
- tsarin urinary;
- gabobin mace da na namiji;
- STI
- hanjin ciki;
- ciki da jijiyoyin jini na biliary;
- tsarin biliary;
- nosocomial da postoperative;
- na numfashi;
- septicemia da bacteremia;
- Tsarin juyayi na tsakiya;
- tarin fuka, kuturta.
Maganin shafawa an nuna shi don magance fata, cututtukan hakori da raunuka masu kamuwa.
Contraindications
A miyagun ƙwayoyi yana da wadannan contraindications:
- rashin hankali ga abubuwan da aka gyara;
- ciki da hepatitis B;
- yara ‘yan kasa da shekara 18;
- amai da cututtukan hanji (bayan craniocerebral rauni da bugun jini);
- babban abun ciki na urea;
- lalacewar jijiyoyin da suka faru yayin ɗaukar fluoroquinolones;
- rashin sinadarin cytosolic (G6FD).
Tare da kulawa
Umarnin don amfani yana nuna cewa lokacin da ake rubuta magani, ya kamata a yi taka tsantsan a cikin marasa lafiya tare da waɗannan cututtukan masu zuwa:
- cerebral arteriosclerosis;
- rikicewar jijiyoyin kwakwalwa;
- aikin lalacewa mara kyau (tare da keɓantaccen izinin 50-20 ml / min);
- ƙarancin ci gaba da yanayin tsarin juyayi na tsakiya;
- rashin karfin zuciya tare da tsawan lokaci na QT.
Yadda ake ɗaukar Ofloxin 400
Ga mara lafiyar manya, yawan maganin yana maganin 200-600 MG. Yarda da kai a cikin kwanaki 7-10. Ana iya ɗaukar magani a cikin kashi na 400 MG sau ɗaya. Allunan ba za a iya ɗanɗana su ba, dole ne a haɗiye su gaba ɗaya, a wanke su da adadin ruwan da ake buƙata. Game da kamuwa da cuta mai tsanani da kiba, sashi zai iya zuwa 800 MG kowace rana.
A cikin lura da cututtukan kumburi na ƙananan sassa na urinary tsarin rashin daidaituwa, ana ɗaukar su 200 MG sau ɗaya a rana, hanya tana zuwa kwanaki 3-5. Don maganin cututtukan ƙwayar cuta, ƙwayoyi sun bugu sau ɗaya a kashi 400 MG.
Game da tsallakewar kashi
Idan saboda wasu dalilai haƙuri ba zai iya shan maganin ba, to za ku iya sha shi da zaran mutumin ya tuna wannan.
Tare da ciwon sukari
Marasa lafiya tare da cututtukan cututtukan masu ciwon sukari yayin jiyya tare da Ofloxin suna buƙatar saka idanu kan yawan haɗuwar glucose a cikin jini, saboda hadin gwiwar miyagun ƙwayoyi tare da magunguna masu rage sukari, insulin da fluoroquinolones na iya haifar da ci gaban hypo- ko hyperglycemia.
Marasa lafiya tare da cututtukan cututtukan masu ciwon sukari yayin jiyya tare da Ofloxin ya kamata su kula da yawan haɗuwar glucose a cikin jini.
Sakamakon sakamako na ofloxine 400
Kuma kodayake ana iya haifar da sakamako masu illa, idan an gano su, mai haƙuri ya kamata ya nemi likita.
Gastrointestinal fili
Wadannan alamun suna faruwa:
- zafi da rashin jin daɗi a cikin ciki;
- rikicewar dyspeptic;
- gastralgia;
- dysbiosis;
- rashin ci;
- hepatitis.
Hematopoietic gabobin
An lura:
- anemia
- leukopenia;
- pancytopenia;
- tabo na jini;
- thrombocytopenia.
Tsarin juyayi na tsakiya
Bayyanar cututtuka tare da lalacewar tsarin juyayi na tsakiya:
- Dizziness
- migraine
- Damuwa
- tashin hankali na bacci;
- psychosis da phobias;
- pressureara yawan matsa lamba na intracranial;
- hallucinations;
- jihar tawayar.
Daga tsarin musculoskeletal
An lura:
- tendonitis;
- rushewar tsoka;
- tsari mai kumburi a cikin kayan haɗin gwiwa-ligamentous;
- rauni na tsoka da jijiyoyin jiki.
Daga tsarin numfashi
Babu rashi.
A ɓangaren fata
Lura: petychia, kurji da dermatitis.
Daga tsarin kare jini
Irin wannan sakamako yana iya faruwa:
- hypercreatininemia;
- fitar;
- karuwa a cikin urea.
Daga tsarin zuciya
Marasa lafiya na iya haɓaka:
- zuciya tashin hankali;
- raguwa a cikin karfin jini;
- tachycardia;
- kumburi na jijiyoyin jiki;
- rushewar ci gaba.
Tsarin Endocrin
Babu rashi.
Cutar Al'aura
An bayyana rashin lafiyar rashin lafiyar ta hanyar bayyanar cututtuka masu zuwa:
- rashes;
- itching
- karancin numfashi
- rashin lafiyar nephritis;
- kumburi a fuska da wuya;
- rashin lafiyan ciwon huhu;
- Harshen Quincke na edema;
- amafflactic rawar jiki.
Tasiri kan ikon sarrafa abubuwan inji
Duk lokacin da ake yin jiyya tare da Ofloxin, haramun ne a tuka abin hawa da wasu injuna masu tsauri.
Umarni na musamman
Magungunan zai zama marasa amfani ga maganin cututtukan cututtukan cututtukan cututtukan, wanda ke da tasiri ga cututtukan cututtukan cututtukan cututtukan fata da cututtukan fata na huhu da cututtukan fata.
Game da samuwar alamomin rashin lafiyan, halayen da ba su dace ba game da tsarin juyayi na tsakiya, wajibi ne a soke maganin.
Yi amfani da lokacin daukar ciki da lactation
An haramta amfani da miyagun ƙwayoyi don amfani da mata yayin haihuwar yaro da lactation saboda ci gaban pathologies na gidajen abinci da jijiyoyin cikin yaron.
Magungunan ofloxine don yara 400
Marasa lafiya marasa lafiya 'yan shekaru 18 da haihuwa ba a sanya musu magani ba, saboda kuna buƙatar jira don kammala girma da samuwar ƙwayoyin tsoka. Amma idan ya cancanta, kuma a karkashin kulawa na likita, ana iya tsara Ofloxacin a sashi na 7.5 MG a 1 kg na nauyi. Matsakaicin wanda aka yarda da shi shine 15 MG / kg.
Marasa lafiya marasa lafiya 'yan shekaru 18 da haihuwa ba a sanya musu magani ba, saboda kuna buƙatar jira don kammala girma da samuwar ƙwayoyin tsoka.
Yi amfani da tsufa
Yi amfani da ƙwayar rigakafi tare da taka tsantsan saboda canje-canje da suka shafi shekaru da haɗarin mummunan halayen.
Aikace-aikacen aiki mara kyau
Ana buƙatar daidaita daidaitaccen sashi, kuma ana gudanar da magani a ƙarƙashin kulawar likita.
Amfani don aikin hanta mai rauni
Ana amfani da miyagun ƙwayoyi a ƙarƙashin yanayin da mai haƙuri zai sa ido a kai a kai game da maida hankali kan biliburin, kuma idan ƙwayar bile ta haɓaka, to an daidaita sashi ko kuma an soke maganin gaba daya.
Ofloxin 400 yawan abin sama da ya kamata
Waɗannan alamun alamun maye suna iya haɓaka:
- rikicewar dyspeptic;
- hauhawar jini
- rikicewa.
Idan an gano yawan abin sama da ya kamata, an dakatar da maganin, an wanke mara lafiyar a ciki a asibiti. Game da maye mai tsanani, ana iya wajabta maganin hemodialysis.
Yin hulɗa tare da wasu kwayoyi
Magungunan suna hulɗa daban da sauran kwayoyi.
Abubuwan haɗin gwiwa
An hana aiki tare da wakilin maganin rigakafi tare da kwayoyi masu zuwa:
- NSAIDs - resofar maɓallin Sebure na iya raguwa;
- quinolones da kwayoyi tare da na koda na koda - ofloxin matakin ya tashi kuma lokacin hutun nasa yana tsawaita;
- magungunan antihypertensive, barbiturates - hawan jini na iya ƙaruwa sosai;
- glucocorticoids - haɗarin haɗarin tendonitis;
- anthocyanins - ƙwaƙwalwar ƙwayar cuta ta rage.
Ba da shawarar haɗuwa ba
An haramta yarda da Ofloxacin tare da wadannan kwayoyi:
- antioxists na bitamin K - coagulation na jini na iya ƙaruwa;
- Glibenkamid - serum Glibenkamide matakin na iya ƙaruwa;
- yayin binciken, saboda kwayoyin, ana iya samun sakamako mara kyau na karya akan opiates da porphyrins a cikin fitsari.
Haɗuwa yana buƙatar taka tsantsan
Tare da yin amfani da Ofloxacin tare da maganin anticoagulants na baki, haɓaka ayyukan na ƙarshen mai yiwuwa ne.
Tare da haɗakar maganin rigakafi tare da kwayoyi waɗanda ke karya sinadarin sinus, ya zama dole don sarrafa ECG.
Amfani da barasa
Ba a amfani da miyagun ƙwayoyi tare da barasa.
Analogs
Ofloxacin yana da masu maye gurbin masu zuwa:
- Ofaxin;
- Oflo;
- Phloxane;
- Freagel;
- Ofor.
Magunguna kan bar sharuɗan
Da takardar sayan magani.
Zan iya siye ba tare da takardar sayan magani ba
A'a.
Farashin Ofloxin 400
Kuna iya siyan magani a Ukraine akan farashin 133.38-188 UAH., Kuma a Rasha - 160-180 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Adana ƙwayoyin rigakafi a cikin busassun wuri mai duhu ba tare da isa ga yara ba. Zazzabi kada ya wuce 25 ° C.
Ranar karewa
Bai wuce shekaru 3 ba.
Mai masana'anta
Jamhuriyar Czech.
Ofloxin Bincike 400
Likitoci
Maxim, Moscow: "A cikin aikina na likita, Ina amfani da fluoroquinolones don kula da marasa lafiya. Ofloxacin, Na yi la'akari da shi magani ne mai inganci. Yana ba da sakamako mai sauri kuma tabbatacce, ba tare da sakamako masu illa ba."
Galina, St. Petersburg: "Na kasance ina aiki a cikin ilimin mahaifa don shekaru 10. Saboda kumburi da gabobin urogenital, na sanya Ofloxacin ga mata. Daga cikin fa'ida, ingantacciyar hanyar sakin, ana iya lura da ikon sarrafawa da kula da sashi. Ya isa a sha maganin sau 1-2 a rana."
Lokacin shan magani, ƙwayar bugun jini na iya haɓaka.
Marasa lafiya
Anna, 38 shekara, Omsk: "Wannan magani ya taimaka wajen warkar da cutar cystitis mai zafi. Bayan kwanaki 2-3 na shan magani, yanayin ya inganta, saboda alamun cutar ya ɓace. Babu wasu sakamako masu illa, har ma da murkushewa bayan maganin rashin maganin rigakafi."
Yuri, dan shekara 29, Krasnodar: “Shekaru daya da suka gabata na kamu da mummunan sanyi a wurin aiki, wanda ya haifar da matsaloli game da yawan kumburi .. Likita ya ba da wannan magani, wanda na dauki tsawon mako guda. Kwayoyin suna aiki da sauri, saboda bayan kwana 3 alamomin sun fara bacewa. "
Tatyana, mai shekara 45, Voronezh: "Likita bayan gwaji ya bayyana ɓoyayyen kamuwa da cuta a cikina. An rubuto Ofloxacin, wanda na ɗauki kwanaki 10. Bayan gwajin na biyu, sakamakon ya kasance mara kyau."
