Don sanin wanda yafi kyau: Phasostabil ko Cardiomagnyl, ya kamata ku gwada waɗannan magungunan ta hanyar mahimman halaye. Don haka, da farko da yawa daga contraindication, alamomi, sakamako masu illa, da tsarin aiwatar da kwayoyi da kuma wani sa da kaddarorin da ake nazarin. Lokacin zabar, sashi na abubuwa masu aiki da nau'i na saki suna taka rawa.
Alamar halayyar Phasostabil
Abunda yake aiki shine acetylsalicylic acid (ASA) da magnesium hydroxide. Ana samun magungunan a cikin nau'ikan allunan. Ta kasance ta ƙungiyar antiplatelet jamiái. 1 kwamfutar hannu ya ƙunshi 75 MG na ASA da 15.2 MG na magnesium hydroxide. Abun da ya haɗa ya haɗa da wasu bangarorin waɗanda ba su nuna ayyukan antiplatelet ba:
- microcrystalline cellulose;
- croscarmellose sodium;
- povidone-K25;
- magnesium stearate.
Don sanin wanda yafi kyau: Phasostabil ko Cardiomagnyl, ya kamata ku gwada waɗannan magungunan ta hanyar mahimman halaye.
Allunan suna dauke da sinadarai, wanda ke taimakawa rage yawan sakin ASA da kare mucous membranes na ciki, da kuma duodenum daga mummunan tasirin maganin. Acetylsalicylic acid shine mai salicylic ester na acetic acid. Wannan abun yana cikin NSAIDs (magungunan anti-inflammatory marasa steroidal). Ana nuna shi ta hanyar haɗaka: ASA ta bayyana kanta azaman farfadiya, tana kawar da alamun kumburi, kuma tana daidaita yanayin zafin jiki.
Principleaƙƙarfan aikin wannan ɓangaren ya samo asali ne daga hanawar aikin COX isoenzymes da ke tattare da samar da prostaglandin daga arachidonic acid da thromboxane. Sakamakon haka, yawan tasirin tasirinsu ga jiki yana raguwa. Don haka, prostaglandins suna taka rawa sosai wajen haɓaka tsarin kumburi. Suna shafar hanyar inganta karuwar hankalin masu karba, ta haka ne suke bayar da tasu gudummawa ga karuwar zafin.
A ƙarƙashin rinjayar prostaglandins, juriya daga cibiyoyin hypothalamic da ke da alhakin thermoregulation zuwa mummunan tasiri na barbashi na pathogenic yana raguwa. ASA lokaci guda yana dakatar da duk hanyoyin da aka bayyana, saboda wanda aka rage yawan zafin kumburi, jin zafi da raguwar yawan zafin jiki nan da nan.
Abunda yake aiki shine acetylsalicylic acid (ASA) da magnesium hydroxide.
Kari akan wannan, wannan bangaren shima yana shafar tsarin tattarawar platelet. Wannan shi ne saboda gaskiyar cewa ASA yana hana ayyukan aikin endogenous thromboxane proaggregant. ASA shine mafi kyawun wakili na antiplatelet daga analogues da yawa, saboda yana tasiri aikin kai tsaye na thromboxane.
Koyaya, acetylsalicylic acid yana ba da sakamako mai laushi mai saurin illa. Wannan ya faru ne saboda gaskiyar cewa wannan abu yana hana COX-1 zuwa mafi girma. Isoenzymes na wannan rukunin suna cikin matakai daban-daban: shafar membrane na narkewa kamar jijiyoyin jini, na jini na jini.
Acetylsalicylic acid a ɗan lokaci yana rinjayar enzymes cyclooxygenase COX-2, wanda ke nufin yana ƙasa da adadin analogs a cikin tasiri na anti-mai kumburi, sakamako na analgesic. Bugu da ƙari, yayin yin jiyya tare da magani wanda ya ƙunshi wannan abun, an lura da yawan sakamako masu illa.
Phazostabil ya ƙunshi wani sashi mai aiki - magnesium hydroxide. Wannan abu yana daga rukuni na maganin antacids. An nuna shi ta hanyar tasiri mai kyau akan jikin mutum. Don haka, yayin ɗaukar acetylsalicylic acid da magnesium hydroxide, ana fitar da fili na magnesium chloride, saboda wanda mummunan tasirin hydrochloric acid wanda aka kirkira yayin metabolism na ASA shine keɓaɓɓe.
Lokacin da magnesium chloride ya shiga cikin hanji, yakan bayyana kansa a matsayin mai cin magani.
Bugu da kari, idan magnesium chloride ya shiga cikin hanji, to ya bayyana kansa a matsayin mai laxative. Wannan ya faru ne saboda gaskiyar cewa wannan abun ba ya shan komai. Bugu da ƙari, an lura da haɓakar matsin lamba na osmotic a cikin hanji. Hakanan, chloride an kirkiro yayin canzawar magnesium hydroxide magnesium chloride yana kunna peristalsis. Wannan ya faru ne saboda karuwar abubuwan da ke cikin hanji da kuma hauhawar matsin lamba a jikin bangon sa.
Godiya ga magnesium hydroxide, maganin ASA baya bayar da tasirin sakamako. A cikin matsanancin yanayi, yayin jiyya, halayen da ba a ambata ba su faɗi sosai fiye da yanayin da ake amfani da asfirin mai tsabta.
Pharmacokinetics na Phasostabil
Magunguna da ke cikin tambaya an canza su zuwa ga wani ɗan gajeren lokaci. Haka kuma, metabolization yana faruwa akan tsarin sha.
Acetylsalicylic acid an canza shi zuwa mafi girma a cikin hanta, inda ake fitar da metabolites, wanda aka rarraba cikin tsokoki da gabobin. Bayan minti 20, ana samun babban matakin maida hankali akan ASA. Ikon da za a ɗaura wa furotin plasma ya dogara da yawan ƙwayoyi.
A cikin aiwatar da cire acetylsalicylic acid, kodan sun shiga. Wannan yana nufin cewa yawancin abu ana cire shi ta hanyar urination. In babu raunin kuɗin yara, an cire maganin a bayan kwana 1-3. Idan cututtukan wannan kwayoyin sun haɓaka, sannu a hankali ASA yana tattarawa cikin kafofin watsa labarai na halitta (ruwa da kyallen takarda). Sakamakon ƙara ɗaukar wannan abu shine haɓakar rikice-rikice, tun da metabolites na acetylsalicylic acid suna da tasirin sakamako akan jiki.
A cikin aiwatar da cire acetylsalicylic acid, kodan sun shiga.
Manuniya da contraindications, sakamako masu illa
An tsara Phasostabil a cikin irin waɗannan halaye:
- rigakafin ci gaban cututtukan cututtukan cututtukan zuciya, musamman, gazawar zuciya, thrombosis a gaban abubuwan da ke haifar da haɗari, daga cikinsu akwai masu ciwon sukari, hauhawar jini, hauhawar jini;
- rigakafin alamun dawowar myocardial na maimaita cuta;
- matsanancin ciwon kirji;
- raguwa mai mahimmanci a cikin ƙwayar venous bayan tiyata tiyata.
Magunguna a cikin tambaya yana contraindicated da dama lokuta:
- rashin haƙuri ga abubuwa masu aiki na phasostabil ko wani maganin rashin kumburi steroidal;
- basur;
- Rashin bitamin K, wanda shine babban abin da ke bayar da gudummawa ga fitowar yanayin sha'awar zub da jini;
- rauni na zuciya;
- hare-haren fuka-fuka;
- hade da wani yawan pathological yanayi da kai ga keta numfashi aiki: Bronchial fuka, hanci polyposis, asfirin rashin ha} uri.
- m tsawon ci gaba na ciki;
- zub da jini na ciki;
- amfani da daidaitattun abubuwa na phasostabil da methotrexate;
- rashin glucose-6-phosphate dehydrogenase;
- mai rauni sosai na koda da aikin hepatic;
- lactation da ciki (I da III trimesters);
- yara ‘yan kasa da shekara 18.
Phasostabil yana da sakamako masu illa, waɗanda alamomi masu zuwa suka bayyana:
- yashwa na mucous membranes na ciki da ciki;
- jin zafi a ciki;
- tashin zuciya
- gagging;
- ƙwannafi;
- perforation na ganuwar da narkewa kamar fili;
- kumburi tare da sanyawa daga cikin rauni a cikin hanji.
- bronchospasm;
- raguwa a cikin matakan haemoglobin tare da anemia;
- canji a cikin abubuwan da ke tattare da jini da ke haɗuwa da yanayi kamar su thrombocytopenia, leukopenia, da sauransu;
- zub da jini
- tashin hankali na bacci;
- basur;
- karancin ji.
Cardiomagnyl Feature
Kuna iya siyan wannan kayan aiki a cikin nau'ikan allunan. Abun haɗin ya haɗa da kayan aikin guda ɗaya kamar yadda a cikin yanayin da aka yi la'akari da shi a baya: acetylsalicylic acid, magnesium hydroxide. Koyaya, ana gabatar da maganin a cikin nau'ikan daban-daban tare da matakai daban-daban na abubuwa masu aiki. Kwamfutar hannu 1 ta ƙunshi: 75 ko 150 MG na ASA; 15.2 ko 30.39 mg na magnesium hydroxide. Don haka, Cardiomagnyl yana haɓaka ta tsarin aiki kama da Phasostubil.
Za'a iya siyan Cardiomagnyl a cikin kwamfutar hannu. Haɗin ya haɗa da waɗannan abubuwa masu aiki kamar acetylsalicylic acid, magnesium hydroxide.
Kwatanta Miyagun Kwayoyi
Kama
Babban abin da ya hada hada kuɗin da aka tambaya shine asalin abubuwan iri ɗaya. Amfani da abubuwa masu aiki iri ɗaya a cikin samarwa yana ba ku damar samun kuɗin da suke aiki akan ƙa'ida ɗaya. A sakamakon wannan, Cardiomagnyl da Phasostabil suna tsokanar halayen da ba su dace ba. Iyakantacce a cikin wa’adin wa annan magungunan ma daidai suke. Yi amfani da magungunan da aka yi la'akari da su a cikin jiyya na cututtukan cututtukan cututtukan cututtukan nau'ikan.
Menene bambanci?
Cardiomagnyl yana wakilta da nau'ikan biyu waɗanda suka sha bamban akan sashi. Ofaya daga cikin zaɓuɓɓuka shine analog kai tsaye na Phazostabil (tare da ƙananan ƙwayar ASA da magnesium hydroxide). Don haka, lokacin da ake rubuta Cardiomagnyl wanda ya ƙunshi kayan aiki masu aiki a cikin adadin 150 da 30.39 mg (a cikin kwamfutar hannu 1), mutum zai iya dogara da haɓakar haɓaka. Ana samun sakamako mai kyau cikin sauri. Koyaya, sakamako masu illa na haɓaka sosai. Wannan yana nufin cewa haɗarin rikitarwa yana ƙaruwa, musamman daga narkewa.
Wanne ne mafi arha?
Phasostabil shine magani mafi araha. Ana iya siyan shi akan rubles 130. (fakitin dauke da allunan 100). Cardiomagnyl tare da sashi guda ɗaya (75 mg da 15.2 mg) yana biyan kuɗi 130 rubles, amma a wannan yanayin an nuna farashin kayan kunshin wanda ya ƙunshi Allunan 30
Cardiomagnyl yana wakilta da nau'ikan biyu waɗanda suka sha bamban akan sashi.
Wanne ya fi kyau: Phasostabil ko Cardiomagnyl?
Idan muka kwatanta shirye-shiryen tare da guda sikari na kayan aiki masu aiki, suna da tasiri iri guda. A lokaci guda, yawan sha abubuwa na ƙwayoyi yana canzawa, kamar yadda rabin rayuwar rayuwar abubuwa masu aiki. Dangane da karfin samun ingantaccen aiki, wadannan kwayoyi haka suke.
Shin ana iya maye gurbin Cardiomagnyl tare da Phasostabil?
Waɗannan kayan aikin musayar abubuwa ne. Koyaya, a cikin yanayin inda mai haƙuri ya ɓullo da mummunar amsa ga kowane ɗayan abubuwan da ke cikin Cardiomagnyl, ba za a iya amfani da Phazostabil ba, tunda magunguna biyu suna ɗauke da abubuwa guda.
Likitoci suna bita
Kartashova S.V., likitan zuciya, 37 years old, Tambov
Ana wajabta Cardiomagnyl sau da yawa ga marasa lafiya da suka girmi shekaru 40. Kayan aiki yana aiki da kyau: yana aiki kusan nan take, ƙari, sakamako masu illa da wahala ci gaba. Idan kun bi tsarin da aka tsara yayin maganin, to rikitarwa ba zai tashi ba.
Maryasov A.S., likitan tiyata, yana da shekara 38, Krasnodar
Phasostabil yana da rahusa fiye da Cardiomagnyl, amma ka'idodin aiki iri ɗaya ne. Duk magungunan biyu suna da tasiri. Koyaya, idan tsawan amfani da shi ya zama dole (alal misali, don rage haɗuwar platelet da hana haɗarin jini), Na fi son Phasostabil saboda ƙananan farashin.
Binciken haƙuri game da Phasostable da Cardiomagnyl
Galina, 46 years old, Saratov
Kudin Cardiomagnyl matsakaita ne, amma na cika da gamsuwa da wannan kayan aiki duka dangane da inganci da kuma matsayin tasirin tashin hankali a ciki. Na yi haƙuri da miyagun ƙwayoyi har sai an sami sakamako masu illa. Saboda wannan dalili, ban la'akari da wasu analogues, gami da kwayoyin, koda sun kasance mai rahusa.
Eugenia, mai shekara 38, St. Petersburg
A gare ni, Phasostabil shine mafi kyawun kayan aiki a cikin sashinsa, saboda yana da tasiri, yana taimakawa kawar da alamun alamun rashin ƙarfi na zuciya.
