Ciwon sukari mellitus tare da haɓaka wayewar ɗan adam yana zama abin da ya zama ruwan dare gama gari. A cewar kididdigar, 15% na yawan mutanen suna rashin lafiya tare da wannan rashin jin daɗi da iyakancewar rayuwa, kusan adadin su jahilai ne cewa suna da alamun farko na ciwon sukari ko kuma tuni sun kamu da cutar.
Dangane da wannan, ɗayan cikin uku na iya jin wannan cutar ta hanun su, don haka yana da mahimmanci don a riƙa yin bincike akai-akai don hana ko, a cikin mafi munin yanayi, bi daidai da cutar a duk rayuwa, yayin da kasancewa mutum cike da farin ciki.
Menene biguanides?
Biguanides sune magunguna na musamman waɗanda aka tsara don rage juriya na insulin jigilar ƙwayoyin jikin mutum ta hanyar rage yawan sukari da fats a cikin hanji. Suna ɗaya daga cikin hanyoyi masu yawa don magance ciwon sukari, wanda ke ɗauke da haɓaka matakin glucose na jini wanda ya sa ya zama sanadiyyar tsinkayar ƙwayar jini ko abinci mai ƙoshin lafiya.
Jerin abubuwan da ke cikin wannan rukunin sun hada da:
- Guanidine - Anyi amfani da shi sosai a cikin Turai ta tsakiya, amma a lokaci guda yana da guba ga hanta. Yanzu ba a amfani da shi;
- Sintalin - an yi niyya don magance wani nau'in cutar mai laushi, amma yawan guba da bayyanar insulin a cikin likitanci ya ba da gudummawar dakatar da karatun da ke da alaƙa, kodayake an yi amfani da miyagun ƙwayoyi har zuwa 40s na ƙarni na ƙarshe;
- Buformin da Fenformin - ya bayyana a cikin 50s na karni na 20, saboda buƙatar yin amfani da ingantattun magunguna don maganin cututtukan type 2, amma kuma ya bayyana matsaloli tare da ƙwayar gastrointestinal kamar yadda sakamako masu illa. Bugu da ƙari, an tabbatar da haɗarin su kuma an dakatar da tsauraran waɗannan kwayoyi. Yanzu zasu iya zama musanya ga Metformin ba bisa ƙa'ida ba saboda ƙarancin farashi, amma wannan haɗari ne mara tushe.
- Metformin (kadai aka ba da izini daga ƙungiyar da aka zaɓa, saboda ƙarancin haɗarin lactic acidosis). Hakanan, maganin ana kiranta Glucofage, Siofor. Akwai allunan da yawa a ciki wadanda aka hada su. Sakamakon bincike (har zuwa tsutsotsi kawai), an tabbatar da cewa a nan gaba, Metmorfin na iya zama "kwaya don tsufa" saboda abubuwan da ke kula da shi.
Hanyar aikin
Kamar yadda kuka sani, jikinmu zai iya samun sukari ta hanyoyi biyu:
- A waje da abinci.
- Ta hanyar gluconeogenesis a cikin hanta.
Don haka, akwai tsarin kula da matakan sukari a matakin ingantaccen yanayi. Da sanyin safiya, ana fitar da sukari a cikin jini kuma ya sadar da shi zuwa kwakwalwa, don haka ya samar da ingantaccen aiki. Amma idan ba mu ciyar da adadin daidai ba, to, za a adar da ragowar a jikin mutum a cikin kitse.
Zai fi kyau a ɗauki Metformin lokaci guda tare da abinci, ya fi dacewa a cikin jini yayin narkewar aiki fiye da kan komai a ciki. Abun yana aiki akan hepatocytes, yana kara yawan jijiyar kyallen takarda zuwa insulin kuma rage gudu guda sha a cikin hanji.
Tabbatacce sakamakon shan Metmorphine:
- tsayayyen raguwar shagunan mai;
- ci gaban ci;
- rage darajar sukari zuwa ƙa'idar aiki mai karɓa;
- raguwa a cikin glycated haemoglobin zuwa 1.5%;
- babu raguwa cikin glucose na jini bayan bacci da yunwar abinci a cikin marasa lafiya na rukuni na 2 da mutane masu lafiya;
- kunnawa lipolysis;
- hanawa na lipogenesis;
- ƙananan ƙwayoyin cuta;
- rage triglycerides;
- ƙananan matakan ƙananan lipoproteins mai yawa;
- rage yawan aikin platelet na hemostasis.
Side effects
Sakamakon sakamako wanda wannan ƙwayar cuta ke haifar da mafi yawan lokuta fiye da wasu, zasu iya yin aiki azaman:
- kumburi da na ciki ko kawai matsala;
- increasedara yawan taro na serotonin (hormone na farin ciki) a cikin hanji, wanda ke ƙarfafa aikinta kuma yana haifar da yawan zawo;
- bitamin B12 hypovitaminosis;
- fata fatar jiki;
- bayyanar lactic acidosis;
- rage testosterone a cikin maza;
- bayyanar cutar megaloblastic (da wuya).
Contraindications
An hana aikin Metformin cikin:
- shan giya, saboda gaskiyar cewa yana haifar da acidification na jini saboda raguwar sukari, kuma wannan yana da matukar haɗari;
- aiki mai ƙarfi na mutane ga mutane sama da 60;
- kasancewar mummunan yanayi tare da buƙatar ilimin insulin;
- ciki da lactation;
- gazawar koda ko wasu matsalolin koda;
- matsalolin hanta
- kasancewar lactic acidosis (lokacin da abun ciki na lactic acid a cikin jini ya wuce;
- kasancewar cututtukan cututtukan cututtukan zuciya (anemia, gazawar numfashi, gazawar zuciya);
- m urinary fili cututtuka;
- bronchopulmonary cututtuka;
- karancin abinci da rashin wadatar jiki.
Hulɗa da ƙwayoyi
An inganta aikin a hade tare da:
- Insulin
- Asiri;
- Acarbose;
- MAO masu hanawa;
- Cyclophosphamide;
- Clofibrate;
- Salicylates;
- ACE masu hanawa;
- Maganin Kawaus.
Wannan matakin ya raunana idan aka hada shi da:
- GCS;
- maganin hana haihuwa;
- kwayoyin hodar iblis;
- thiazide diuretics;
- abubuwan nicotinic a gare ku;
- Epinephrine;
- Glucagon
- Abubuwan Phenothiazine.
Tsakanin duka ƙungiyar Biguanides, Metformin mai araha ne, na duniya kuma mafi amfani wakili na warkewa. Idan aka gano alamun farko na rashin lafiya, ya kamata koyaushe ku nemi likita kuma kuyi gwajin jini. Tare da amfani da hankali na maganin a cikin allurai da aka tsara, zaku iya inganta lafiyar ku gaba ɗaya da kulawar marasa amfani, ba da sanin damuwar da ba dole ba.
Bidiyo daga Dr. Malysheva akan alamun farko na ciwon sukari:
Babban abin tunawa shine cewa ciwon sukari ba jumla bane, kuma cewa rashin jin daɗi daga farkon cutar za a iya rage ta ta bin abincin da umarnin likita.
