Contraindications, sakamako masu illa da kuma shawarwari masu mahimmanci don amfani da Fraxiparin

Matsaloli tare da coagulation na jini, rikitarwa na thromboembolic sune cututtukan da ke da matukar ƙarfi waɗanda ke buƙatar magani na gaggawa.

Sau da yawa a cikin irin waɗannan halayen, likitoci suna ba da magani ga Fraxiparin. Ana samun sakamako masu illa da contraindications don amfanin sa, kuma yana da mahimmanci a sani game da su.

Wadannan batutuwan, da kuma bayanai game da amfani da miyagun ƙwayoyi, tasirin sa da sake dubawa za a tattauna daga baya.

Aikin magunguna

Fraxiparin ya ƙunshi heparin nauyi mai ƙarancin ƙwaƙwalwa, abin da aka kirkira wanda aka aiwatar dashi don aiwatar da rashin ƙarfi. Siffar halayyar miyagun ƙwayoyi an ayyana ta aiki tare da daidaita coagulation factor Xa, kazalika da rauni na factor factor Pa.

Ayyukan Anti-Xa sun faɗi fiye da tasirin wakili akan lokacin aiki tare da farantin mara nauyi. Wannan yana nuna aikin antithrombotic.

Wannan magani yana da anti-mai kumburi da immunosuppressive sakamako. Haka kuma, aikin wakili ana iya lura dashi da sauri, kuma yana dadewa. A cikin sa'o'i 3-4, ana amfani da maganin gaba daya. An cire shi tare da fitsari a cikin kodan.

Alamu don amfani

Topical amfani da Fraxiparin a cikin wadannan yanayi:

• lura da infarction na zuciya na zuciya;
• hana rikicewar thromboembolic, alal misali, bayan tiyata, ko ba tare da tiyata ba;
• coagulation prophylaxis a lokacin hemodialysis;
• lura da rikitarwa na thromboembolic;
• lura da rashin lafiyar angina pectoris.

Nau'i na saki, abun da ke ciki

Sakin Fraxiparin yana cikin nau'i na mafita don allura, sanya shi cikin sirinji. Sirinjin kansa yana cikin fatar bakin ciki, wanda aka cakuda shi cikin guda 2 ko 10 a cikin kwali.

Abun ya haɗa da abu mai aiki wanda ake kira alli adroparin 5700-9500 IU. Abubuwan taimako a nan sune: alli hydroxide, ruwa mai tsafta, da chloric acid.

Side effects

Kamar yawancin magunguna, Fraxiparin wani lokaci yana haifar da sakamako masu illa:

• thrombocytopenia;
• halayen rashin lafiyan (yawanci daga Fraxiparin itchy ciki), gami da kumburin Quincke;
• zub da jini a wurare daban-daban;
• fata necrosis;
• hakikanin gaskiya;
• eosinophilia bayan cirewar magani;
• dawowar hyperkalemia;
• Samuwar ƙaramin hematoma a wurin allurar, wani lokacin manyan ɓarna daga Fraxiparin suma suna bayyana (hoto a ƙasa);
• haɓaka abubuwan da ke cikin enzymes na hepatic.

Wasu marasa lafiya da suka yi amfani da Fraxiparin sun lura da mummunan yanayin ƙonawa bayan allura.

Contraindications

Contraindications Fraxiparin yana da masu zuwa:

• thrombocytopenia;
• shekaru har zuwa shekaru 18;
• raunikan kwayoyin halitta na gabobin tare da dabi'ar zub da jini;
• toshewar jini na ciki;
• ji na ƙwarai zuwa abubuwan da aka wuce gona da iri;
• tiyata ko rauni ga idanu, kwakwalwa da kashin baya;
• zub da jini ko babban haɗarin abin da ya faru game da cutar hemostasis;
• mai tsanani gazawar sakamako wanda ya haifar da infarction na myocardial infarction, angina wanda ba zai iya tsayawa ba, magani na thromboembolism.

Tare da ƙara haɗarin zub da jini, ya kamata a ɗauka Fraxiparin tare da taka tsantsan. Yanayin sune kamar haka:

• gazawar hanta;
• raunin jijiyoyin jini a cikin retina da choroid;
• tsawanta magani fiye da shawarar;
• nauyin jiki har zuwa 40 kg;
• lokacin da ake gudanarwa a kan idanun, kashin baya, kwakwalwa;
• matsanancin hauhawar jini;
• rashin bin ka'idodin magani;
• cututtukan peptic;
• shan magunguna a lokaci guda wanda zai iya taimakawa zubar jini.

Umarnin don amfani

An shigar da Fraxiparin cikin ciki a cikin kasusuwa na kassar. Dole ne a kula da fatar fata a koyaushe yayin gudanar da maganin.

Ya kamata mai haƙuri ya kasance yana kwance. Yana da mahimmanci cewa allura ya zama tsayayye ne, kuma ba a kwana ba.

A cikin babban tiyata don rigakafin rikitarwa na thromboembolic, ana gudanar da maganin a cikin adadin 0.3 ml sau ɗaya a rana. Ana shan miyagun ƙwayoyi aƙalla mako guda har sai lokacin haɗarin ya wuce.

Ana amfani da kashi na farko kafin tiyata a cikin awa 2-4. Game da tiyata na orthopedic, ana bayar da maganin ne awanni 12 kafin aikin kuma sa'o'i 12 bayan kammala shi. Bugu da ƙari, ana shan miyagun ƙwayoyi na akalla kwanaki 10 har zuwa ƙarshen lokacin haɗarin.

An tsara sashi don yin rigakafi gwargwadon nauyin jikin mai haƙuri:

• 40-55 kg - sau ɗaya a rana don 0.5 ml;
• 60-70 kg - sau ɗaya a rana don 0.6 ml;
• 70-80 kg - sau biyu a rana, 0.7 ml kowace;
• 85-100 kg - sau biyu a rana don 0.8 ml.

Don lura da rikitarwa na thromboembolic, ana gudanar da maganin a cikin tsawan sa'o'i 12 sau biyu a rana don kwanaki 10.

A cikin lura da rikitarwa na thromboembolic, nauyin mutum yana taka rawa wajen tantance kashi:

• har zuwa kilogiram 50 - 0.4 mg;
• 50-59 kg - 0,5 mg;
• 60-69 kg - 0.6 mg;
• 70-79 kg - 0.7 MG;
• 80-89 kg - 0.8 MG;
• 90-99 kg - 0.9 mg.

A cikin rigakafin maganin coagulation na jini, yakamata a tsara adadin gwargwadon gwargwadon yanayin fasaha na dialysis. Yawanci, lokacin da aka hana coagulation, tsari shine farkon kashi na 0.3 MG don mutane har zuwa 50 kg, 0.4 mg zuwa 60 kg, 0.6 mg akan 70 kg.

Ana ba da shawarar jiyyar cutar ta myocardial infarction da angina mai tsayayye a hade tare da Asfirin na tsawon kwana 6. Da farko, an allurar da maganin a cikin babban catheter. Girman da aka yi amfani dashi shine 86 ME anti-Xa / kg. Abu na gaba, maganin yana gudana a ƙarƙashin ƙasa sau biyu a rana a cikin sashi ɗaya.

Yawan damuwa

Idan wani irin yawan ƙwayar yaɗuwa ya haifar da irin wannan ƙwayar, zub da jini mai yawa. Idan sun kasance marasa mahimmanci, to, kada ku damu. A cikin wannan halin, kuna buƙatar rage sashi, ko ƙara tazara tsakanin injections. Idan zub da jini na da mahimmanci, to, kuna buƙatar ɗaukar sulfate protamine, 0.6 MG wanda zai iya magance 0.1 MG na Fraxiparin.

Hulɗa da ƙwayoyi

Shan franksiparin lokaci guda tare da wasu magunguna na iya haifar da hyperkalemia.

Wadannan sun hada da: potassium salts, ACE inhibitors, heparins, NSAIDs, potassium-sparing diuretics, Trimethoprim, angiotensin II receptor blockers, Tacrolimus, Cyclosporin.

Magunguna waɗanda ke shafar hemostasis (kai tsaye anticoagulants, acetylsalicylic acid, NSAIDs, fibrinolytics, dextran), tare da yin amfani da wannan wakili, suna inganta tasirin juna.

Hadarin zubar jini yana ƙaruwa idan an kuma dauki Abciximab, Beraprost, Iloprost, Eptifibatide, Tirofiban, Ticlopedin. Acetylsalicylic acid kuma na iya ba da gudummawa ga wannan, amma a cikin allurai na antiplatelet, watau 50-300 mg.

Ya kamata a rubanya Fraxiparin sosai a hankali lokacin da marasa lafiya suka karɓi dextrans, anticoagulants kai tsaye, da corticosteroids na tsari. Game da ɗaukar anticoagulants kai tsaye tare da wannan magani, ana ci gaba da amfani dashi har sai alamar INR ta zama al'ada.

Nasiha

Kamar yadda yake da sauran magunguna masu yawa, akwai sake dubawa masu sabani game da Fraxiparin. Akwai waɗanda ya taimaka, kuma ana ɗaukarsa mai inganci, amma marasa lafiya waɗanda suke ɗaukar magani ba shi da wani amfani.

Nazarin ra'ayoyi mara kyau yana zuwa ne kan kasancewar yawan adadin sakamako masu illa, contraindications. A lokaci guda, duk da gargadin game da shan miyagun ƙwayoyi ga mata masu juna biyu, babu wani tasiri ga lafiya da haɓakar yarinyar da aka samu.

Bidiyo masu alaƙa

Yadda za a allurar Fraxiparin:

Saboda haka, Fraxiparin ne sau da yawa ana rubuta shi don matsalolin coagulation na jini, buƙatar magani ko hana rikicewar thromboembolic. Babban abu shine bin shawarwarin ƙwararrun masani waɗanda zasu iya ƙayyade dacewar yin amfani da shi da kuma gwargwadon da ake buƙata. In ba haka ba, ban da rashin tasiri, akasin haka, mummunan sakamako yana yiwuwa a hade da yawan abin sama da ya kamata, haɓakar zub da jini, da hauhawar jini.