Glidiab a cikin yaki da cutar sankarau

Glidiab magani ne na maganin cututtukan ƙwaƙwalwar ƙwaƙwalwa wanda ƙarfinsa yana nufin sarrafa nau'in ciwon sukari na 2: sake dawo da sarrafa glycemic, kawar da glucosuria (ƙara yawan haɗuwa da glucose a cikin gwajin fitsari).

Abun da magani

A cikin cibiyar sadarwar kantin magani Glidiab (a cikin tsarin kasa da kasa - Glidiab) za'a iya siyan ta a cikin nau'ikan allunan don amfani da baka. Abun da keɓaɓɓen abun da ke ciki da sababbin fasahohi suna ba da izini na ƙimar ingantaccen sakin kayan aiki. Launi mai rufi shine multivariate: fari, rawaya, cream.

A kan kwano a cikin sel mai keɓaɓɓu, allunan 10 masu nauyin 80 mg ana cakuda su tare da gliclazide mai aiki. An haɗu da shi tare da kayan karawa: sitaci, magnesium stearate, gestcolate sodium sitiri, sukari madara, hypromellose, MCC, talc.

1 kwamfutar hannu na miyagun ƙwayoyi Glidiab MV ya ƙunshi 30 MG na gliclazide. An inganta shi ta hanyar MCC, hypromellose, magnesium stearate, aerosil.

Hanyar magunguna

Ba kamar sabanin layin da ya gabata na magunguna ba, Glidiab ba shi da guba kuma ya fi tasiri, kuma halayenta na rashin lafiya sun ginu ne bisa hujjar cewa ƙarƙashin tasirin Glidiab:

• Ara yawan samarda insulin ta β-sel;
• An samar da glycogen samar da hepatic;
• Receptor sunadaran hana gluconeogenesis;
• Ingantaccen aikin insulin yana inganta;
• An toshe tsarin glucose daga sunadarai da mai a hanta;
• Kwayoyin hanta da kasusuwa suna dauke glucose da karfi sosai;
• Slows lipolysis a kyallen takarda.

Game da Glidiab, sake dubawar likitoci ya tabbatar mana cewa tare da yin amfani da maganin, jarin insulin na kyallen mahaifa yana raguwa, enzymes na wayar salula, musamman glycogen synthetase, ana kunna tazara, tazara tsakanin abinci da haɓakar insulin sosai.

Idan aka kwatanta da madadin magunguna na ƙungiyar sulfonylurea (glibenclamide, chlorpropamide), waɗanda ke aiki galibi a mataki na biyu na aikin hodar iblis, glycoslide yana taimakawa wajen dawo da farkon ƙarshen insulin da kuma rage mahimmancin glycemia. Bugu da ƙari ga ƙayyadaddun hanyoyin aikin metabolism, ƙwayar ta inganta haɓakar jini mai ƙarfi, rage ƙwayar platelet da haɗuwa, ta daina dakatar da ƙirƙirar filaye.

Dangane da umarnin, gliclazide:

• Yana inganta yanayin jijiyoyin jiki da kuma taƙasa;
• Amfani da shi don hana microthrombosis;
• Yana kwantar da hankalin jijiyoyin jijiyoyin bugun gini zuwa adrenaline;
• Dawo da zazzabin fibrinolysis (tsabtacewa daga hancin jini);
• Yana rage abun ciki na jimlar cholesterol, yana da tasirin anti-atherogenic (rigakafin cuta da tashin hankali na atherosclerosis);
• Yana dakatar da ayyukan ci-gaba na retinopathy a matakin da ba yaduwa ba.

Tsawaita yin amfani da Glidiab na yau da kullun ta masu ciwon sukari tare da cututtukan ƙwaƙwalwar ƙwayar cuta yana inganta haɗarin furotin a cikin fitsari. Magungunan ba ya bayar da gudummawa ga samun nauyi, tunda babban aikinsa yana farkon farkon samar da insulin, wanda baya tsokani cutar hyperinsulinemia. Magungunan yana ba da damar masu kiba masu cutar sukari har zuwa wani lokaci suna asara nauyi, sakamakon canjin rayuwa.

Pharmacokinetics na miyagun ƙwayoyi

Matsayin sha na gliclazide a cikin ƙwayar gastrointestinal bayan kula da maganin na miyagun ƙwayoyi yana da girma. Shan kashi ɗaya na maganin (80 MG) na samar da matsakaicin matakin mahimmin sashi a cikin jini bayan awa 4. Metabolites a cikin hanta suna biotransformed: hadawan abu da iskar shaka, ruwa da kuma glucuronidation suna haifar da samuwar metabolites 8 wanda yake tsaka tsaki dangane da glucose. Ofaya daga cikin metabolites yana da ikon shafar microcirculation. Kayan da ke lalata lalata sune kodan (70%) da hanjinsu (12%). A cikin ainihin sa, kawai 1% na Glidiab an cire. An cire ƙarshen rayuwar rabin a cikin kewayon 8-11.

Wanda aka wajabta wa Glidiab

Glidiab bisa ga umarnin hukuma don amfani ana bada shawarar ga masu ciwon sukari da ke fama da cutar ta 2 na matsanancin ƙarfi, lokacin da rikice-rikice kamar microangiopathy sun riga sun ci gaba. An ba shi damar amfani da miyagun ƙwayoyi don monotherapy ko a cikin hadaddun jiyya, tare da madadin magungunan hypoglycemic. An wajabta Glidiab tare da sauran magunguna masu rage sukari don hana rikicewar cututtukan cututtukan zuciya.

A kowane yanayi, an tsara maganin tare da isasshen tasiri na rashin magani ko kuma ƙari ga canjin rayuwa.

M cutar daga gliclazide

Magungunan glyclazide suna contraindicated:

• Masu fama da cutar siga da nau'in cuta ta 1;
• Tare da ci gaban labile na nau'in ciwon sukari na 2;
• Tare da ketoacidosis;
• Marasa lafiya tare da insuloma;
• A cikin yanayin da ke haifar da precocious da masu ciwon sukari;
• Mutane tare da na koda da hepatic kasawa;
• Tare da microangiopathy mai tsanani;
• Masu fama da cutar sankara a jiki tare da yawan kuzari zuwa ga sinadarin sulfonylureas;
• A lokacin cututtukan fata;
• A lokacin daukar ciki da lactation;
• A cikin ƙuruciya (babu wani bayani game da fa'ida da aminci);
• Awanni 48 kafin da bayan babban tiyata.

Yadda ake amfani da maganin

Kafin yin jigilar tsarin magani, likita ya kimanta yanayin yanayin mai haƙuri, shekaru, matakin cutar, da rikice-rikice masu alaƙa. Dangane da alamomin azumi da postprandial glycemia, da kuma kasancewar sauran magungunan maganin cututtukan da mai haƙuri ya ɗauka a layi ɗaya, ana lissafta adadin Glidiab na yau da kullun. Hakanan ana la'akari da haƙuri na mutum game da maganin kuma la'akari.

Don maganin gargajiya

Don sauƙi Glidiab, umarnin don amfani sun bada shawarar daidaitaccen ƙwayar magani - 80 MG / rana., Matsakaici - 160 MG, matsakaici - 320 MG. Amfani na biyu: da safe da maraice, kwamfutar hannu 1 kafin abinci. A cikin cututtukan koda, idan ƙirar creatinine ta kasa da raka'a 15, gyara kashi ba lallai ba ne.

Ga bambance-bambancen Glidiab MV

A cikin masu ciwon sukari (ciki har da nau'in gerontological), daidaitaccen kashi na miyagun ƙwayoyi tare da sakamako mai tsawo a farkon fara shine 30 MG. Gyara halin yana yiwuwa bayan kwanaki 14. Matsakaicin sashi na Glidiab MV, daidai da umarnin don amfani, shine 120 MG / day .. Wannan yayi daidai da guda 4. kwayoyin hana daukar ciki. Ana ɗaukar maganin ta baka da karin kumallo. An ba shi izinin ɗaukar wasu wakilai na hypoglycemic a layi daya: biguanides, hib-glucosidase enzyme inhibitors, insulin.

Sakamakon mara amfani

Game da sake duba Glidiab sun nuna cewa a wasu lokuta, magani yana haɗuwa da abubuwan da ba a tsammani ba.

Masu ciwon sukari suna koka game da gajiya, farin ciki, ciwon kai, pancytopenia, rashin lafiyan, pruritus, photoensitization, rashin lafiyar dyspeptic, asthenia, epigastric rashin jin daɗi, ƙarancin jijiya, zawo.

Diagnosedarancin da aka gano ana fama da su sune hypoglycemia, paresis, thrombocytopenia, leukopenia, agranclocytosis, anemia. A mafi yawancin halayen, ana iya jujjuya duk wasu cutarwa: bayan katse maganin, sun lalace da kansu.

Don guje wa hauhawar jini da sauran sakamakon da ba a so, yana da mahimmanci a sarari lokacin yin amfani da allunan don cin abinci, don guje wa yunwar abinci da kawar da giya gabaɗaya daga abincin.

Harkokin Magunguna da Glidiab

Yawan damuwa

Tare da karuwa a cikin ƙwayar da ya wuce warkewa, akwai yiwuwar raguwa mai mahimmanci a cikin alamun glycemic. Iousaukar cutar yawan zafin jiki na iya bayar da gudummawa ga ci gaban glycemic coma. Idan wanda aka azabtar yana sane kuma yana iya hadiye kwayar, ana ba shi sucrose, dextrose, glucose ko abinci mai daɗin ci (ba tare da kayan zaki ba).

A cikin mara lafiyar da bai san komai ba, ana gudanar da magunguna ta hanyar jijiya (40% dextrose) ko intramuscularly (1-2 g na glucagon). Bayan an dawo da hankali, dole ne a ba wa wanda ke cikin rauni carbohydrates a cikin sauri don hana sake komawa.

Form sashi

Za'a iya siyan magani na baki a sarkar kantin magani a cikin maganin kwaya. An samar da shi a cikin nau'ikan biyu: Glidiab talakawa (faranti guda 6 na guda 10. Kowace fakitin) da Glidiab MV, an canza shi ta hanyar sakin kayan mai aiki (faranti 3 ko 6 na kwatancen 10. A kowane akwati).

A kan farashin Glidiab mai sauƙin araha yana da araha sosai - 106-136 rubles. don allunan 60 na 80 MG. A kan Glidiab MV, farashin a cikin kantin magani na kan layi ya ɗan ɗanɗana: 160-166 rubles. don allunan 60 na 30 MG.

Dokokin ajiya

Glidiab baya buƙatar yanayi na musamman. Kayan aikin agaji na farko yakamata a aje shi daga tushen danshi, zafin zafin wuta da jan hankalin yara, dabbobi da kuma masu nakasa. Yanayin zafin jiki - har zuwa 25 ° С. Ana amfani da Allunan a cikin lokacin karewa: shekaru 4 don maganin Glidiab da shekara 1 don gyaran Glidiab MV ɗin sa. A ƙarshen lokacin ƙarewar da mai ƙira ya kafa, dole ne a zubar da maganin, tunda ana rage tasirinsa, kuma adadin illolin da ke haifar da haɓaka.

Daidaitawa da kwatancen Glidiab

Magungunan asali shine Gliclazide tare da abu guda mai aiki, duk sauran sune kwayoyin. Glidiab a cikin ranking an dauki mafi inganci. Dangane da bangaren aiki mai aiki (gliclazide) da rukunin (wakilan maganin antidiabetic), analogues tare da Glidiab iri daya ne: Gliclazide, Diagnizid, Diatika, Diabinax, Diabefarm, Diabresid, Diabetalong, Glioral, Predian, Gliclada, Dilo, Panmicron, Gluktam, Glisid, Medoklazid.

Daga cikin analogs din wanda wa’adinsu iri daya ne (nau'in ciwon sukari 2), wadanda suka fi fice sune: Lymphomyozot, Januvia, Multisorb, Bagomet, Glemaz, Metamin, Baeta, Apidra, Glyurenorm, Formmetin, Glyukobay, Novoformin, Levemir Flekspen, Formin, Levemir Penfill, Avandia, Pioglar.

Recommendationsarin shawarwari

Sakamakon magani tare da Glidiab zai yi raguwa sosai ba tare da gyara yanayin rayuwar masu ciwon sukari ba: karancin abinci mai narkewa a jiki, isasshen ƙwaƙwalwa ta jiki, sarrafa yanayin psychoemotional, mannewa ga bacci da hutawa.

Yana da mahimmanci a lura da bayanan glycemic ɗinka koyaushe ta hanyar bincika matakin sugars a gida da kuma cikin dakin gwaje-gwaje.

Tare da glucometer, ana kula da glycemia azumi akan komai a ciki da safe, sa'o'i 2 bayan cin abinci da kuma kafin lokacin bacci, da yamma.

Masu ciwon sukari da ke karɓar magani tare da shirye-shiryen insulin ya kamata su lura da abin da ke cikin jini kafin kowane allura na hormon. Yana da mahimmanci don waƙa da sauye-sauyen canje-canje a cikin masu nuna alama a cikin yini, kazalika da saka idanu matsakaicin karatun yayin watan - daga shawarwarin endocrinologist zuwa taro na gaba.

Magungunan zai iya yin tasiri a cikin halayen psychomotor. Wannan na iya haifarda matsaloli yayin tuki, tuki masu matattara, aiki a tsaunuka da sauran ayyukanda ke da haɗari waɗanda ke buƙatar taro.

Idan aka nuna Glidiab ga mahaifiyar masu shayarwa, ana iya amfani dashi kawai bayan canja wurin jaririn zuwa ciyarwar jabu.

Glidiab sake dubawa