Dokokin shan kwayoyi don matsa lamba Noliprel da sake dubawa na marasa lafiya

Noliprel magani ne na zamani wanda ke inganta alkawarin rage karfin jini. Abubuwa biyu masu aiki a cikin kwamfutar hannu guda ɗaya suna cika bukatun bukatun zamani don magance hauhawar jini. Irin waɗannan kwayoyi suna da tasiri sosai fiye da na yau da kullun, a ƙari, ba su da haɗarin haifar da sakamako masu illa. Don isa matakin matsin lamba (yawanci a ƙasa da 140/90), 50% na marasa lafiya masu hauhawar jini dole ne su ɗauki kwayoyi da yawa a lokuta daban-daban. Wannan tsarin magani ba shi da inganci, saboda yawancin marasa lafiya sun manta da shan kwaya akan lokaci. Haɗaɗɗen kan gado yana haɓaka haɗuwa da magani, tunda ana ɗauka sau ɗaya kawai a rana.

Wanene aka wajabta maganin?

Fiye da rabin mutane sama da 60 suna fama da hauhawar jini. Kowace shekara, wannan matsala ta zama mafi mahimmanci da gaggawa, kamar yadda a cikin rayuwar mutum ta zamani akwai ƙarin abubuwa masu haɗari don kara matsin lamba: damuwa, rashin motsi, nauyi mai nauyi, halaye marasa kyau, iska mai ƙazanta. Hawan jini shine ɗayan manyan abubuwanda ke haifar da bugun jini da cututtukan zuciya, don haka kuna buƙatar kulawa dashi nan da nan bayan ganowa.

Muhawara game da matsin lamba wacce za'a fara shan kwayoyin ta dade tana raguwa. Dangane da rarrabuwar da aka karɓa a duk faɗin duniya, matakin 120/80 ana ɗaukarsa al'ada ne, kuma ana ɗaukar matakin da ya dace da 139/89. Ana gano hauhawar jini ta Level 1 daga matakin 140/90. Tare da cututtukan sukari da cututtukan koda, ƙananan ƙarancin ba shi da ƙasa, an tsara allunan, farawa da lambobi 130/80. A farkon cutar, matsin lamba shine al'ada a mafi yawan lokuta, yana tashi ne lokaci-lokaci. Hanyoyin marasa magani suna da tasiri a wannan lokacin: rage cin abinci, daina nicotine da barasa, ayyukan yau da kullun, asarar nauyi. An haɗa magunguna idan ba zai yiwu a daidaita matsin lamba tare da waɗannan matakan ba.

A cewar likitoci, a karo na farko, yawancin marasa lafiya suna buƙatar magani ɗaya kawai tare da abu mai aiki. Idan irin wannan magani ba shi da amfani, yi amfani da magunguna da yawa na haɗari ko haɗuwa ɗaya. Noliprel ya ƙunshi ɗayan ingantattun haɗuwa da kayan aiki masu aiki, yana haɗar da inhibitor ACE da diuretic.

Fa'idodin magungunan haɗuwa:

1. Abubuwan da ke yin Noliprel suna shafar abubuwan da ke haifar da ci gaban hauhawar jini daga bangarori daban-daban, don haka haɗuwarsu tana da ƙarfi da kwanciyar hankali.
2. Ana samun raguwar matsi ta ƙananan allurai na abubuwa masu ƙarfi, don haka yawan tasirin da ba a ke so ya yi ƙasa.
3. Godiya ga haɗuwa da aka haɗa sosai, abu ɗaya yana rage tasirin sakamako na wani - diuretic yana hana hyperkalemia, wanda mai hana ACE zai iya tsokani.
4. Tasirin hada Noliprel yana haɓaka da sauri.
5. Mai haƙuri yana buƙatar shan kwamfutar hannu 1 kawai a rana, rashi ya faru sau da yawa fiye da lokacin shan 2-3 magunguna daban-daban, don haka tasiri na jiyya ya fi hakan yawa.

Iyakar abin da ke nuna amfanin Noliprel shine hauhawar jini. Wannan magani ne mai ƙarancin ƙananan magunguna wanda za'a iya tsara shi ga kowane mara lafiya wanda bashi da maganin cutar ciki. Zabi wasu kwayoyin hana daukar ciki don matsa lamba ya dogara ne da cututtukan hauhawar jini. Dangane da umarnin, Noliprel shine ɗayan magungunan da aka ba da shawarar don rage matsa lamba a cikin masu ciwon sukari, saboda ya ƙunshi ɗayan mafi aminci mafi dacewa ga masu ciwon sukari - indapamide. Hakanan an tsara shi sosai don ciwo na rayuwa, cututtukan zuciya na rashin ƙarfi, cututtukan zuciya, nephropathy, atherosclerosis.

Yaya maganin Noliprel

Haɗin abubuwa masu aiki a cikin allunan Noliprel ana daukar su ba ma kawai ba ne, har ma suna da tasiri sosai. Yana bayarda tasirin sakamako kai tsaye akan dalilai 2 na hauhawar jini:

1. Abubuwan da ke cikin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa sun kasance ga rukuni na magungunan hanawar ACE. Ya tsoma baki tare da aikin tsarin renin-angiotensin, saboda wanda aka daidaita matsa lamba a jikin mu. Perindopril yana hana haɓakar angiotensin na hormone, wanda ke da tasiri mai ƙarfi na vasoconstrictor. Hakanan yana tsawaita aikin bradykidin - peptide wanda ke yanke tasirin jini. Abinda ke taimaka wa perindopril: tare da tsawaita amfani, ba kawai yana rage matsin lamba ba, har ma yana rage kaya a kan jijiyoyin jini da zuciya, yana inganta yanayin ganuwar jijiyoyin jiki, dan kadan yana rage juriya insulin.
2. Na biyu abu a cikin abubuwan da ke tattare da Noliprel, indapamide, yana aiki daidai da turezide diuretics: yana haɓaka fitowar fitsari, yana haɓakar haɓakar sodium, chlorine, magnesium, potassium tare da fitsari. A lokaci guda, yawan ruwa a jiki yana raguwa, wanda ke haifar da raguwar matsin lamba a cikin tasoshin.

Ofaya daga cikin tasirin sakamako na masu hana ACE, da perindopril musamman, shine hyperkalemia, wanda zai iya tayar da tashin hankali na zuciya. Wannan halin yana tasowa ne sakamakon karancin sinadarin aldosterone, kwayar halittar wanda an tsara ta ta hanyar angiotensin II. Saboda kasancewar indapamide, wanda ke kawar da ƙwayar ƙwayar ƙwayar cuta mai yawa, lokacin ɗaukar Noliprel, yawan yawan hyperkalemia yana da ƙasa da ƙasa tare da kulawa tare da perindopril kadai.

Hawan jini da hauhawar jini za su kasance abubuwan da suka gabata - kyauta

Cutar zuciya da bugun jini sune sanadin kusan kashi 70% na duk mutuwar a duniya. Bakwai daga cikin mutane goma suna mutuwa saboda toshewar hanyoyin zuciya ko kwakwalwa. A kusan dukkanin lokuta, dalilin irin wannan mummunan ƙarshen shine guda ɗaya - matsin lamba akan hauhawar jini.

Yana yiwuwa kuma dole don sauƙaƙe matsi, in ba haka ba komai. Amma wannan ba ya warkar da cutar da kanta, amma kawai tana taimakawa wajen magance bincike, kuma ba dalilin cutar ba.

• Normalization na matsa lamba - 97%
• Cirewa kan jijiyoyin mara wuya - 80%
• Cire zuciyar mai karfin zuciya - 99%
• Cire ciwon kai - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare - 97%

Reviews daga likitocin zuciya game da Noliprel galibi tabbatacce ne. Kyakkyawan suna na miyagun ƙwayoyi yana da goyan bayan karatu da yawa.

Bayanai kan aikin Noliprel:

• a watan farko na jiyya, matakin matsin lamba yana raguwa a cikin kashi 74% na marasa lafiya, a watan uku - a cikin 87%;
• a cikin 90% na tsofaffi masu raunin haɓaka, bayan wata ɗaya na gudanarwa, ana iya rage ƙananan matsin lamba zuwa 90;
• bayan shekara guda na amfani, sakamako mai tasiri ya ci gaba cikin kashi 80% na marasa lafiya.
• miyagun ƙwayoyi suna aiki sosai a cikin marasa lafiya waɗanda ke buƙatar magani mai zafi: allurai masu yawa ko kwayoyi da yawa na antihypertensive. Yana nuna mafi kyawun sakamako tare da cututtukan ciwon sukari, da kuma hauhawar jini na ventricular hagu.
• Noliprel yana da babban aminci. Yawancin mummunan sakamako masu illa kusan babu bambanci da placebo.

A cikin lura da hauhawar jini, hukumar ta WHO ta ba da shawara maimakon a kara yawan magungunan da ke hade da juna don canzawa zuwa hada magunguna, kuma yana da kyau a fara shan magungunan marasa karfi. Allunan Noliprel sun cika duk waɗannan shawarwari.

Fitar saki da sashi

Wanda ya kirkiro Noliprel shine kamfanin samar da magunguna na Faransa Servier, wanda aka san shi da ci gaban da ya samu a fagen magance cututtukan zuciya da ciwon suga. A baya can, an samar da miyagun ƙwayoyi a cikin sigogi 2: Noliprel / Noliprel Forte. Tun daga 2006, abun da ke ciki ya canza, an fara amfani da wani gishirin perindopril. Saboda wannan, rayuwar shiryayye na Allunan ba tare da asarar inganci ya sami damar ƙaruwa da rabi. Sakamakon nauyin gishirin daban-daban na gishirin, dole a canza takaddun allunan dan kadan. Yanzu ana amfani da maganin a cikin sigogin 3:

Noliprel an samar da shi ta masana'antar Servier da ke Faransa da Rasha. Abubuwan da ke aiki don duk zaɓuɓɓukan sashi ana yin su ne kawai a Faransa.

Allunan Noliprel suna da sifar da ke da elongated, ana ba da kariya ta membrane fim, don dacewa an raba rabin kashi ana ba su da daraja. Marufi - kwalban filastik tare da allunan 30. Ba a samar da wani kamfanin shirya ba.

Yadda ake ɗauka

Tare da matakin matsin lamba na farko, ana iya tsara Noliprel nan da nan bayan gano cutar. Idan halin da ake ciki ba shi da mahimmanci (tare da hauhawar jini na 1), an fi son magunguna tare da kayan 1.

Dangane da umarnin, zaɓi na adadin Noliprel yana farawa da mafi ƙarancin matakai. Idan tare da taimakonsu ba zai yiwu a cimma matakin matsin lamba ba, ana ƙaruwa kashi. Magungunan ba ya kai ga iyakar ƙarfinsa kai tsaye, saboda haka yana da kyau a jira akalla wata 1 kafin a ƙara yawan sashi.

Tsofaffi masu raunin hawan jini kafin ɗaukar Noliprel, umarnin yin amfani da shi ya ba da shawarar cewa a ci gwaji don tantance lafiyar ƙodan.

M sakamako masu illa

Dukkanin hanawar ACE ana ɗaukar magunguna tare da babban lafiya. Ga Noliprel, bayanan haƙuri ba su da bambanci sosai da placebo.

Sakamakon sakamako na Noliprel sune:

• tashin hankali a farkon gudanarwa kuma tare da yawan zubar da jini (mita har zuwa 10%);
• tari, yana haɓaka ingancin rayuwa, amma ba haɗari ga huhun (kusan 10%);
• canji a cikin matakin potassium na jini (har zuwa 3%);
• m gazawar na koda a gaban pathology na kodan (har zuwa 0.01%);
• take hakki na samuwar ko haɓakar tayin (ba'a ƙaddara mita, tunda an haramta Noliprel yayin daukar ciki);
• rashin lafiyan abubuwa ga abubuwan Noliprel, Harshen Quincke (har zuwa 10%);
• rikicewar dandano (har zuwa 10%);
• raguwar haemoglobin (har zuwa 0.01%).

Dangane da umarnin, mafi yawan tasirin sakamako na Noliprel da analogues shine bushewa mai narkewa, mai kama da mai rashin lafiyar. Yana faruwa a farkon shekarar far. Mitar wannan sabon abu ba ya dogara da sunan miyagun ƙwayoyi da matsayin lafiyar mai haƙuri ba. Koyaya, tari shine 2 sau ƙasa da maza fiye da mata (a cikin duka ƙungiyar ACE inhibitors, 6% a gaban 14%), kuma a cikin Caucasians ƙasa da sau da yawa fiye da na Asians.

Dangane da sake duba marasa lafiya da ke shan miyagun ƙwayoyi, yawanci tari ne ke haifar da amai da amai, a cikin wani wuri kwance yana ƙaruwa. Lokacin ɗaukar Noliprel, yawan wannan sakamako na gefen shine, bisa ga ƙididdigar daban-daban, daga 5 zuwa 12%. Wasu lokuta ana iya magance matsalar tari tare da maganin cututtukan ƙwayoyi, amma har yanzu kusan kashi 3% na marasa lafiya ana tilasta su daina jiyya tare da Noliprel.

Na biyu mafi yawan gefen sakamako na miyagun ƙwayoyi shine hypotension a farkon kwanakin far. Umarni don amfani yana nuna cewa haɗarin ya fi girma a cikin tsofaffi masu raunin haɓaka, tare da bushewar ruwa (gami da amfani da maganin rashin daidaituwa), cututtukan ƙwayoyin da jijiyoyinsu. Marasa lafiya da ke da haɗarin hauhawar jini ya kamata su fara jiyya a ƙarƙashin kulawar likita, zai fi dacewa a asibiti. Ga sauran marasa lafiya masu kara kuzari, ya isa a bi ka'idodi masu sauki: fara farawa tare da karancin magani, cinye karin ruwa, rage gishiri a abinci, na wani lokaci a cikin kwanakin farko.

Allunan Noliprel na iya shafar potassium na jini. Rashin ƙwayar potassium, hypokalemia, ana lura dashi a kusan 2% na marasa lafiya, yawanci yakan bayyana kansa a matsayin karuwar gajiya, zafi ko cramps a cikin calves. Mitar yanayin jihar kishiyar, hyperkalemia, wanda aka nuna a cikin umarnin, ƙasa da 1%. Wannan yanayin yawanci yana faruwa a cikin cututtukan sukari da cututtukan koda.

Tasirin Noliprel akan haemoglobin ba shi da mahimmanci kuma baya haifar da haɗari na lafiya, yawanci ana iya gano shi ta hanyoyin dakin gwaje-gwaje.

Rashin iyawa na iya ɗanɗuwa. A cikin sake duba su, marasa lafiya masu kwantar da hankali suna kwatanta su a matsayin mai dandano mai ɗanɗano ko ƙarfe, raguwar ɗanɗano, kuma da wuya kamar saurin ƙonewa a bakin. A cikin manyan lokuta, waɗannan rikice-rikice suna haifar da asarar ci da ƙi shan Noliprel. Wannan sakamako na gefen yana dogara da yawan ƙwayoyi kuma yawanci yakan tafi da kanshi bayan watanni 3.

Contraindications

Magungunan da ke haɗuwa suna da abubuwa da yawa da yawa fiye da na al'ada, tunda masana'antun suna tantance haɗarin yin amfani da kowane abu mai aiki dabam.

Umarnin amfani da Noliprel ya haramta yin amfani da shi a lamurran da ke tafe:

1. Tare da hypersensitivity ga abubuwa masu aiki ko wasu abubuwan Noliprel, zuwa wasu magunguna na ƙungiyar inhibitor ACE, zuwa sulfonamides.
2. Idan a baya, lokacin ɗaukar masu hana ACE, mara lafiya yana da cutar Quincke.
3. Tare da hypolactasia: a cikin kwamfutar hannu Noliprel game da 74 mg na lactose.
4. A cikin ƙuruciya, tun da amincin babu ɗayan abubuwan da ke aiki na miyagun ƙwayoyi da aka bincika.
5. A cikin marasa lafiya da ke fama da cutar sankara ko kuma aikin nakasa mai rauni (GFR <60), bai kamata a ɗauki Noliprel lokaci guda tare da aliskiren ba saboda hulɗa da maganin.
6. A cikin cututtukan ciwon sukari, Noliprel an hana a wajabta shi tare da sartans (Losartan, Telmisartan da analogues), tunda wannan haɗin yana haɗarin haɗarin hyperkalemia da hypotension.
7. Sakamakon kasancewar a cikin abubuwan da ke tattare da diuretic, koda da gazawar hanta a cikin mawuyacin mataki su ne contraindications. A babban haɗarin lalacewa na koda, ƙarin saka idanu ya zama dole: gwaje-gwaje na yau da kullun (kowane watanni 2) don potassium da jini na creatinine.
8. A lokacin GW. Da miyagun ƙwayoyi yana hana lactation, na iya tsokani hypokalemia a cikin jariri, rashin lafiyar zuwa sulfonamides. Hadarin yana da girma musamman a farkon watanni na rayuwa. Umarnin don amfani yana bada shawarar maye gurbin Noliprel tare da wani, ƙarin binciken wakili na hypotensive na tsawon lokacin hepatitis B.
9. A lokacin daukar ciki, Noliprel na iya yin mummunan tasiri ga tayin. Perindopril ya ketare mahaifa cikin jinin jariri kuma yana iya haifar da hanyoyin haɓaka. A cikin makonni na farko, yayin da ake samar da gabobin, Noliprel ba shi da haɗari, don haka babu buƙatar katse ciki da ba a shirya ba. Matar ta kasance cikin gaggawa zuwa wata magungunan rigakafin ƙwayar cuta kuma ta sanya kulawa ta musamman don hanzarta gano cin zarafin da ta yiwu. Farawa daga watanni na biyu, Noliprel na iya haifar da hauhawar jini, gazawar koda a cikin tayin, matsalar rashin jini da kuma huhun ciwan huhu a cikin jariri, oligohydramnios, da kuma karancin isasshen jini.
10. Tare da haɗakar Noliprel tare da jami'ai don lura da arrhythmias, antipsychotics, antipsychotics, erythromycin, moxifloxacin, tachycardia na iya faruwa. An bayar da cikakken jigilar abubuwa masu haɗari a cikin umarnin.

Yarda da barasa tare da miyagun ƙwayoyi ba shi da kyau. Ethanol baya hulɗa tare da kayan aikin Noliprel, saboda haka, ba tsayayyen contraindication bane ga amfanin sa.Koyaya, tare da amfani na yau da kullun, barasa yana haifar da matsa lamba a koyaushe, watau, yana yin akasin Noliprel. Dangane da sake dubawa, har ma da shan giya guda ɗaya tare da wannan magani yana haifar da hawan jini mai haɗari da rashin lafiya ga kwanaki da yawa.

Analogs da wasu abubuwa

Cikakken analogs sune magunguna waɗanda ke ɗauke da abubuwa masu aiki iri ɗaya a sikari iri ɗaya kamar ainihin allunan. Ofarfin waɗannan magungunan daidai ne, saboda haka zasu iya maye gurbin Noliprel a kowane lokaci, lokacin shirye-shiryen da zaɓi na sabon kashi ba a buƙata.

Cikakkun analogues na Noliprel sune:

Sabbin shawarwarin don magance hauhawar jini yana nuna cewa canje-canje na magunguna akai-akai, canje-canje na magunguna ba a son su kuma yana iya haifar da ƙara matsa lamba. Shan magungunan haɗuwa ana ɗauka mafi inganci fiye da kulawa da magunguna guda biyu tare da abubuwa guda masu aiki. Idan ba zai yiwu a siyan Noliprel da aka tsara ba, zai fi kyau maye gurbin shi da cikakkun analogues. A wannan yanayin, yana da kyau a zabi magunguna daga sanannun Turai da manyan kamfanonin harhada magunguna na Rasha.

A cikin matsanancin yanayi, zaku iya maye gurbin Noliprel tare da allunan biyu. Babban abu shine a zabi madaidaicin sashi, dole ne yayi daidai da wanda likita ya umarta.

Zaɓuɓɓuka don irin waɗannan maye:

Kwatantawa da irin kwayoyi

Don daidaita matsin lamba, yawancin masu cutar hawan jini dole ne su ɗauki magunguna 2 zuwa 4. A farkon cutar, an wajabta maganin sartan ko ACE inhibitors (β-pril), tunda suna kiyaye kodan da zuciya fiye da sauran magunguna. Da zaran basu isa ba, ana wajabta diuretics a haƙuri ga mara haƙuri: ana ba da shawarar loopback diuretics koyaushe idan aka kasa cin nasara, ko kuma thiazide - in babu.

An haɗa matakan haɗuwa da zaɓi mafi kyawun zaɓi, shine, adadin abubuwan da ke aiki da yawa waɗanda aka ƙididdige su kuma aka tabbatar dasu a gwaje gwaje na asibiti tsakanin kwamfutar hannu ɗaya.

Haɗin thiazide diuretic da ta kwari shine mafi mashahuri kuma ɗayan mafi ƙarfi. Yana da tasiri a cikin tsofaffi masu fama da hauhawar jini tare da raunin zuciya. Mafi sau da yawa, hydrochlorothiazide yana haɗuwa tare da enalapril (Enap, Enafarm, Enam H), fosinopril (Fozid, Fozikard), lisinopril (Lisinoton, Lisinopril), captopril (Caposide). Babban fa'idar wannan haɗin shine rage yawan tasirin sakamako. Daga cikin waɗannan magungunan, ana daukar Noliprel ɗayan ɗayan aminci da aminci. Haka yake a cikin rukuni na rukunin magunguna na baya sune haɗarin diuretics tare da sartan - Lozartan N, Lozap Plus, Valsacor, Duopress da sauransu.

Ba shi yiwuwa a zaɓi mafi inganci daga haɗuwa na sama, tunda suna kusa da ƙarfin aiki. Babu wani bincike guda daya wanda zai tabbatar da ainihin fa'idodin magani ɗaya akan sauran.

Za a iya ɗaukar magungunan Noliprel tare da wasu abubuwa masu aiki (koda kuwa suna cikin rukuni ɗaya) za a iya ɗauka kawai bayan tuntuɓar likita. Lokacin canzawa zuwa wani magani, lallai ne ku sake zaɓar sashi kuma, sau da yawa fiye da yadda aka saba, sarrafa matsa lamba don hana yiwuwar tashin zuciya.

Neman Masu haƙuri