Amaryl ya ƙunshi glimepiride, wanda ke na sabon, na uku, ƙarni na abubuwan da suka samo asali na sulfonylurea (PSM). Wannan magani yana da tsada fiye da glibenclamide (Maninil) da glyclazide (Diabeton), amma bambancin farashin yana barata ta hanyar ingantaccen aiki, aiki mai sauri, sakamako mai sauƙi a cikin ƙwayar cuta, da ƙananan haɗarin hauhawar jini.
Tare da Amaril, sel beta suna sannu a hankali fiye da waɗanda suka gabata na sulfonylureas, don haka ci gaba da ciwon sukari yana raguwa kuma za a buƙaci maganin insulin daga baya.
Nazarin shan miyagun ƙwayoyi suna da kyakkyawan fata: yana rage sukari da kyau, ya dace don amfani, suna shan Allunan sau ɗaya a rana, ba tare da la'akari da kashi ba. Baya ga tsarkakakken glimepiride, an samar da haɗinsa tare da metformin - Amaril M.
Bruef umarnin
| Aiki | Yana rage sukarin jini, yana tasiri matakin sa a bangarorin biyu:
Bugu da ƙari, maganin yana rage haɗarin thrombosis, yana daidaita cholesterol, kuma yana rage damuwa. An cire Amaryl a cikin fitsari, wani bangare ta hanyar narkewa, saboda haka ana iya amfani dashi a cikin marasa lafiya da gazawar koda, idan an kiyaye ayyukan koda. |
| Alamu | Ciwon sukari iri iri ne kawai. Kayan aikin da ake buƙata don amfani da su an rage wasu ƙananan beta, ragowar ƙwayar insulin nasu. Idan maganin huhu ya daina fitar da ƙwayar jijiyoyin jiki, ba a sanya umarnin Amaril ba. Dangane da umarnin, ana iya ɗaukar maganin tare da metformin da insulin far. |
| Sashi | Ana samar da Amaryl a cikin nau'ikan allunan da ke dauke da nauyin 4 har zuwa glimepiride. Don sauƙi na amfani, kowane sashi yana da launi. Maganin farawa shine 1 MG. Ana ɗaukar shi na kwanaki 10, bayan haka sun fara hankali har sai sukari ya saba. Matsakaicin adadin izini shine 6 MG. Idan ba ta ba da diyya ga ciwon sukari ba, kwayoyi daga wasu ƙungiyoyi ko insulin suna ƙara cikin tsarin kulawa. |
| Yawan damuwa | Wucewa matsakaicin matsakaicin yana haifar da tsawan hypoglycemia. Bayan al'ada na sukari, zai iya fadi akai-akai don wani kwanaki 3. Duk wannan lokacin, mai haƙuri ya kamata ya kasance a ƙarƙashin kulawa da dangi, tare da ƙarfin zubar da jini - a asibiti. |
| Contraindications |
Amaryl an dakatar da shi na ɗan lokaci kuma an maye gurbin shi da injections na insulin a lokacin daukar ciki da lactation, matsanancin rikice-rikice na ciwon sukari, daga ketoacidosis zuwa cutar hyperglycemic. Tare da cututtuka masu kamuwa da cuta, raunin da ya faru, yawan motsin rai, Amaril bazai isa ya daidaita sukari ba, don haka ana inganta magani tare da insulin, yawanci mai tsawo. |
| Hadarin cututtukan jini | Ciwon sukari na jini ya fadi idan mai ciwon sukari ya manta cin abinci ko bai cika glucose da aka kashe yayin motsa jiki ba. Don daidaita yanayin glycemia, kuna buƙatar ɗaukar carbohydrates mai sauri, yawanci yanki na sukari, gilashin ruwan 'ya'yan itace ko shayi mai zaki. Idan kashi na Amaril ya wuce, hypoglycemia na iya dawowa sau da yawa a lokacin maganin. A wannan yanayin, bayan na farko da sukari na sukari, suna ƙoƙarin cire glimepiride daga narkewa: suna tsokanar matsananciyar ruwa, sha masu adsorbents ko maganin laxative. Iousaukar cutar yawan ƙwayar cuta yana da mutuƙar mutu'a; magani ga mummunan jini ya haɗa da glucose na cikin jiki. |
| Side effects | Baya ga hypoglycemia, lokacin ɗaukar Amaril, ana iya lura da narkewar matsala (a cikin ƙasa da 1% na marasa lafiya), rashin lafiyan jiki, daga fyaɗe da itching zuwa girgiza anaphylactic (<1%), halayen daga hanta, canje-canje a cikin tsarin jini (<0.1%) . |
| Ciki da GV | Umarni a takaice ta hana yin magani tare da Amaril yayin daukar ciki da HBV. Magungunan yana ratsa shingen cikin mahaifa ya shiga jini tayi, ya shiga cikin nono. Idan mai ciki ko mai lasawa mai ciwon sukari bai daina shan maganin ba, to yarinyar tana cikin haɗarin hypoglycemia. |
| Hulɗa da ƙwayoyi | Sakamakon Amaril na iya canzawa tare da amfani da wasu kwayoyi na lokaci guda: hormonal, antihypertensive, wasu ƙwayoyin rigakafi da wakilai na antifungal. Cikakken jerin yana ƙunshe cikin umarnin don amfani. |
| Abun ciki | Abubuwan da ke aiki shine glimepiride (Amaril M yana da glimepiride da metformin), kayan abinci masu taimakawa don samar da kwamfutar hannu da kuma ƙara rayuwa mai tsari: sodium glycolate, lactose, cellulose, polyvidone, magnesium stearate, fenti. |
| Mai masana'anta | Kamfanin Sanofi, Glimepiride an sanya shi a cikin Jamus, allunan da kuma shirya a Italiya. |
| Farashi | Amaryl: 335-1220 rub. don allunan 30, farashin ya dogara da sashi. Kunshin mafi girma - Allunan 90 na 4 MG kowane farashin kusan 2700 rubles. Amaril M: 750 rub. na allunan 30. |
| Adanawa | Shekaru 3 Ya kamata a adana magungunan ta hanyar isa ga yara, kamar yadda amfani da Amaril mara amfani da shi zai iya zama cutarwa ga lafiyar. |
Dokokin shigar da kara
An tsara allunan Amaryl a lokuta biyu:
- Idan ciwon sukari bai wuce shekara ta farko ba, kuma metformin bai isa ya rama ba.
- A farkon jiyya, tare da metformin da abinci, idan an gano babban haemoglobin mai narkewa (> 8%). Bayan da aka rama cutar, buƙatar rage ƙwayoyin maganin ƙwaƙwalwa ta ragu, kuma an soke Amaryl.
Ana ɗaukar miyagun ƙwayoyi tare da abinci.. Ba za a iya murƙushe kwamfutar hannu ba, amma za'a iya raba shi cikin rabi da haɗari. Kulawar Amaril yana buƙatar gyara abinci mai gina jiki:
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
- Abincin da suke shan kwayoyin zai kasance mai yawa;
- A kowane hali ya kamata ku tsallake abinci. Idan ba zai yiwu a sami karin kumallo ba, ana maraba da liyar da Amaril zuwa abincin dare;
- Ya zama dole don tsara wadataccen abinci na carbohydrates a cikin jini. Ana cimma wannan burin ta hanyar abinci akai-akai (bayan sa'o'i 4), rarrabuwar carbohydrates a cikin dukkan jita-jita. Lowerarin ƙananan ƙididdigar glycemic na abinci, mafi sauƙi shine cimma biyan diyya.
Amaril ya bugu tsawon shekaru ba tare da shan hutu ba. Idan matsakaicin kashi ya daina rage sukari, a hanzarta buƙatar canzawa zuwa ilimin insulin.
Lokacin aiki
Amaryl yana da cikakken bioavailability, 100% na miyagun ƙwayoyi sun isa wurin aikin. Dangane da umarnin, an samar da mafi girman taro na glimepiride a cikin jini bayan awa 2.5. Jimlar aikin ta wuce sa'o'i 24, mafi girman sashi, mafi tsawan matakan Amaril za su yi aiki.
Saboda tsawon lokacinta, an yarda da shan maganin sau daya a rana. La'akari da cewa kashi 60 cikin dari na masu ciwon sukari basa son bin umarnin likita, kashi daya na iya rage tsadar kwayoyi daga kashi 30%, sabili da haka inganta yanayin ciwon sukari.
Amfani da barasa
Giya na shafar Amaryl ba tare da tsammani ba, za su iya haɓakawa da raunana tasirinsa. Rashin haɗarin haɗarin haɗari na rayuwa yana ƙaruwa, farawa da matsakaicin matakin maye. A cewar masu ciwon sukari, wani hadari na barasa shine bai wuce gilashin vodka ko gilashin giya ba.
Anail na Ammaril
Magungunan suna da analogues masu yawa masu rahusa tare da abu guda mai aiki da sashi, abin da ake kira ƙwaƙwalwa. Ainihin, waɗannan sune allunan samarwa na gida, daga samfuran shigo da zaka iya sayan kawai Croatian Glimepirid-Teva. Dangane da sake dubawa, analog ɗin Rashanci bai zama mafi muni ba daga shigo da Amaril.
| Anail na Ammaril | Kasar samarwa | Mai masana'anta | Farashi don ƙaramin matakin, rub. |
| Glimepiride | Rasha | Atoll Vertex Magunguna Pharmstandard-Leksredstva, | 110 |
| Canyon Glimepiride | Canonfarm Production. | 155 | |
| Diamerid | Akrikhin | 180 | |
| Glimepiride-teva | Kuroshiya | Pliva na Khrvatsk | 135 |
| Glemaz | Kasar Argentina | Kimika Montpellier | babu a cikin magunguna |
Amaryl ko masu ciwon sukari
A halin yanzu, glimepiride da tsawan tsari na glyclazide (Diabeton MV da analogues) ana ɗaukarsu PSM ta zamani kuma mai aminci. Duk magungunan biyu suna da ƙarancin magabata fiye da waɗanda suke haifar da su don haifar da mummunan hypoglycemia.
Duk da haka, Amaryl Allunan don ciwon sukari sun fi dacewa:
- suna shafar nauyin marasa lafiya ƙasa da;
- ba haka bane mummunan sakamako akan tsarin zuciya;
- masu ciwon sukari suna buƙatar ƙananan kashin na miyagun ƙwayoyi (matsakaicin yawan masu ciwon sukari shine kusan milimita 3 na Amaril);
- raguwar sukari yayin shan Amaril yana haɗuwa da ƙananan karuwa a cikin matakan insulin. Ga masu ciwon sukari, wannan rabo 0.07, don Amaril - 0.03. A cikin ragowar PSM, rabo ya zama mafi muni: 0.11 don glipizide, 0.16 don glibenclamide.
Amaryl ko Glucophage
Daidaitaccen magana, tambayar da ko Amiil ko Glucophage (metformin) bai kamata ya kasance a sanya su ba. Glucophage da analogues na nau'in ciwon sukari na 2 ana wajabta su koyaushe a farkon wuri, tunda sun fi dacewa fiye da sauran kwayoyi suna aiki akan babban dalilin cutar - juriya insulin. Idan likita ya rubuta allunan Amaryl kawai, cancanta ya cancanci yin shakka.
Duk da aminci na kamfani, wannan magani kai tsaye yana maganin cututtukan fitsari, wanda ke nufin hakan yana rage girman aikin insulin. Anyi maganin PSM ne kawai idan ba'a yarda da metformin ko kuma gwargwadon ƙarfinsa bai isa ba don maganin al'ada. A matsayinka na mai mulki, wannan ko dai mummunar ɓarna ce ta cutar sankara, ko kuma rashin lafiya na dogon lokaci.
Amaril da Yanumet
Yanumet, kamar Amaryl, yana shafar duka matakan insulin da juriya insulin. Kwayoyi sun bambanta a cikin tsarin aiwatarwa da tsarin sinadarai, don haka za'a iya haɗasu tare. Yanumet wani sabon magani ne mai mahimmanci, saboda haka yana farashi daga 1800 rubles. ga mafi ƙaramin fakiti. A cikin Rasha, ana yin rajista ta analogues: Combogliz da Velmetia, waɗanda ba su da arha fiye da na asali.
A mafi yawan lokuta, ana iya biyan diyya ta hanyar haɗuwa da ƙananan metformin, abinci, motsa jiki, wani lokacin marasa lafiya suna buƙatar PSM. Yanumet ya cancanci siyan kawai idan farashin sa bai da mahimmanci ga kasafin.
Amaril M
Rashin yarda da masu ciwon sukari tare da warkewar magani shine babban dalilin rage cutar sukari. Sauƙaƙe tsarin kulawa don kowane cuta na yau da kullun yana inganta sakamakonta, saboda haka, ga marasa lafiya zaɓin zaɓi, an fi son magungunan haɗuwa. Amaryl M ya ƙunshi mafi yawan haɗuwa da kwayoyi masu rage sukari: metformin da PSM. Kowace kwamfutar hannu ta ƙunshi 500 MG na metformin da 2 MG na glimepiride.
Ba shi yiwuwa a daidaita daidaitattun abubuwa guda biyu a cikin kwamfutar hannu ɗaya don marasa lafiya daban-daban. A tsakiyar mataki na ciwon sukari, ƙarin metformin, ana buƙatar glimepiride ƙasa. Ba a yarda da 1000 mg na metformin ba a lokaci guda, marasa lafiya da ke da mummunar cuta dole ne su sha Amaril M sau uku a rana. Don zaɓar ainihin sashi, yana da kyau ga marassa lafiyar su ɗauki Amaril daban da karin kumallo da Glucofage sau uku a rana.
