Galvus magani ne na likitanci wanda aikinsa yayi niyya don magance cututtukan type 2. Babban sashi mai amfani da maganin shine Vildagliptin. Ana samun wannan maganin ta hanyar Allunan. Wannan magani yana da kyakkyawan bita daga likitoci da masu haƙuri.
Ayyukan vildagliptin yana dogara ne akan kumburin farji, shine aikin islet ɗin sa. Wannan yana haifar da raguwa mai zaɓi a cikin samar da enzyme dipeptidyl peptidase-4.
Rage hanzari a cikin wannan enzyme yana haɓaka haɓakar ƙwayar glucagon-type 1 peptide da polypeptide na glucose-glucose.
Alamu don amfani
Ana amfani da maganin a cikin maganin cututtukan type 2:
- kamar yadda kawai magani a hade tare da abinci da aikin jiki Reviews sun nuna cewa irin wannan magani yana ba da sakamako mai ɗorewa;
- a haɗe tare da metformin a farkon farawar magani, tare da ƙarancin sakamako na abinci da ƙara yawan motsa jiki;
- ga mutanen da suke amfani da analogues dauke da vildagliptin da metformin, misali Galvus Met.
- don hadaddun amfani da kwayoyi dauke da vildagliptin da metformin, kazalika da ƙari da kwayoyi tare da sulfonylureas, thiazolidinedione, ko tare da insulin. Ana amfani dashi a cikin lokuta na rashin kulawa tare da monotherapy, kazalika da abinci da aikin jiki;
- a matsayin magani na sau uku a cikin rashin sakamakon amfani da magunguna wanda ke dauke da abubuwan da suka samo asali na sulfonylurea da metformin, wanda aka yi amfani da shi a kan yanayin cewa abincin da haɓaka aikin jiki;
- azaman maganin sau uku a cikin rashin sakamako na amfani da kwayoyi dauke da insulin da metformin, wanda aka yi amfani da shi a baya, wanda ya shafi abinci da ƙara yawan motsa jiki.
Allurai da hanyoyin amfani da maganin
An zaɓi adadin wannan magani daban-daban ga kowane mara lafiya dangane da tsananin cutar da haƙurin mutum na maganin. Amincewa da Galvus yayin rana bai dogara da abincin abinci ba. Dangane da sake dubawa, lokacin yin bincike, an tsara wannan magani nan da nan.
Wannan magani tare da monotherapy ko a hade tare da metformin, thiazolidinedione ko insulin ana ɗauka daga 50 zuwa 100 MG kowace rana. Idan yanayin halin mai haƙuri ya kasance mai tsanani kuma ana amfani da insulin don daidaita matakin sukari a cikin jiki, to, maganin yau da kullun shine 100 MG.
Lokacin amfani da kwayoyi uku, alal misali, vildagliptin, abubuwan tushe na sulfonylurea da metformin, tsarin yau da kullun shine 100 MG.
Ana ba da shawarar kashi 50 na MG a sha ɗaya da safe, za a raba kashi 100 na MG zuwa kashi biyu: 50m da safe da iri ɗaya da yamma. Idan saboda wasu dalilai an rasa magani, dole ne a ɗauka da wuri-wuri, alhali ba a wuce magunguna na yau da kullun ba.
Adadin yau da kullun na Galvus a cikin lura da magunguna biyu ko fiye shine 50 MG kowace rana. Tun da magungunan da ake amfani da su a cikin hadaddun farji tare da Galvus suna inganta tasirin sa, kashi na yau da kullum na 50 MG ya dace da 100 MG kowace rana tare da monotherapy tare da wannan magani.
Idan har ba a cimma tasirin maganin ba, ana bada shawarar ƙara yawan ƙwayar magunguna zuwa 100 MG kowace rana, sannan kuma a rubuto metformin, sulfonylureas, thiazolidinedione, ko insulin.
A cikin marasa lafiya tare da rikice-rikice a cikin aiki na gabobin ciki, irin su kodan da hanta, matsakaicin adadin Galvus bai wuce 100 MG kowace rana ba. Game da ƙarancin raunin aiki a cikin aikin ƙodan, kashi na yau da kullun na miyagun ƙwayoyi ya zama bai wuce 50 MG ba.
Analogs na wannan magani, tare da wasa don matakin lambar ATX-4: Onglisa, Januvia. Babban analogues tare da abu mai aiki shine Galvus Met da Vildaglipmin.
Nazarin haƙuri game da waɗannan kwayoyi, kazalika da bincike suna ba da shawarar musayar su a cikin maganin cututtukan ƙwayar cuta.
Bayanin magani na Galvus Met
Ana ɗaukar Galvus Met a baki, an wanke shi da ruwa mai yawa. An zaɓi kashi na yau da kullun na miyagun ƙwayoyi daban-daban ga kowane, duk da haka, an ba da cewa iyakar ƙwayar miyagun ƙwayoyi bai wuce 100 MG ba.
A matakin farko, an tsara adadin maganin da aka ƙera yana yin la'akari da allurai na baya da aka ɗauka na vildagliptin da / ko metformin. Don kawar da sakamako masu illa daga tsarin narkewa, ana shan miyagun ƙwayoyi tare da abinci.
Idan jiyya tare da vildagliptin bai ba da tasirin da ake so ba, to ana iya yin maganin Galvus Metom. Ga masu farawa, ana bada shawarar kwayar 50 a cikin sau biyu a rana, bayan haka zaku iya ƙara yawan har sai an sami sakamako.
Idan magani tare da metformin ba shi da tasiri, gwargwadon adadin da aka riga aka tsara, Galvus Met an ba da shawarar a dauki shi gwargwadon metformin a cikin adadin 50 mg / 500 mg, 50 mg / 850 mg, 50 mg / 1000 mg. Ya kamata a raba kashi na maganin a kashi biyu.
Idan an tsara vildagliptin da metformin, kowane a cikin nau'i na allunan daban, to ana iya tsara Galvus Met ban da su, azaman ƙarin jiyya a cikin adadin 50 MG kowace rana.
A haɗuwa da magani tare da kwayoyi waɗanda ke ƙunshe da abubuwan samo asali ko insulin, ana lissafta adadin maganin a cikin tsari mai zuwa: 50 mg 2 sau a rana azaman analog na vildagliptin ko metformin, a cikin adadin da aka ɗauki wannan magani.
Galvus Met yana cikin contraindicated a cikin marasa lafiya waɗanda ke da nakasa aiki na koda ko kuma gazawar koda. Wannan ya faru ne saboda gaskiyar cewa Galvus Met da abubuwa masu aiki sun keɓe daga jiki ta amfani da kodan. A cikin mutane masu shekaru, aikin waɗannan gabobin suna raguwa a hankali.
Wannan halayyar halin mutum ne wanda ya girmi shekaru 65. An tsara marasa lafiya na wannan zamani Galvus Met a cikin ƙaramin adadin don kula da matakin glucose na jini a matakin al'ada.
Ana iya tsara magungunan bayan tabbatar da aikin al'ada na kodan. Dole ne a gudanar da aikin kula da koda a cikin tsofaffin marasa lafiya.
Side effects
Yin amfani da kwayoyi da Galvus Met na iya shafar aikin gabobin ciki da kuma yanayin jikin gaba ɗaya. Abubuwan da aka fi yawan jin labarinsu sune:
- tsananin fushi da ciwon kai;
- rawar jiki;
- jin jin sanyi.
- tashin zuciya tare da amai;
- gastroesophageal reflux;
- ciwo da ciwo mai zafi a cikin ciki;
- rashin lafiyan fata rashes;
- rikice-rikice, maƙarƙashiya da zawo;
- kumburi
- low juriya ga kamuwa da cuta da ƙwayoyin cuta;
- ƙarancin aiki da gajiya mai sauri;
- hanta da cutar koda, alal misali, hepatitis da pancreatitis;
- tsananin peeling na fatar;
- bayyanar blisters.
Abubuwan kwantar da hankali don amfani da miyagun ƙwayoyi
Abubuwan da zasu biyo baya da kuma sake dubawa na iya zama contraindications wa magani tare da wannan magani:
- halayen rashin lafiyan mutum ko rashin haƙuri ga abubuwan aiki na miyagun ƙwayoyi;
- cutar koda, gazawar koda da kuma aiki mara kyau;
- yanayin da zai iya haifar da wahalar aikin keɓaɓɓen, kamar amai, zawo, zazzabi da cututtuka;
- cututtuka na tsarin zuciya da jijiyoyin jini, gazawar zuciya, infarction zuciya na zuciya;
- cututtuka na numfashi;
- ketoacidosis na masu ciwon sukari wanda ya haifar da wata cuta, ko coma, ko jihar predomatous, a matsayin rikicewar cutar sankara. Bayan wannan magani, yin amfani da insulin ya zama dole;
- tara tarin lactic acid a jikin mutum, lactic acidosis;
- ciki da shayarwa;
- nau'in farko na ciwon sukari;
- barasa ko giya mai guba;
- bin wani tsayayyen tsarin abinci, wanda cikin adadin kuzari bai wuce 1000 a kowace rana ba;
- shekaru haƙuri. Ba a ba da shawarar yin amfani da maganin ba ga marasa lafiya da ke ƙasa da shekara 18. Ana ba da shawarar mutanen da suka wuce shekaru 60 su sha maganin a ƙarƙashin kulawar likitoci;
- an dakatar da miyagun ƙwayoyi yana ɗauka kwana biyu kafin a tsara aikin tiyata, karatun rediyo ko gabatarwar bambanci. Hakanan ana bada shawara don guji amfani da miyagun ƙwayoyi na kwanaki 2 bayan hanyoyin.
Tunda lokacin shan Galvus ko Galvus Meta, ɗayan manyan contraindications shine lactic acidosis, to, marasa lafiya da ke fama da cututtukan hanta da kodan kada su yi amfani da waɗannan magungunan don kula da ciwon sukari na 2.
A cikin marasa lafiya fiye da shekaru 60 da haihuwa, hadarin rikice rikice na ciwon sukari mellitus yana ƙaruwa sau da yawa, abin da ya faru na lactic acidosis wanda lalacewa ta hanyar jaraba ga kayan magani - metformin. Sabili da haka, dole ne a yi amfani dashi tare da taka tsantsan.
Amfani da magani yayin daukar ciki da shayarwa
Ba a yi nazarin tasirin maganin a kan mata masu juna biyu ba, don haka ba a ba da shawarar aikinta ga mata masu juna biyu ba.
A cikin yanayin karuwa a cikin matakan glucose na jini na mata masu juna biyu, akwai hadarin kamuwa da cutar mahaifa a cikin yaran, da kuma faruwar wasu cututtuka daban-daban har ma da mutuwar tayi. A cikin yanayin ƙara yawan sukari, ana bada shawara don amfani da insulin don daidaita shi.
Yayin aiwatar da nazarin tasirin miyagun ƙwayoyi akan jikin mace mai juna biyu, an gabatar da wani kashi da ya wuce matsakaicin sau 200. A wannan halin, ba'a gano ci gaban tayin ba ko kuma wasu abubuwa masu girma na haɓaka. Tare da gabatarwar vildagliptin a hade tare da metformin a cikin rabo na 1:10, ba a rubuta abubuwan da suka faru ba a cikin ci gaban tayi.
Hakanan, babu ingantaccen bayanai akan abubuwan da ke cikin magunguna yayin shayarwa tare da madara. A wannan batun, ba a ba da shawarar iyaye mata masu shayar da shan magungunan ba.
Ba a bayyana sakamakon amfani da miyagun ƙwayoyi ta mutane underan shekaru 18 ba. Abubuwan da ba su dace ba game da amfani da miyagun ƙwayoyi ta hanyar marasa lafiyar wannan rukuni ba su ma ba a san su ba.
Amfani da miyagun ƙwayoyi ta hanyar marasa lafiya sama da 60 shekara
Marasa lafiya fiye da shekara 60 saboda haɗarin rikice-rikice ko sakamako masu illa da ke tattare da shan waɗannan magungunan ya kamata su sa ido sosai a kan sashi kuma su sha maganin a ƙarƙashin kulawar likita.
Shawara ta musamman
Duk da gaskiyar cewa ana amfani da waɗannan magungunan don daidaita sukari a cikin sukari na 2, waɗannan ba insulin analogues bane. Lokacin amfani da su, likitoci sun ba da shawarar a kai a kai domin tantance ayyukan ƙwayoyin hanta.
Wannan ya faru ne saboda gaskiyar cewa vildagliptin, wanda shine ɓangare na miyagun ƙwayoyi, yana haifar da karuwa a cikin ayyukan aminotransferases. Wannan gaskiyar ba ta bayyana a kowace alama, amma tana haifar da rikicewar hanta. An lura da wannan yanayin a cikin yawancin marasa lafiya daga rukuni na sarrafawa.
Marasa lafiya waɗanda ke shan waɗannan magunguna na dogon lokaci kuma ba sa amfani da analogues nasu ana ba da shawarar su ɗauki gwajin jini gaba ɗaya sau ɗaya a shekara. Manufar wannan binciken shine gano duk wani karkacewa ko illa da aka samu a matakin farko da kuma daukar matakan da suka dace don kawar dasu.
Tare da tashin hankali mai juyayi, damuwa, zazzabi, sakamakon maganin a kan mai haƙuri zai iya raguwa sosai. Nazarin marasa lafiya suna nuna irin waɗannan sakamako na magunguna kamar tashin zuciya da rashin ƙarfi. Tare da irin waɗannan alamu, ana bada shawara don guji tuki ko yin aikin ƙara haɗari.
Mahimmanci! Awanni 48 kafin kowane nau'in cuta da kuma amfani da wakili, ana bada shawara a daina shan wadannan kwayoyi. Wannan ya faru ne saboda gaskiyar cewa bambancin dake tattare da aidin, a cikin mahadi tare da abubuwan da ke cikin miyagun ƙwayoyi, na iya haifar da mummunan lalacewa a ayyukan koda da hanta. A kan wannan tushen, mai haƙuri na iya haɓaka lactic acidosis.
