Magunguna da aka yi a Rasha don magance cutar hawan jini da rashin karfin zuciya. Wannan aikin ya dogara ne akan jijiyoyin bugun gini. Sakamakon ingantaccen asibiti yana tasowa makonni 2-3 bayan fara magani.
Sunan kasa da kasa mai zaman kansa
Hinapril. Sunan Latin shine Chinaprilum.
Magunguna da aka yi a Rasha don magance cutar hawan jini da rashin karfin zuciya.
ATX
C09AA06
Saki siffofin da abun da ke ciki
Akwai shi ta hanyar Allunan a cikin fim mai rufi tare da sashi na 5,10, 20 ko 40 MG na kayan aiki. A cikin 1 blister - Allunan 10. An saka blisters a cikin kwali na kwali na 3 inji mai kwakwalwa.
Abun da keɓaɓɓen kwamfutar hannu ya haɗa da abu mai aiki tare da sunan magani ɗaya (farin foda, mai narkewa a ruwa) da ƙarin abubuwan haɗin gwiwa - abubuwan da ke ɗaure, fenti, lokacin farin ciki, da sauransu.
Aikin magunguna
Ayyukan maganin sun dogara ne da kaddarorin quinapril don hana exopeptidase don haka rage hadaddun kwayoyin hormones na oligopeptide wanda ke haifar da vasoconstriction.
Sakamakon wannan tasirin, tasoshin yanki suna faɗaɗa, samarda jini ga myocardium bayan ischemia ya inganta, kwararar jini a cikin kodan da tasoshin jijiyoyin jini yana ƙaruwa, juriya ga damuwa na jiki yana ƙaruwa, adadin ƙwayar jijiyoyin jini yana raguwa, hauhawar jini da kuma haɗarin thrombosis.
Pharmacokinetics
Adadin isa ga mafi yawan maida hankali a cikin jini shine awa 1 bayan gudanarwar maganin baka. Aikin yana gudana gwargwadon yawan aikin da aka ɗauka.
Adadin isa ga mafi yawan maida hankali a cikin jini shine awa 1 bayan gudanarwar maganin baka.
Kasancewa daga cikin ciki shine kusan kashi 60%, amma zai iya kassara shi ta hanyar cin abinci guda ɗaya na abinci mai mai mai yawa.
Yana samarda metabolites a cikin hanta, akasari quinaprilat, wanda ke iya ɗaukar nauyin sunadarai na plasma sama da 90%.
An cire ta ta hanjin kodan da hanjin ta.
Alamu don amfani
Ana amfani dashi don monotherapy kuma a haɗe don cututtuka irin su:
- hauhawar jijiyoyin jini (na farko, sake gyara jiki, sakandare da ba a tantance ba);
- gazawar zuciya (buguwa, bugun zuciya, tare da tabarbarewar zuciya, rikicewar bugun zuciya, gazawar zuciya).
Tare da hauhawar jini, gudanarwa na lokaci daya tare da daskararru masu daskarewa na potassium da beta-blockers mai yiwuwa ne, kuma tare da raunin zuciya tare da masu hana jini, da sauransu.
Contraindications
Magungunan yana contraindicated a cikin wadannan lokuta:
- hyperreaction ga abu mai aiki ko ƙarin abubuwan haɗin kwamfutar hannu;
- ciki da lactation;
- yara da matasa (har zuwa shekaru 18);
- kasancewar tarihin cutar ansila;
- mai ciwon sukari mai ciwon sukari;
- rashi mai aiki;
- jijiyoyin jini;
- hyperkalemia
Alƙawarin yana yiwuwa, amma tare da taka tsantsan kuma a ƙarƙashin kulawar ma'aikatan lafiya a yayin kasancewar:
- haɗarin mahaifa;
- atherosclerosis na kafafu;
- mitral valve stenosis;
- katuwar katuwar zuciya tare da canje-canje na jini;
- dasawa da koda;
- rikice-rikice a cikin ƙwayar tsarkakewar ƙwayar jini (gout);
- cututtukan cututtukan nama na autoimmune;
- ciwon sukari mellitus;
- bukatar mTOR da DPP-4 enzyme inhibitors;
- cututtukan da suke hanawa ci gaban cututtukan bronchopulmonary a cikin na kullum.
Zai fi kyau a guji ɗaukar waɗannan allunan a cikin marasa lafiya waɗanda ke da cutar hanta na gaba don guje wa haɓakar cutar hepatic.
Yadda za a ɗauki quinapril?
Kai da baka, ba tare da la'akari da abincin ba. An hadiye kwamfutar hannu ba tare da taunawa ba, an wanke shi da ruwa kaɗan.
Tare da hauhawar jini, monoprint mai yiwuwa ne, kuma a hade tare da sauran jami'ai.
Game da maganin monotherapy, an fara magani tare da sashi na 10 MG sau ɗaya kuma sannu a hankali ya karu zuwa 20 ko 40 MG, dangane da nasarar tasirin asibiti.
Tare da hauhawar jini, monoprint mai yiwuwa ne, kuma a hade tare da sauran jami'ai.
A haɗuwa da jiyya tare da diuretics, daga 5 MG kowace rana ana wajabta sau ɗaya tare da haɓakawa a cikin kwanakin masu zuwa har sai an sami sakamakon da ake tsammanin, amma ba fiye da shawarar yau da kullun ba.
Theara yawan kashi kamar sau ɗaya a wata. Matsakaicin izinin kowace rana bai wuce 80 MG na magani ba.
Rashin ƙarfin zuciya yana buƙatar haɗakar haɗin kai. A wannan yanayin, an fara amfani da miyagun ƙwayoyi tare da 5 MG 1-2 sau a rana, biye da karuwa idan akwai kyakkyawar haƙuri ba fiye da ƙaruwa 1 ba a mako.
Tare da lalataccen aikin na koda, an zaɓi kashi na miyagun ƙwayoyi gwargwadon matakin ƙimar keɓancewar creatinine - mafi girman alamar, mafi girma sashi. Yana yiwuwa a ƙara lamba kawai la'akari da asibiti, kwanciyar hankali na ƙididdigar jini da aikin koda.
Tare da ciwon sukari
A cikin marasa lafiya da masu ciwon sukari mellitus, lokacin ɗaukar wannan magungunan antihypertensive, ana buƙatar kulawa da likita ta yau da kullun tare da zaɓi na adadin da ya dace na maganin ƙwaƙwalwar ƙwayar cuta da Insulin, tun da inganta tasirin su.
Sakamakon sakamako na hinapril
Zai yiwu wasu sakamako masu illa daga cututtukan jini, ƙwayar jijiya ta tsakiya, ƙwayar jijiyoyin jiki da urinary gabobin, narkewa da tsarin jijiyoyin jini, fata, waɗanda galibi ba a bayyana su sosai. Game da shari'o'in 100 na rubutawa, kusan 6% na lokuta na karbowa ana lissafta su.
Wani lokacin akwai cin zarafin numfashi da hangen nesa, raguwa cikin iko, jin zafi a baya da kirji, da dai sauransu.
Gastrointestinal fili
Zai yiwu bayyanar tashin zuciya, amai, dyspepsia, pancreatitis, hepatic coma, hanta necrosis, angioedema na hanji.
Hematopoietic gabobin
Cutar ƙin jini, thrombocytopenia, neutropenia, hyperkalemia, ta ƙara ƙwaƙwalwar creatinine.
Tsarin juyayi na tsakiya
Yawan ciwon kai da yawan zafin zuciya. Wani lokacin paresthesia, ciki da rashin barci suna faruwa.
Daga tsarin urinary
M gazawar koda, cututtukan urinary fili.
A ɓangaren fata
Abubuwan da ke haifar da sakamako ana bayyana su ta hanyar pemphigus, aski, karuwar gumi, ɗaukar hoto, da kuma cututtukan zuciya.
Daga tsarin zuciya
Hypotension, fainting, tashin hankali zuciya, bugun jini, shakatawa na ganuwar tasoshin jini.
Cutar Al'aura
Anaphylactic shock da Quincke na edema mai yiwuwa ne.
Tasiri kan ikon sarrafa abubuwan inji
Ana buƙatar taka tsantsan lokacin tuki da aiki, yana buƙatar mai da hankali sosai, tunda a cikin sakamako masu illa - raguwar hauhawar jini da haushi.
Umarni na musamman
Tare da haɓaka cikin zafin jiki ko ƙwaƙwalwar ƙwayar cuta, yakamata a yi gwajin jini don keɓantar da keɓaɓɓe.
Kafin yin ayyukan tiyata, gami da hakori, dole ne a faɗakar da likitan game da nadin kudaden da aka bayyana a baya.
Yi amfani da tsufa
An yi masu gargadin ne a tsufa saboda ragewar cirewa daga jikin mutum.
Aiki yara
Ba a zartar ba har zuwa shekaru 18.
Tare da taka tsantsan, an wajabta hinapril a cikin tsufa saboda rage kuzarin shi daga jiki.
Yi amfani da lokacin daukar ciki da lactation
A lokacin haila kuma lokacin da ke shayar da yaro, an hana yin amfani da inhibitors na ACE sosai. Tana da ikon wargaza ci gaba kuma ta haifar da mutuwar tayi. Yayin shayarwa, yana iya wucewa cikin madara kuma yana haifar da mummunan sakamako a cikin jariri.
Yawan adadin quinapril
Bayan ɗaukar adadin da ya wuce adadin sashi, raunin gani, rashiwar jiki da tsananin wahala na iya faruwa. An wajabta jiyya a cikin wannan yanayin dangane da alamun.
Yin hulɗa tare da wasu kwayoyi
Inganta sakamako na antihypertensive: narcotic analgesics, shirye-shiryen zinari, maganin motsa jiki, diuretics, ACE inhibitors.
Yana rage tasirin sodium chloride, estrogens, magungunan anti-inflammatory marasa steroidal.
Yana rage sha na tetracycline.
Game da amfani da lokaci daya tare da shirye-shiryen lithium, shan giya na lithium mai yiwuwa ne.
Yana haɓaka aikin insulin da ƙwayoyin hypoglycemic.
Hinapril yana rage sha na tetracycline.
Ba'a bada shawara don haɗaka tare da Aliskiren, immunosuppressants, mTOR ko DPP-4 enzyme inhibitors, har da kwayoyi waɗanda ke hana aikin ɓoye kashi.
Amfani da barasa
Alcohol yana haɓaka sakamako mai hauhawar jini, sabili da haka, amfani da kwanciyar hankali ya haɗu.
Analogs
Hakazalika, allunan da aka saka a cikin fim suna aiki kuma suna da aiki guda ɗaya a cikin abun da ke ciki:
- Accupro - 5,10, 20 ko 40 MG (Jamus).
- Akkuzid - 10 ko 20 MG (Jamus). Hadin magani. Yana da abu na biyu mai aiki - hydrochlorothiazide.
- Hinapril C3 - 5,10, 20 ko 40 MG (Russia).
- Quinafar - 10 MG (Hungary).
Allunan iri daya a cikin kungiyar magunguna:
- Amprilan - 1.25; 2.5; 5 da 10 MG (Slovenia).
- Vasolapril - 10 ko 20 MG (Turkey).
- Diropress - 5, 10 ko 20 mg (Slovenia).
- Captopril - 25 ko 50 MG (Russia, India).
- Monopril - 20 MG (Poland).
- Perineva - 4 ko 8 MG (Russia / Slovenia).
Analogs na iya kasancewa cikin nau'ikan farashin daban-daban.
Magunguna kan bar sharuɗan
Zan iya saya ba tare da takardar sayan magani ba?
Ana fitar dashi ne kawai kan takardar sayen magani daga likitocin da ke halarta.
Farashin Hinapril
Matsakaicin farashin farashin.
Matsakaicin farashin daga 200 zuwa 250 rubles kowace kunshin, ya dogara da sashi.
Yanayin ajiya na miyagun ƙwayoyi
Adana a zazzabi a cikin dakin (ba fiye da + 25ºC) a cikin wani wuri mai duhu ba, daga isa ga yara da dabbobi.
Ranar karewa
Rayuwar shelf tsawon shekaru 3 daga ranar samarwa kuma bayan ranar karewa dole ne a zubar dashi.
Mai masana'anta
An sanya shi a Rasha a kamfanin magunguna ZAO Severnaya Zvezda.
Hinapril Reviews
Likitoci
Irina, likita iyali, Tver
Na wajabta wa marasa lafiya da ke fama da hauhawar jini a jijiya bayan tattara wani abu da kuma cikakken bincike. Sau da yawa nakan haɗa tare da diuretics bisa ga alamu. Magungunan yana da tasiri, amma koyaushe ya kamata ka nemi kasancewar contraindications ga kowane mutum, tunda cutarwa mai haɗari mai yiwuwa ne.
Sergey, likitan zuciya, Astrakhan
A cikin rauni na zuciya, irin wannan magani yana ba da taimako na gaggawa, amma kafin alƙawarin, ya kamata koyaushe ku gudanar da bincike kuma kuyi nazarin tarihin likita.
Marasa lafiya
Anna, shekara 52, Volgograd
Ina shan kwayoyin hana daukar ciki kamar yadda likitana ya umarta a matsayin kayan tallafi don hauhawar jini. Daga cikin tasirin sakamako, kawai zan iya ɗan ɗanɗana nutsuwa a farkon jiyya.
Sofiya, 39 years, Vologda
Ba a daɗe ba, matsalolin matsin lamba sun fara. Na je wurin likitan ilimin likitanci kuma a can, bayan gwajin, an tsara waɗannan magungunan. Yanzu matsin lamba kusan koyaushe al'ada ne, sai dai a lokuta masu tayar da hankali, kuma ba a lura da wani mummunan sakamako mai illa.
