Gliclazide - cikakkun bayanai don amfani, sake dubawa game da masu ciwon sukari da likitoci

Mellitus-non-insulin-dogara da ciwon sukari shine mafi yawan nau'in cutar (90-95% na duk lokuta na ciwon sukari). Gudanarwa mai inganci na cututtukan ƙwayar cuta yana buƙatar ba kawai gyare-gyare na rayuwa ba, har ma da magani na yau da kullun. Abubuwan da aka samo na sulfonylurea (SM) Hakanan suna cikin jerin magunguna masu mahimmanci ga masu ciwon sukari, wanda shine ɗayan zaɓaɓɓen magani na shahararrun magunguna don kowane nau'in algorithm.

Babban inganci tare da kyawun haƙuri da ƙarancin tattalin arziki da aka ba da izinin dogon lokaci don amfani da abubuwan da aka kirkira na SM a matsayin babban aji na wakilai na maganin ƙwaƙwalwar ƙwayar cuta, kiyaye su a cikin hanyoyin kwantar da hankali ko da sauyawa zuwa insulin.

Kyakkyawan maganin antidiabetic a yau yakamata ya zama mai sauƙi don gudanarwa, tare da ƙarancin haɗarin sakamako masu illa (kuma ba kawai hypoglycemia) ba, mai saukin rahusa, dogara da inganci. Ya cika dukkan waɗannan buƙatu Gliclazide (a Latin Gliclazide) magani ne na asali na ɗimbin CM.

Pharmacology Glycaside

Gliclazide, hoto wanda za'a iya gani a wannan sashin, magani ne wanda ke wakiltar aji na abubuwan asalin SM na mutanen 2.

Babban (amma ba kawai) tasirin maganin shine hypoglycemic: yana haɓaka samar da insulin endogenous ta ƙwaƙwalwar ƙwayar ƙwayar ƙwayar cuta. Ta hanyar ƙarfafa tsokawar glycogen synthase, gliclazide yana inganta amfani da glucose na tsoka. A miyagun ƙwayoyi dawo da glycemic sigogi da sauri, tare da tare da na rayuwa latent ciwon sukari.

Daga karɓar abinci a cikin narkewa har zuwa lokacin samar da insulin tare da allunan, ƙarancin lokaci yakan wuce yadda ba tare da su ba. Hyperglycemia, wanda tsokanar ya haifar da carbohydrates, tare da gliclazide bashi da lahani.

Pharmacokinetics na miyagun ƙwayoyi

Daga narkewa, ana shan maganin nan take kuma ya cika. An cimma matakin ganiya a cikin kewayon daga awa 2 zuwa 6, kuma ga allunan da ke da tasirin zamani - daga 6 zuwa 12 hours. Tsawon lokacin bayyanuwa kwana ɗaya ne. Tare da kariyar jini, magani yana da alaƙa da 85-99%. Magungunan yana biotransformed a cikin hanta, yana samar da metabolites, ɗayan wanda yana tasiri microcirculation.

An tsaida rabin rabin rayuwa a cikin kewayon 8-12. A cikin Gliclazide MV - awanni 12-16. A lokaci guda, an cire kashi 65% na maganin a cikin hanyar metabolites a cikin fitsari, 12% ta cikin hanji.

Yaushe aka tsara maganin?

An tsara maganin don sarrafa kwayar cutar glycemic na nau'in ciwon sukari na 2, duka biyu a matsayin monotherapy kuma don haɗuwa da magani tare da sauran magungunan maganin ta baki ko shirye-shiryen insulin.

Umarnin Gliclazide don amfani kuma yana bada shawarar yin amfani dashi azaman ɓangaren hadaddun don warkar da cututtukan ƙwayoyin cuta. Don dalilan rigakafin, an tsara magani don hana ci gaban rikitarwa daga cututtukan fata - retinopathy, neuropathy, nephropathy, bugun jini da bugun zuciya.

Contraindications don Gliclazide

Jerin contraindications ya shafi ba kawai ga Glyclazide ba, har ma da dukkanin analogues ɗin (tare da haɗin gwiwa na gama gari na kowa).

Daga cikin abubuwanda aka hana:

• Nau'in cuta guda 1;
• Ketoacidosis (nau'in ciwon sukari);
• Hypersmolar ko ciwon sukari;
• Rashin hankali ga abubuwan da ke cikin tsari;
• Cututtukan hepatic da na koda;
• Rauni mai rauni;
• Leukopenia;
• Hyper- da hypothyroidism;
• Matsewar hanji;
• Paresis na ciki;
• Cututtukan tare da rashi mai narkewar abubuwan gina jiki.

Abun hani na aikace-aikace

Iyakar abin da aka ƙuntata shine shekarun yara, tunda aminci da tasiri ga wannan rukuni na marasa lafiya ba a kafa su ba.

A wasu yanayi na cututtukan cututtukan jini (wanda aka shirya tiyata, karatun radiopaque), ana buƙatar sauyawa ta wucin gadi zuwa insulin (yawanci 48 hours kafin da 48 sa'o'i bayan hanyar)

Hanyar kulawa tare da miyagun ƙwayoyi yana contraindicated lokacin daukar ciki, kuma idan magani ya faru a lokacin lactation, yaro an canza shi zuwa abinci mai wucin gadi.

Side effects

Kwanan nan, wallafe-wallafe sun bayyana a Turai da Amurka game da alaƙar da ake zargi tsakanin gudanarwar abubuwan da aka samo asali na SM tare da shirye-shiryen insulin da kuma yiwuwar cututtukan cututtukan cututtukan cututtukan fata da cututtukan cututtukan daji. Bayanin da ba a tabbatar da shi ba, tunda gliclazide shine magani na asali, an gudanar da binciken lafiya sosai.

Cikakken jerin sakamakon da ba a tsammani ba yana cikin tebur.

Sakamakon haɗarin yanayin hypoglycemic, kar a sanya Gliclazide a cikin tsofaffi masu ciwon sukari tare da rashin abinci mai gina jiki da kuma rashin goyon bayan zamantakewa, musamman tare da cututtukan zuciya da cututtukan fata.

Abun Harkokin Magunguna

Gliclazide yana iya haɓaka inhibitors na ACE, magungunan anabolic, β-blockers, Fluxidine, cimetidine, salicylates, miconazole, MAO inhibitors, fluconazole, theophylline, pentoxifylline, tetracyclines.

Tasirin glycoside ya raunana tare da amfani da layi daya na amfani da barbiturates, glucocorticoids, sympathomimetics, saluretics, maganin hana haihuwa, rifampicin, estrogens.

Yadda ake nema

Ana ɗaukar Glycloside a baki tare da abinci. An cinye kwamfutar hannu gaba ɗaya, ba tare da murƙushewa ba, an wanke shi da ruwa. Likita zai zabi allurai daban-daban, yin la’akari da matakin cutar da kuma yadda masu ciwon sukari ke maganin. Tsarin farawa yawanci baya wuce 80 MG, idan ba shi da isasshen ƙarfi, ƙwaƙwalwar a hankali tana ƙaruwa.

Ka'idojin yau da kullun sun tashi daga MG 30 zuwa 120 MG, la'akari da matakin cutar sankara da ƙuntatawa na shekaru. A wasu yanayi, har zuwa 320 MG na iya sawa.

Idan an rasa lokacin liyafar, ba za ku iya ninka biyu ba. Ya kamata a sha magungunan a farkon damar.
Yin amfani da daidaitattun haɗuwa yana yiwuwa ba kawai tare da metformin ba, wanda kawai ake amfani dashi fiye da wakilan SM, amma kuma tare da tsauraran matakan sau uku.

Karin kumallo, wanda yake ɗaukar maganin, ya kamata ya zama cikakke, tare da mafi ƙarancin adadin carbohydrates. Matsalar yunwa a lokacin rana, musamman tare da cunkoso na jiki, na iya haifar da hauhawar jini. Halin iri ɗaya yana yiwuwa bayan shan barasa.

Masu ciwon sukari a cikin balagaggu suna kula sosai da Glyclazide, tunda suna da yiwuwar haɓaka cutar glycemia. Wannan rukuni na marasa lafiya ya fi dacewa da magunguna na gajeren lokaci kamar glycazide na yau da kullun.

Allunan-saki allunan aiki a ko'ina cikin yini, haka ma, gudanar da irin wannan magani ne guda. Sashi na Gliclazide MV shine rabi na daidaitaccen sigar. Magungunan suna da tasiri don shekaru 3-5, to, yiwuwar juriya yana ƙaruwa - wani ɓangare ko cikakken rashin ingancinsa. A irin waɗannan halayen, endocrinologist yana canza tsarin kulawa.

Magunguna na asali, kamar ƙwayoyinta, suna tasiri ne kawai a cikin gyaran rayuwa - ƙarancin abinci mai narkewa, wadataccen aiki na yau da kullun, kula da yanayin motsin rai, da lura da yanayin bacci da hutawa.

Daidai da mahimmanci shine saka idanu a cikin rana tare da yin rikodin sakamako a cikin diary na masu ciwon sukari. Bayan matsananciyar damuwa, yawan aiki na jiki, rashin abinci mai gina jiki, ƙaddamar da sashi na iya zama dole. Kula da yanayinka da kasancewa tare da likitanka na yau da kullun zasu taimaka wajen kaucewa mummunan sakamako.

Matakan hanyoyin kariya

Don rigakafin hare-haren hypoglycemic, yana da muhimmanci a sami karin kumallo bayan kwaya, hana yunwar rana, da kuma ware barasa daga abincin. Amfani mai amfani da b-blockers na iya rufe alamun bayyanar cututtuka na hypoglycemic. Yana da mahimmanci ga masu ciwon sukari su bi ƙananan abincin carb.

Taimaka wa wanda aka cutar da abin ya wuce kima

Idan halatta izini yana wuce mahimmanci, alamun ƙarin yawan abin sha zai iya bayyana:

1. Jin gajiya;
2. Inara cikin hawan jini;
3. Ciwon kai;
4. Rashin tausayi, haushi;
5. An hana amsawa;
6. Rashin gani na ɗan lokaci;
7. Rashin ayyukan ayyuka;
8. Ragewa;
9. Kasawa.

   
   

Idan glycemia ya dauki mummunan yanayi kuma wanda aka azabtar ba ya kula da yanayinsa, yana buƙatar asibiti da gaggawa. Don dakatar da harin a cikin sa'o'i na farko, wajibi ne don allurar 50 na glucose (30% r) a cikin jijiya da ruwa - dextrose (10% r) a cikin jijiya. Yana da mahimmanci a farkon kwanakin don saka idanu a kan glycemia a kai a kai. Binciko tare da yawan yawan gliclazide ba shi da tasiri.

Sashi tsari da abun da ke ciki

Game da mamayar, shirye-shiryen SM sune na biyu kawai ga Metformin. Daya daga cikin fa'idodin magani shine kasancewarsa: don Gliclazide, farashin a cikin sarkar kantin magani bai wuce 160 rubles ba. don 30 inji mai kwakwalwa. A cikin cibiyar sadarwar kantin magani, ana ba da magani a ƙarƙashin sunayen cinikayya daban-daban: Glyclazide-Akos, Glyclazide Canon, Glidiab-MV. An samar da maganin a cikin nau'ikan daban-daban, akwai zaɓi tare da sakin ingantaccen sashin ginin.

Allunan suna da ɗanɗano mai kirim da ɗan marbling. A cikin sel na farantin aluminium na iya zama 10, 20 ko 30 inji mai kwakwalwa. kwayoyin hana daukar ciki. An saka blister a cikin kwalaye 10, 20, 30, 60 har ma allunan 100.

Kowane kwamfutar hannu yana dauke da gliclazide wanda ke aiki mai ƙarfi, wanda aka haɗaka tare da cellulose, hypromellose, silloon silicon dioxide, magnesium stearate.

Bambanci tare da tasirin rikicewar Glycaside MV ana siyar da shi a cikin fakitin 15 ko 30 a cikin gilashi ko akwatin.

Babban mahimmancin wannan aji na kwayoyi shine alama ta yiwuwar haɓaka juriya: bisa ga ƙididdiga, 5% na masu ciwon sukari waɗanda ke ɗaukar tsinkayen SM don dogon lokaci don canzawa zuwa insulin na tsawon lokaci.

Jeneric Glyclazide

Gliclazide - asalin magani, duk sauran magunguna tare da abu ɗaya mai aiki ko tasirin magani, analogues. Glidiab ya mallaki mafi kyawun farashi da inganci tsakanin Gliclazide analogues wanda farashinsa ya kai 111-137 rubles. Ana bayar da yabo ga likitoci ta hanyar magungunan Diabeton da Diabeton MV. Farashin magunguna daga 250 zuwa 320 rubles.

Daga cikin wasu magungunan da suka dace da lambar 4 na ATX, mafi shahararrun sune:

• Glurenorm;
• Glimepiride;
• Amix;
• Glibenclamide;
• Amaryl;
• Maninil.

Idan bayan rubanya sabon Glyclazide, abubuwan da ba a fahimta da yawa sun bayyana, bayar da rahoton rashin jin daɗi ga likitanka. Wataƙila, bayan ƙarin jarrabawa, zai rage kashi ko zaɓi ƙirar da ta dace. Yin gwaje-gwaje tare da ƙwayoyin halittar kanka yana da haɗari ga lafiyar ku.

Gliclazide - sake dubawa game da masu ciwon sukari da likitoci

Hanyar da zazzagewa na zamani na nau'in ciwon sukari na 2 ya kamata a daidaita shi daban-daban, "wanda aka daidaita" don bukatun wani mai haƙuri, ya kamata yayi la'akari da shekarunsa da sifofin asibiti don rage nakasa, zuwa ga canjin yanayin dogon lokaci na cutar kuma ya tsawaita rayuwar mai cutar.

Tabbas, Glyclazide bai dace da kowa ba, har ma da sauran wakilai masu rage sukari, amma ana iya jayayya cewa magungunan da analogues ɗin su sun cika daidai da ƙa'idodin zamani da aka bayyana, suna dacewa kuma suna ci gaba da taimakawa masu ciwon sukari yadda yakamata su magance cutar ta rashin hankali.

Game da maganin likita na ciwon sukari nau'in nau'in goth 2 akan bidiyo