Insulin NovoMiks - wani magani ne wanda yake kunshe da analogues na kwayar halittar sukari-mutum. Ana amfani dashi a cikin lura da ciwon sukari na mellitus, duka-insulin-dogara da nau'in-insulin-dogara. A lokacin guna, cutar ta bazu a duk kusurwar duniyar, yayin da 90% na masu ciwon sukari ke fama da cutar ta biyu, ragowar 10% - daga tsari na farko.
Injections na insulin suna da mahimmanci, tare da isasshen sarrafawa, abubuwan da ba a iya warwarewa a jiki har ma mutuwa ta faru. Saboda haka, kowane mutum da ke dauke da cutar sankarau na ciwon suga, danginsa da abokan sa suna bukatar su “dauke da makamai” tare da sanin kwayoyi game da cututtukan jini da na insulin, da kuma yadda ya dace.
Hanyar aiwatar da maganin
Ana samun insulin a cikin Denmark a cikin nau'in dakatarwa, wanda ko dai a cikin kundin 3 ml (NovoMix 30 Penfill) ko a cikin allon syringe 3 ml (NovoMix 30 FlexPen). Dakatarwar ta zama fari fari, wani lokacin samuwar flakes mai yiwuwa ne. Tare da ƙirƙirar farin precipitate da wani translucent ruwa a samansa, kawai kuna buƙatar girgiza shi, kamar yadda aka fada a cikin umarnin da aka haɗe.
Abubuwan da ke aiki na miyagun ƙwayoyi suna narkewa kamar insulin (30%) da lu'ulu'u, har da insulin aspart protamine (70%). Bayan waɗannan abubuwan haɗin, ƙwayar ta ƙunshi ƙananan adadin glycerol, metacresol, sodium hydrogen phosphate dihydrate, chloride zinc da sauran abubuwa.
Minti 10-20 bayan gabatarwar miyagun ƙwayoyi a ƙarƙashin fata, yana fara tasirin hypoglycemic. Insulin aspart yana ɗaure wa masu karɓa na hormone, don haka glucose ta keɓaɓɓe ta hanyar sel kuma ta hana haɓaka daga hanta aukuwa. Ana lura da mafi girman tasirin insulin bayan awa 1-4, kuma tasirinsa ya wuce awanni 24.
Nazarin ilimin magunguna yayin hada insulin tare da magunguna masu rage sukari na masu ciwon sukari irin na II sun tabbatar da cewa NovoMix 30 a hade tare da metformin yana da tasiri mai girma na hypoglycemic fiye da haɗuwa da maganin sulfonylurea da abubuwan samuwar metformin.
Ko yaya, masanan kimiyya ba su gwada tasirin maganin a kan ƙananan yara ba, mutanen da suka manyanta kuma suna fama da cututtukan hanta ko koda.
Umarnin don amfani da miyagun ƙwayoyi
A takaice, likita yana da hakkin ya tsara daidai gwargwadon insulin, la'akari da matakin glucose a cikin jinin mai haƙuri. Ya kamata a tuna cewa ana amfani da miyagun ƙwayoyi a cikin nau'in cutar ta farko kuma idan akwai rashin inganci a cikin nau'in na biyu.
Ganin cewa hormone na biphasic yana aiki da sauri fiye da hormone mutum, ana yin shi sau da yawa kafin cin abinci, kodayake yana yiwuwa a sarrafa shi jim kaɗan bayan an cika shi da abinci.
Matsakaicin mai nuna alamar buƙatar mai ciwon sukari a cikin hormone, dangane da nauyinsa (a cikin kilo), raka'a 0.5-1 na aiki kowace rana. Yawan magani na yau da kullun na iya ƙaruwa tare da marasa lafiya marasa hankali ga hormone (alal misali, tare da kiba) ko rage lokacin da mai haƙuri yana da wasu ajiyar insulin da aka samar. Zai fi kyau allurar a cikin cinya, amma kuma yana yiwuwa a yankin ciki na gwiwa ko kafada. Ba a ke so a saka shi a wuri ɗaya ba, har a cikin yanki ɗaya.
Ana iya amfani da insulin NovoMix 30 FlexPen da NovoMix 30 Penfill azaman babban kayan aiki ko a hade tare da sauran magungunan hypoglycemic. Lokacin da aka haɗu da metformin, kashi na farko na hormone shine raka'a 0.2 na aiki da kilogram kowace rana. Likita zai iya yin lissafin adadin wadannan kwayoyi guda biyu bisa lamuran alamu na glucose a cikin jini da kuma halayen mai haƙuri. Ya kamata a sani cewa koda koda ko kuma hanta na iya haifar da raguwa a cikin buƙatar mai ciwon sukari a cikin insulin.
NovoMix ana gudanar da shi kawai a ƙarƙashin ƙasa (ƙarin bayani game da algorithm don gudanar da insulin subcutaneously), an haramta shi sosai don yin allura a cikin ƙwayar tsoka ko cikin jijiya. Don guje wa samuwar ƙwayar cuta, ya zama dole sau da yawa don canza wurin allurar. Za'a iya yin allurar cikin duk wuraren da aka nuna a baya, amma tasirin maganin yana faruwa sosai a farkon lokacin da aka gabatar da shi a cikin kugu.
An adana maganin don ruhun shekarun daga ranar saki. Wani sabon bayani wanda ba a amfani dashi a cikin gwal ko alƙalin sirinji ana adana shi a cikin firiji daga digiri 2 zuwa 8, kuma ana amfani dashi a zazzabi ɗakin ƙasa da kwanaki 30.
Don hana fitowar rana, saka maɓallin kariya a alƙalin sirinji.
Contraindications da sakamako masu illa
NovoMix kusan babu maganin hana haihuwa sai dai don rage saurin hauhawar sukari ko karuwar kamuwa da kowane irin kayan da ke ciki.
Ya kamata a sani cewa yayin haihuwar jaririn, ba a sami sakamako masu illa ba a kan mahaifiyar da ke ɗanta da ɗanta.
Lokacin shayarwa, ana iya gudanar da insulin, tunda ba a yada shi ga jariri tare da madara. Amma duk da haka, kafin amfani da NovoMix 30, mace tana buƙatar tuntuɓi likita wanda zai ba da magunguna masu lafiya.
Amma game da yiwuwar cutar da ƙwayar cuta, an fi dacewa da girman sashi. Sabili da haka, yana da matukar muhimmanci a gudanar da maganin da aka tsara, lura da duk shawarar likita. Matsaloli da ka iya haifar sun hada da:
- Halin hypoglycemia (ƙarin bayani game da abin da keɓaɓɓen rashin lafiya a cikin ciwon sukari na mellitus), wanda ke tattare da asarar hankali da kuma rauni.
- Harshe a kan fata, urticaria, itching, sweating, halayen anaphylactic, angioedema, ƙara yawan palpitations da ƙananan karfin jini.
- Canja wurin shakatawa, wani lokacin - ci gaban retinopathy (raguwar tasoshin retina).
- Liyst dystrophy a wurin allurar, kazalika da jan ciki da kumburi a wurin allurar.
A cikin lokuta na musamman, saboda rashin haƙuri na mai haƙuri, ƙarin yawan abin sha zai iya faruwa, alamun abin da ya bambanta, ya danganta da tsananin yanayin. Alamar cutar rashin karfin jini shine nutsuwa, rikicewa, tashin zuciya, amai, tachycardia.
Tare da yawan abin sama da ya kamata, mai haƙuri yana buƙatar cin samfurin da ya ƙunshi adadin sukari mai yawa. Wannan na iya zama kuki, alewa, ruwan 'ya'yan itace mai zaki, yana da kyau a sami wani abu a wannan jeri. Doaƙƙar yawan zubar da jini yana buƙatar gudanar da aikin glucagon nan da nan ƙarƙashin ƙasa, idan jikin mai haƙuri bai amsa allurar glucagon ba, mai kula da lafiyar dole ne ya jagoranci glucose.
Bayan daidaita yanayin, mai haƙuri yana buƙatar cinye sauƙin carbohydrates mai sauƙin digo don hana maimaita yawan kumburi.
Yin hulɗa tare da wasu magunguna
Lokacin gudanar da allurar insulin NovoMix 30, yakamata a ba da mahimmanci ga cewa wasu kwayoyi suna da tasiri ga tasirin hypoglycemic.
Alkahol yafi ƙaruwa sakamakon sukari-na rage yawan insulin, da kuma beta-adrenergic blockers mask alamun yanayin rashin ƙarfi na hypoglycemic.
Ya danganta da magungunan da aka yi amfani dasu a hade tare da insulin, ayyukanta duka zasu iya ƙaruwa da raguwa.
An lura da rage girman buƙatun homon yayin amfani da waɗannan kwayoyi:
- magungunan cikin gida na hypoglycemic;
- monoamine oxidase inhibitors (MAO);
- angiotensin mai canza enzyme (ACE) hanawa;
- marasa zaɓi na beta-adrenergic blockers;
- octreotide;
- magungunan anabolic steroids;
- salicylates;
- sulfonamides;
- giya sha.
Wasu kwayoyi suna rage ayyukan insulin kuma suna ƙaruwa game da haƙuri. Irin wannan tsari yana faruwa lokacin amfani:
- kwayoyin hodar iblis;
- glucocorticoids;
- m
- danazole da thiazides;
- contraceptives shan cikin.
Wasu kwayoyi ba su dace da insulin NovoMix ba. Wannan shi ne, da farko, samfuran da ke ɗauke da thiols da sulfites. Hakanan an hana magungunan karawa zuwa cikin maganin jiko. Yin amfani da insulin tare da waɗannan magunguna na iya haifar da mummunan sakamako.
Farashi da magunguna
Tun da aka samar da magani a ƙasashen waje, farashinsa ya yi yawa. Za'a iya siye ta tare da takardar sayan magani a cikin kantin magani ko kuma ana yin odar layi akan gidan yanar gizon mai siyarwa. Kudin maganin ya dogara da ko maganin yana cikin katunin katako ko sirinji da wanne kunshin. Farashin ya bambanta don NovoMix 30 Penfill (katako 5 a kowace fakitin) - daga 1670 zuwa 1800 rubles na Rasha, kuma NovoMix 30 FlexPen (alkalami 5 na siket a kowace fakitin) yana da farashi a cikin kewayon daga 1630 zuwa 2000 Rasha rubles.
Nazarin yawancin masu ciwon sukari da suka allurar da kwayoyin halittar biphasic suna da inganci. Wasu sun ce sun sauya zuwa NovoMix 30 bayan sun yi amfani da wasu insulins na roba. Dangane da wannan, yana yiwuwa a nuna irin wannan fa'idodin na miyagun ƙwayoyi a matsayin sauƙin amfani da raguwa a cikin yiwuwar yanayin hypoglycemic.
Bugu da kari, kodayake maganin yana da jerin abubuwanda zasu iya haifarda mummunan sakamako, amma basu da sauki. Saboda haka, NovoMix ana iya ɗauka magani mai nasara gaba ɗaya.
Tabbas, akwai sake dubawa wanda a wasu yanayi bai dace ba. Amma kowane magani yana da contraindications.
Haka magunguna
A cikin yanayin inda magani bai dace da mai haƙuri ba ko haifar da sakamako masu illa, likitan halartar na iya sauya tsarin kulawa. Don yin wannan, yana daidaita sashi na magani ko ma ya soke amfani dashi. Sabili da haka, akwai buƙatar amfani da magani tare da tasirin hypoglycemic mai kama.
Ya kamata a lura cewa shirye-shiryen NovoMix 30 FlexPen da NovoMix 30 Penfill ba su da analogues a cikin ɓangaren aiki - insulin aspart. Likita na iya tsara wani magani wanda yake da irinsa.
Ana sayar da waɗannan magunguna ta takardar sayan magani. Sabili da haka, idan ya cancanta, maganin insulin, dole ne mai haƙuri ya nemi likita.
Magunguna waɗanda ke da tasirin irinsu sune:
- Humalog Mix 25 shine analog na roba na kwayar halittar jikin mutum. Babban kayan shine insulin lispro. Hakanan magani yana da ɗan gajeren sakamako ta hanyar daidaita matakan glucose da metabolism. Wani farin dakatarwa ne, wanda aka saki a cikin sirinjirin da ake kira Quick Pen. Matsakaicin farashin magani (maganin sirinji 5 na 3 ml kowane) shine 1860 rubles.
- Himulin M3 wani abu ne na matsakaici wanda aka saki a cikin fitarwa. Ofasar asalin maganin shine Faransa. Abubuwan da ke aiki da miyagun ƙwayoyi shine insulin biosynthetic ɗan adam. Yana iyakance rage yawan glucose a cikin jini ba tare da haifar da farawar hawan jini ba. A cikin kasuwar magunguna na Rasha, ana iya siyan nau'ikan magunguna, kamar Humulin M3, Humulin Regular ko Humulin NPH. Matsakaicin farashin maganin (maganin sirinji 5 na 3 ml) shine 1200 rubles.
Magungunan zamani sun haɓaka, yanzu allurar insulin buƙatar buƙatar yin onlyan lokuta kawai a rana. Alƙalumman da suka dace na alƙawarin sun sauƙaƙa wannan hanyar sau da yawa akan lokaci. Kasuwancin magunguna yana ba da zaɓi mai yawa na insulins na roba. Ofaya daga cikin sanannun kwayoyi shine NovoMix, wanda ke rage matakan sukari zuwa dabi'un al'ada kuma baya haifar da hypoglycemia. Amfani da yakamata, daidai da abinci da aiki na jiki zai tabbatar da rayuwa mai tsawon rai da rashin azama ga masu cutar siga.
