Metformin magani ne wanda masana'antun ke samarwa ta hanyar Allunan suna da adadin milligram na babban bangaren aiki.
A cikin kasuwar magunguna, an gabatar da magunguna suna da babban aiki mai ƙarfi na 500, 850 MG da 1000 MG.
All Allunan tare da 500, 850 mg da 1000 MG sun bambanta a tsakanin su ba kawai a cikin adadin sinadaran da ke aiki ba.
Kowane nau'in kwamfutar hannu ya kamata ya bambanta a tsakanin su ta hanyar zane-zane a saman maganin.
Abun da miyagun ƙwayoyi da kwatancinsa
Allunan suna da babban ma'aunin babban aiki na 500 MG suna da farin ko kusan farin launi. Fuskokin waje na miyagun ƙwayoyi an rufe su da membrane fim, wanda ke da zanen "93" a gefe ɗaya na maganin kuma "48" a ɗayan.
Allunan kwalaben kwalaji 850 sune kayan aiki masu kyau. A saman harsashi, "93" da "49" an zana su.
Magungunan, yana da taro na 1000 MG, yana da kyau a siffar kuma an rufe shi da murfin fim tare da aikace-aikacen haɗari a duk bangarorin biyu. Bugu da kari, abubuwanda aka zana a jikin kwalin: “9” zuwa hagu na hadarin da “3” zuwa dama na hadarin a gefe daya da “72” zuwa hagun hadarin da “14” zuwa dama na hadarin a daya bangaren.
Babban sashin maganin yana maganin metformin hydrochloride.
Baya ga babban bangaren, abun da ya hada magungunan ya hada da masu taimako, kamar:
- povidone K-30;
- povidone K-90;
- silikion dioxide colloidal;
- magnesium stearate;
- hypromellose;
- titanium dioxide;
- macrogol.
Magungunan an yi nufin amfani da shi ne na baki kuma yana cikin rukunin biguanides.
Ofasar asalinsu Isra’ila.
Pharmacodynamics da kuma magunguna na magunguna
Yin amfani da Metformin yana taimakawa rage rage yawan sukari a cikin jini na nau'in na biyu. Rage yawan maida hankali yana faruwa ne sakamakon hana ƙwayoyin jini na gluconeogenesis a cikin ƙwayoyin hanta da kuma ƙaruwa da sinadarin bioprocesses na yin amfani da shi a cikin sel da keɓaɓɓun kyallen takarda. Wadannan kyallen takarda an kwantar da tsoka da adipose.
Magungunan ba shi da wani tasiri a cikin hanyoyin samar da sinadarin insulin a cikin kwayoyin beta na pancreatic. Yin amfani da miyagun ƙwayoyi ba ya tsoratar da faruwar haɗarin hypoglycemic. Yin amfani da miyagun ƙwayoyi yana shafar ƙwayoyin cuta wanda ke faruwa yayin metabolism na lipid, ta hanyar rage abun ciki na triglycerides, cholesterol da ƙarancin lipoproteins mai yawa a cikin ƙwayar jini.
Metformin yana da tasirin ƙarfafawa akan tafiyar matakai na glycogenesis. Sakamakon aiki a cikin ƙwayar intracellular glycogenesis shine kunnawa na glycogenitase.
Bayan miyagun ƙwayoyi sun shiga cikin jikin, Metformin an kusan tallata shi cikin jini daga cikin jijiyoyin mahaifa. A bioavailability na miyagun ƙwayoyi jeri daga 50 zuwa 60 bisa dari.
Matsakaicin ƙwayar aiki yana aiki cikin jini plasma 2.5 sa'o'i bayan shan magani. Makonni 7 bayan shan magani, sha daga cikin aiki mai narkewa daga cikin lumen narkewa cikin jini yana daina aiki, sannan kuma yawan tattara magunguna a cikin jini zai fara raguwa a hankali. Lokacin shan magani tare da abinci, tsarin sha yana rage gudu.
Bayan shiga cikin filayen, metformin baya daure wa hadaddun gida tare da sunadaran a karshen. Kuma da sauri rarraba cikin jikin kyallen takarda.
Drawace maganin yana gudana ta amfani da kodan. Metformin an cire shi daga jiki. Rabin rayuwar miyagun ƙwayoyi shine 6.5 hours.
Manuniya da contraindications don amfani da miyagun ƙwayoyi
Alamar amfani da miyagun ƙwayoyi ta Metformin mv shine kasancewar kamuwa da cutar siga a cikin mutum, wanda bazai iya rama shi ba ta hanyar amfani da abinci da aikin jiki.
Za'a iya amfani da Metformin mv Teva duka biyu a cikin aiwatar da maganin monotherapy, kuma azaman ɗayan abubuwan haɗin gwiwa a cikin halayen ilmin kwantar da hankali.
Lokacin gudanar da rikicewar jiyya, ana iya amfani da wasu wakilai na hypoglycemic don maganin baka ko insulin.
Babban contraindications don shan miyagun ƙwayoyi sune masu zuwa:
- Kasancewar rashin hankalin zuwa ga babban aikin kwayar cutar ko kuma abubuwanda take taimakawa.
- Mai haƙuri yana da ketoacidosis masu ciwon sukari, precoma mai ciwon sukari ko coma.
- Paarancin aiki na haya ko gazawa.
- Ci gaban m yanayin, lokacin da bayyanar take hakkin a cikin aiki da kodan mai yiwuwa ne. Irin waɗannan yanayi na iya haɗawa da rashin ruwa da ruwa.
- Kasancewar a cikin jikin bayyanannun bayyanannun cututtukan cututtuka na yau da kullun wanda zai iya tayar da bayyanar da hypoxia na nama.
- Gudanar da tasoshin aikin tiyata.
- Mai haƙuri yana da gazawar hanta.
- Kasancewar rashin shan giya a cikin mara lafiya.
- Jihar lactic acidosis.
- Ba'a ba da shawarar yin amfani da miyagun ƙwayoyi awanni 48 kafin da kuma awanni 48 bayan gwaje-gwaje da aka gudanar ta amfani da abubuwan kwantar da aidin.
- Ba bu mai kyau amfani da miyagun ƙwayoyi awanni 48 kafin da kuma awanni 48 bayan tiyata, wanda ke tattare da yin amfani da maganin sa barci na gaba daya.
Baya ga waɗannan yanayi, ba a amfani da miyagun ƙwayoyi a ƙarƙashin rage cin abincin carb kuma idan mai haƙuri da ke fama da cutar sankara ya kasa shekaru 18 da haihuwa.
An haramta yin amfani da miyagun ƙwayoyi don amfani da ita lokacin da take haihuwar yara ko yayin shayarwa.
Lokacin da ake shirin yin ciki, ana maye gurbin Metformin MV Teva ta insulin kuma mellitus na sukari yana cikin insulin therapy. A lokacin haila da lokacin shayarwa, mai haƙuri yana ƙarƙashin kulawar likita.
Idan ya zama dole a sha maganin yayin shayarwa, to ya zama dole a daina shayar da nono.
Umarnin don amfani da miyagun ƙwayoyi
A cikin shirya magungunan Metformin Teva, umarnin ya cika kuma ya yi bayani dalla-dalla ga ka'idodin shigar da magani, wanda aka ba da shawarar shigar da magani.
Ya kamata a sha miyagun ƙwayoyi a lokacin abinci ko kuma nan da nan bayan shi.
Shafin farko da aka ba da shawarar maganin na iya, gwargwadon buƙata, ya bambanta daga milligram 500 zuwa 1000 sau ɗaya a rana. An bada shawara don shan miyagun ƙwayoyi da yamma. A cikin rashin sakamako masu illa daga shan miyagun ƙwayoyi bayan kwanaki 7-15, sashi, idan ya cancanta, ana iya ƙaruwa zuwa 500-1000 milligrams sau biyu a rana. Tare da gudanar da mulkin biyu na miyagun ƙwayoyi, ya kamata a sha maganin a cikin safe da maraice.
Idan ya cancanta, a gaba. Ya danganta da matakin glucose a jikin mai haƙuri, ana iya kara yawan sashi na maganin.
Lokacin amfani da maganin kiyayewa na Metformin MV Teva, ana bada shawara don ɗaukar daga 1500 zuwa 2000 MG / rana. Don ɗaukar kashi na Metformin MV Teva kada ya tsokani mai haƙuri ya sami halayen da ba su dace ba daga ƙwayar gastrointestinal, ana ba da shawarar sashi na yau da kullun ya kasu kashi biyu zuwa 3.
Matsakaicin izini na Metformin MV Teva shine 3000 MG kowace rana. Wannan kashi na yau da kullun dole ne a kashi uku.
Aiwatar da hauhawar motsa jiki a yawan magunguna na yau da kullun yana taimakawa haɓaka haƙuri na kwayoyi.
Idan kun canza daga wani magani tare da kayan aikin hypoglycemic zuwa Metformin MV Teva, da farko ya kamata ku daina shan wani magani kuma kawai sai ku fara shan Metformin.
Ana iya amfani da magani na Metformin MV Teva a lokaci guda tare da insulin a matsayin kayan haɗin magani. Lokacin amfani da miyagun ƙwayoyi tare da shi a hade, ana bada shawara don amfani da insulins masu aiki na tsawan lokaci. Yin amfani da insulins masu aiki na dindindin a haɗe tare da Metformin yana ba ku damar cimma ingantaccen sakamako na hypoglycemic akan jikin mutum.
Kafin amfani da miyagun ƙwayoyi, ana buƙatar gwajin jini don abubuwan da ke cikin sukari, an zaɓi kashi na miyagun ƙwayoyi a kowane yanayi daban daban.
Lokacin amfani da miyagun ƙwayoyi don kula da marasa lafiya tsofaffi, kashi na maganin a kowace rana bai wuce 1000 MG kowace rana ba.
Sakamakon sakamako da kuma sakamakon yawan wuce haddi
Lokacin amfani da miyagun ƙwayoyi, wasu sakamako masu illa na iya bayyana a jikin mai haƙuri.
Ya danganta da yawan abin da ya faru, ana haifar da sakamako masu illa ga rukunoni uku: sau da yawa - yawan abin ya wuce 10% ko fiye, sau da yawa - abin da ya faru daga 1 zuwa 10%, ba sau da yawa - faruwar tasirin sakamako daga 0.1 zuwa 1%, da wuya - yawan tasirin sakamako daga 0.01 zuwa 0.1% kuma da wuya haɗarin irin wannan sakamako ya zama ƙasa da 0.01%.
Abubuwan da ke tattare da sakamako yayin ɗaukar ƙwayar na iya faruwa daga kusan kowane tsarin jiki.
Mafi sau da yawa, bayyanar ƙetare daga shan miyagun ƙwayoyi ana lura:
- daga tsarin juyayi;
- a cikin narkewar abinci;
- a cikin yanayin halayen rashin lafiyan;
- take hakkin hanyoyin rayuwa.
Daga gefen tsarin juyayi na tsakiya, ana haifar da sakamako masu illa a cikin rikicewar dandano.
Lokacin shan miyagun ƙwayoyi daga jijiyar ciki, ana iya lura da rikice-rikice da rikice-rikice masu zuwa:
- Ciwon ciki
- Yana son yin amai.
- Jin zafi a ciki.
- Rashin ci.
- Rashin hankali a cikin hanta.
Allergic halayen ci gaba mafi sau da yawa a cikin hanyar erythema, itching fata da fatar a kan saman fata.
Yakamata likita ya bayyana wa masu ciwon sukari yadda ake shan Metformin domin gujewa cutarwa. Da wuya, marasa lafiya tare da tsawaita amfani da miyagun ƙwayoyi na iya haɓaka hypovitaminosis B12.
Tare da yin amfani da Metformin a kashi na 850 MG, ba a lura da ci gaban alamun cututtukan hypoglycemic a cikin marasa lafiya ba, amma a wasu lokuta lactic acidosis na iya faruwa. Tare da haɓaka wannan alamar mara kyau, mutum yana da alamun cututtuka kamar:
- jin tashin zuciya;
- da bege na amai;
- zawo
- sauke cikin zafin jiki;
- jin zafi a ciki;
- ciwon tsoka;
- saurin numfashi;
- tsananin farin ciki da gajiya mai rauni.
Don kawar da yawan abin sama da ya kamata, ya kamata ka daina shan magungunan kuma ka gudanar da aikin tiyata.
Analogues na miyagun ƙwayoyi, farashi da sake dubawa game da shi
Allunan a cikin kantin magani ana sayar da su a cikin kwali na kwali, kowannensu yana dauke da blister da yawa wanda a ciki aka tattara allunan magungunan. Kowane blister fakiti Allunan 10. Kwali na kwali, gwargwadon kwantena, na iya ƙunsar ƙarfe uku zuwa shida.
Adana kwayoyi a zazzabi da basa wuce digiri 25 a cikin duhu. Rayuwar shiryayye na miyagun ƙwayoyi shine shekaru 3.
Ba shi yiwuwa a sayi wannan magani da kanshi a cikin magunguna, tunda sakin magani ana yin shi ne kawai ta hanyar takardar sayan magani.
Nazarin marasa lafiya da suka yi amfani da wannan magani don magani sun nuna babban tasirinsa. Yawancin marasa lafiya suna barin sake dubawa game da magani. Bayyanar sake dubawa marasa kyau suna da alaƙa da bayyanar tasirin sakamako waɗanda ke faruwa lokacin da keta ƙaddamar da ka'idojin shiga tare da yawan shan magunguna.
Akwai adadi mai yawa na analogues na wannan maganin. Mafi na kowa su ne:
- Bagomet.
- Glycon.
- Glyminfor.
- Gliformin.
- Glucophage.
- Langerine.
- Metospanin.
- Metfogamma 1000.
- Metfogamma 500.
Taccena Metformin 850 ml ya dogara da kantin magani da yankin sayarwa a cikin Tarayyar Rasha. Matsakaicin farashin maganin a cikin mafi ƙarancin fakiti yana daga 113 zuwa 256 rubles.
Bidiyo a cikin wannan labarin yayi magana game da aikin Metformin.