Gensulin shine mafita don allurar ciwon sukari. Magungunan yana contraindicated idan akwai wani babban abin lura da abubuwan da aka gyara, kazalika da cutar hypoglycemia.
Gensulin H shine insulin na ɗan adam-ɗan lokaci. An samo maganin ne ta amfani da hanyoyin zamani na aikin injiniya. Ana amfani da Gensulin H don sarrafa metabolism.
Yana nufin Gensulin N fari ne, a hutawa yana amfanuwa da farin hazo, a sama akwai ruwa babu launi.
Pharmacology da abun da ke ciki
Gensulin H shine insulin na mutum wanda aka kirkireshi ta amfani da fasaha ta zamani ta zamani. Wannan maganin yana aiki azaman shirin insulin yana da matsakaicin lokacin aiki.
Magungunan yana hulɗa tare da masu karɓar ƙwayoyin sel na cytoplasmic na sel. Ana samar da hadadden da ke karfafa jiki, da yadda ake amfani da wasu manyan enzymes, sune:
- pyruvate kinase,
- hexokinase
- glycogen synthetase.
Ayyukan insulin shiri zaiyi tsawo tare da kyakkyawan amfani dashi. Wannan hanzarin ya dogara da yanayi kamar su:
- sashi
- yanki da kuma hanyar gudanarwa.
Ayyukan samfurin yana canzawa. Haka kuma, wannan ya shafi mutane daban-daban, da kuma jihohin mutane iri ɗaya.
A miyagun ƙwayoyi yana da takamaiman bayanin martaba na aiki. Don haka, kayan aiki fara aiki bayan sa'a daya da rabi, ana samun tasirinsa mafi girma a cikin tsawon awanni 3-10. Tsawon lokacin da miyagun ƙwayoyi shine 24 hours.
Abun da ke cikin miyagun ƙwayoyi ya ƙunshi IU 100 na insulinbin mutum na ɗan adam a cikin 1 ml. Wadanda suka ware sune:
- metacresol
- glycerol
- furotin sulfate,
- sinadarin zinc
- phenol
- sodium hydrogen phosphate dodecahydrate,
- ruwa don yin allura
- hydrochloric acid zuwa pH na 7.0-7.6.
Ka'idojin aiki
Gensulin H yana hulɗa tare da masu karɓar ƙwayoyin sel. Don haka, hadaddun mai karɓar insulin ya bayyana.
Lokacin da samar da AMP a cikin ƙwayoyin hanta yana ƙaruwa ko lokacin da ƙwayoyin tsoka suka shiga cikin sel, ƙwaƙwalwar mai karɓar insulin ta fara haɓaka ayyukan cikin ciki.
Ragewa a cikin glucose matakin ne ya sa ta:
- Karin aiki a cikin sel,
- ƙara yawan sukari da kyallen takarda,
- sunadaran gina jiki
- kunnawa da lipogenesis,
- glycogenesis
- raguwa a cikin yawan samar da sukari ta hanta.
Umarnin don amfani da miyagun ƙwayoyi
Sashi na maganin yana ƙaddara da likita a cikin kowane yanayi. Dangane da alamu na maida hankali ne cikin sukari na jini, yin la'akari da halaye na mutum.
Inje cikin cinya ya fi kyau, kuma za a iya yin allurar cikin buttocks, bangon ciki da na wucin gadi. Zazzabi na dakatarwa ya kamata da zazzabi dakin.
Yankin allurar shine farkon lalata shi da giya. Tare da yatsunsu biyu, ninka fata. Bayan haka, kuna buƙatar saka allura a kusurwar bene na kimanin digiri 45 a cikin tushe kuma yana yin allurar insulin ƙasa.
Ba kwa buƙatar cire allura na kusan 6 seconds bayan allura don tabbatar da cewa an sarrafa maganin sosai. Idan akwai jini a cikin allura, bayan cire allurar, sanya tabo da sauƙi tare da yatsanka. Duk lokacin da aka canza wurin allurar.
Ana amfani da Gensulin N a matsayin magani na monotherapy kuma a cikin hadaddun farke tare da insulins-gajere-Gensulin R.
A cikin akwatunan katako akwai karamin ball na gilashi, wanda ke taimakawa haɗu da mafita. Ba kwa buƙatar girgiza katun ko kwalba da ƙarfi, saboda wannan na iya haifar da ɓoye kumfa, wanda hakan ya rikitar da tarin kuɗaɗen.
Wajibi ne a kula da bayyanar da samfurin a cikin katako da vials.
Haramun ne a yi amfani da maganin idan ya ƙunshi flakes ko farin barbashi da aka manne da bangon ko kasan ganga.
Manuniya da contraindications
Ba za a iya amfani da insulin Gensulin ba idan akwai ƙwaƙwalwar haɓaka, da kuma hypoglycemia.
Ana amfani da maganin yadda ya kamata don maganin cututtukan cututtukan jini na 1 da 2.
Bugu da kari, akwai alamun masu zuwa:
- mataki na jurewa cututtukan hypoglycemic,
- m jure wa hypoglycemic kwayoyi,
- Bayani,
- aiki
- ciwon suga saboda yawan ciki.
Ana iya sanin tasirin wadannan sakamako:
- halayen rashin lafiyan halayen jiki: gazawar numfashi, zazzabi, amarticaria,
- hypoglycemia: rawar jiki, palpitations, ciwon kai, tsoro, rashin barci, ciki, tashin hankali, rashin motsi, wahayi hangen nesa da magana, hypoglycemic coma,
- acidosis da ciwon sukari da ke hawan jini,
- rauni na gani na ɗan lokaci,
- itching, hyperemia da lipodystrophy,
- hatsarin coma
- immunological halayen da mutum insulin;
- karuwa a titant antibody tare da karuwa a cikin glycemia.
A farkon farawar, ana iya samun kurakurai masu raɗaɗi da kuma edema, waɗanda ke da ɗan lokaci a yanayi.
Maganin allura lokacin amfani da insulin a cikin vials
Don shigar da insulin, ana amfani da sirinji na musamman dangane da adadin abubuwan da aka allura. Zai fi kyau a yi amfani da sirinji na masana'anta da nau'in. Wajibi ne a duba canjin sirinji, la'akari da maida hankali na insulin.
Shiri don allurar kamar haka:
- Cire kwalban kariya daga algum,
- Ku bi da abin toshe kwalabar da giya, kada ku cire abin toshe roba,
- saka iska a cikin sirinji wanda ya dace da yawan insulin,
- saka allura a cikin matatar roba ka sami iska,
- jefa kwalban tare da allura a ciki (ƙarshen allura yana cikin dakatarwa),
- theauki adadin abubuwan da suka dace a cikin sirinji,
- cire kumburin iska daga sirinji,
- waƙa da daidaiton tarin insulin kuma cire allura daga murfin.
Ya kamata a gudanar da kashi a cikin takamaiman hanya. Don yin wannan, kuna buƙatar:
- kula da fata tare da barasa a wurin allura,
- ku tattara wani fata a hannunku,
- saka allurar sirinji tare da ɗaya hannun a kusurwar 90 digiri. Kuna buƙatar tabbatar cewa an saka allurar kuma yana cikin zurfin fatar fata,
- don gudanar da insulin, tura piston har ƙasa, gabatar da sashi a ƙasa da sakan biyar,
- Cire allurar daga fata ta rike wani nau'in barasa mai kusa. Latsa swab zuwa wurin allura na 'yan dakikoki. Kar a shafa wurin allurar,
- Don hana lalata lalacewar nama, kuna buƙatar amfani da wurare daban-daban don allura. Sabuwar wuri yakamata ya zama akalla centan santimita daga wurin da ya gabata.
Kayan Fitar da Kayan Karas
Ana buƙatar katako tare da insulin Gensulin N don amfani dashi tare da almakunan sirinji, alal misali, Gensupen ko Bioton Pen. Mutumin da yake da ciwon sukari yakamata yayi nazarin umarnin don amfani da irin wannan alƙalami kuma a bi shawarwarin umarnin.
Na'urar katako ba ta bada izinin hadawa tare da sauran abubuwan ɓoye a cikin kicin ɗin ba. Ba komai a cika kwandon fanko.
Dole ne ku shigar da adadin insulin da ake so, wanda likitanku kuma ya wajabta muku. Ya kamata a canza wurin allurar don kada a yi amfani da wurin wuri fiye da 1 lokaci na wata daya.
Kuna iya haɗa maganin allurar Gensulin P tare da dakatarwar cikin ƙananan ƙwayar na Gensulin N. Wannan likita zai iya yin wannan shawarar kawai. Lokacin shirya cakuda, insulin tare da gajeren lokacin aiki, wato, Gensulin P, ya kamata a zaɓi farkon cikin sirinji.
Gabatarwar cakuda yana faruwa kamar yadda aka bayyana a sama.
M sakamako masu illa
Alamar yawan zubar jini shine haɓakar ƙwanƙwasa jini. Za'a iya ɗaukar samfuran sukari ko carbohydrate ta baki don lura da mataki mai laushi. Ga mutanen da ke da ciwon sukari, yana da matukar muhimmanci ku ɗauki Sweets, sukari, abin sha mai dadi, ko kukis tare da ku a kan ci gaba mai gudana.
Ana iya gano tasirin metabolism, wanda aka bayyana a cikin wani rashin jin daɗi ga mutum. A wasu halaye, yana iya zama:
- rikicewar hypoglycemic: ciwon kai, blanching na fata, karuwar gumi, bugun jini, rawar jiki, tashin hankali, tashin hankali, matsananciyar yunwar, paresthesia a cikin roba,
- saboda hauhawar jini, na iya samun sihiri,
- alamun rashin ƙarfi: a wasu halayen, edewar Quincke da fatar fata, har da girgiza ƙwayar cuta,
- halayen da ke cikin yanayin gudanarwa: hyperemia, itching, kumburi, tare da tsawan amfani - lipodystrophy a cikin ciwon sukari na mellitus a cikin allurar.
Tare da raguwa mai yawa a cikin taro na glucose, kamar yadda idan mutum ya rasa hankali, ya zama dole don gudanar da maganin 40% na glucose a cikin ciki. Lokacin da aka dawo da hankali, ya kamata ku ci abincin da ke da wadatar carbohydrates.
Dole ne a yi wannan don a hana maimaita tsarin cututtukan jini.
Umarni na musamman
Za'a iya rage yawan sukarin jini yayin da aka canza mutum daga insulin dabba zuwa insulin mutum. Dole ne a canza wannan canzawar koyaushe kuma za'ayi shi kawai a karkashin kulawa ta likita.
Halin samar da hauhawar jini zai iya rage ƙarfin mutum don tuki motocin, wasu hanyoyin aikin. Ana shawarci masu ciwon sukari koda yaushe su kwashe kusan 20 na sukari.
Ana daidaita sashi na insulin lokacin da:
- cututtuka
- hargitsi na thyroid gland shine yake,
- Cutar Addison
- kyakyawan magana,
- CRF,
- ciwon sukari a cikin mutane sama da 65.
Hypoglycemia na iya farawa saboda:
- yawan insulin da ya wuce
- maye gurbin magani
- damuwa ta jiki
- amai da gudawa
- cututtukan da ke rage buƙatar insulin,
- cututtuka na hanta da kodan,
- hulɗa tare da wasu kwayoyi
- canjin yankin allura.
Yayin haihuwar yara da wani lokaci bayan haihuwa, za a iya rage buƙatar insulin. Yayin shayarwa, kuna buƙatar lura da ku kullun tsawon watanni.
Sakamakon cututtukan jini na ƙwayar cuta yana ƙaruwa ta hanyar sulfonamides, shima:
- MAO masu hanawa
- carbonic anhydrase inhibitors,
- ACE hanawar, NSAIDs,
- magungunan anabolic steroid
- bromocriptine
- karafarini
- Clofibrate
- ketoconazole,
- mebendazole,
- akarijin
- cyclophosphamide, fenfluramine, shirye-shiryen Li +, pyridoxine, quinidine.
Analogs da farashin
Kudin maganin yana dogara ne akan sashi da mai ƙira. A yanar gizo, suna sayar da magani kan farashi mai ƙarancin kuɗin a cikin kantin magani.
Farashin Gensulin N ya bambanta daga 300 zuwa 850 rubles.
Analogues na miyagun ƙwayoyi sune:
- Biosulin N,
- Bari mu je kada N,
- Gaggawar insulin gaggawa
- Insuman Bazal GT,
- Insaran NPH,
- Rosinsulin C,
- Insulin Dansuwa NM,
- Protafan NM Maina,
- Rinsulin NPH,
- Humodar B 100 Rec.
Maganin yana da mafi yawan lokuta sake dubawa daga mutanen da ke da nau'in 1 da nau'in ciwon sukari na 2.
Umarnin don amfani da insulin an jera su a bidiyo a wannan labarin.