Zokor magani ne wanda ke rage matakin cutarwa na cholesterol mai cutarwa, yana kare jiki daga haɓakar cututtukan haɗari na zuciya da jijiyoyin jini. Magungunan yana da tasiri mai amfani bayan makonni 2-4 daga farkon hanya na far.
Allunan an tsara su ga marasa lafiya masu fama da cutar sankara (mellitus diabetes); a cikin wannan rukuni na marasa lafiya, yiwuwar rikicewar cututtukan jijiyoyin jini ya fado nan da nan cikin kashi 55%, mace-mace da kashi 30%, yawan aiki da bugun zuciya da kashi 37%.
Ba kowane mai haƙuri ba zai iya biyan farashin statin; matsakaicin farashin kayan haɗi a cikin kashi 10 mg shine kusan 500-700 rubles na Rasha. Don Zokor a cikin sashi na 20 MG dole ne ya biya kusan 700-900 rubles.
Idan, a kowane dalili, allunan Zokor basu dace da mai haƙuri da ciwon sukari ba, likita ya ba da shawarar cewa a yi masa magani tare da analogues na miyagun ƙwayoyi. Shahararrun shahararrun mashahuran analogues ya kamata a kira su kudade: Aterostat, Vasilip, Levomir, Zovatin. Sauran ingantattun maganganun analogues:
- Atromidine;
- Lovastatin;
- Liprimar;
- Rosuvastatin.
Duk waɗannan magungunan suna ɗauke da adadin adadin babban abu, babban tsarin aikin su ɗaya ne. A wannan yanayin, bambanci tsakanin allunan ya ta'allaka ne ga mai ƙira, farashin kayan kwalliyar da aka yi amfani da shi, alaƙar ciniki, darajar martaba.
Umarnin don amfani da miyagun ƙwayoyi
Yin amfani da miyagun ƙwayoyi Zokor dole ne ya kasance tare da daidaitaccen tsarin abinci na cholesterol. Allunan an wajabta su a cikin allurai na 5 zuwa 80 MG, ana ɗaukar su a lokacin kwanciya. Haramun ne ya zarce shawarar da aka bayar, an zabi mafi kyawun magunguna daban daban.
Ana yin gyara ba fiye da sau ɗaya a kowace kwanaki 30 ba. Ainihin magani yana daɗewa, idan an soke maganin ba da hujja ba, yanayin haƙuri zai koma asalin yadda yake.
Daidaitaccen sashi don ciwon sukari, cututtukan zuciya, bugun jini shine 40 MG kowace rana, da nauyin zuciya da abinci. Tare da wani nau'i mai laushi na hypercholesterolemia, gudanarwa yana farawa daga 10-20 MG na abu a kowane maraice, idan ya cancanta, rage ƙananan ƙwayoyin cholesterol da yawa fiye da 45%, adadin ƙwayar yana karuwa zuwa 40 MG. Ya kamata likita ya duba shi.
Matsakaicin yawan yau da kullun ya kamata ya zama bai wuce 10 MG idan an tsara Zokor tare da magunguna:
- Cyclosporin;
- Danazole;
- Gemfibrozil.
Familial hypercholesterolemia (mummunar cuta ta ƙwayar cuta) ta ƙunshi shan 40 MG kowane dare kafin lokacin barci. Wani lokaci ana nuna yin amfani da 80 MG na miyagun ƙwayoyi, yana rarraba kashi sau uku, yana riƙe tsaka-tsakin lokaci ɗaya.
Lokacin amfani dashi lokaci guda tare da Verapamil da Amiodarone, wannan darajar shine 20 MG. Wani mummunan nau'in lalacewa na koda yana buƙatar iyakance sashi na yau da kullun zuwa 10 MG.
An sanya miyagun ƙwayoyi a cikin nau'ikan allunan m, kowane kunshin ya ƙunshi guda 14-28. A cikin kantin magani zaka iya siyan Zokor 10 ko Zokor 20 MG. Baya ga babban sinadaran aikin simvastatin, allunan suna dauke da sinadarin ascorbic acid (Vitamin C), lactose monohydrate, sitaci, citric acid da talc.
Kafin magani, yana da mahimmanci a ɗauki gwaje-gwaje don aikin hanta, to, kuna buƙatar maimaita karatun daga lokaci zuwa lokaci.
Idan mafi girman ƙimar ƙa'idodin ta wuce sau uku ko fiye, ana nuna maganin yana sokewa, an maye gurbinsa da daidai analog.
Dukiya mai amfani
Ana bada shawarar magani ga masu ciwon sukari tare da kamuwa da cutar cututtukan zuciya, tare da karuwar cutar cholesterol mai cutarwa. Yana magance cututtukan cututtukan zuciya, yana rage yiwuwar mutuwa a cikin cututtukan zuciya, kuma ya zama ma'aunin rigakafin rikitarwa na zuciya, irin su bugun zuciya, bugun zuciya.
Masu ciwon sukari na iya dogaro kan hana haɓakar lalacewa ga tasoshin yanki. Tare da cutar ischemic tare da hypercholesterolemia, ci gaba da jijiyoyin zuciya atherosclerosis an jinkirta.
Matsakaicin mafi girman abubuwan aiki yana gudana bayan sa'o'i 1.3-2.4 bayan shan allunan Zokor. Kimanin kashi 85% na wani abu na baki yana shan nan da nan. Idan aka kwatanta da sauran magunguna, ana lura da matakan simvastatin a cikin ƙwayoyin hanta.
Aiwatar da Zokor ya kamata:
- idan ya cancanta, sake yin tiyata na jijiyoyin jini;
- don raunana hare-hare na angina pectoris;
- zuwa ƙananan duka da ƙananan ƙwayoyin cholesterol;
- haɓaka cholesterol mai amfani;
- idan ya cancanta, sarrafa adadin triglycerides.
Bayan abu na farko ya shiga hanta, ana yin metabolized, sannan ana fitar da metabolites da maganin tare da bile. Yin amfani da miyagun ƙwayoyi ba ya dogara da cin abinci ba, abinci ba ya shafar magungunan magunguna ba.
Tare da amfani da tsawan lokaci, tarawa a cikin kasusuwa na jiki baya faruwa.
M Yan adawar da Contraindications
A matsayinka na mai mulkin, jiki ya yarda da Zokor sosai, an raba shi ta wata hanya ta zahiri. Duk da wannan, kamar sauran magunguna, akwai m halayen. Kimanin 0.1-10% na masu ciwon sukari suna kamuwa da cutar ƙanjamau, tashin hankalin asthenic, asarar gashi, farin ciki, jaundice, da polyneuropathy na ciwon sukari.
Bugu da ƙari, dermatomyositis, myalgia, kumburi a cikin farji, ƙuƙwalwar ƙwayar tsoka, dyspepsia ba a cire su ba. Matsalar fata, itching, na gefe nephropathy, paresthesia, rhabdomyolysis.
Yin amfani da Allunan zai iya haifar da cututtukan tsarin rigakafi, halayen rashin lafiyan: kumburi, cututtukan lupus, urticaria, ƙarancin jijiya ga haske, arthralgia. Ana gano marasa lafiya da cuta na rayuwa tare da karuwa a cikin ESR, hauhawar fata da karancin numfashi.
Akwai bayanan matsayin:
- haɓaka ayyukan halitta na phosphokinase;
- karuwa a cikin adadin transaminase;
- haɓakar taro na alkaline.
Idan alamun da aka yi la'akari da su sun faru, ana buƙatar don rage sashi ko dakatar da shan shi, yana maye gurbin maganin tare da analogues.
Yana da Zokor da contraindications, sun haɗa da ciki, lokacin shayarwa, rashin haƙuri a cikin abubuwan maganin. Ba za ku iya shan Allunan don cututtukan hanta masu aiki ba, gami da transaminase mai haɓaka na kowane etiology. Ga masu ciwon sukari tare da jigon ƙwayar transaminase mai ɗorewa, an tsara magunguna da taka tsantsan.
Wani irin wannan shawarar don shan barasa, rhabdomyolysis. Allunan ba a ba da umarnin allurar ba a cikin yara.
Yin hulɗa tare da wasu kwayoyi
Yana da mahimmanci don daidaita shan Zokor tare da wasu magunguna, wannan zai guje wa raguwa game da tasirin warkewa.
Fibrates, ban da fenofibrate, nicotinic acid tare da Zokor yana ninka sakamako na hypocholesterolemic, yana ƙaruwa da yiwuwar haɓaka ciwon sanƙara.
Kwayoyin kwayoyi na iya shafar tasirin magungunan coumarin; yayin da aka yi amfani da su gaba daya, an nuna wajibcin lura da likita. Tare da wannan dabarar, ana iya hana zubar jini.
Amfani na yau da kullun tare da wasu kwayoyi yana ƙara haɗarin myopathy, yawanci muna magana ne game da kwayoyi Erythromycin, Terithromycin, Ketoconazole. An ba da shawarar ya dauki allurai na magungunan ƙwayoyi:
- Verapamil;
- Amiodarone;
- Danazole;
- Sankarini.
Wata shawarar kuma ita ce a guji shan lemun zaki mai yawa, musamman innabi. Samfurin yana ƙara ayyukan miyagun ƙwayoyi a cikin jini na jini.
Ana sayar da allunan Zokor na musamman ta hanyar takardar izini daga likitanka.
Rayuwar shiryayye na miyagun ƙwayoyi, batun yanayin zafin jiki, bai wuce shekara biyu ba daga ranar da aka ƙera shi.
Umarni na musamman
Amfani da Zokor na dogon lokaci na iya haifar da myopathy tare da alamun halayyar: ciwon tsoka, rauni gaba ɗaya, tare da haɓaka a cikin dubun lokutan creatine phosphokinase.
Myopathy yana sanya kansa jin gazawar sigar na biyu, yana iya haifar da mummunan sakamako. Yiwar yiwuwar kamuwa da ciwon sanƙuwar mahaifa yana ƙaruwa da haɓakar da wani abu a cikin jini na jini yayin shan magungunan inhibitory.
Duk wani mai ciwon sukari wanda aka wajabta wa Zokor ya kamata ya san da buƙatar tuntuɓar likita da wuri-wuri ga kowane tsoka kuma musamman jin ciwo mara bayyana.
A farkon farkon aikin jiyya, tare da kowane karuwa akan sashi, ana buƙata don saka idanu kan yawan ƙwayar halittar phosphokinase. Idan akwai alamun yin maganin tiyata, ki daina shan kwayoyi kwana biyu kafin aikin. Don haka suna yin shi a cikin kwanakin farko bayan tsoma bakin.
Kafin yin magani tare da miyagun ƙwayoyi kuma a lokacin jiyya, yana da mahimmanci don saka idanu kan aikin hanta, ana nuna ƙarin nazarin ga waɗanda masu cutar sukari waɗanda ke karɓar ƙwayoyi mai yawa na abu.
Analog na Zokora Rosuvastatin
Ga masu fama da cutar siga tare da matsalolin cholesterol masu yawa, an maye gurbin Zokor tare da allunan rosuvastatin. Magungunan yana yin kyakkyawan aiki na al'ada don samarda ƙwayoyin cuta mai yawa kuma yana rage abu mai yawa.
An danganta magungunan ga mutum-mutumi na hudu, ana amfani da shi sosai don kawar da hypercholesterolemia, kuma ana amfani dashi azaman maganin prophylactic akan cututtukan jijiyoyin bugun zuciya da sakamakonsa.
Godiya ga tsarkake tasoshin jini, da samuwar allurai atherosclerotic, hana ci gaban bugun zuciya, da bugun zuciya tare da tsinkayar cututtukan zuciya.
Allunan rosuvastatin sune aka fi yin nazari a tsakanin statins, an tabbatar da ingancin gwaji. Shahararren fasalin daga analogues shine ayyukan:
- yi yaƙi da cholesterol mara kyau;
- taimako na raunin tafiyar matakai;
- ƙara kyau cholesterol.
Babban mahimmanci shine hanawar kumburi mai narkewa a jikin mai ciwon sukari, saboda wannan shine ainihin wannan shine ke haifar da atherosclerosis.
Magungunan yana motsa jiki don samar da nitrogen, yana ba da gudummawa ga shakatawa na jijiyoyin jini, ƙirƙirar ƙarin sakamako. Bayan amfani da allunan, abubuwa masu aiki nan da nan suka shiga cikin tsarin jini, ana rarraba su ko'ina cikin kyallen da sel. Haka kuma, kimantawa yayi kasa da na analogues, tsawon lokacin hutun yana da girma.
Za'a iya kaiwa ga yawan filayen plasma 5 hours bayan fitowar. Duk da gaskiyar cewa an tsara magungunan a cikin ragewar sashi, wannan bai tsoma baki tare da hulɗar al'ada tare da sauran magunguna.
Iyakokin da contraindications
Kamar sauran Allunan, rosuvastatin yana da contraindications. Da farko dai, muna magana ne game da rashin haƙuri ga kowane sinadaran ƙwayoyi (gami da magabata). Dole ne a tuna cewa ba a ba da magunguna ga masu ciwon sukari a lokacin daukar ciki, ga yara 'yan ƙasa da shekaru 18, ban da halayen hypercholesterolemia.
An haramtawa kwayoyin hana daukar ciki a cikin gazawar hanta sakamakon lalacewa ta hanyar aiki yayin lalacewar sel, matakan girman hanta na hanta.
Kada ayi izinin amfani da wannan lokaci tare da cyclosporine. Hakanan wani contraindication ne myopathy - pathology daga cikin kwarangwal kwarangwal tsokoki, wani tsinkaye zuwa ga ci gaban.
Ana ba da bayani game da gumaka a cikin bidiyon a cikin wannan labarin.
