Rosucard yana nufin gumaka waɗanda ke rage tasirin cholesterol a cikin jini. Sunan kasa da kasa mai zaman kansa na sunan shine Rosuvastatin (Rosuvastatin).
Ana amfani da miyagun ƙwayoyi a cikin lura da hypercholesterolemia, rigakafin samuwar atherosclerotic plaques da cututtukan zuciya. Likita ya kayyade sashi na miyagun ƙwayoyi dangane da tsananin cutar da yanayin halayen mutum na haƙuri.
Labarin ya ƙunshi bayanin asali game da Rosucard (10.20.40 mg), farashinsa, sake dubawa na haƙuri da kuma alamun analogues.
A tsari da abun da ke ciki na miyagun ƙwayoyi
An dauki Rosucard magani ne wanda ke da tasirin rage kiba. Abubuwan da ke aiki suna hana samar da HMG-CoA reductase. Godiya ga wannan enzyme, HMG-CoA an canza shi zuwa mevalonic acid, wanda shine farkon abubuwan cholesterol.
Kamfanin kamfanin kera magunguna na kasar Czech Zentiva ne ya fitar da maganin. Ana yin Rosucard a cikin kwamfutar hannu wanda aka rufe don amfani da baka. Kwamfutar hannu tana da launin ruwan hoda mai haske, yanki mai faɗi a ɓangarorin biyu da siffar elongated.
Abubuwan da ke aiki da maganin shine rosuvastatin. 1 kwamfutar hannu na Rosucard na iya ƙunsar 10, 20 ko 40 mg na abu mai aiki. Bayan wannan, magungunan sun hada da kayan taimako, wadanda suka hada da:
- sodium crosscarmellose;
- microcrystalline cellulose;
- lactose monohydrate;
- magnesium stearate.
Fim din ya ƙunshi abubuwa kamar talc, macrogol 6000, jan oxide, hypromellose da titanium dioxide.
Blaya daga cikin kumburi ya ƙunshi Allunan 10. Ana yin marufi ɗaya, ɗaya na uku ko tara. Rosucard marufi yana tare da kullun tare da littafin bayani don amfanin allunan.
Hanyar aiwatar da babban abu
Ayyukan rosuvastatin an yi niyya ne don haɓaka matakin masu karɓa na LDL a cikin sel na hanta parenchyma (hepatocytes). Increasearuwar adadin su yana ƙaruwa da haɓakawa da rarraba LDL, raguwa a cikin samar da VLDL da jimlar abubuwan "mummunan" cholesterol.
Sakamakon rage ƙwayar lipid na Rosucard ya dogara kai tsaye akan sigar da aka ɗauka. Bayan mako 1 na shan miyagun ƙwayoyi, ana lura da raguwar matakin cholesterol, bayan makonni 2 90% na mafi girman tasirin warkewa an samu. A mako na 4, ana lura da yanayin karfafawar kwayar cholesterol a matakin da aka yarda da shi.
Magungunan suna taimakawa haɓaka matakan HDL, waɗanda ba su da atherogenic kuma ba a sanya su cikin nau'ikan filaye da haɓaka akan bangon jijiya ba.
Rashin abinci na yau da kullun na rosuvastatin baya canza sigogi na pharmacokinetic. Abun yana ma'amala da sunadarai na jini (aƙalla yana ɗaure wa albumin), sha yana faruwa ta hanta. Wani sashe na iya ƙetara mahaifa.
Kusan 90% na rosuvastatin an cire su daga jiki ta cikin hanji, sauran ta hanjin kodan. Magungunan magunguna na kayan aiki ba su dogara da jinsi da shekaru ba.
Manuniya da contraindications don amfani
Likita ya ba da tabbacin Rosucard idan cutar ta gano yana da alaƙa da ƙara yawan ƙwayoyin cuta.
Amfani da kai kansa haramunne.
Akwai maganganu masu yawa waɗanda gazawa cikin narkewar ƙwayar cuta ta lipid.
Amfani da Allunan yana dacewa da:
- Primary ko hade hypercholesterolemia.
- A hadadden lura da hypertriglyceridemia.
- Namiji (gado) homozygous hypercholesterolemia.
- Saurin ci gaban atherosclerosis (ƙari ga abinci).
- Yin rigakafin cututtukan zuciya da jijiyoyin jini dangane da asalin cutar atherosclerosis (ciwon zuciya, hauhawar jini, bugun jini da bugun zuciya).
Yin amfani da magani tare da kashi 10 da 20 MG ne contraindicated a cikin:
- kasancewar hankalin kowane mutum ga abubuwan da aka gyara;
- dauke da yaro ko shayarwa;
- bai kai shekara 18 ba;
- haɓakar ciwon sanƙara (cutar yoyon fitsari);
- hadaddun jiyya tare da cyclosporine;
- activityarin aikin enzyme na CPK ta fiye da sau biyar;
- kin mace ta hana isasshen rigakafi;
- gazawar hanta da kasala mai rauni;
- hadaddun tsarin kula da masu kare cutar kanjamau.
Hakanan akwai jerin halayyar contraindications don maganin 40 MG:
- Halin gado na rashin ƙwaƙwalwa na.
- Barasa shan giya da barasa.
- Rashin gajiyawar yanayin ishara.
- Myelotoxicity yayin ɗaukar HMG-CoA reductase blockers da fibrates.
- Rashin lafiyar thyroid.
- Hadakar mai amfani da fibrates.
- Kwayoyin cuta daban-daban da ke haifar da karuwa a cikin taro na rosuvastatin a cikin jini.
Hakanan ba a ba da shawarar yin amfani da sashi na 40 MG ta wakilai na tseren Mongoloid ba saboda kasancewar halayen mutum.
Umarnin don amfani da miyagun ƙwayoyi
Allunan basu bukatar a ciji ko aana, an hadasu da ruwa. Shan maganin ba ya dogara da lokacin rana ko cin abinci.
Kafin rubuta Rosucard, likita ya ba da shawarar sosai cewa mara lafiya ya bi abin da ake buƙata don rage yawan ƙwayar cholesterol.
Satin farko na maganin shine kwayar 0.5-1 (5-10 mg). Bayan makonni huɗu, likita zai iya ƙaruwa da kashi. Wata karuwa a cikin maganin yau da kullun zuwa 40 MG na yiwuwa ne kawai idan akwai yawan cholesterol sosai da kuma yiwuwar rikice-rikice na cututtukan zuciya, lokacin da kashi 20 na rana na yau da kullun ba shi da tasiri.
Teburin da ke ƙasa yana nuna alamun amfani da Rosucard a cikin mutane na tseren Mongoloid, tare da cututtukan cututtukan tsarin biliary da cuta na jijiyoyin jini.
Cuta / yanayin | Siffofin shan kwayoyin |
Rashin hanta | Idan ya wuce maki 7, ya zama dole don daidaita sashi na maganin. |
Rashin wahala | Sashi shine 5-10 MG kowace rana. Tare da matsakaicin matsakaici, 40 MG kowace rana bai kamata a cinye shi ba, tare da ƙarancin wahala, rosuvastatin an haramta shi sosai. |
M ga myopathy | An yarda da marasa lafiya su ɗauki 10-20 MG na miyagun ƙwayoyi. A kashi na 40 MG ne contraindicated a cikin wannan predisposition. |
Tsere na Mongoloid | Tsarin yau da kullun na miyagun ƙwayoyi shine 5-10 mg. An hana kara yawa sosai. |
Rayuwar shelf shine watanni 24, bayan wannan lokacin, shan magungunan an haramta shi sosai. An adana kwantena daga ƙananan yara a zazzabi na 25 ° C.
Rashin Amincewa da Yawan .auka
Sakamakon sakamako na iya faruwa yayin ɗaukar magani.
Idan mummunan halayen ya faru, mai haƙuri ya kamata ya daina amfani da Rosucard kuma nemi shawarar ƙwararren likita.
Abubuwan da ke haifar da sakamako kai tsaye suna dogara ne akan sashi na miyagun ƙwayoyi, sabili da haka, ana yawan lura dashi saboda gudanar da allunan tare da sashin 40 MG.
Koyarwar tana kunshe da wadannan bayanan game da abubuwan rashin kyau:
- Rashin cututtukan cututtukan cututtukan ciki - hare-hare na tashin zuciya da amai, jin zafi a cikin yankin na epigastric, wani lokacin ci gaban pancreatitis da hepatitis.
- Abubuwan da suka shafi ƙwayar cuta - proteinuria (gaban sunadarai a cikin fitsari), hematuria (kasancewar jini a cikin fitsari).
- Bayyanar bayyanar cututtuka - itching, rashes a kan fata, urticaria.
- Rashin ƙwayoyin tsoka - raunin tsoka, raunin ƙwayar tsoka, lalata ƙwayoyin tsoka.
- CNS dysfunction - migraine na lokaci-lokaci, fainting, barcin mara kyau da rashin barci, damuwa.
- Take hakkin gabobin haihuwa - haɓakar gaman dabbobi masu sha a cikin maza.
- Abubuwan da suka shafi fata da ƙananan ƙwayoyin cuta sune cututtukan Stevens-Johnson (ko necrotic dermatitis).
- Rushewa a cikin tsarin endocrine - haɓakar ciwon sukari wanda ba shi da insulin-dogara da ciwon sukari mellitus II na II.
- Gazawar numfashi - bushe tari da gazawar numfashi.
Tun da Pharmakokinetics na kayan aiki mai aiki ba dogaro-da-kashi ba, yawan abin sama da ya kamata ba ya bunkasa. Wani lokaci yana yiwuwa a ƙara alamun m halayen.
Farfesa ya hada da matakan kamar cinye ciki, amfani da sihiri da kuma kawar da alamun.
Yarda da wasu kwayoyi
Yardawar Rosucard tare da wasu magunguna na iya haifar da raguwa ko akasin haka yana ƙaruwa da tasiri na abubuwan aiki, da kuma haifar da sakamako masu illa.
Don kare kansa daga halayen da ba su da kyau, mara lafiya ya kamata ya sanar da likita game da duk cututtukan da ke haɗuwa da magunguna da aka ɗauka.
Mai zuwa tebur yana ɗauke da jerin magunguna waɗanda gudanarwa na lokaci ɗaya suna ƙaruwa ko rage tasirin warkewar Rosucard.
Inganta tasirin | Rage sakamako |
Cyclosporin (mai ƙarfi immunosuppressant). Acid na Nicotinic Masu hana HIV kwayar cutar. Abubuwan hanawa. Gemfibrozil da sauran fibrates. | Erythromycin (maganin rigakafi daga aji na macrolide). Antacids, gami da aluminum da magnesium hydroxide. |
Akwai bayanai cewa tare da hadaddun amfani da Rosucard tare da Warfarin da sauran masu ƙin bitamin K, rage yawan INR mai yiwuwa ne.
A lokacin gwaje-gwajen kimiyya, babu wani gagarumin aiki da ya shafi kiba tsakanin abubuwan Rosucard da Ketoconazole, Fluconazole, Itraconazole, Digoxin, Ezetimibe.
Haramun ne shan kwayoyi da barasa a lokaci guda. Guje wa barasa da shan sigari na taimaka wa karancin cholesterol zuwa matakin da za'a yarda dashi.
Cost da haƙuri haƙuri
Tunda Rosucard magani ne da aka shigo dashi, farashi mai tsada ne sosai. Duk da tasirin maganin, farashinsa shine babban koma baya.
A matsakaici, ana iya siyan Rosucard 10 MG (allunan 30) akan farashin 595 rubles, 20 MG don 875 rubles, 40 MG don 1155 rubles. Don adana kuɗin ku, zaku iya sanya tsari akan layi akan gidan yanar gizon wakilin hukuma.
Yawancin marasa lafiya suna lura da ingantaccen sakamako na warkewa daga shan miyagun ƙwayoyi. Babban ab advantagesbuwan amfãni shine nau'i mai dacewa kuma adadin amfani kawai 1 lokaci kowace rana.
Koyaya, ana sake samun bita mara kyau na marasa lafiya akan Intanet.
Masu ilimin hanyoyin kwantar da hankali da likitocin zuciya sun danganta mummunan mummunan mummunan sakamako tare da manyan magunguna. Wannan abin da likitan ya ce Yakimets:
"Na kimanta inganci na wannan jikan - yana daidaita daidaiton ƙwayar lipid a cikin hanyoyin da ba za a iya magance su ba da ƙananan rauni, ƙari ne ta dabi'a, farashin idan aka kwatanta da Krestor synonym. Akwai sakamako masu illa, amma sun kasance ba kasafai ba, saboda na tsara 5-10 MG don gano ƙananan cuta."
Daidaitawa da kwatankwacin maganin
A cikin yanayin inda aka hana mai haƙuri yin Rosucard saboda contraindications ko sakamako masu illa, likita ya zaɓi madadin mai amfani.
A kan kasuwar magunguna zaka iya samun maganganu da yawa na maganin, wanda ya ƙunshi kayan aiki guda ɗaya. Daga cikinsu akwai:
- Rosuvastatin;
- Kanta
- Rosistark;
- Tevastor
- Akorta;
- Roxer;
- Rosart
- Mertenyl;
- Rosulip.
Hakanan akwai alamun analogs waɗanda suka bambanta cikin abubuwan da ke aiki, amma an haɗa su cikin rukuni na statins:
- Zokor.
- Atoris.
- Vasilip
Zokor. Ya haɗu da sinadaran simvastatin mai aiki, wanda ke hana HMG-CoA reductase. Kamfanin masana'antar magunguna na Amurka da Netherlands ne suka yi shi. Matsakaicin farashin shiryashi (A'a. 28 10mg) shine 385 rubles.
Atoris. Wannan misali ne mai rahusa na Rosucard, saboda farashin kayan kwantena (A'a 30 10mg) shine 330 rubles. Abubuwan da ke aiki shine atorvastatin, wanda ke ƙara yawan ayyukan masu karɓar LDL waɗanda ke cikin hanta da ƙwayoyin extrahepatic.
Vasilip. Magungunan sun ƙunshi simvastatin a cikin sashi na 10.20 da 40 milligrams. Yana da alamomi iri ɗaya da kuma contraindications kamar Rosucard. Za'a iya siyan magungunan don 250 rubles kawai (A'a. 28 10mg).
Game da kwayoyi dangane da rosuvastatin an bayyana su a cikin bidiyo a wannan labarin.