A wasu halaye, ana ba da shawarar yin amfani da magunguna don magance tasirin cholesterol a jikin mutum.
Ofaya daga cikin magungunan rage ƙwayar lipid wanda ya karya matakan farko na kwayar cholesterol a cikin hanta shine Holetar.
Magungunan, wanda aka saki a Slovenia, an yi shi ne don maganin cututtukan cututtukan zuciya. An ba da shawarar yin amfani da shi a cikin hyperlipidemia na farko da rage jinkirin ci gaba da jijiyoyin zuciya atherosclerosis. Ana samun maganin a cikin allunan 20 ko 40 MG. Babban abu mai aiki da ƙwayar ƙwayar cuta shine lovastatin.
Lovastatin yana taimakawa rage gudu na enzymatic na ciki na samuwar cholesterol a cikin hanta kuma ya rushe matakin farko na aikinta - samar da mevalonic acid. A cikin jikin, lovastatin an canza shi zuwa tsari mai aiki, wanda ke taimakawa rage samuwar cholesterol da hanzarta fitowar ta da lalata. Magungunan yana rage abun cikin lipoproteins mai yawa a cikin jini, kuma yana kara yawan abun ciki na HDL.
Amfanin magani tare da wannan magani shine cewa amfani dashi baya haifar da tarawa mai guba a cikin jiki.
A cikin ciki, lovastatin yana shan hankali a hankali kuma baya cika - kusan kashi ɗaya bisa uku na kashi da aka ɗauka. Ya kamata a sha miyagun ƙwayoyi tare da abinci, tun lokacin da aka ɗauki allunan a kan komai a ciki, ƙwayar plasma ta kasance ta uku ta ƙasa da lokacin da aka ɗauke ta da abinci. Ana lura da mafi girman nauyinsa bayan sa'o'i 2-4, sannan yawan kumburin plasma ya ragu, yana kaiwa kimanin 10% na matsakaicin a rana.
Lovastatin ya kewaya ta cikin hanjin mutum da kodan.
Alamu sune:
- An tsara choletar don rage cholesterol LDL da triglycerides a cikin jini a cikin marasa lafiya da keɓaɓɓen hypercholesterolemia. An wajabta don ƙarancin amfanin maganin rage cin abinci da sauran wakilai waɗanda ba magunguna ba;
- Jiyya na atherosclerosis na jijiyoyin jini a cikin marasa lafiya da cututtukan zuciya da jijiyoyin jini don rage jinkirin ci gaba da cutar.
Yardajewa:
- Kasancewar rashin lafiyar jiki zuwa lovastatin ko wasu abubuwan magunguna;
- Kasancewar cututtukan hanta daban-daban a cikin aiki;
- Lokacin daukar ciki a cikin mata da shayarwa;
- Age zuwa shekaru 18.
Kamar kowane magani, Holetar yana da sakamako masu illa da yawa, a cikinsu akwai mafi yawan lokuta ana samun su:
- Jin zafi a ciki;
- Bakin ciki, tashin zuciya;
- Take hakkin jijiyoyi a cikin hanji ko maƙarƙashiya;
- Kirkewa da jin zafi a cikin tsokoki;
- Ciwon kai, danshi;
- Vioarya ta hanyar gani da dandano mai yiwuwa ne;
- Janar rauni, rikicewar bacci;
- Levelsara matakan wasu kwayoyin halittu;
- Yawancin halayen rashin lafiyar jiki.
Allunan ana daukar su a baki yayin abinci. Kafin komawa ga amfani da miyagun ƙwayoyi kuma yayin amfani da shi ana bada shawara don bin abincin musamman.
Tare da hyperlipidemia, maganin da aka ba da shawarar lovastatin daga 10 zuwa 80 MG sau ɗaya a rana. Da farko, don marasa lafiya tare da matsakaici hypercholesterolemia, Holetar an wajabta 20 MG sau ɗaya a rana yayin abincin yamma. Dangane da alamun bayyanar cututtuka na hypercholesterolemia, an ba da shawarar ninka kashi biyu na yawan yau da kullun. Idan ya cancanta, ana iya karuwa da adadin ƙwayar don cimma daidaitattun matakan cholesterol. Matsakaicin matsayinta shine 80 MG kowace rana a cikin guda ɗaya ko sama yayin cin abinci;
A cikin atherosclerosis na jijiya, yawan shawarar da aka bayar shine daga 20 zuwa 80 MG kowace rana, sau daya ko a allurai kashi biyu.
Yana da mahimmanci a tuna cewa sashi da lokacin gudanarwa ana ƙaddara ta likita mai halarta.
Doaukar magungunan ƙwayar cuta ba ya haifar da bayyanar takamaiman bayyanar cututtuka, duk da haka, lokacin ɗaukar manyan allurai na Holetar, ana bada shawara don kula da aikin hanta.
Ana iya lura da karuwa a cikin matakin lovastatin a cikin jini, wanda ke haifar da ci gaban myopathy tare da rhabdomyolysis da gazawar koda, ana iya lura yayin shan Holetar da kwayoyi kamar nicotinic acid; Cyclosporin; maganin rigakafin macrolide; magungunan antifungal; Masu hana HIV kwayar cutar.
Haɗin haɗakar Holetar da warfarin a wasu yanayi yana taimakawa ƙara haɓaka tasirin ayyukan coagulation na jini, wanda hakan na iya haifar da haɗarin hauhawar jini.
Game da kulawa ta lokaci-lokaci na wadannan kwayoyi, wajibi ne a gudanar da gwaje-gwaje akai-akai don sanin lokacin coagulation na jini.
Amfani da lovastatin mai yiwuwa ne awanni 4 bayan shan Colestyramine, tunda ragi a bioavailability da bayyanar tasirin ƙara zai yiwu.
Akwai sake dubawa daban-daban na maganin daga marasa lafiyar da suka yi amfani da shi. Ya kamata a lura cewa yawancinsu masu gaskiya ne. Tare da gudanar da ingantacciyar hanyar sarrafawa, bayyanar mummunan halayen daga jikin mutum ba'a lura dashi ba, matakan cholesterol sun ragu sosai.
Akwai da yawa analogues na wannan miyagun ƙwayoyi waɗanda suke da nasu halayen mara kyau da marasa kyau. A wannan halin, ba a yarda da amfani da magunguna ba tare da shawara da shawarwarin likita masu halartar ba.
- Atorvastatin-TEVA. Akwai magungunan a cikin allunan. An bambanta shi da wani abu mai aiki - atorvastatin, duk da haka, jerin abubuwan da ke nuna alamun gudanarwa kusan iri ɗaya ne ga choletar. Yana da yawan contraindications, ciki har da ciki, lactation, shekaru a karkashin shekaru 18;
- Lipoford. Yana daga ɗayan shahararrun shirye-shiryen da Indian yayi don amfanin ciki. Atorvastatin shima wani sinadari ne mai aiki a cikin adadin mil 10 na kowace kwamfutar hannu. Yana da jerin hanyoyin contraindications da kuma sakamako masu illa, saboda haka, kafin amfani da shi, dole ne ka nemi masanin kwararru;
- Cardiostatin. Magani ne na Rasha wanda ke da nau'in farashin ɗan kadan. Abunda yake aiki shine lovastatin a sashi na 20 ko 40 mg. Sanarwa a cikin kayan kwali na allunan 30, wanda shine Allunan 10 fiye da na ainihin.
Don haka, Holetar samfurin magani ne, amfanin da ake bi don idan ya cancanta, aiwatar da aikin jiyya. Sashi yana ƙaddara ta likita mai halartar. Tare da haɓaka sakamako masu illa, ana soke maganin, ana maye gurbin shi da analogues tare da kayan aikin warkewa iri ɗaya.
Masana za su yi magana game da mutummutumai a cikin bidiyo a cikin wannan labarin.
