Insulin Lantus Solostar: sake dubawa da farashi, umarnin don amfani

Insulin Lantus SoloStar kwatankwacin kwatancen hormone ne tare da tsawan lokaci, wanda aka yi niyya don maganin nau'in 1 da nau'in ciwon sukari na 2. Abubuwan da ke aiki da miyagun ƙwayoyi shine insulin glargine, ana samun wannan kayan ne daga Escherichiacoli DNA ta amfani da hanyar ma'adanar.

Glargin yana da ikon ɗaure wa masu karɓar insulin kamar insulin ɗan adam, don haka miyagun ƙwayoyi suna da duk abubuwan da suka dace na ilimin halittu a cikin hormone.

Da zaran cikin kitse na subcutaneous, insulin glargine yana haɓaka samuwar microprecipitate, saboda wanda adadin kwayoyin zai iya shigar da jinin jini koda yaushe. Wannan kayan yana samar da ingantaccen bayanin hangen nesa mai santsi.

Siffofin magani

Wanda ya kirkiro maganin shine kamfanin kasar Sanofi-Aventis Deutschland GmbH. Babban abu mai mahimmanci na miyagun ƙwayoyi shine insulin glargine, abun da ke ciki ya haɗa da abubuwan taimako a cikin tsarin metacresol, zinc chloride, glycerol, sodium hydroxide, hydrochloric acid, ruwa don yin allura.

Lantus shine bayyananne, ruwa mara launi ko kusan ruwa mara launi. Mayar da mafita don mafitar subcutaneous shine 100 U / ml.

Kowane katun gilashin yana da maganin mil 3 na magani; an ɗora wannan katangar a cikin murfin sirinji na SoloStar. Ana sayar da alkalan insulin biyar don sirinji a cikin kwali, kwalin ya haɗa da jagorar koyarwa don na'urar.

• Za'a iya siyan magani wanda ke da kwalliya mai inganci daga likitoci da marasa lafiya a kantin magani kawai tare da takardar sayen magani.
• An nuna insulin Lantus ga mellitus-insulin-da ke fama da ciwon suga a cikin manya da yara kanana shekaru shida.
• Tsarin musamman na SoloStar yana ba da damar jiyya a cikin yara sama da shekara biyu.
• Farashin kayan haɗi na alkalami biyar da magani na 100 IU / ml shine 3 500 rubles.

Umarnin don amfani da miyagun ƙwayoyi

Kafin yin amfani da miyagun ƙwayoyi, ya kamata ka nemi likitanka, wani endocrinologist zai taimake ka ka zaɓi madaidaicin sashi kuma ya tsara ainihin lokacin allura. Insulin yana allurar subcutaneously sau ɗaya a rana, yayin da allurar take yin ta sosai a wani lokaci.

An saka maganin a cikin kitse na cinya, cinya ko ciki. Kowane lokaci ya kamata ku canza wurin allurar don kada haushi ya haifar da fata. Za'a iya amfani da maganin a matsayin magani mai zaman kanta, ko a hade tare da wasu magunguna masu rage sukari.

Kafin amfani da insulin Lantus SoloStar a cikin sirinji na alkalami don magani, kuna buƙatar gano yadda ake amfani da wannan na'urar don yin allura. Idan a baya, an gudanar da aikin insulin tare da taimakon insulin aiki na dindindin ko na matsakaici, yawan suturar insulin yau da kullun yakamata a daidaita.

1. Game da canji daga allura sau biyu na insulin-isophan zuwa allura guda daya da Lantus ya yi a cikin makonni biyu na farko, yakamata a rage kashi na rana na yau da kullun da kashi 20-30. Ya kamata a biya kason da ya rage ta hanyar kara yawan amfani da insulin gajere.
2. Wannan zai hana ci gaban hauhawar jini a cikin dare da safe. Hakanan, lokacin sauya sheka zuwa sabon magani, ana kara samun amsa game da allura na kwayoyin lokacin. Sabili da haka, da farko, ya kamata a hankali kula da matakin sukari na jini ta amfani da glucometer kuma, idan ya cancanta, daidaita tsarin sashi na insulin.
3. Tare da ingantacciyar ƙa'idar aiki na metabolism, wani lokacin hankali ga miyagun ƙwayoyi na iya ƙaruwa, a wannan batun, ya zama dole don daidaita tsarin sashi. Hakanan ana buƙatar canji a kashi yayin canza yanayin rayuwar mai ciwon sukari, haɓaka ko rage nauyi, canza lokacin allura da sauran abubuwan da ke taimakawa ga farawar hypo-ko hyperglycemia.
4. An haramta yin amfani da miyagun ƙwayoyi don gudanarwar cikin jijiya, wannan na iya haifar da haɓakar haɓaka mai haɗari. Kafin yin allura, yakamata ka tabbata cewa alkairin danshi mai tsabta ne kuma mai bakararre.

A matsayinka na doka, ana gudanar da insulin na Lantus a maraice, sashi na farko na iya zama raka'a 8 ko fiye. Lokacin canzawa zuwa sabon magani, nan da nan gabatar da babban kashi yana da haɗari ga rayuwa, don haka yakamata a yi gyara a hankali.

Glargin fara aiki da sa'a guda bayan allura, a matsakaita, yana yin awowi 24. Koyaya, yana da mahimmanci a la'akari cewa tare da babban sashi, tsawon lokacin aikin miyagun ƙwayoyi zai iya kaiwa awanni 29.

Kada insulin Lantus tare da wasu kwayoyi.

Side effects

Tare da gabatarwar wani sashi mai yawa na insulin, mai ciwon sukari na iya fuskantar cutar sikari. Kwayar cuta ta rikicewar jiki yakan fara bayyana kwatsam kuma yana haɗuwa da jin gajiya, ƙaruwa mai rauni, rauni, raguwar hankali, matsananciyar damuwa, tashin hankali na gani, ciwon kai, tashin zuciya, tashin hankali, da yaɗuwa.

Wadannan bayyanannu yawanci alamu ne a cikin nau'ikan ji na yunwar, tashin hankali, tashin hankali ko rawar jiki, damuwa, fatar jiki, bayyanar gumi mai sanyi, tachycardia, bugun zuciya. Rashin hypoglycemia mai zurfi na iya haifar da lalacewar tsarin mai juyayi, don haka yana da mahimmanci don taimakawa mai ciwon sukari a cikin lokaci.

A cikin halayen da ba kasafai ba, mai haƙuri yana da rashin lafiyan jiyya ga ƙwayar, wanda ke haɗuwa da tasirin fata mai narkewa, angioedema, bronchospasm, hauhawar jijiya, girgiza, wanda kuma haɗari ne ga mutane.

Bayan allurar insulin, magungunan rigakafi zuwa abu mai aiki na iya samarwa. A wannan yanayin, ya zama dole don daidaita tsarin jigilar magunguna don kawar da haɗarin haɓakar hypo- ko hyperglycemia. Da wuya, a cikin masu ciwon sukari, dandano na iya canzawa, a lokuta da ƙarancin yanayi, ayyukan gani na wucin gadi ne sakamakon canji cikin abubuwan gani na tabarau na ido.

Yawancin lokaci, a cikin allura, masu ciwon sukari suna haɓakar lipodystrophy, wanda ke rage jinkirin shan ƙwayoyi. Don guje wa wannan, kuna buƙatar canza wurin yau da kullun don yin allura. Hakanan, redness, itching, soreness na iya bayyana akan fatar, wannan yanayin na ɗan lokaci ne kuma yawanci yakan ɓace bayan kwanaki da yawa.

• Ba za a yi amfani da insulin Lantus tare da tashin hankali ga glargine mai aiki ko wasu abubuwan taimako na miyagun ƙwayoyi ba. An haramta amfani da miyagun ƙwayoyi don amfani a cikin yara 'yan shekaru shida, kodayake, likitan na iya ba da tsari na musamman na maganin SoloStar, wanda aka yi nufi ga yaron.
• Yakamata a yi taka tsantsan yayin aikin insulin yayin ciki da shayarwa. Yana da mahimmanci kowace rana don auna sukari na jini da sarrafa hanyar cutar. Bayan haihuwa, ya zama dole don daidaita sashi na maganin, tunda ana rage bukatar insulin a wannan lokacin.

Yawancin lokaci, likitoci suna ba da shawarar yayin daukar ciki tare da ciwon sukari don yin amfani da wani analog na insulin na dogon lokaci - maganin Levemir.

Game da yawan abin sama da ya kamata, an dakatar da matsakaiciyar jini ta hanyar daukar samfuran da suka hada da abubuwan carbohydrates cikin sauri. Bugu da ƙari, tsarin kulawa yana canzawa, an zaɓi abinci mai dacewa da aikin jiki.

A cikin hypoglycemia mai tsanani, ana gudanar da glucagon a cikin intramuscularly ko subcutaneously, kuma ana ba da allurar rigakafi ta mafitar glucose mai yawa.

Ciki har da likita na iya yin amfani da maganin carbohydrates.

Yadda ake yin allurar insulin

Kafin yin allura, kuna buƙatar bincika yanayin katun da aka sanya a cikin alkairin sirinji. Iya warware matsalar ya zama m, mara launi, ba dauke da laka ko abubuwan gani na waje, daidaituwa mai kama da ruwa.

Alkawarin sirinji naura ne wanda za'a iya dashi, don haka bayan allura dole ne a zubar dashi, sake amfani da shi na iya haifar da kamuwa da cuta. Kowane allura ya kamata a yi tare da sabon allurar bakararre, don ana amfani da wannan allura na musamman, don ƙirar alkalami daga wannan masana'anta.

Dole ne a zubar da na'urorin da suka lalace, tare da estancin shakkun cutar ta aiki, ba za a yi allura tare da wannan alkalami ba. A wannan batun, masu ciwon sukari dole ne a koyaushe su sami ƙarin sirinji don maye gurbin su.

1. An cire hatimin kariya daga na'urar, bayan haka alamar an sa a kan tankin insulin tabbas ana duba shi don tabbatar cewa ingantaccen shiri ya kasance. Ana kuma nazarin bayyanar mafita, a gaban laka, ƙwayar baƙin waje ko daidaituwar turbid, ya kamata a maye gurbin insulin tare da wani.
2. Bayan an cire murfin kariya, allurar mai tazara ce a hankali kuma a haɗe take da alƙawirin syringe. Kowane lokaci kuna buƙatar bincika na'urar kafin yin allura. Yana da mahimmanci a tabbata cewa an nuna alamar farko a lamba 8, wannan yana nuna cewa ba'a yi amfani da sirinji ba kafin.
3. Don saita adadin da ake so, maɓallin farawa an cire shi gabaɗaya, bayan haka mai zaɓin kashi ba zai iya juyawa ba. Yakamata a cire murfin waje da na ciki, a kiyaye su har sai an gama aikin, domin bayan allurar, cire allurar da aka yi amfani da ita.
4. Ana riƙe alkalami na syringe ta allura, bayan haka kuna buƙatar sauƙaƙe yatsunku a kan tafkin insulin don iska a cikin kumfa ta iya tashi zuwa allura. Bayan haka, ana danna maɓallin farawa koyaushe. Idan na'urar ta shirya don amfani, ƙaramin digo ya kamata ya bayyana a ƙarshen allura. Idan babu digo, ana sake maimaita siren syringe.

Mai ciwon sukari na iya zaɓar sigar da ake so daga raka'a 2 zuwa 40, mataki ɗaya a wannan yanayin shine raka'a 2. Idan ya zama dole don gudanar da karuwar insulin, ana yin allura biyu.

A kan ma'aunin insulin na saura, zaku iya bincika yawan ƙwayar da aka bari a na'urar. Lokacin da piston na baƙin fata ya kasance a cikin farkon farkon tsiri mai launin, adadin maganin shine 40 PIECES, idan an sanya piston a ƙarshen, kashi shine 20 PIECES. Ana nuna mai zazzage kashi har sai makarar kibiya ya isa yadda ake so.

Don cika alkalami insulin, an ja maɓallin fara allurar zuwa iyaka. Kuna buƙatar tabbatar da cewa an yi amfani da maganin a cikin ƙwayar da ake buƙata. An canza maɓallin farawa zuwa gwargwadon adadin hormone da ya rage a cikin tanki.

Yin amfani da maɓallin farawa, masu ciwon sukari na iya duba nawa ake ɗaukar insulin. A lokacin tabbatarwa, ana kiyaye mabuɗin. Yawan adadin miyagun ƙwayoyi da aka ɗauka za'a iya yin hukunci da shi ta layin ƙarshe da aka gani.

• Dole ne mara lafiyar ya koyi yin amfani da allon insulin a gaba, dole ne kwararrun ma’aikatan insulin su koyar da su a asibitin. Ana saka allurar koyaushe a ƙarƙashin subcutane, bayan haka ana danna maɓallin farawa zuwa iyaka. Idan an matsa maɓallin gabaɗaya, danna mai sauraro zai yi sauti.
• Ana riƙe maɓallin farawa har na 10 seconds, bayan haka za'a iya cire allura. Wannan dabarar allurar tana ba ka damar shigar daukacin maganin. Bayan an yi allura, sai a cire allura daga alkairin da aka zubar kuma ba za ku sake amfani da ita ba. Ana sanya hula mai kariya a allon alkairin.
• Kowane alkalami na insulin yana tare da littafin koyarwa, inda zaku iya gano yadda za'a girka katako yadda yakamata, haɗa allura da allura. Kafin gudanar da insulin, yakamata ya kasance aƙalla sa'o'i biyu a zazzabi a ɗakin. Kar a sake amfani da katako na fanko.

Ana iya adanar insulin Lantus a ƙarƙashin yanayin zafin jiki daga digiri 2 zuwa 8 a wuri mai duhu, nesa da hasken rana kai tsaye. Ya kamata a sanya magungunan ta hanyar isar da yara.

Rayuwar sel ta insulin shekaru uku ne, wanda bayan haka ya kamata a watsar da mafita, ba za a iya amfani da shi don nufin da aka nufa ba.

Analogues na miyagun ƙwayoyi

Magunguna iri ɗaya tare da tasirin hypoglycemic sun haɗa da insulin Levemir, wanda ke da kwalliya sosai. Wannan magani kwatankwacin kwalliya ce ta insulin aikin mutum.

Ana samar da kwayar ta hanyar amfani da kwayar halitta ta halittar DNA ta hanyar amfani da wani irin nau'in Saccharomyces cerevisiae. Levemir an shigar dashi cikin jikin mai ciwon sukari ne kawai a kasa. An ba da umarnin sashi da kuma yawan allura ta likita mai halarta, gwargwadon halayen mutum na masu haƙuri.

Lantus zaiyi magana game da insulin daki-daki a cikin bidiyo a wannan labarin.