Short insulin

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Insulin-gajeran aiki shine takamaiman wakilin rage sukari wanda ke daidaita tsarin karuwar karuwa a jiki.
Abun wannan magani ya hada da tsarkakakken maganin kwayar cutar, wanda baya dauke da wasu abubuwan karawa wadanda zasu tsawaita tasirin sa ga jiki. Groupungiyar gungun masu aikin gajere suna aiki da sauri fiye da sauran, amma jimlar ayyukan su takaice.

Ana samun magungunan intramuscular a cikin gilashin gilashin da aka rufe, an rufe su da masu dakatarwa tare da sarrafa aluminum.

Sakamakon gajerar insulin a jiki yana tare da:

  • hanawa ko ruruta wasu enzymes;
  • kunnawa glycogen kira da hexokinase;
  • tsangwama na lipase yana kunna mai mai.

Matsakaicin ɓoyewa da kwayar halitta ta dogara da yawan glucose a cikin jini. Tare da ƙaruwa a cikin matakin, tafiyar matakai na samar da insulin a cikin ƙwayar ƙwayar cuta yana ƙaruwa kuma, yana magana, tare da raguwa a cikin taro, narkewa yana raguwa.

Short Short insulin Classification

Dangane da yanayin lokacin insulin gajeran aiki shine:


  • Short (mai narkewa, masu tsarawa) insulins - yi bayan gudanarwa bayan rabin sa'a, don haka an ba da shawarar don amfani da su minti 40-50 kafin abinci. Matsakaicin taro na abu mai aiki a cikin ragin jini ya isa ne bayan sa'o'i 2, kuma bayan awanni 6 kawai sai an gano magungunan suna zama a jikin mutum. Short insulins sun hada da ɗan adam mai narkewa ta hanyar asalin halittar mutum, mai narkewa na mutum da kuma naman alade mai narkewa.
  • Ultrashort (ɗan adam, analog) insulins - fara cutar da jiki bayan gudanarwa bayan mintina 15. Hakanan ana samun babban aiki bayan wasu 'yan awanni. Cire cikakke daga jiki yana faruwa bayan sa'o'i 4. Saboda gaskiyar cewa ultrashort insulin yana da ƙarin tasirin ilimin halittar jiki, ana iya amfani da shirye-shiryen da ake da shi don 5-10 mintuna kafin abinci ko kuma nan da nan bayan abinci. Wannan nau'in magani ya haɗa da insulin insulin da analogues na rabin-insulin kwayar ɗan adam.
Ya kamata a lura cewa insulin kwalliyar kwalliya tayi kama da yanayin jiki na jikin mutum yana ƙaruwa da yawan sukari jini bayan cin abinci. Abin da ya sa ya kamata a ɗauki ɗan lokaci kafin ko kuma nan da nan bayan abinci.

Short insulin don ciwon sukari

Insulin na ciwon sukari yana taimakawa hana ci gaban rikicewa, tsawanta tsawon rayuwar mai cutar siga da haɓaka ingancinsa. Hakanan, injections na wannan miyagun ƙwayoyi rage nauyin a kan ƙwayar ƙwayar cuta, wanda ke ba da gudummawa ga maido da ɓangaren ƙwayoyin beta.

Ana iya samun sakamako iri ɗaya tare da nau'in ciwon sukari na 2 tare da ingantaccen aiwatar da shirin jiyya da bin tsarin likita da shawarar. Hakanan dawo da sel beta kuma yana yiwuwa tare da ciwon sukari na 1 kawai idan an yi gwajin cutar a cikin lokaci kuma an dauki matakan likita ba tare da bata lokaci ba.
Yawanci, ana sarrafa maganin ta intramuscularly ko subcutaneously tare da sirinji da aka tsara musamman don insulin. Ba wai kawai a gaban cutar sankara ba, ana barin gudanar da maganin ta hanyar ƙwayar cuta. An zabi sashi daban-daban, yin la'akari da tsananin cutar, matakin sukari a cikin jiki da kuma yanayin yanayin mai haƙuri.

An wajabta allurar insulin a cikin allurai 2-3 a kowace rana rabin sa'a kafin abinci. Yawancin maganin yana daga raka'a 10 zuwa 40 kowace rana.
Tare da kamuwa da cutar sankara, ana buƙatar adadin ƙwayar cuta mai yawa: don ƙirar subcutaneous - daga 100 PIECES da mafi girma, da kuma don gudanarwar cikin ciki - har zuwa 50 PIECES kowace rana. Don lura da masu cutar sikila, ana yin lissafin adadin insulin daidai da tsananin ƙwayar cuta. A wasu halaye, ba a buƙatar adadi mai yawa na wakili na hormonal, ana ba da shawarar gabatar da ƙananan allurai, amma mafi yawan lokuta.

M Yan adawar da Contraindications

Ba a ba da shawarar insulin don amfani da:

  • maganin ciwon huhu
  • hepatitis
  • fitar
  • decompensated cututtukan zuciya,
  • cutar dutsen koda
  • rauni na raunuka na yankin na ciki da kuma duodenum.

Babban halayen da ba daidai ba bayan aiwatar da wakili na hormonal ya faru ne lokacin da ba a bi shawarwarin sashi. Wannan yana haɗuwa da babban haɓaka insulin a cikin jini.

Mafi yawan sakamako masu illa sun hada da:

  • janar gaba daya;
  • karuwar gumi;
  • palpitations
  • ƙara yawan salivation;
  • farin ciki.

A cikin lokuta masu tsanani na haɓaka mai mahimmanci a cikin kwayar halittar jini a cikin jini (idan ba a kula da lokaci na carbohydrates), raɗaɗi na iya faruwa, tare da asarar hankali da ƙwaƙwalwar ƙwayar cuta.

Short da insulin shirye-shiryen insulin

Duk magungunan da ke ɗauke da gajerun abubuwan ɗan adam ko analogues ɗinsu suna da halaye iri ɗaya. Sabili da haka, idan ya cancanta, ana iya maye gurbinsu, lura da sigogi iri ɗaya, tare da buƙatar farawar likita ana buƙatar. Don haka, ƙaramin zaɓi na sunayen insulin gajere kuma masu aiki cikin sauri

Mafi mashahuri da magani gajere aiki su ne:

Actrapid (matsakaicin farashin 380 rubles)
- wanda aka ƙirƙira ta yin amfani da fasahar Saccharomyces cerevisiae ta amfani da fasahar DNA. Tsawon lokacin aiwatar da aiki mai aiki akan jiki an ƙaddara shi da ƙimar shanshi. Ya dogara da sashi, yanki, nau'in ciwon sukari da hanyar gudanarwa. Tasirin maganin yana farawa ne mintina 30 bayan allura. Matsakaicin yawan insulin ana samun shi ne bayan wani lokaci daidai yake da awanni 1.5-3.5 kuma tsawon lokacin aikin sa ya bambanta daga awa 7 zuwa 8.
Humulin (farashin 530 rubles)
- magani ne tare da tasirin hypoglycemic. An haɓaka shi ne bisa ga insulin ɗan adam na rayuwa da abin da ya danganci wakilai na hormonal na gajere ko na matsakaita. Magungunan yana fara aiki bayan gudanarwa a cikin awa daya. Ana samun saurin maida hankali ne bayan sa'o'i 1-3, kuma jimlar tsawon zama a jiki shine 5-8 awanni.
Iletin (matsakaici farashin daga 400 rubles)
- abun da ke ciki na wannan magani ya hada da insulin-zinc naman alade monocomponent. Magungunan yana da ɗan gajeren lokaci da watsawa, saboda ƙimar ƙwayar abu mai aiki. Farkon bayyanar cutar magani yana faruwa ne bayan sa'o'i 2.5, kuma mafi girman tasirin yana daga 7 zuwa 15 hours. Ana cire insulin zinc daga jiki kwana daya bayan gudanarwar.
Shirye-shirye masu araha:
Novorapid (farashi 1700 rub)
- wanda aka kirkira ta amfani da cerevisiae Saccharomyces tare da sauya amino acid tare da aspartic acid. Tsawon lokacin da aka nuna shi ga miyagun ƙwayoyi ya yi gajere fiye da na insulin ɗan adam mai narkewa. Bayan gudanarwa, ayyukan sa yana farawa tsakanin minti 10-20. Matsakaicin matakin a cikin jini ya kai bayan sa'o'i 1-3. Wannan aikin ya kasance bayan allurar har tsawon awanni 3 zuwa 5.
Humalog (matsakaiciyar farashin kundin 550 rubles)
- Rashin daidaituwa na insulin na ɗan adam, wanda ya kasance yana nunawa ta hanyar farawa da sauri da ƙarshen tasiri idan aka kwatanta da kwayoyi masu gajeriyar magana. Saurin tasirinsa ya samo asali ne saboda tsarin halittar motsin kwayoyin humalogue. Bayan allura, wakilin hormonal ya fara shafar jikin mutum bayan minti 15. Ana lura da yawan ganiya bayan minti 30 ko awa 2.5. Ana cire ta bayan awa 3-4.

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