Altar shine wakili na hypoglycemic da ake amfani dashi a cikin cututtukan sukari.
Sunan kasa da kasa mai zaman kansa
Glimepiride.
Altar shine wakili na hypoglycemic da ake amfani dashi a cikin cututtukan sukari.
ATX
Lambar ATX ita ce A10BB12.
Saki siffofin da abun da ke ciki
Ana samun kayan aiki a cikin kwamfutar hannu. Allunan na iya ƙunsar 1, 2 ko 3 na abubuwa masu aiki. Babban kayan aiki na maganin shine glimepiride.
Fakitin na iya haɗawa da allunan 30, 60, 90 ko 120 a cikin blister. Blaya daga cikin kumburi ya ƙunshi allunan 30.
Aikin magunguna
Abubuwan da ke aiki na miyagun ƙwayoyi suna da tasirin hypoglycemic. Ana amfani dashi don rage sukari na jini a cikin marasa lafiya da ke fama da rashin lafiyar insulin-insulin-da ke fama da rashin lafiyar insulin.
Ana amfani da Altar don rage sukarin jini a cikin marasa lafiya da ke fama da rashin lafiyar insulin-da ke fama da rashin lafiyar insulin.
Kayan aiki yana aiki akan sel beta na pancreas, suna ba da gudummawa ga sakin insulin daga gare su. A ƙarƙashin tasirin glimepiride, beta-sel suna lura da glucose. Sun fi aiki da martani ga karuwar matakan sukari na jini.
Increasearuwar ƙwayar insulin yana faruwa ne saboda haɓakar sufuri ta tashoshin ATP-dogara da ke cikin ƙwayoyin sel na pancreatic.
Toari ga tasiri kan sakin insulin, glimepiride yana ƙara haɓaka ƙwaƙwalwar sel zuwa wannan hormone. Abubuwan da ke amfani da maganin suna hana amfani da insulin a cikin hanta.
Pharmacokinetics
Lokacin da aka shiga cikin, bioavailability na glimepiride kusan 100%. Amfani da abu mai aiki yana faruwa ta hanjin mucosa. Ayyukan sha da yawan yaduwa a cikin jiki yana da cikakken yanci daga cin abinci.
Ana lura da mafi girman tasiri a cikin jini zuwa sa'o'i 2-3 bayan shan magani. Rarraba abu mai aiki a cikin jiki yana faruwa ta hanyar da aka ɗauka yana ɗaure zuwa peptides plasma. Yawancin magunguna suna ɗaure wa albumin.
Rabin rayuwar glimepiride ya yi awowi 5 zuwa 8. Ficewar cikin kayan yana faruwa ne ta hanjin kodan (kimanin 2/3). Wani adadin kashin da ke aiki zai toshiya cikin hanji (kusan 1/3).
Yin amfani da miyagun ƙwayoyi na dogon lokaci baya haifar da tarin abubuwan da ke aiki a cikin jiki.
Yin amfani da miyagun ƙwayoyi na dogon lokaci baya haifar da tarin abubuwan da ke aiki a cikin jiki. Pharmakoketiket na miyagun ƙwayoyi suna da alaƙa da jinsi da shekarun mai haƙuri.
Thanasa da sauran rukuni na marasa lafiya, ana lura da yawan haɗarin glimepiride a cikin jini a cikin mutanen da ke da ƙananan matakan creatinine. Wannan gaskiyar na iya danganta ta da cirewar kayan aiki mai aiki.
Alamu don amfani
An wajabta magungunan don maganin nau'in ciwon sukari na 2 na mellitus (wanda ba shi da insulin). Ana iya amfani da shi daban-daban kuma a hade tare da sauran hanyoyi. An ba da alama ga marasa lafiya waɗanda yanayinsu bai daidaita ta hanyar motsa jiki ba da kuma maganin abinci.
Contraindications
Contraindications wa alƙawarin wannan kayan aikin sune:
- kasancewar mutum ya sanya kansa cikin abubuwan da ya kunsa;
- kasancewar a cikin tarihin maganganu na rashin kwanciyar hankali ga abubuwan da suka samo asali na maganin sulfonylurea;
- nau'in ciwon sukari na 1;
- ketoacidosis;
- cocin ketoacidotic;
- matsanancin rauni na koda;
- gazawar koda a lokacin lalata.
Yadda ake ɗaukar Altar
Tare da ciwon sukari
An ba da shawarar hada shan magungunan tare da isasshen tsari na motsa jiki da kuma maganin abinci. Gudanar da nauyi mai haƙuri yana taka muhimmiyar rawa wajen daidaita daidaiton metabolism a cikin nau'in ciwon sukari na 2. Hakanan wajibi ne don saka idanu akan matakan glucose a cikin jini.
Sigar farko na miyagun ƙwayoyi shine 1 MG kowace rana. Idan wannan kashi ya isa ya kula da matakin glucose a matakin al'ada, to kuwa ana ci gaba da amfani dashi gaba.
Tare da rashin isasshen tasiri na kashi na farko, sannu a hankali yana ƙaruwa. Na farko har zuwa 2 MG, sannan har zuwa 3 MG ko 4 MG. Matsakaicin adadin yau da kullun shine 6 MG. Increasearin haɓaka ba shi da amfani saboda ba zai ƙara tasirin aikin ba.
An bada shawara don shan kwayoyi 1 sau ɗaya kowace rana. Ana yin wannan da safe, kafin ko lokacin abinci.
Bayan an gama karbar liyafar, kar a sha kashi biyu a rana mai zuwa. Wannan baya biyan diyyar da aka rasa.
Dole ne a hadiye allunan tare da isasshen ruwa.
Sakamakon gaskiyar cewa glimepiride yana ƙaruwa da hankalin ƙwayoyin mahaifa zuwa insulin, ana iya buƙatar rage sashi a bayan wani lokaci na gudanarwa. Ana iya aiwatar da bita game da tsarin aikin sashi tare da canzawa a cikin nauyin mai haƙuri.
Idan adadin maganin na yau da kullun bai isa isasshen ikon sarrafa matakan glucose ba, ana wajabta yin insulin lokaci guda. Da farko, an tsara mafi ƙarancin ƙwayar hormone, wanda a hankali zai iya ƙaruwa.
Sakamakon sakamako na Altara
A wani bangare na bangaren hangen nesa
Gabobin hangen nesa na iya amsawa ga magani tare da bayyanar raunin gani na lalacewa, wanda ya haifar da hawa da sauka a cikin sukarin jini.
Gabobin hangen nesa zasu iya amsa magani tare da bayyanar raunin gani na canzawa.
Daga tsoka da kashin haɗin kai
Rashin rauni na tsoka na iya faruwa a sashin musculoskeletal, dalilin shi shine tasirin hypoglycemic na miyagun ƙwayoyi.
Gastrointestinal fili
A cikin lokuta mafi wuya, zawo, amai, amai, bloating, jin zafi a cikin yankin na epigastric na iya faruwa. Kwayar hepatobiliary na iya amsawa ta hanyar haɓaka matakin aiki na enzymes hanta, bayyanuwar jaundice da stagnation na bile.
Hematopoietic gabobin
Kwayoyin Hematopoietic na iya amsawa ga magani tare da bayyanar leukopenia, raguwar adadin ƙwayoyin ja a cikin jini, granulocytopenia, anemia. Duk canje-canje a hoton hoton ana iya juyawa.
Tsarin juyayi na tsakiya
Idan hauhawar jini ya faru, bayyanar rauni, nutsuwa, da saurin gajiya na iya faruwa.
Sakamakon sakamako na miyagun ƙwayoyi na iya faruwa a wani ɓangaren tsarin juyayi na tsakiya a cikin nau'in nutsuwa.
Daga tsarin numfashi
Take hakki bai taso ba.
A ɓangaren fata
Abubuwan da suka shafi fatawar fata, itching, urticaria, daukar hoto, fatar fata.
Daga tsarin kare jini
Ba'a lura da sakamako masu illa.
Daga tsarin zuciya
Wataƙila bayyanar hypotension, karuwa a zuciya.
Daga gefen metabolism
Hyponatremia, hypoglycemia.
Cutar Al'aura
Tsarin rigakafi na iya amsawa ga miyagun ƙwayoyi tare da anaphylaxis, halayen rashin lafiyan, bayyanar vasculitis, haɓakar hypotension har zuwa yanayin girgizawa.
Lokacin ɗaukar Altar, akwai haɗarin raunin gani na ɗan lokaci, wanda zai iya zama haɗari yayin tuki.
Tasiri kan ikon sarrafa abubuwan inji
Ba a gudanar da nazarin sakamakon tasirin kwayar ba a cikin yawan amsawa da maida hankali. Sakamakon canji a cikin yawan ƙwayar glucose na plasma a cikin marasa lafiya na masu ciwon sukari, akwai haɗarin rauni na gani na ɗan lokaci da sauran raunin da zai iya haifar da yanayi mai haɗari lokacin tuki.
Ana iya kiyaye aminci yayin aiwatar da ayyuka masu rikitarwa waɗanda ke buƙatar ƙara yawan faɗakarwa, ta hanyar auna matakan glucose akai-akai. Tare da ƙaruwa da yawa ko raguwa, ana bada shawara don ƙin aiwatar da waɗannan ayyukan na ɗan lokaci.
Umarni na musamman
Yi amfani da tsufa
Tsofaffi mutane suna da haɓakar haɗarin hauhawar jini. Suna buƙatar yin hankali musamman yayin aikin jiyya.
Aiki yara
Babu wadataccen kwarewa game da amfani da miyagun ƙwayoyi a cikin marasa lafiya na wannan rukuni. Idan ana buƙatar magani ga mutane 'yan ƙasa da shekara 18, ya kamata a zaɓi ƙarin magani mafi dacewa.
Amfani da barasa
Ba'a ba da shawarar a hada shan magungunan tare da barasa ba. Wannan na iya haifar da karuwa ko raguwa a cikin tasirin hypoglycemic na glimepiride.
Aikace-aikacen aiki mara kyau
Shan miyagun ƙwayoyi don ƙarancin rashin lafiyar koda ne. Mutanen da ke da laushi zuwa matsakaici na karancin ƙarfi yakamata suyi taka tsantsan yayin aikin jiyya.
Amfani don aikin hanta mai rauni
Rashin aikin aikin hepatic lokaci ne don ƙarin saurin kulawa da matakan enzyme na hanta yayin jiyya. Tare da lalatawar hepatobiliary mai tsanani, ya kamata a watsar da maganin glimepiride.
Yawan Alta
Babban alamar nuna yawan zubar jini shine raguwa mai yawa a matakan glucose. A wannan yanayin, rauni mai zurfi, tashin zuciya, amai, sha, da hankali na damuwa. Girma, rashin bacci, rikicewar tsarin endocrine na iya bayyana. Rashin yawan glucose mai zurfi yana bayyana kanta a cikin rikicewar tashin zuciya, rage sautin jijiyoyin bugun gini, tashin zuciya, da kuma coma.
Ana aiwatar da bayyanar cututtuka na yawan zubar da jini ta amfani da lalacewar ciki, da amfani da matsafa.
Idan mai haƙuri yana sane, ana bashi 20 g na sukari da bakinsa. Game da asarar hankali da sauran rikice-rikice masu tsanani, maganin allurar 20% zuwa 100 ml an allurar dashi. Wataƙila subcutaneous management na glucagon. Bayan mai haƙuri ya dawo da hankali, ana bashi 30 g na glucose a baki kowace sa'o'i 2-3 na kwanaki 1-2 na gaba. Bayan magani, ana kula da glycemia.
Yin hulɗa tare da wasu kwayoyi
Ayyukan glimepiride, wanda shine babban aikin maganin, ya dogara da matakin ayyukan cytochrome P450 2C9. Tare da haɗuwa da glimepiride tare da wakilai waɗanda ke hana ko kunna wannan cytochrome, ƙarfin aiki ko raunana tasirin hypoglycemic na miyagun ƙwayoyi yana yiwuwa.
Tare da haɗuwa da glimepiride tare da wasu jamiái, ƙarfin aiki ko raunana tasirin hypoglycemic na miyagun ƙwayoyi yana yiwuwa.
Ana lura da ƙwayar ƙwayar ƙwayar ƙwayar ƙwayoyi yayin da aka hada magungunan tare da wasu magunguna na pyrazolidines, sauran magungunan antidiabetic, quinolones, mai juyayi, insulin, adenosine yana canza masu inzyme, cyclophosphamide, fibrates.
Tasirin hypoglycemic na glimepiride ya raunana ta hanyar thiazide diuretics, glucocorticosteroids, laxatives, glucagon, barbiturates, tausayi, mai juyayi, rifampicin.
Masu hana Biya-blockers da kuma maganin hana karuwan kwayoyin tsufa suna iya amfani da karfin jiki da kuma raunana tasirin maganin.
Glimepiride na iya haɓaka ko rage sakamakon asalin abubuwan coumarin.
Yi amfani da lokacin daukar ciki da lactation
Bayanai game da amfani da miyagun ƙwayoyi a cikin wannan rukuni na marasa lafiya basu isa ba. Ana ba wa matan da ke da nau'in ciwon sukari na 2 izinin shawarar likita kafin su fara yin juna biyu. Mafi sau da yawa, ana ba da shawarar irin waɗannan marasa lafiya don canzawa zuwa ilimin insulin.
Babu bayanai game da shigarwar abu mai aiki cikin madara. Dangane da haɗarin yiwuwar haɓakar ƙwararrakin ƙwayar cuta a cikin yaro, an ba da shawarar cewa a canza shi zuwa abincin da ke cikin wucin gadi.
Analogs
Analogs na wannan kayan aikin sune:
- Amaryl;
- Glemaz.
Magunguna kan bar sharuɗan
An sake su bisa ga umarnin likita.
Zan iya siye ba tare da takardar sayan magani ba
A'a.
Farashi
Kudin ya dogara da wurin da aka siya.
Yanayin ajiya na miyagun ƙwayoyi
Dole ne a adana shi a cikin busassun a zazzabi baya wuce + 30 ° С.
Ranar karewa
Magungunan sun dace don amfani a cikin shekaru 2 daga ranar da aka sake su. Ba da shawarar ƙarin amfani ba.
Mai masana'anta
Rijistar miyagun ƙwayoyi mallakar arinungiyar Ayyuka ta Duniya ta Menarini Luxembourg. Akwai masana'antu na masana'antu a Indiya.
Nasiha
Victor Nechaev, masanin kimiyar endocrinologist, Moscow
Kayan aiki mai amfani wanda zai ba ka damar kula da ingantaccen taro na glucose a cikin marasa lafiya da ke dauke da ciwon sukari na 2. Idan kun yi daidai da tsarin da aka ba da shawarar ku kuma sarrafa matakin glucose, sakamako masu illa a yayin jiyya suna da wuya.
Zan kuma bayar da shawarar na lokaci-lokaci saka idanu akan ayyukan hanta na hanta. Wannan zai taimaka don kauce wa canje-canje a cikin aikin magungunan ƙwayar cuta, wanda zai iya haifar da hypoglycemia. Gwajin lokaci na zamani zai zama kyakkyawan rigakafin kamuwa da cutarwa. Idan alamu sun canza, likitan zai iya daidaita sashi ko ya soke magani na ɗan lokaci.
Ina ba da shawarar wannan kayan aiki ga duk marasa lafiya da ke fama da ciwon sukari da ba na insulin ba. Wannan kayan aiki mai araha ne kuma mai tasiri. Kyakkyawan kulawar glycemic don kuɗi kaɗan.
Marina Oleshchuk, endocrinologist, Rostov-on-Don
Gliperimide yana bi da aikin sosai. Kayan aiki yana ƙarfafa sakin insulin kuma yana taimaka wa jiki ya sha shi sosai. Na sanya shi ga marasa lafiya waɗanda ba za su iya sarrafa abubuwan glucose a cikin jini ba tare da taimakon maganin abinci da motsa jiki ba.
Rashin ciwon insulin-wanda yake dogaro yana faruwa saboda dalilai da yawa, daga cikinsu akwai masu kiba sosai. Ina ba da shawarar cewa irin waɗannan mutane su haɗu da shan wannan magani tare da aikin jiki da abinci mai dacewa. Ba zai zama superfluous don bincika ayyukan glandar thyroid ba, wanda zai iya ba da gudummawa ga samun nauyi.
Ga wasu marasa lafiya, kawai maganin glimepiride da insulin ya dace. Don kula da matakan glucose na yau da kullun, tabbatar da tattaunawa tare da endocrinologist lokaci-lokaci. Awararren masani ne kaɗai zai zaɓi isasshen magani wanda zai ba ka damar jagorancin rayuwa mai aiki, manta game da cutar sankara.
Lydia, ɗan shekara 42, Kislovodsk
Na dauki wannan magani kimanin shekara 5. Komai yayi kyau. Babu sakamako masu illa idan kun bi jiki. Kawai ka lura da matakin sukari akan lokaci, kuma komai zai yi kyau. Amma bayan wani lokaci, jinina ya fara lalacewa a hankali.
A bara, ta fara lura da cewa glucose jini a hankali yana ƙaruwa. Ta dauki matsakaicin adadin maganin glimepiride, saboda haka dole ne in ga likita. Ta ci gaba da maganin don ganin ko sukari zai kara ƙaruwa. Ya juya cewa jiki a tsawon shekaru na amfani da shi ya saba da miyagun ƙwayoyi kuma ba ya amsa magani. Dole na canza zuwa sabon kayan aiki.
Zan iya ba da shawarar wannan magani ga duk mutanen da ke da ciwon sukari na 2, amma lokaci-lokaci ziyarci likita don tabbatar da cewa babu wani jaraba.
Peter, dan shekara 35, St. Petersburg
Kyakkyawan kayan aiki tare da isasshen farashin. Ina ɗaukar fiye da shekara guda, don haka babu korafi. Kodayake na karanta game da mummunan tasirin sakamako a cikin umarnin, ban sadu da su ba a aikace.Ina ɗaukar ƙananan ƙwayar glimepiride, don haka ba zan iya faɗi yadda marasa lafiya suke ji ba, waɗanda ke taimaka wa babban allurai kawai. Zan iya ba da shawarar wannan magani ga duk wanda ke fama da ciwon sukari wanda ba shi da insulin-kai. Kula da matakan glucose kuma je zuwa likita akan lokaci, to wannan magani zai gudana ba tare da wani nuances ba.
