Mepharmil halin haɓakar tasirin cuta ne. Ana amfani dashi a cikin lura da ciwon sukari na mellitus a cikin nau'in na biyu. Idan kun bi abinci, yana da tasiri mai sauri kuma mai ɗorewa akan samar da glucose.
Sunan kasa da kasa mai zaman kansa
Metformin.
ATX
Lambar ATX: A10V A02.
Ana amfani da Mepharmil a cikin lura da ciwon sukari na mellitus na nau'in na biyu.
Saki siffofin da abun da ke ciki
Akwai shi a cikin allunan da ke ɗaukar hoto. Babban sashi mai aiki shine metformin hydrochloride, sashi na 500, 850 ko 1000 mg akan kwamfutar hannu 1. Substancesarin abubuwa:
- Allunan 500 da 850 MG: sodium sitaci glycolate, masara sitaci, povidone, magnesium stearate, silicon dioxide. Membrane fim ɗin ya ƙunshi hypromellose, polyethylene glycol, talc, propylene glycol da titanium dioxide. Allunan suna zagaye, fararen fata ko cream, an zana su a gefuna.
- Allunan 1000 MG: magnesium stearate, povidone. Filin membrane ana yinsa ne ta hanyar hypromellose, polyethylene glycol 6000 da 400. Allunan masu launin kwalliya sune farin ko cream a launi, tare da layin rarrabuwa a ɓangarorin biyu.
Aikin magunguna
Yana nufin biguanides tare da tasirin sakamako na antihyperglycemic. Ana saukar da glucose duka a kan komai a ciki kuma bayan cin abinci. Insulin insulin baya karuwa, ba a lura da sakamako na hypoglycemic sakamako ba.
Haramcin ayyukan gluconeogenesis yana faruwa, yayin da rage yawan glucose a cikin hanta ya ragu. Halin hankali na tsarin tsoka zuwa insulin yana ƙaruwa, yin amfani da glucose a cikin kyallen mahaifa yana inganta. Cutar da sugars a cikin hanji yana sauka a hankali.
Abunda yake aiki shine yake karfafa kwayar glycogen a cikin sel. Metformin yana inganta haɓakar metabolism. Abubuwan da ke cikin triglycerides da cholesterol an rage su. Tare da amfani da tsawan lokaci a cikin marasa lafiya, nauyin jiki a hankali yana raguwa.
Ana samun magungunan a cikin allunan, waɗanda ke rufe da murfin fim.
Pharmacokinetics
Ana lura da mafi girman maida hankali 2 sa'o'i bayan shan kwayoyin. Metformin ya tara a cikin hanta, glandon ciki, kodan, da tsokoki. Rashin ingancin bioavailability da ikon ɗaure zuwa tsarin furotin ana iya sakaci. An cire abubuwan da ke aiki a cikin kusan awa 6 tare da fitsari, ba su canzawa. Metabolites ba sa tsari.
Alamu don amfani
Alamar kai tsaye ga amfani da miyagun ƙwayoyi sune:
- nau'in ciwon sukari na 2 na sukari (tare da rage cin abinci mara kyau da aikin jiki);
- maganin-iska mai rikitarwa tare da insulin don lura da manya, yara daga shekaru 10 da matasa;
- taimako daga rikitarwa na type 2 ciwon sukari a cikin kiba.
Yawancin lokaci ana amfani da maganin don asarar nauyi. Amma an ba da shawarar ɗaukar shi bisa ga alamu kuma cikin ƙayyadadden tsarin kwatancen.
Contraindications
Haramun ne a bada magani don:
- hypersensitivity ga mutum aka gyara;
- mai ciwon sukari mai ciwon sukari;
- precom
- lalacewa aiki na renal;
- rashin ruwa a jiki;
- mummunan cututtukan cututtuka;
- ɓarna da rauni ga zuciya;
- tashin zuciya;
- kwanan nan infarction myocardial;
- gazawar hanta;
- m barasa guba.
Yadda ake ɗaukar mefarmil?
Maganin farko na manya shine 500 ko 850 mg sau biyu a rana bayan cin abinci. Lokacin ƙirƙirar allurai masu girma, ana iya maye gurbin allunan 2 na 500 MG tare da ɗayan a cikin 1000 mg. Matsakaicin adadin yau da kullun kada ya wuce mil 3000, wanda aka kasu kashi uku.
Tare da ciwon sukari
Yawan maganin yau da kullun bai wuce 1000 mg ba. Idan ya cancanta, ana iya karuwa zuwa 2000 MG a kowace rana, a kasu kashi biyu. A wasu yanayi, za a iya rage ko kuma a karu da sashi (wannan ya faru ne saboda hawa da sauka a matakin glucose a cikin jini).
Sakamakon sakamako na Mepharmila
A farkon jiyya, mummunan sakamako na iya faruwa a cikin nau'in tashin zuciya, amai, zawo, asarar ci, da ciwon ciki. Mafi yawan lokuta, waɗannan bayyanar cututtuka suna tafi da kansu kuma basu buƙatar wani magani.
Bugu da kari, maganin yana haifar da irin wannan halayen masu illa:
- cuta cuta na rayuwa;
- take hakkin dandano;
- lactic acidosis;
- rage sha da taro na bitamin B12 a cikin jini;
- tsoka hepatitis;
- aikin lalata hanta;
- fata fitsari tare da itching;
- cututtukan mahaifa.
Urticaria shine ɗayan cututtukan sakamako na shan ƙwayoyi.
Yawancin waɗannan halayen suna tafi da kansu, amma a wasu yanayi zai zama dole a daidaita sashi ko kuma a soke maganin gaba ɗaya.
Tasiri kan ikon sarrafa abubuwan inji
Monotherapy tare da metformin baya haifar da ci gaban hypoglycemia, bi da bi, kuma baya haifar da raguwa a cikin taro. Za'a iya fitar da motoci tare da wannan magani, kuma yawan motsi baya raguwa.
Yakamata a yi taka tsantsan yayin ɗaukar wannan magunguna tare da sauran magunguna na hypoglycemic a cikin wani mawuyacin hali saboda yiwuwar haɓakar ƙwayar cuta, wanda ke shafar taro.
Umarni na musamman
Sakamakon tarin metformin, lactic acidosis yana faruwa. Yana bayyana kanta a cikin nau'in tsananin raɗaɗi, raunin dyspeptik, asthenia. Ya kamata a lura da hankali cikin mutanen da ke fama da rauni na aiki da hepatic. Tare da kowane canje-canje a cikin yanayin kiwon lafiya, ana buƙatar daidaita sashi na kayan magani. Sau da yawa megaloblastic anaemia da lactic acidosis suna haɓaka.
Yakamata a yi taka tsantsan lokacin amfani da wannan magani a cikin tsofaffi.
Haɗewar yin amfani da girke-girke na vegan da magani na gargajiya tare da metformin mai yiwuwa ne, amma a ƙarƙashin kulawa mai ƙoshin lafiya ne. Madadin girke-girke na taimakawa kawai don kiyaye tasirin sakamako na maganin, amma ba zai iya zama tushen sa ba.
Yi amfani da tsufa
Yakamata a yi taka tsantsan yayin amfani da wannan magani a cikin tsofaffi, saboda tabbas suna iya haɓaka haɓakar hypoglycemia. Wajibi ne a lura da duk canje-canje a cikin sakamakon gwajin don daidaita yanayin maganin a cikin lokaci.
Aiki yara
Kodayake babu wata hujja cewa abu mai aiki a cikin kowace hanya yana shafar lokacin balaga, ba a ba da shawarar sanya magunguna ga yara ba. Ana amfani da irin wannan magani ne a lokuta na musamman bayan tabbacin cutar sankarar cututtukan type 2.
Yi amfani da lokacin daukar ciki da lactation
Babban haɗari ga tayin ana samun shi cikin mata masu juna biyu da ke fama da cutar sankara, saboda saboda shi, wasu asirin haihuwa na iya haifar da haɓaka. Koyaya, shan allunan na Mefarmil baya tasiri zafin su. Jiyya yayin gestation mai yiwuwa ne kawai a karkashin tsananin kulawa na likita tare da sanya idanu akai-akai na glucose jini.
Shan Allunan Mefarmil baya shafar tayin nan gaba.
Kodayake magani ba ya cutar da jariri ba, ya ratsa cikin madara mai nono da isasshen adadi mai yawa, don haka ya fi kyau a ƙi shayar da nono na tsawon lokacin shan magani tare da miyagun ƙwayoyi.
Aikace-aikacen aiki mara kyau
Tare da cututtukan koda, ana buƙatar daidaitawa akai-akai don yin la'akari da hawa da sauka a cikin sukari na jini.
Amfani don aikin hanta mai rauni
A cikin lalacewar hanta na hanta, ana buƙatar daidaita sashi na kayan magani. Tare da kazanta lalacewa a cikin sakamakon gwajin hanta, an wajabta mafi ƙarancin tasiri akan ƙwayar cuta. Idan ba ta samar da sakamako mai warkewa ba, zai fi kyau a ƙi irin wannan jiyya.
Yawan adadin Mefarmil
Tare da kashi ɗaya na maganin a kan 850 MG, ba a lura da alamun hypoglycemia ba. Zai yiwu ci gaban lactic acidosis. Wannan yanayin gaggawa ne wanda ke buƙatar jiyya mai haƙuri kawai. Yana yiwuwa a cire metformin da lactate daga jiki ta hanyar hemodialysis.
Yana yiwuwa a cire metformin da lactate daga jiki ta hanyar hemodialysis.
Yin hulɗa tare da wasu kwayoyi
Yin amfani da haɗin gwiwa tare da wakilai na aidin suna haifar da bayyanar rashin cin nasara na koda. X-ray bambanci wakilai tsokani da ci gaban lactic acidosis.
Tare da taka tsantsan, ana bada shawara a sha Allunan tare da wakilai na antihyperglycemic da abubuwan juyayi, da kuma abubuwan nicotinic acid. A wannan yanayin, kuna buƙatar lura da matakin glucose a cikin jini koyaushe, daidaita sashi don la'akari da canje-canje a cikin lafiyar gaba ɗaya.
Diuretics suna ba da gudummawa ga ci gaban lactic acidosis kuma yana haifar da raguwa mai ƙarfi a cikin aikin renal.
Amfani da barasa
Tuntuɓi mai kitse, ethanol yana tsokani haɓakar lactic acidosis kuma yana haifar da ci gaban haɓakar hanta. Sabili da haka, miyagun ƙwayoyi basu dace da barasa ba.
Magungunan ba su dace da barasa ba.
Analogs
Akwai maganganu da yawa da suka dace da kayan aikin yanzu da aikin da aka bayar. Wadannan sun hada da:
- Bagomet;
- Glycometer;
- Glucovin Xr;
- Glucophage;
- Glumet;
- Dianormet;
- Diaformin;
- Insufor;
- Langerin;
- Meglifort;
- Methamine;
- Metfogamma;
- Hexal na Metformin;
- Metformin Zentiva;
- Metformin Astrapharm;
- Metformin Teva;
- Metformin Sandoz;
- Metformin MS;
- Tafiya;
- Siofor;
- Zukronorm.
Magunguna kan bar sharuɗan
Ana samun sa ne kawai bayan gabatar da takardar sayen magani.
Zan iya saya ba tare da takardar sayan magani ba?
Ba zai yiwu ba.
Farashin Mepharmil
Kudin ya kama daga 120 zuwa 280 rubles. don shiryawa.
Yanayin ajiya na miyagun ƙwayoyi
Adana kawai a cikin ainihin fakitin, a cikin duhu da bushe wuri inda yara ba za su iya isa ba, a yanayin zafi da bai wuce + 25 ° C ba.
Ranar karewa
Shekaru 3 daga ranar ƙirar da aka nuna akan marufi na asali. Kada kuyi amfani a ƙarshen wannan lokacin.
Rayuwar shiryayye na miyagun ƙwayoyi shine shekaru 3 daga ranar ƙirar da aka nuna akan marufi na asali.
Mai masana'anta
PJSC "Kievmedpreparat", Kiev, Ukraine. A Rasha, ba a samar da wannan kayan aikin ba.
Nazarin Mepharmil
Lyudmila, dan shekara 45, Arkhangelsk
Na daɗe ina fama da ciwon sukari na 2. Na riga na gwada magunguna da yawa, amma ba su da tasirin gaske. Likitan ya ba da shawarar daukar allunan Mefarmil. Sakamakon magani ya gamsu. Shan maganin ba ya haifar da wata matsala, saboda ba kwa buƙatar allurar allura, kuma wannan ya dace, musamman ga mai aiki. Na sha kwaya kuma cikin nutsuwa. Ban ji wani sakamako ba daga kaina.
Ruslan, dan shekara 57, Omsk
Wannan magani bai dace ba. Wataƙila saboda shi ma ya ɗauki diuretics, amma zafin fitsari na jiki ya fara. Janar yanayin ya kara ta'azzara. Kashegari, raɗaɗi ya fara, matsanancin ciwon kai ya bayyana, ciwon ciki ya karu, duk alamun bayyanar maye. Likita ya ce wannan shi ne yadda na nuna lactic acidosis. Dole na canza miyagun ƙwayoyi.
Sergey, dan shekara 34, Samara
Kwanan baya, an gano ni da ciwon sukari na type 2. Ni mai kiba ne, wanda ya zama ɗaya daga cikin sanadin cutar. Likita ya ba da allunan Mepharmil. Tare da abinci da kwaya, nauyi ya fara raguwa. Yanzu yana da mahimmanci a kiyaye shi a matakan al'ada. Yanayin yanayin gaba ɗaya ya zama mafi kyawu. Powerarin ƙarfi da ƙarfi sun bayyana. Bugu da kari, shan kwaya ya fi dacewa fiye da yin allura. Yayinda na gamsu da lura da wannan maganin.
