Mene ne lactic acidosis kuma me yasa yake da haɗari?

Don aiki na yau da kullun na jiki, daidaitaccen duk abubuwan haɗinsa wajibi ne - hormones, abubuwan jini, tsotse, enzymes.

Jawabi a cikin abun da ke faruwa ya faru ne sakamakon take hakkin metabolism da haifar da mummunan sakamako ga mutane.

Acidosis yanayi ne wanda ake lura da karuwar abubuwan acid a cikin jini.

Yanayin alkaline na dan kadan yanayin jini yana canzawa ta fuskar kara girman acidity. Wannan baya faruwa a cikin lafiyar jiki, amma sakamakon halaye daban-daban na cututtukan cuta.

Mene ne lactic acidosis?

Lactic acidosis (lactic acidosis) ana kiranta karuwa a cikin abubuwan lactic acid a cikin jini. Wannan yakan haifar da wuce gona da iri da kuma fitowar jiki daga jiki ta hanjin kodan da hanta. Wannan wani yanayi ne da ba kasafai yake faruwa ba, wanda yake sakamakon wasu cututtuka.

Lactic acid a cikin jiki samfuri ne na aikin glucose. Tsarin sa baya buƙatar oxygen, an kafa shi yayin metabolism na anaerobic. Mafi yawan acid na shiga jini daga tsokoki, kasusuwa, da fata.

Nan gaba, lactates (salts na lactic acid) ya kamata ya shiga cikin sel da hanta da hanta. Idan wannan rushe wannan tsari, abubuwan da ke cikin acid suna ƙaruwa cikin sauri kuma yana gudana. Ana yin lactate mai wucewa saboda tsananin damuwa na rayuwa.

An lura da ƙwaƙwalwar ƙwaƙwalwa tare da haɓaka kira da rikicewa na kawar da cuta - cututtukan koda, ƙwaƙwalwar ƙwayar jan jini.

Gudanar da lactates ya zama dole ga 'yan wasa, tun da haɓakarsu mai yiwuwa ne tare da manyan kaya.

Lactic acidosis yana da nau'i biyu:

1. Nau'in A - wanda ya haifar da rashin isashshen oxygen oxygen kuma yana faruwa ne sakamakon matsalolin numfashi, cututtukan zuciya, anemia, guba.
2. Nau'in B - yana faruwa ne saboda samuwar da ba ta dace ba da kuma fitar da acid ɗin. Lactic acid ana samara da yawa kuma ba'a amfani dashi a cikin cututtukan mellitus, cututtukan hanta.

Lactic acidosis gaba daya yana haifar da:

• cututtukan oncological (lymphomas);
• uncompensated ciwon sukari mellitus;
• lalacewar koda koda (mummunan siffofin glomerulonephritis, nephritis);
• ilimin cututtukan hanta (hepatitis, cirrhosis);
• cututtukan kwayoyin halittu;
• guba, ciki har da waɗanda ke haifar da kwayoyi (Metformin, Fenformin, Methylprednisolone, Terbutaline da sauransu);
• mummunan cututtukan cututtuka;
• guba mai guba;
• amo mai rarrafe

Matsakaicin al'ada na lactate / pyruvate a cikin jini (10/1) yana da mahimmanci. Lationetarewa wannan gwargwado a cikin shugabanci na ƙara yawan lactate yana ƙaruwa cikin sauri kuma yana iya haifar da mummunan yanayin mai haƙuri.

An ƙayyade matakin lactate abun ciki ta amfani da bincike na ƙirar ƙwayoyin cuta. Ba a ayyana ƙa'idodin halayen ƙasashen duniya ba, saboda sun dogara ne akan hanyoyin bincike da kayan da ake amfani da su.

Ga manya, mai nuna alamar matakan jini na yau da kullun suna cikin 0.4-2.0 mmol / L.

Siffofin ci gaban Pathology a cikin ciwon sukari

Ofayan manyan dalilai na haɓakar lactic acidosis shine cin zarafin wadatar oxygen, kyallen takarda, saboda abin da metabolism na anaerobic glucose metabolism ke haɓaka.

A cikin ciwo mai tsanani, tare da ƙarin lalacewar kodan da hanta, an rage yawan sufurin oxygen, kuma gabobin da ke da hannu don cire lactates daga jini ba zasu iya jurewa ba.

Lactic acidosis a cikin nau'in ciwon sukari na 2 yana yiwuwa mummunan sakamako na cutar. Wannan rikitarwa yawanci yakan faru ne a cikin tsofaffi marasa lafiya (fiye da shekaru 50) tare da matsalolin jijiyoyin jini, urinary da tsarin narkewa. Lactic acidosis da wuya ya fara shi kaɗai, sau da yawa yana haɗuwa ne da cutar siga.

Abubuwan da ke ba da gudummawa ga ci gaban yanayin:

• lalacewar hanta;
• anemia - rashi baƙin ƙarfe, folic;
• ciki
• ilimin cutar koda;
• babban asarar jini;
• danniya
• cututtukan mahaifa;
• cututtukan oncological;
• ketoacidosis ko wasu nau'ikan acidosis.

Sau da yawa tsokana na lactic acidosis shine amfani da kwayoyi, musamman, biguanides, da yanayin ɓacin rai na ciwon sukari. Biguanides (Metformin) sune jiyya don ciwon sukari.

Yawancin lokaci haɗuwa da abubuwa da yawa suna faruwa. Babban mawuyacin hali na cutar yana haifar da hypoxia na nama na yau da kullun, aikin nakasa na aiki yana haifar da maye.

Bidiyo daga Dr. Malysheva game da Metformin:

Bayyanar cututtuka da kuma bayyanar da yanayin haɗari

Hakanan ana nuna alamun cututtukan lactates a cikin jini - gajiya, gajiya, amai, alamun dyspepsia, tashin zuciya da amai. Wadannan bayyanar cututtuka suna kama da ciwon sukari wanda ba a daidaita shi ba.

Ciwan tsoka zai iya ba da labarin wani lactic acid, kamar bayan aiki mai wahala. Ta wannan hanyar ne ake samun ci gaban lactic acidosis mafi yawan lokuta. Raunin yana kama da myalgic, yana ba kirji. Duk sauran alamun ba takamaiman bayanai ba, saboda haka, ana fassara su ba daidai ba.

Tsarin farawar ɓoyewar lactic acid yana haɓaka da sauri, yanayin haƙuri yana saurin lalacewa. Bayan 'yan awanni sun wuce zuwa cutar mahaifa. A wannan lokacin, rikice-rikice na jiki da yawa suna tasowa - tsakiya da na gefe mai juyayi, numfashi.

Mai haƙuri yana da:

• rikicewar dyspeptic;
• raguwa a cikin fitsari har sai an daina shi;
• hypoxia yana haifar da jin rashin isasshen iska, yawan saurin numfashi yana tasowa (Kussmaul numfashi) tare da sobs da nishi;
• increasedara yawan ƙwaƙwalwar jini tare da ƙirƙirar ƙwanƙwasa jini da kuma yiwuwar haɓakar ƙoshin ƙwayoyin cuta a cikin gabar jiki;
• bugun zuciya rikice rikice, karuwar aikin zuciya;
• asarar daidaituwa, wawa;
• bushe fata, ƙishirwa;
• sauke cikin karfin jini, raguwa a zafin jiki;
• rikicewar tsarin jijiya na gefe yana haifar da tashin hankali da asarar sassauci.

Halin ya bambanta da ketoacidosis yayin rashin warin acetone yayin ƙonewa. Rashin lafiyar Cardiac yana da wuya a gyara tare da kwayoyi. Cutar na ciki na iya haɓaka a cikin 'yan awanni kaɗan.

Taimako na farko da magani

Bayyanar cututtukan lactic acidosis ba su da takamaiman bayani, don haka mai haƙuri yakamata ya yi gwajin jini. Za'a iya bayar da taimako kawai a tsarin asibiti. Wajibi ne a bambance yanayin tare da ketoacidosis da acid uremic.

Ana nuna yanayin lactic acidosis ta:

1. Matakan Lactate sun wuce 5 mmol / L.
2. Rage bicarbonates da pH na jini.
3. Increara tazarar tazara a cikin plasma.
4. Inara yawan narkewa a cikin nitrogen.
5. Abun Ciwon ciki.
6. Rashin acetonuria.

Ba shi yiwuwa a inganta yanayin haƙuri a gida, ƙoƙarin taimakawa ƙarshen mutuwa. Asibiti cikin gaggawa, gwajin lokaci da kuma gano lactic acidosis da sake tayarda hankali na iya dakatar da ci gaban kwayar cutar.

A lokacin jiyya, ana buƙatar manyan matakai biyu - kawar da hypoxia da raguwa a cikin matakin lactic acid da samuwar sa.

Don dakatar da samuwar lactates wanda ba a sarrafa shi ba, yana taimakawa jijiyoyin jijiyoyin wuya tare da iskar oxygen. Don wannan haƙuri, an haɗa su da mai ba da iska. A lokaci guda, ana tsayar da hawan jini.

Yanayi mai mahimmanci don karɓar mai haƙuri daga mummunan yanayin shine gano abubuwan da ke haifar da lactic acidosis da kuma magance cututtukan da suka dace.

Don fitarwa da yawa na lactic acid, ana amfani da hemodialysis.

Don daidaita pH na jini, sodium bicarbonate yana narkewa. Abun shigar sa yayi matukar jinkiri akan sa'o'i da yawa.

A wannan yanayin, pH ya kamata ya kasance ƙasa 7.0. Ana lura da wannan alamar a kowane sa'o'i 2.

A cikin warkarwa, ana amfani da heparin don hana thrombosis, magunguna na kungiyar carboxylase, Reopoliglukin.

Ba a buƙatar gabatarwar insulin ba, ana yawanci amfani dashi a cikin ƙananan allurai drip.

Matsaloli masu yiwuwa, rigakafin

Rikitarwa na lactic acidosis shine coma. Yanayin na iya bunkasa a cikin 'yan awanni. Nasarar magani ya dogara da iyawar ma'aikatan, wanda a cikin lokaci zai tantance haɗarin ga mai haƙuri. Ana kuma buƙatar ƙididdigar gaggawa.

Tare da lactic acidosis, yanayin yana ƙaruwa da sauri - akwai asarar reflexes, raguwar matsin lamba da yawan zafin jiki zuwa 35 °, damuwa na numfashi. Rashin bugun zuciya na iya haifar da lalacewa na zuciya. Haduwa ya zo - mara lafiya ya yi asarar hankali.

Babban hanyar hana lactic acidosis shine rama ciwon sukari. Dole ne a aiwatar da amfani da magungunan da endocrinologist ya tsara bisa ga tsarin da aka tsara. Idan ka rasa shigarwar, baza ku iya rama matsala da ƙarancin ƙwayar cuta ba.

Bai kamata kuyi amfani da shawarar 'yan uwan ​​masu fama da cutar ba, kuma kuyi amfani da magungunan da zasu taimaka masu, ba tare da nadin kwararrun likitanku ba. Marasa lafiya da ciwon sukari kada suyi amfani da kayan abinci na abinci wanda kamfanoni da yawa ke ba da shawarar su.

Wajibi ne a kiyaye sukari tsakanin iyakoki na yau da kullun, a kai a kai a kai ga likitan dabbobi don a dauki gwaje gwaje. Lokacin canzawa zuwa sababbin magunguna, ya kamata ku kula da yanayin ba tare da wucewa ko rage sashi ba.

Yana da mahimmanci a bi abincin da aka tsara, kazalika da jagoranci salon rayuwa mai aiki. Wannan zai taimaka inganta haɓaka metabolism da samarda jini ga gabobin. Hanya mai kyau don kula da lafiya shine maganin ƙoshin lafiya. Hanyar magungunan zamani na ba ka damar adana ciwon sukari ƙarƙashin kulawa.