Don daidaita matsayin glucose a cikin jini, ana amfani da magunguna daban-daban, waɗanda suka haɗa da Merifatin. Magungunan ƙwaƙwalwar ƙwayar cuta yana da contraindications da sakamako masu illa, don haka kafin fara magani, kuna buƙatar ziyarci ƙwararrun masanin kimiyya kuyi nazarin umarnin.
Sunan kasa da kasa mai zaman kansa
Metformin.
Don daidaita matsayin glucose a cikin jini, ana amfani da magunguna daban-daban, waɗanda suka haɗa da Merifatin.
ATX
A10BA02.
Saki siffofin da abun da ke ciki
Ana amfani da miyagun ƙwayoyi a cikin nau'ikan allunan 500 MG, 850 MG da fim mai nauyin 1000 MG. An sanya su cikin guda 10. cikin nutsuwa. Kunshin kwali na iya ƙunsar 1, 2, 3, 4, 5, 6, 8, 9 ko 10 blister. Allunan za'a iya sanya su a cikin gilashi na polymer na guda 15., Inji mai kwakwalwa 30, inji mai kwakwalwa 60., 100 inji mai kwakwalwa. ko kwaya guda 120. Abunda yake aiki shine metformin hydrochloride. Abubuwan taimako sune povidone, hypromellose da sodium stearyl fumarate. Fim ɗin mai narkewa mai ruwa-ruwa ya ƙunshi polyethylene glycol, titanium dioxide, hypromellose da polysorbate 80.
Aikin magunguna
Magunguna magani ne na baki wanda yake da alaƙa da biguanides. Sinadaran da ke aiki suna taimakawa wajen kwantar da gluconeogenesis, kirkirar kitse mai-kyauta da hadawar hada hada-hada da kitse. Godiya ga gudanarwar miyagun ƙwayoyi, masu karɓar mahaɗan sun fi kulawa da insulin kuma an inganta amfanin glucose ta sel. Yawan insulin a cikin jini baya canzawa, amma rabo daga insulin da daurewar insulin ya ragu kuma rashi insulin da proinsulin yana ƙaruwa.
Lokacin da aka nuna shi ga glycogen synthetase, metformin yana inganta haɓakar glycogen. Ayyukanta na da nufin haɓaka ƙarfin zirga-zirgar zirga-zirga a cikin kowane nau'in masu safarar glucose a cikin membrane. Abun yana rage jinkirin shan gulukos a cikin ƙwayar hanji, yana rage adadin LDL, triglycerides da VLDL, yana kuma inganta ƙirar fibrinolytic ta jini, yana hana ƙirar ƙwayar plasminogen mai kunnawa inhibitor. A lokacin jiyya na metformine, nauyin mai haƙuri ya kasance barga ko sannu a hankali yana raguwa zuwa al'ada a gaban kiba.
Tare da yin amfani da abinci lokaci guda, shan maganin yana ragewa.
Pharmacokinetics
Bayan shan kwayoyin, jinkirin da yake cikakke kuma yana cikin tsarin narkewa yana faruwa. An lura da mafi yawan abubuwan abu a cikin jini na jini bayan awa 2.5. Tare da yin amfani da abinci lokaci guda, shan maganin yana ragewa. Abubuwan da ke aiki suna shiga cikin dukkanin kasusuwa na jikin mutum, a zahiri ba tare da ɗaure su ga ƙwayoyin plasma ba.
Yana tarawa a cikin kodan, hanta da gyada mai. Rashin rabin rabin metformin zai dauki tsawon awa 2 zuwa 6. An cire maganin a fitsari a cikin sigar da ba ta canzawa. Ara yawan abubuwan da ke aiki zai iya faruwa tare da matsaloli tare da kodan.
Alamu don amfani
An wajabta maganin ga marasa lafiya da nau'in ciwon sukari na 2 na sukari, musamman tare da nauyi mai yawa, lokacin da abincin da aikin jiki basu da tasiri. Don lura da marasa lafiya na manya, ana iya amfani dashi azaman monotherapy ko a hade tare da insulin ko wasu wakilai na hypoglycemic.
Ga yara bayan shekaru 10, ana iya amfani da miyagun ƙwayoyi shi kaɗai ko a hade tare da insulin. Bugu da ƙari, ana amfani da allunan don hana cutar a gaban ciwon suga da sauran abubuwan haɗari don haɓaka ciwon sukari na 2, lokacin da ba za a iya samun ingantaccen iko da matakan glucose tare da canjin yanayin ba.
An wajabta maganin ga marasa lafiya da nau'in ciwon sukari na 2 na sukari, musamman tare da nauyi mai yawa, lokacin da abincin da aikin jiki basu da tasiri.
Contraindications
Wajibi ne a ƙi jiyya idan:
- rashin hankali ga abubuwan da aka gyara;
- mai ciwon sukari mai ciwon sukari;
- precoma na sukari ko coma;
- koda ko gazawar hanta;
- rashin ruwa a jiki;
- mummunan cututtukan cututtuka;
- cututtuka a cikin m ko na kullum tsari, haifar da hypoxia nama.
Tare da kulawa
Suna ɗaukar magani a hankali don gudanar da aikin tiyata mai yawa da raunin da ya faru lokacin da ya zama dole a ɗauki insulin, ciki, giya mai saurin kamuwa da guba ko ƙwaya, da rage cin abinci mai ƙarancin kuzari, lactic acidosis, da kuma kafin ko bayan radioisotope ko gwajin x-ray, a yayin da ake sarrafa waken aidin wanda yake dauke da sigar mai haƙuri ga mai haƙuri .
Yayin cikin ciki, ya kamata a dauki Merifatin tare da kulawa sosai.
Yadda ake ɗaukar Merifatin?
An yi nufin samfurin don amfani da baka. Sigar farko a lokacin monotherapy a cikin marasa lafiya shine 500 mg sau 1-3 a rana. Za'a iya canza kashi zuwa 850 MG 1-2 sau a rana. Idan akwai buƙata, to, adadin ƙwayar ya karu zuwa 3000 MG don kwanaki 7.
Yara an haife shekaru 10 ana basu damar shan 500 MG ko 850 MG sau daya a rana ko 500 MG 2 sau a rana. Za'a iya ƙara yawan sashi a cikin mako guda zuwa 2 g kowace rana don allurai 2-3. Bayan kwanaki 14, likita ya daidaita yawan magunguna, la'akari da matakin sukari na jini.
Idan aka haɗu da insulin, kashi na Merifatin shine 500-850 MG sau 2-3 a rana.
Tare da ciwon sukari
A gaban ciwon sukari, ana daukar metformin bisa ga tsarin da likita yayi, la'akari da halayen mutum na mai haƙuri da kuma sakamakon cikakken bincike.
Sakamakon sakamako na Merifatin
A wasu halayen, bayyanar mara kyau an bayyana. Gudanar da allunan idan akwai sakamako masu illa kuma an dakatar da likita.
Gastrointestinal fili
Daga bangaren narkewa, ana tashin zuciya, amai, gudawa, ciwon ciki da rashin ci. Alamar mara kyau tana faruwa a matakin farko na magani kuma tafi gaba. Domin kada ya yi karo da su, ya zama dole a fara da ƙaramar ƙwaƙwalwa kuma sannu a hankali ƙara shi.
Hematopoietic gabobin
A cikin mafi yawan lokuta, akwai take hakkin sha na bitamin B12.
Daga gefen metabolism
Wani lokacin magani yana haifar da haɓakar lactic acidosis.
Cutar Al'aura
Halin rashin lafiyan yana faruwa a cikin yanayin itching, fitsari da erythema.
Tasiri kan ikon sarrafa abubuwan inji
Tare da monotherapy, ƙwayar ba ta da mummunar tasiri a kan sarrafa sufuri da kuma aiwatar da ayyukan da ke buƙatar karuwar hankali da kuma hanzarta halayen psychomotor. Duk da wannan, mai haƙuri ya kamata ya lura da alamun hypoglycemia kuma yayi hankali.
Umarni na musamman
Yayin aikin jiyya, wajibi ne don saka idanu kan matakin glucose a cikin jini.
Yayin aikin jiyya, wajibi ne don saka idanu kan matakin glucose a cikin jini.
Yi amfani da tsufa
A cikin marasa lafiya bayan shekaru 60, akwai haɗarin samuwar lactic acidosis, don haka bai kamata a sha miyagun ƙwayoyi a cikin wannan rukuni na marasa lafiya ba.
Aiki yara
Ba a ba da magani ga yara 'yan ƙasa da shekara 10 ba.
Yi amfani da lokacin daukar ciki da lactation
Ba'a ba da shawarar shan Allunan ba yayin ɗaukar jariri da shayarwa, tun da abu mai aiki ya ratsa ta cikin ƙwayar cuta da cikin madara. Ana iya ba da maganin ta warke idan amfanin magani ya wuce haɗarin rikitarwa a cikin yaro.
Aikace-aikacen aiki mara kyau
An hana yin amfani da miyagun ƙwayoyi idan anyi rashin lafiyar jiki.
Amfani don aikin hanta mai rauni
An ba da izinin aiwatar da jiyya tare da Merifatin idan akwai aiki na hanta mai rauni.
An ba da izinin aiwatar da jiyya tare da Merifatin idan akwai aiki na hanta mai rauni.
Yawan abincinta na Merifatin
Idan kayi amfani da adadin da aka ba da shawarar magani, ƙwayar cutar za ta iya faruwa, ya bayyana a cikin hanyar lactic acidosis. Sun daina shan maganin kuma suna buƙatar ƙwararrun masani waɗanda ke ba da izinin bayyanar cututtukan alamomin cuta da jijiyoyin zuciya.
Yin hulɗa tare da wasu kwayoyi
An hana shi haɗuwa da metformin tare da magungunan radiopaque-iodine. Tare da taka tsantsan, suna ɗaukar Merifatin tare da Danazole, Chlorpromazine, glucocorticosteroids, diuretics, intiable beta2-adrenergic agonists da antihypertensive, banda masu hana masu agiotensin canza enzyme.
An lura da karuwa a cikin taro na metformin a cikin jini a lokacin hulɗa tare da magungunan cationic, daga cikinsu amiloride. Absorarin ƙwayar metformin yana faruwa lokacin da aka haɗu da nifedipine. Maganin hana haihuwa na ciki yana rage tasirin maganin cutar.
Amfani da barasa
A lokacin jiyya, an haramta shan giya da samfuran da ke ƙunshe da ethanol, saboda haɗarin haɗari na lactic acidosis.
Analogs
Idan ya cancanta, yi amfani da irin wannan kwayoyi:
- Bagomet;
- Glycon;
- Glucophage;
- Langerine;
- Siafor;
- Kayan tsari.
Kwararrun sun zaɓi analog, yin la'akari da tsananin cutar.
Magunguna kan bar sharuɗan
Don sayan magani a kantin magani, kuna buƙatar takardar sayan magani.
Zan iya saya ba tare da takardar sayan magani ba?
Ba za a iya siye magungunan ba tare da takardar sayan magani daga likita ba.
Farashi don Merifatin
Kudin maganin yana dogara da manufofin farashi na kantin magani kuma aƙalla 169 rubles.
Yanayin ajiya na miyagun ƙwayoyi
An sanya kunshin tare da allunan a cikin duhu, bushe da rashin isa wurin yara tare da zazzabi wanda bai wuce + 25 ° C ba.
Ranar karewa
Magungunan yana riƙe da kaddarorinsa na tsawon shekaru 3 daga ranar da aka ƙera shi, ƙarƙashin dokokin ajiya. Bayan ranar karewa, an zubar da maganin.
Mai masana'anta
Pharmasintez-Tyumen LLC tana cikin ayyukan samar da magunguna a Rasha.
Yayin magani, haramun ne a sha giya.
Nazarin Merifatin
Konstantin, ɗan shekara 31, Irkutsk: "Ina amfani da miyagun ƙwayoyi koyaushe. Babu wasu sakamako masu illa. Sakamakon farashi. Ina bayar da shawarar."
Lilia, 'yar shekara 43, Moscow: "A farkon zamanin magani na Merifatin, tashin zuciya da farin ciki sun tashi. Na tafi wurin likita. Ya canza sashi. Ya ji sauki."
