Ibertan yana cikin rukunin magungunan antihypertensive. Magungunan ba su da ƙananan contraindications, wanda ke faɗaɗa ɗaukacin aikace-aikacensa. Hadarin sakamako masu illa a yayin jiyya yana da ƙasa. Amfanin magani shine ikon kiyaye sakamakon da aka samu yayin maganin na kwana 1 bayan shan kwayoyin.
Sunan kasa da kasa mai zaman kansa
Irbesartan
Sunan duniya mai zaman kanta na Ibertan shine Irbesartan.
ATX
C09CA04
Saki siffofin da abun da ke ciki
Zaku iya siyan wakili na rigakafi a cikin allunan da aka sanya fim. Ayyukan mai aiki shine irbesartan. Kayan aiki shine kayan haɗin jiki, wanda ke nufin cewa sauran mahadi a cikin abun da ke ciki bai nuna ayyukan antihypertensive ba. Hankalin irbesartan a cikin kwamfutar hannu 1: 75, 150 da 300 MG. Zaka iya siyan samfurin a cikin blisters (pcs 14). Akwatin kwali na dauke da fakiti guda 2.
Aikin magunguna
Magungunan yana ba da sakamako mai illa. Babban abu a cikin abun da yake ciki yana aiki azaman mai adawa da karɓa. Wannan yana nufin cewa irbesartan ya rikitarwa tare da aikin masu karɓar angiotensin II, wanda ke taimakawa wajen kula da ganuwar jijiyoyin jiki a cikin sautin (rage sharewar jijiyoyin, jijiya). A sakamakon haka, yawan hauhawar jini ya ragu kadan.
Aikin nau'in angiotensin nau'in 2 ba kawai kekantar da jijiyoyin jini ba tare da ƙaruwa mai zuwa ba, amma har da ƙa'idar tarawar platelet da mannewar su. Haɗin ma'amala da masu karɓa da wannan hormone yana hana samar da sinadarin nitric oxide, wanda shine tushen vasorelaxating. Karkashin tasirin Ibertan, hanyoyin da aka bayyana suna raguwa.
Bugu da ƙari, akwai raguwa a cikin taro na aldosterone. Wannan hormone ne na rukunin mineralocorticoid. An samar dashi ta hanyar adrenal bawo. Babban aikinta shine daidaita jigilar sodium da potassium cations da chlorine anions. Wannan hormone yana tallafawa irin wannan mallakar kyallen takarda kamar hydrophilicity. Aldosterone yana haɗuwa tare da halartar nau'in angiotensin nau'in 2. Don haka, tare da raguwa a cikin ayyukan ƙarshen, an dakatar da aikin farkon kwayoyin.
Magungunan yana ba da sakamako mai illa.
Koyaya, babu wani mummunan tasiri game da kinase II, wanda ke da hannu a cikin lalata bradykinin kuma yana ba da gudummawa ga samuwar nau'in angiotensin nau'in 2. Irbesartan bashi da wani tasiri a cikin yawan zuciya. A sakamakon haka, haɗarin rikice-rikice daga tsarin zuciya. An lura cewa kayan aikin da ake tambaya baya tasiri wajen samar da triglycerides, cholesterol.
Pharmacokinetics
Magungunan ba ya fara aiki nan da nan. Ana iya ganin ingantattun canje-canje 3-6 bayan shan miyagun ƙwayoyi. Sakamakon wannan, babu raguwar matsi mai tsafta. Rage saukar karfin jini yana gudana lafiya. Ba a cimma sakamako mai ƙoshin lafiya nan da nan, amma bayan makonni 2 na farko bayan fara magani. Inganta ingantaccen inganci yana cikin tsawon lokaci. Ana lura da mafi kyawun sakamako tare da maganin rigakafin jini bayan watanni 1-1.5.
Bayan ɗaukar kashi ɗaya na irbesartan, mafi girman ƙwayar plasma yana isa bayan sa'o'i 2. Ingancin wannan sinadari bai wuce kashi 80% ba. Za'a iya sha magani a kowane lokaci da ya dace. Cin abinci baya rage shaye shaye kuma baya tasiri tasirin bayyanar cutar.
Tare da jiyya, irbesartan ba ya tarawa cikin tarawar jini. Wannan kayan yana canza canji tare da sakin 1 na metabolite - glucuronide. Wannan tsari yana faruwa ne sakamakon iskar shaka. Babban hanyoyin cire kayan: tare da bile, yayin urination. Game da cutar hanta da ƙodan koda, babu wani canji mai mahimmanci a cikin abubuwan da ke cikin magunguna.
An wajabta maganin don maganin nephropathy, wanda aka haɓaka da asalin nau'in ciwon sukari na 2.
Alamu don amfani
Babban jagorar yin amfani da miyagun ƙwayoyi shine hauhawar jini. Bugu da kari, za a iya amfani da miyagun ƙwayoyi a cikin irin wannan yanayin na jijiyoyin ƙwayar cuta kamar yadda nephropathy (lalacewar parenchyma na koda). Ana amfani dashi idan wannan cuta ta haɗu da tushen nau'in ciwon sukari na 2 na hawan jini ko hauhawar jini.
Contraindications
Akwai 'yan ƙuntatawa game da saduwa da miyagun ƙwayoyi a cikin tambaya: rashin haƙuri ga sashin aiki mai aiki, rashi lactase, ƙarancin shan galactose, glucose.
Tare da kulawa
Yawancin dangi na contraindications an lura dasu, wanda ya wajaba don nuna karuwar hankali, gami da:
- take hakkin sufuri na sodium cations;
- abinci mai gishiri-gishiri;
- lalataccen aikin na koda, musamman, takaitawar lumen na artery koda;
- hanzarta kawar da ruwa daga jiki, gami da cututtukan cututtukan cuta, tare da amai, gudawa;
- amfani da kwanan nan na thiazide diuretics;
- lokacin dawo da bayan fitsarin koda;
- rage jinkirin wucewa cikin jini ta cikin mitral, aortic valves, wanda za'a iya haifar dashi ta hanyar stenosis;
- Amfani na lokaci daya tare da shirye-shirye dauke da lithium;
- cututtukan endocrine da ke da alaƙa da rashi na aldosterone;
- canje-canje atherosclerotic a cikin tasoshin cerebral;
- cututtuka na tsarin zuciya da jijiyoyin jini: ischemia, karancin aikin wannan sashin.
Tare da taka tsantsan, an wajabta magunguna don cutar da tsarin cututtukan zuciya.
Yadda ake ɗaukar Ibertan?
A matakin farko na magani, yawan irbesartan yana da karanci (150 MG). Maimaitawa da yawa - sau 1 a rana. Za'a iya sha magani a cikin komai a ciki, lokacin ko bayan abinci. Koyaya, a wasu halaye, ana buƙatar rage ƙarfin koda a cikin kashi - har zuwa 75 MG kowace rana. Alamar wannan shine bushewar ruwa, raguwar yawan jini da yake yawo, shan magungunan da ke inganta fitar ruwa, da abinci mai gishiri.
Idan jiki yayi rauni ga mafi ƙarancin amfani, to yawan ƙwayar irbesartan yana haɓaka 300 MG kowace rana. An lura cewa shan allurai fiye da 300 MG ba ya kara tasirin magungunan ƙwayar cuta. Lokacin canza adadin miyagun ƙwayoyi a cikin babban shugabanci, ya kamata a kiyaye hutu (har zuwa makonni 2).
Jiyya na nephropathy: an wajabta magunguna 150 MG kowace rana. Idan ya cancanta, ana ƙaruwa da kashi na abu mai aiki zuwa 300 MG (ba fiye da lokaci 1 kowace rana ba).
Tare da ciwon sukari
An yarda da miyagun ƙwayoyi don amfani. Ya kamata hanyar fara magani ya fara da mafi ƙarancin (150 MG). Idan an yarda da miyagun ƙwayoyi, adadin sinadaran da ke aiki na iya ƙara ƙaruwa.
An ƙayyade tsawon lokacin jiyya daban daban.
Sakamakon sakamako na Ibertan
Yayin lura, an lura da yawan rikice-rikice na asibiti, yawan faruwar abin da ya dogara da yanayin mai haƙuri, kasancewar wasu cututtuka.
A wani bangare na bangaren hangen nesa
Ba a lura.
Daga tsoka da kashin haɗin kai
Jin zafi a kirji, tsokoki, da kasusuwa.
Gastrointestinal fili
Ciwon, tashin zuciya, sako-sako da bakin ciki, ƙwannafi, zafin zuciya.
Hematopoietic gabobin
Increaseara yawan abubuwan halittar phoinhokinase, potassium, da raguwar haemoglobin.
Tsarin juyayi na tsakiya
Dizziness, ciwon kai, raunin tunani, tare da ƙarin yawan gajiya, damuwa, damuwa.
Daga tsarin urinary
Rashin aikin koda.
Daga tsarin numfashi
Zazzabin bushe yana bayyana.
Yayin shan magani, bushewa na iya farawa.
Daga tsarin kare jini
Rashin Jima'i.
Daga tsarin zuciya
Canza shi a cikin bugun zuciya, abin sha'awa na fitar da fata zuwa fuskar fata.
Cutar Al'aura
Urticaria, vasculitis.
Tasiri kan ikon sarrafa abubuwan inji
Saboda haɗarin haɗarin sakamako masu illa daga tsarin juyayi na tsakiya, dole ne a yi taka tsantsan lokacin tuki motocin. Ba a gudanar da binciken lafiya game da wannan magani yayin ayyukan da ke buƙatar kulawa ba.
Umarni na musamman
A yayin warkarwa daga asalin rashin ruwa, an lura da rashin daidaituwa game da ma'aunin ruwan-lantarki. A wannan yanayin, ɗaukar Ibertan na iya haifar da ƙara raguwa a cikin matsin lamba.
Game da rashin isasshen aiki na renal, ana bada shawara don sarrafa abun ciki na potassium, creatinine.
A waje ɗaya daga cikin ƙwayar jijiya ɗan adam, matsanancin nau'in tashin hankali yana tasowa.
Game da rashin isasshen aiki na renal, ana bada shawara don sarrafa abun ciki na potassium, creatinine.
An lura da ƙarancin ingancin Ibertan a cikin lura da marasa lafiya da ke dauke da cutar hyperaldosteronism na farko.
Idan akwai hali zuwa rikice-rikice daga tsarin zuciya, kana buƙatar kulawa da kullun matakin hawan jini yayin jiyya, saboda wannan yana ƙara haɗarin infarction na zuciya.
Yi amfani da tsufa
An ba da shawarar marasa lafiya masu shekaru 75 da haihuwa su sha maganin a cikin adadi kaɗan - 75 MG kowace rana.
Aiki yara
Ba a amfani dashi.
Yi amfani da lokacin daukar ciki da lactation
Ba da shawarar ba.
Aikace-aikacen aiki mara kyau
Rashin gajiya ba dalili bane don katse jiyya. Yayin shan magani akan asalin wannan yanayin cutar, yakamata ayi taka tsantsan.
Haɓaka cututtukan hanta mai laushi ba dalili ba ne don karɓar ƙwayoyi.
Amfani don aikin hanta mai rauni
Haɓaka ƙwayoyin cuta mai sauƙi na wannan ƙwayar cuta ba dalili bane don karɓar ƙwayoyi. Ba'a bincika amincin shan miyagun ƙwayoyi a kan asalin lalacewar hanta mai yawa ba. Don haka, zai fi kyau mu guji magani tare da ƙwayar tambaya a cikin wannan yanayin cutar.
Ibertan overdose
Mafi sau da yawa, marasa lafiya suna rage karfin jini, ƙasa da ci gaban tachycardia. A cikin lokuta daban, alamun bradycardia yana faruwa. Rage girman bayyanar mara kyau zai taimaka wajan fitar da ciki, alƙawarin sihirin (muddin an sha magani). Don kawar da alamun mutum, an tsara magunguna na musamman, alal misali, don tsara yanayin tsinkayewar zuciya, matakin matsa lamba.
Yin hulɗa tare da wasu kwayoyi
Hydrochlorothiazide bai ba da gudummawa ga canji a cikin harhada magunguna da magungunan likitan Ibertan ba. Ana lura da irin wannan sakamakon tare da hulɗa da miyagun ƙwayoyi a cikin tambaya da Warfarin.
Abubuwan haɗin gwiwa
Tare da Ibertan, sauran magungunan da ke taimakawa rage matsin lamba ba a tsara su ba.
Karku yi amfani da shirye-shirye waɗanda ke ɗauke da lithium. A wannan yanayin, yawan guba na miyagun ƙwayoyi da ake tambaya yana ƙaruwa.
Hydrochlorothiazide tare da Ibertan ba shi da kyau a hade tare da colestiramine.
Ba da shawarar haɗuwa ba
NSAIDs suna haifar da haɓaka gazawar koda, hyperkalemia.
Hydrochlorothiazide tare da Ibertan ba shi da kyau a hade tare da colestiramine.
Fluconazole yana hana tsarin canji na maganin da ake tambaya.
Haɗuwa yana buƙatar taka tsantsan
An ba shi izinin yin amfani da beta-blockers, diuretics na ƙungiyar thiazide, allunan tashar alli tare da Ibertan.
Yakamata a yi taka tsantsan yayin amfani da miyagun ƙwayoyi a cikin tambaya da magunguna dauke da potassium.
Amfani da barasa
Ganin cewa ethanol yana ba da gudummawa ga haɓaka tasoshin jini, ba a ba da shawarar yin amfani da abin sha mai giya a lokacin jiyya tare da Ibertan. A wannan yanayin, aikin antihypertensive na miyagun ƙwayoyi yana ƙaruwa.
Ganin cewa ethanol yana ba da gudummawa ga haɓaka tasoshin jini, ba a ba da shawarar yin amfani da abin sha mai giya a lokacin jiyya tare da Ibertan.
Analogs
Zaɓuɓɓuka masu inganci don maye gurbin miyagun ƙwayoyi da ake tambaya:
- Irbesartan
- Irsar;
- Aprovel;
- Telmisartan.
Zaɓin farko shine madadin kai tsaye ga Iberta. Wannan kayan aiki ya ƙunshi kayan aiki guda ɗaya. Yawan sashi shine 150 da 300 MG a cikin kwamfutar hannu 1. Dangane da mahimman sigogi, Irbesartan bai bambanta da Ibertan ba.
Irsar wani kwatancen magani ne wanda ake tambaya. Ba ya bambanta a cikin kayan haɗin, sashi na abu mai aiki, alamomi da contraindications. Wadannan kudaden suna cikin nau'in farashin guda ɗaya. Wani madadin (Aprovel) farashin ƙarin (600-800 rubles). Fitar saki - Allunan. A cikin 1 pc ya ƙunshi 150 da 300 mg na irbesartan. Dangane da haka, za a iya kuma tsara maganin ta maimakon maganin da ake tambaya.
Telmisartan ya ƙunshi ƙunshiyar suna. Adadinsa shine 40 da 80 MG a kwamfutar hannu 1. Principlea'idar aikin miyagun ƙwayoyi ta dogara ne tare da toshe ayyukan masu karɓar mahaɗan da ke hulɗa tare da angiotensin II. A sakamakon haka, an lura da raguwar matsin lamba. Don haka, bisa ga tsarin aikin, Telmisartan da miyagun ƙwayoyi da ake tambaya sun yi kama. Alamu don amfani: hauhawar jini, rigakafin haɓaka rikice-rikice (gami da mutuwa) a cikin cututtuka na tsarin zuciya.
Telmisartan yana da ƙarin ƙarin contraindications. Haramcin amfani da miyagun ƙwayoyi yayin daukar ciki, lactation, a cikin ƙuruciya, tare da cin zarafin ƙwayar biliary, an lura da hanta. Ba'a ba da shawarar a haɗa shi da kwayoyi daga ƙungiyar angiotensin-juyawa masu hana enzyme ba. Daga cikin kudaden da aka yi la'akari da su, Telmisartan shine kawai madadin da za a iya amfani da shi maimakon Ibertan, idan har ya kasance mai haɓaka ga abubuwan da ke aiki, irbesartan, yana haɓaka.
Magunguna kan bar sharuɗan
Magunguna magani ne.
Zan iya saya ba tare da takardar sayan magani ba?
A'a, kuna buƙatar samun takardar sayan likita don sayan maganin.
Farashi don Ibertan
Matsakaicin matsakaici shine 350 rubles.
Yanayin ajiya na miyagun ƙwayoyi
Nagari zafin jiki na yanayi - ba ya wuce + 25 ° С.
Ranar karewa
Magungunan da ake tambaya na riƙe da kayanta na tsawon watanni 36 daga ranar da aka sake su.
Mai masana'anta
Polpharma (Poland).
Magunguna magani ne.
Nazarin Ibertan
Daria, dan shekara 45, Saratov
Anyi mana maganin hauhawar jini tsawon lokaci. Tun daga wannan lokacin nake neman magani wanda ba zai taɓa yin tashin hankali ba kuma yana samar da sakamako mai kyau na warkewa. Na gwada abinci daban-daban na kayan abinci da na kantin magani. Ina son tasirin cutar Ibertan. Duk da yake na karba, na ji dadi.
Veronika, 39 years old, Krasnodar
Ta fara karatun magani ne a kan asalin abincin da ake amfani da shi na hypochloride. Don wannan dalili, likita bai ba da shawarar ɗaukar madaidaicin kashi ba, amma an ba da 75 MG kowace rana. Ban ga sakamako da yawa ba. Lokacin da likita ya ba da izinin ƙara adadin ƙwayar ta hanyar sau 2, matsin lamba ya ragu sosai, ya koma al'ada. Kafin wannan, akwai kullun tsalle-tsalle a cikin karfin jini, da sama.
