Magunguna waɗanda ke sarrafa danko na jini sun kasu kashi biyu: magungunan anticoagulants (waɗanda suke tunanin jini) da kuma wakilan antiplatelet (wakilan da ke hana haɗarin platelet). Thrombo ACC yana cikin rukunin rukunin magunguna na ƙarshe kuma an yi niyya don kula da marasa lafiya waɗanda ke fama da matsanancin ƙwayar mai mai narkewa, ciwon sukari mellitus ko hawan jini.
Sunan kasa da kasa
Acetylsalicylic acid. A cikin Latin - Acidum acetylsalicylicum.
Thrombo ACC an yi shi ne don maganin marasa lafiya da ke fama da matsanancin narkewar mai, ciwon sukari mellitus ko hawan jini.
ATX
B01AC06
Saki siffofin da abun da ke ciki
Ana amfani da miyagun ƙwayoyi a cikin nau'i na farin biconvex farin Allunan mai rufi tare da fim mai rufi. Naúrar miyagun ƙwayoyi ya ƙunshi 50 ko 100 MG na abu mai aiki - acetylsalicylic acid. Kamar yadda aka gyara kayan sune:
- sukari madara;
- microcrystalline cellulose;
- colloidal silicon dioxide;
- dankalin turawa, sitaci.
Takaddun kayan shiga shine ya hada da talc, ethyl acrylate copolymer, triacetin da acid methaclates. Allunan ana samunsu cikin fakiti mai laushi kamar guda 14 ko 20. A cikin kwali na kwali na raka'a 14 na miyagun ƙwayoyi ya ƙunshi blisters 2, don raka'a 20 - 5 blisters.
Ana samun magungunan a cikin nau'ikan allunan biconvex zagaye na farin launi.
Aikin magunguna
Acetylsalicylic acid (ASA) yana da mallakin antiplatelet wanda ke hana haɗarin platelet na jini. Kwayar aiki mai aiki tana cikin rukunin magungunan anti-steroidal anti-inflammatory (NSAIDs), kasancewar asalin acid ɗin na salicylic acid. Tasirin warkewa yana dogara ne akan abin da ba'a iya magancewa na cyclooxygenase. Lokacin da aka hana enzyme, samar da aikin prostaglandins, thromboxane da prostacyclins suna rushewa. Sakamakon murkushewar ɓarwar thromboxane A2, samuwar platelet, haɗuwa (clumping) da platelet sedimentation.
Tasirin antiplatelet ya ci gaba har sati daya bayan amfani guda. Ana amfani da irin wannan tasirin tasirin acetylsalicylic acid don magani da kuma rigakafin ischemic, cututtukan varicose, infarction na myocardial.
Pharmacokinetics
Lokacin da aka sarrafa shi a baki, acetylsalicylic acid yana cikin 100% a cikin hancin hanji. Allunan ba su lalata mucosa na ciki saboda kasancewar fim membrane. A lokacin ɗaukar ruwa, ɓangaren ƙarfe metabolization zuwa salicylic acid yana faruwa. Ana canza wannan sinadaran a cikin hanta don samar da salicylates.
Lokacin da ya shiga cikin jini, ASA yana ɗaure zuwa 66-98% tare da ƙwayoyin plasma kuma ana rarraba shi da sauri zuwa kyallen takarda. Magani tara ba ya faruwa. Maƙƙarfan rabin rai ya kai minti 15-20. Tsarin urinary ya wuce kashi 1% na maganin da aka karba a ainihin tsarin sa. Sauran suna barin jiki a cikin hanyar metabolites. Tare da aiki na al'ada na nephrons, 80-100% na miyagun ƙwayoyi an keɓe ta cikin kodan har tsawon kwanaki 1-3.
Lokacin da aka sarrafa shi a baki, acetylsalicylic acid yana cikin 100% a cikin hancin hanji.
Alamu don amfani
Magungunan an yi niyya don hana mummunan ciwon zuciya na ƙwayar zuciya yayin da mai haƙuri ya kasance cikin haɗari (hawan jini, kiba, shekarun da suka wuce shekaru 50, halaye marasa kyau, ciwon sukari). A cikin zuciya, kwararrun likitocin suna da hakkin rubanya amfani da miyagun ƙwayoyi a waɗannan halaye masu zuwa:
- a matsayin gwargwado na rigakafin thromboembolism bayan abubuwan tallafi na wulakanci da aikin tiyata a kan tasoshin: jijiyoyin zuciya da ke kewaye, tiyata, angioplasty
- tare da zurfin jijiya thrombosis;
- domin taimako na zazzabi don zazzabi saboda mura;
- hana yaduwar jini a cikin kwakwalwa;
- don lura da angina barga da kuma nau'in da ba a yarda da shi ba;
- don hana ci gaba da maimaita bugun zuciya;
- a matsayin rigakafin bugun jini, gami da yanayi tare da hadarin cerebrovascular.
Ana amfani da miyagun ƙwayoyi don hana embolism na huhu bayan tsawaita bugun jini, wanda aka buƙata a cikin bayan aikin.
Contraindications
Ba a bada shawarar magani ba ko kuma an haramta yin amfani dashi a cikin halayen masu zuwa:
- susara yawan yiwuwar kyallen takarda zuwa acetylsalicylic acid da sauran NSAIDs;
- narkewar jini;
- rashin haƙuri a cikin lactase, malabsorption na monosaccharides;
- rauni na huji na ciki na gastrointestinal fili;
- basur na jini;
- haɗuwa tare da sashi na methotrexate na 15 MG tare da amfani guda ɗaya a mako;
- mai tsanani game da koda ko hepatic kasawa;
Ba a bada shawarar yin amfani da kayan aikin don amfani da marasa lafiya da raunin zuciya III da aji na III ba.
Tare da kulawa
Ana buƙatar yin taka tsantsan yayin da ake amfani da maganin ƙwaƙwalwar ƙwayoyi don marasa lafiya da ke fama da cututtukan da ke biye da yanayin, da yanayin:
- asma;
- gout
- raunuka na ciki da duodenum;
- cututtuka na numfashi na kullum;
- keɓantar da ƙododin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwa ƙasa da 30 ml / min;
- Kwana uku na ciki;
- dysfunction hanta;
- esophagus reflux esophagitis;
- hay zazzabi;
- haɗu da amfani da maganin murɗaɗɗun magunguna, magungunan kashe kumburi, magungunan rheumatic.
An ba da shawarar yin shawara tare da likitan ku game da soke maganin ƙwayar cuta kafin shirin tiyata na tiyata.
Yadda ake ɗauka
Allunan an yi su ne don maganin baka. Ana nuna tasirin warkewar ne kawai yayin tsawan raunin jiyya. Ma'aunin kwararrun likitanci ne kawai yake iya tantancewa da tsawon lokacin jiyya, wanda ya dogara da halaye na mutum na haƙuri (shekaru, nauyin jiki), gwaje-gwaje na dakin gwaje-gwaje da kuma nazarin jiki. Matsayin tsananin da nau'in cuta yana shafar tsarin kulawa.
| Yin rigakafi da magani | Tsarin warkewa (sashi na yau da kullun), mg / rana |
| Babban myocardial infarction | 50-100 |
| Secondary muscle muscle infarction, angina pectoris | |
| Bugun jini, hatsarin cerebrovascular | |
| Zurfafa jijiya jini, hanawa daga cikin ƙwayoyin huhun jini | 100-200 (Allunan guda 2 sau daya) |
Da safe ko yamma
Lokacin zartar da amfani guda ɗaya a rana, ana bada shawara don shan miyagun ƙwayoyi da dare kafin lokacin kwanciya. Lokacin amfani da allunan 2 ko fiye, yana da mahimmanci don tsayar da tazara tsakanin allurai na sa'o'i 12. A wannan yanayin, mutum yana shan magani da safe da maraice.
Kafin ko bayan abinci
An ba da shawarar a sha magani kafin abinci don a hana pepat daga hanji ciki. A wannan yanayin, wajibi ne a sha Allunan tare da adadin mai yawa.
Shan maganin don ciwon sukari
Ana ajiye cholesterol a cikin nau'ikan kyawawan filaye a jikin bangon jijiyoyin jiki. Sabili da haka, masu ciwon sukari suna cikin haɗari - don mutanen da ke da haɗari ga cututtukan cututtukan zuciya (kiba, shan taba, tsufa, hauhawar jini). Tare da ciwon sukari, ana rubanya 100 MG kowace rana.
Tare da ciwon sukari, ana rubanya 100 MG kowace rana.
Har yaushe za a ɗauka
Ana ba da haƙuri ga masu fama da rikice-rikice na tsarin zuciya da jijiyoyin jini don ɗaukar wakilin antiplatelet a duk rayuwa. A miyagun ƙwayoyi zai taimaka rage hadarin ƙwanƙwasa jini a cikin ɗakunan zuciya. Wannan rukunin mutanen sun hada da mutanen da ke fama da cututtukan zuciya da jijiyoyin jini, ciwon mara na firamillation, angina pectoris, gazawar zuciya.
Marasa lafiya tare da jijiyoyin varicose, masu saurin kamuwa da jini, ɗaukar magani a cikin makonni 1-2 har sai ƙaramar plate ɗin ta ɓace gaba ɗaya.
Side effects
Idan mummunan tasirin ya faru, tuntuɓi likitan ku wanda zai maye gurbin ƙwayoyi ko daidaita sashi na yau da kullun.
Gastrointestinal fili
Daga tsarin narkewa, bayyanar tashin zuciya da amai. A lokuta da dama, shan magunguna yakan haifar da cututtukan ciki da na ciki, tare da zubar jini. Rikici a cikin hanta saboda karuwar ayyukan aminotransferases a hepatocytes an yi rikodin.
Hematopoietic gabobin
Ana ganin alamun bayyanannan masu zuwa:
- basur;
- zub da jini a cikin fitsarin urinary;
- zub da jini;
- hawan jini;
- epistaxis, zubar jini bayan jini.
Hidden basur yana tare da cyanosis da asthenia.
Tsarin juyayi na tsakiya
Rashin damuwa daga tsarin juyayi (tinnitus, dizziness, ciwon kai, rage ƙarancin gani da ji) na iya kasancewa alamu na yawan yawan damuwa.
Cutar Al'aura
Tare da ƙara ji da hankali ga abubuwan da ke cikin miyagun ƙwayoyi, fitsari, itching, erythema, Quincke's edema, tashin hankali anaphylactic, rhinitis, bronchospasm, kumburi da hancin mucosa da pharynx na iya haɓaka.
Don ƙonewar rashin lafiyar, dole ne a kira ƙungiyar motar asibiti.
Umarni na musamman
Abubuwan da ke aiki a cikin ƙananan allurai na iya tayar da tashin hankali ko ɓacin rai a gaban haɗarin da ya dace, yayin da za a iya fitar da wani babban sakamako mai tasirin cutar haɓaka. Dole ne a ɗauka abin da ya gabata na tunawa ta hanyar marasa lafiya da ke fama da ciwon sukari.
Aiki mai aiki cikin ƙananan allurai na iya tsokanar da farkonsa ko kuma ƙaruwa da gout.
Acetylsalicylates suna da sakamako mai tsawo wanda yakanyi kwanaki 6-7 bayan gudanarwa, wanda ke kara haɗarin zubar jini yayin tiyata. Don rigakafin, an soke maganin a mako guda kafin tiyata.
Amfani da barasa
Ethanol da ke cikin barasa yana haifar da yiwuwar lalacewar cututtukan mahaifa ga lalata narkewa.
Tasiri kan ikon sarrafa abubuwan inji
A lokacin da ake shan magani, ana bada shawara a guji tuki, yin ma'amala tare da hadaddun hanyoyin, da sauran ayyukan da ke buƙatar natsuwa da saurin aiki.
Yi amfani da lokacin daukar ciki da lactation
Kayan aiki yana shiga cikin shinge ta mahaifa, wanda shine dalilin da yasa a farkon farkon farkon fitowar mahaifar zai iya katse labulen manyan gabobin jiki da tsarin. Lokacin haihuwa, jariri na iya samun lahani na zuciya ko maƙil.
A cikin watanni uku na uku, maganin yana fara rage lokacin haihuwa kuma zai iya haifar da jijiyar jijiyoyin jiki a cikin amfrayo. Saboda haka, ana amfani da wakilin antiplatelet ne kawai a lokuta na gaggawa lokacin da hatsarin rayuwar mahaifiyar ya wuce hadarin cututtukan ƙwayoyin cuta a cikin tayin.
A cikin tsaka-tsaka na tsakiya, ana ba da izinin amfani da miyagun ƙwayoyi tare da sashi wanda ba ya wuce 150 MG kowace rana. Tare da tsawan magani, ana bada shawarar soke shayarwa.
A cikin tsofaffi marasa lafiya da suka girmi shekaru 50, akwai haɗarin yawan zubar jini.
Maganar thrombo ACC ga yara
A cikin ƙuruciya, haramun ne a yi amfani da har zuwa shekaru 18. Banbancen shine rickets da cutar Kawasaki.
Yi amfani da tsufa
A cikin tsofaffi marasa lafiya da suka girmi shekaru 50, akwai haɗarin yawan zubar jini.
Yawan damuwa
Tare da zagi da miyagun ƙwayoyi, yana yiwuwa haɓaka hoton asibiti na yawan abin sha da yawa wanda yake daidai da alamun bayyanar maye mai guba:
- ciwon kai da farin ciki;
- ringi a cikin kunnuwa;
- rikicewa da asarar hankali;
- karuwar gumi;
- karuwar numfashi saboda hauhawar jini, huhun ciki;
- arrhythmia, hypotension, bugun zuciya;
- take hakkin metabolism na ruwa-gishiri;
- na ciki;
- amai, coma;
- coma, tsoka cramps.
Game da yawan abin sama da ya kamata, asibiti cikin gaggawa tare da raunin ciki da adsorbent ya zama dole. Magunguna yana da niyyar riƙe mahimman ayyuka da tallafawa ginin acid, ma'aunin ruwa-electrolyte. Lokacin da yanayin ya zama al'ada, ana yin maganin cututtukan alamu.
Game da yawan abin sama da ya kamata, asibiti cikin gaggawa tare da raunin hanji ya zama dole.
Yin hulɗa tare da wasu kwayoyi
Ta amfani da acetylsalicylic acid a lokaci guda tare da wasu magunguna, halayen da ke gaba suna yiwuwa:
- Rage yawan ƙwayar plasma na methotrexate saboda ƙaurawar ƙarshen daga masu kariyar.
- Yiwuwar zubar jini yana ƙaruwa, ƙwaƙwalwar ƙwayar cuta (ƙara yawan tasirin maganin duka magunguna) an lura lokacin da aka haɗu da magungunan anticoagulants, clopidogrel, thrombolytic jamiái.
- Za a iya samun yawan abin sama da ya kamata yayin jiyya tare da Digoxin.
- Ana amfani da sinadarin acid din naproproic saboda lalacewarsa daga sunadarai.
- Ibuprofen yana raunana maganin warkewar ƙwayar, saboda ita ce maganin ƙetaren magunguna.
A hade tare da glucocorticosteroids, ana yin karuwa a cikin excretion na salicylates da raunin sakamako na antiplatelet.
Analogs
Idan ya zama dole a daina maganin, likitan na da 'yancin rubuta wata hanyar magani tare da daya daga cikin wadanda zasu maye gurbin, kamar:
- Cardiomagnyl;
- Sake karantawa
- Aspenorm;
- Thrombogard;
- Godasal;
- Detralex
Aspirin Cardio, wanda aka mamaye shi cikin jiki gabaɗaya, ana nufin analogues a cikin fili mai aiki.
Magunguna kan bar sharuɗan
Ana sayar da maganin a cikin magunguna ba tare da takardar sayan magani ba.
Farashi don Thrombo ACC
Matsakaicin farashin magani yana bambanta daga 37 zuwa 160 rubles, dangane da adadin allunan a cikin kwali.
Yanayin ajiya na miyagun ƙwayoyi Thrombo ACC
An buƙaci adana fakitin a bushe, iyakance daga wurin haske a yanayin zafi har zuwa +25 ° C. Kada kabar magani ya fada hannun yara.
Ranar karewa
Shekaru 3
Nazarin likitoci da marasa lafiya game da Thrombo ACC
Evgeny Filippov, likitan zuciya, Rostov-on-Don
Na rubuto TromboAss ne kawai bayan na bincika mai haƙuri game da yanayin aikin jijiyoyin jini. Tasirin magungunan ya tabbatar da kansa a cikin gwaji na asibiti. A aikace na, na lura da ci gaba a cikin kyautatawar marasa lafiya bayan makonni 1-2 na warkewa. Ba na ba da shawarar rubuta magani ga kanku.
Valery Krasnov, ɗan shekara 56, Ryazan
Na kwashe TromboAss na tsawon shekaru 5, saboda likitan likitan ya yi wasiyya saboda cututtukan jijiyoyin bugun gini. Kafin ɗaukar allunan, an yi aikin tiyatar jini sau da yawa. Bayan thinning jini, yanayin ya inganta kuma ba a sami ƙarin abubuwan yi ba. Bi umarnin don amfani, bai lura da mummunan tasirin ba.
Mariya Utkova, 'yar shekara 34, Yekaterinburg
Dangane da thrombosis na basur lokacin daukar ciki, an wajabta wa ThromboAss aiki ne bayan an cire shi na cire jini. Babu wani karin magana game da basur, da kuma abin da ya faru na thrombosis. Hatta yanayin yanayi ya inganta. Ba a yarda kawai a ciyar da yaron da madara ba. Likitocin sun ce an adana maganin ta hanyar glandon dabbobi masu shayarwa kuma yana iya cutar da jikin da yake girma.
