Yadda za a yi amfani da miyagun ƙwayoyi Biosulin P?

Biosulin P wakili ne na glycemic wanda ya danganci aikin insulin na mutum. Latterarshen yana hade da godiya ga fasahar injiniyan ƙirar. Saboda tsarin da yayi kama da kwayar halitta ta koda, ana iya amfani da Biosulin don nau'in 1 da nau'in ciwon sukari na 2. Bangaren da ke aiki ba ya ƙetare cikin mahaifa, saboda haka, an ba da damar amfani da miyagun ƙwayoyi don gudanarwa yayin daukar ciki.

Sunan kasa da kasa mai zaman kansa

Jinin ɗan adam A cikin Latin - insulin ɗan adam.

Biosulin P wakili ne na glycemic wanda ya danganci aikin insulin na mutum.

ATX

A10AB01.

Saki siffofin da abun da ke ciki

An gabatar da maganin allurar kamar ruwa mara tsafta. A matsayin kwayar aiki, 1 ml na dakatarwar ya ƙunshi IU 100 na inulin da aka ƙera ɗan adam. Don daidaita pH na ruwa da kuma haɓaka bioavailability, ana amfani da kayan aiki mai aiki tare da abubuwan da aka haɗa:

• metacresol;
• ruwa bakararre;
• 10% maganin soda na caustic;
• maganin hydrochloric acid na maida hankali ne 10%.

Ana iya samar da biosulin a cikin kwalabe gilashi ko katako tare da ƙaramin 3 ml, waɗanda aka tsara don amfani dasu tare da sirinji na Biomatic Pen. Kunshin kwali ya ƙunshi kwantena 5 a cikin ɗaukar murfin huɗun.

Aikin magunguna

Insulin yana biye da tsarin kwayar halittar jikin mutum ta hanyar sake hadewar DNA. Tasirin hypoglycemic shine saboda ɗaure abu mai aiki ga masu karɓa a farfajiyar kwayar sel. Godiya ga wannan fili, an samar da hadaddun sel tare da insulin, wanda ke haɓaka aikin enzymatic na hexose-6-phosphotransferase, glycogen synthesis da gushewar glucose. A sakamakon haka, ana lura da raguwa a cikin ƙwayar glucose jini.

Biosulin P yana haɓaka samuwar glycogen da mai mai daga glucose, yana rage jinkirin aiwatar da gluconeogenesis a cikin hanta.

Ana samun sakamako na warkewa ta hanyar haɓaka yawan sukari ta tsokoki. An inganta zirga-zirgarsa a cikin sel. Samuwar glycogen da kitse mai narkewa daga glucose yana ƙaruwa, kuma aiwatar da gluconeogenesis a cikin hanta yana sauka a hankali.

Lokacin lissafin tasirin hypoglycemic yana lissafin gwargwado, wanda, bi da bi, ya dogara da wuri da hanyar gudanar da insulin, halayen mutum na masu ciwon sukari. Bayan aikin ƙarƙashin ƙasa, ana lura da tasirin warkewa bayan rabin sa'a kuma ya isa matsakaicin ƙarfin tsakanin 3 da 4 bayan amfani da katun. Tasirin hypoglycemic yana ɗaukar awanni 6-8.

Pharmacokinetics

Bioavailability da farkon aikin warkewa sun dogara da waɗannan abubuwan:

• hanyar aikace-aikacen - an yarda da allurar subcutaneous ko allurar intramuscular;
• yawan sinadarin hormone a ciki;
• wurin allura (dubura ciki, cinya na gaban kafa, gluteus maximus);
• insulin taro.

An rarraba kwayoyin halitta cikin tsari ba tare da daidaituwa ba a cikin jiki. An lalata aiki mai aiki a cikin hepatocytes da kodan. Rabin rayuwar shine minti 5-10. Abubuwan da ke aiki suna barin jiki a 30-80% tare da fitsari.

Gajeru ko tsayi

Insulin yana da ɗan gajeren sakamako.

Ana lissafin tsawon lokacin sakamako hypoglycemic bisa la'akari da ƙimar kimantawa.

Alamu don amfani

Ana iya gudanar da maganin a cikin halaye masu zuwa:

• ciwon sukari da ke dogaro da insulin;
• cututtukan da ba su da insulin-da ke dogara da asali game da ƙarancin tasirin magani, aikin jiki da sauran matakan rage nauyi;
• yanayi na gaggawa a cikin marasa lafiya da masu dauke da cutar sankara, wadanda ke dauke da nakuda ta hanyar hailaride metabolism.

Contraindications

An hana yin amfani da miyagun ƙwayoyi don rashin haɗin kai da kuma rashin haƙuri na mutum zuwa abubuwan da ke aiki da masu taimakawa.

Tare da kulawa

Wajibi ne a kula da matakin glucose akai-akai tare da tuntuɓi likita a cikin halaye masu zuwa:

• mai rauni na koda game da yiwuwar raguwar yiwuwar buƙatar insulin a kan bangon metabolism dinsa mai rauni;
• tsufa, tunda tsawon shekaru aikin kodan ya ragu;
• rauni na zuciya;
• cututtuka ko gazawar hanta da ke haifar da raguwa a cikin gluconeogenesis;
• mai tsananin ƙarfi na jijiyoyin zuciya da jijiyoyin wuya;
• shan kashi ta hanyar farfadowa da farfadowa ba tare da maganin warkewa tare da daukar hoto ba, cutar tare da haɓakar ƙwaƙwalwar ƙwayar cuta yana ƙara haɗarin cikakken makanta;
• cututtukan sakandare waɗanda ke rikita yanayin ciwon sukari da kuma ƙara buƙatar insulin.

A cikin gazawar ƙirar mai girma, yakamata a sha magani tare da taka tsantsan.

Rashin lafiyar zuciya na yau da kullun shine dalilin yin amfani da miyagun ƙwayoyi Rinsulin R.

Don cututtuka ko gazawar hanta, ana ɗaukar Rinsulin P tare da taka tsantsan.

An dauki Rinsulin P tare da taka tsantsan idan mai haƙuri yana da jijiyoyin jijiyoyin zuciya da jijiyoyin wuya.

Ya kamata a ɗauka Rinsulin P tare da taka tsantsan a cikin tsufa.

Yadda ake ɗaukar Biosulin P

Yawan kwararrun likitoci suna daukar matakin ne akan kowane mutum, gwargwadon alamu na sukari na jini. An yarda da sarrafa kwayar halitta ta biosulin a cikin yanki, a wurare tare da zurfin ɓangaren tsokoki da cikin jijiyoyin ciki. Matsakaicin da aka ba da shawarar yawan amfanin yau da kullun ga manya shine 0.5-1 IU a kowace 1 kilo na nauyi (kimanin raka'a 30-40).

Masana ilimin likita suna ba da shawara ga gudanar da magunguna mintina 30 kafin a fara cin abinci mai ɗauke da ƙwayoyi. A wannan yanayin, zazzabi na miyagun ƙwayoyi da aka sarrafa ya kamata yayi daidai da zafin jiki na yanayi. Lokacin monotherapy tare da Biosulin, ana gudanar da wakili na hypoglycemic sau 3 a rana, a gaban abubuwan ciye-ciye tsakanin abinci, yawan injections yana ƙaruwa sau 5-6 a rana. Idan sashi ya wuce 0.6 IU a 1 kg na nauyin jiki, ya zama dole a sanya allura guda 2 a sassa daban daban na jikin ba a yanki daya na jikin mutum ba.

Wajibi ne a yi amfani da magani a karkashin fata a saman tsokoki na ciki, tare da dabarun aiwatar da ayyukan:

1. A wurin gabatarwar da aka gabatar, kuna buƙatar tattara fata a cikin crease ta amfani da babban yatsa da goshin hannu. Dole a saka allurar sirinji a cikin ninka fata a wani kusurwar 45 ° kuma piston ya yi ƙasa.
2. Bayan gabatarwar insulin, kuna buƙatar barin allura a ƙarƙashin fata har tsawon 6 ko fiye don tabbatar da cewa an sarrafa maganin gaba daya.
3. Bayan cire allura, jini na iya fitowa a wurin allurar. Yankin da abin ya shafa yakamata a matse tare da yatsa ko auduga ulu da aka sanyaya da barasa.

Haka kuma, kowane allurar dole ne a aiwatar da shi tsakanin iyakokin yankin ilimin halittar jiki, canza wurin allurar. Wannan ya zama dole don rage yiwuwar lipodystrophy. Injection na ciki da allurar cikin jijiya ne kawai ke gudana daga kwararrun likitoci. An haɗa insulin gajere da wani nau'in insulin tare da sakamako mai warkewa.

Tare da monotherapy tare da Biosulin, ana gudanar da wakili na hypoglycemic wakili sau 3 a rana.

Sakamakon sakamako na Biosulin P

Bayyanancin sakamako masu illa yana faruwa ne sakamakon amsawar jikin mutum ga aikin, magani ne ba daidai ba ko gabatar da allura.

Daga gefen metabolism

Hypoglycemic syndrome halin:

• cyanosis;
• karuwar gumi;
• tachycardia;
• rawar jiki;
• yunwa;
• karuwar wuce gona da iri;
• ku ɗanɗani paresthesia;
• ciwon kai;
• rashin lafiyar hailala.

Cutar Al'aura

A cikin marasa lafiya da rashin lafiyar ƙwayar nama zuwa tsarin mahaɗin na miyagun ƙwayoyi, angioedema na makogwaro da halayen fata na iya haɓaka. A cikin lokuta mafi wuya, girgiza anaphylactic na iya faruwa.

Sweara yawan zagewa shine tasirin sakamako na miyagun ƙwayoyi Rinsulin R.

Rinsulin P na iya haifar da tachycardia.

Wasu lokuta Rinsulin P yana haifar da ciwon kai.

Cutar Hypoglycemic coma tana dauke da cutar sikila wacce take faruwa lokacin shan Rinsulin R.

A cikin halayen da ba a sani ba, girgiza ƙwayar cuta na iya faruwa daga ɗaukar Rinsulin P.

Tasiri kan ikon sarrafa abubuwan inji

Magungunan ba ya shafar ikon sarrafa abubuwa masu rikitarwa. Sabili da haka, yayin glycemic therapy, tuki ko aiki tare da kayan aikin kayan wuta ba a hana su ba.

Umarni na musamman

Ba za ku iya shigar da mafificin girgije ba, magani ne da ya canza launi ko ya ƙunshi tabbatattun jikin ƙasashen waje. A lokacin maganin insulin, ya zama dole don sarrafa matakin sukari na jini.

Hadarin yanayin hypoglycemic yana ƙaruwa a cikin waɗannan halaye masu zuwa:

• canzawa zuwa wani wakili na hypoglycemic ko wani nau'in insulin;
• Abinci mai tsallakewa;
• rashin ruwa a dalilin gudawa da gudawa;
• haɓaka aiki na jiki;
• cututtukan cikin jiki;
• raguwa a cikin ɓoyewar hormonal na cortex adrenal;
• canji a fannin gudanarwa;
• hulɗa tare da wasu magunguna.

Idan ba a yi maganin da ya dace ba, hyperglycemia na iya haifar da faruwar cutar ketoacidosis mai ciwon sukari.

Abubuwan da ke tattare da cututtukan cututtukan cututtukan ciki, musamman na yanayin kamuwa da cuta, ko yanayi wanda ci gaban zazzabi ya karu, yana buƙatar buƙatun ƙwayar jikin insulin. Ya kamata a aiwatar da wani abu na maye gurbin biosulin tare da wani nau'in insulin na mutum a karkashin tsauraran iko na sukari na jini.

Rashin haɗarin yanayin hypoglycemic yana ƙaruwa yayin yanayin hulɗa tare da wasu magunguna.

Dole a sanya magani sosai a cikin halaye masu zuwa:

• rage yawan aiki na glandar thyroid;
• hanta ko cutar koda;
• Cutar Addison;
• shekaru sama da 60;
• increasedara yawan aiki a jiki ko canji a abinci.

Magungunan yana rage haƙuri da kyallen takarda zuwa sakamakon ethanol.

Yi amfani da lokacin daukar ciki da lactation

Inulin da aka ƙera ta ƙarancin jini ba ya ratsa bakin ƙwaryar cikin mahaifa, wanda ba ya keta ci gaban tayin na halitta. Saboda haka, ba a hana maganin insulin ba a lokacin daukar ciki. Magungunan ba ya shiga cikin gland na dabbobi masu shayarwa kuma ba a keɓance shi a cikin madara ba, wanda ke ba wa mata masu juna biyu damar shiga Biosulin ba tare da tsoro ba.

Yi amfani da tsufa

Tsofaffi mutane saboda raguwa da suka shafi tsufa a cikin aikin koda koda yaushe suna buƙatar sarrafa matakan sukari na jini.

Adana Biosulin P ga yara

A cikin ƙuruciya, ana ba da shawarar gabatarwar rukuni 8 na miyagun ƙwayoyi.

Yawan adadin kwayoyin Biosulin P

Tare da amfani da babban adadin insulin, hypoglycemia na iya faruwa. Za a iya rage ƙananan raguwar taro a cikin kanku ta cin sukari ko abinci mai cike da carbohydrate. Saboda wannan, ana ba da shawarar marasa lafiya da ke da nau'in ciwon sukari na 2 don ɗaukar gari ko kayan kwalliya, ruwan 'ya'yan itace da sukari.

Idan mai haƙuri ya rasa hankali, to, mummunan ciwo na hypoglycemia ya faru. A wannan yanayin, gudanar da kai tsaye na 40% na glucose ko kuma bayani na dextrose, 1-2 mg na glucagon cikin hanji, subcutaneously ko intramuscularly wajibi ne. Lokacin dawo da hankali, ya zama dole a ba wa wadanda abin ya shafa abinci mai yawa a cikin carbohydrates don rage haɗarin sake dawowa.

Idan mai haƙuri ya rasa hankali, to, mummunan ciwo na hypoglycemia ya faru.

Yin hulɗa tare da wasu kwayoyi

Amfani da barasa

Ethyl barasa ya cutar da tsarin jijiyoyin jini da kuma aikin hanta da kodan. A sakamakon haka, rushewar ƙwayar insulin, wanda zai haifar da asarar sarrafa glycemic. Yiwuwar samun hauhawar jini yana ƙaruwa. Sabili da haka, a lokacin magani tare da miyagun ƙwayoyi, an haramta shan giya.

Analogs

Ana iya maye gurbin miyagun ƙwayoyi ta hanyar nau'ikan insulin masu saurin aiki:

• Insuman Rapid GT;
• Actrapid NM Penfill;
• Gensulin P;
• Tsarin Humulin.

Magunguna kan bar sharuɗan

Za'a iya siye maganin ta hanyar takardar sayan magani.

Zan iya siye ba tare da takardar sayan magani ba

Ba daidai ba sashi zai iya haifar da ci gaban hypoglycemia har zuwa farkon ƙwayar cutar sankara, saboda haka, ana sayar da maganin don dalilai na likita kai tsaye.

Farashi don Biosulin P

Matsakaicin matsakaici don shiryawa tare da kwalabe shine 1034 rubles.

Yanayin ajiya na miyagun ƙwayoyi

An ba da shawarar kiyaye katako da ampoules tare da insulin a zazzabi na + 2 ... + 8 ° C a wani wuri da keɓe daga haske tare da ƙaramin zafi.

Ranar karewa

Watanni 24. Bayan buɗe ampoule za'a iya adana shi na kwanaki 42, katako - kwana 28 a zazzabi na + 15 ... + 25 ° C.

Mai masana'anta

Marvel LifeSines, India.

Ra'ayoyi game da Biosulin P

Magungunan sun kafa kanta a cikin kasuwar magunguna saboda kyakkyawan sakamako daga likitoci da marasa lafiya.

Analog na Rinsulin P ana ɗauka Insuman Rapid GT.

Humulin Alamar yau da kullun ta magani Rinsulin R.

Actrapid NM Penfill an dauke shi analogue na miyagun ƙwayoyi Gensulin R.

Gensulin R - analog na maganin Rinsulin R.

Likitoci

Elena Kabluchkova, endocrinologist, Nizhny Novgorod

Ingantaccen magani na insulin wanda ke taimakawa tare da hyperglycemia na gaggawa a cikin masu ciwon sukari. Alƙalin sirinji ya dace wa marasa lafiya da jigilar jigilar rayuwa da aiki. Wani ɗan gajeren aiki yana taimaka wajan hanzarta magance babban sukari. Ta hanzarta cimma sakamako mai warkewa, zaku iya amfani da katun kafin cin abinci. An yarda da biosulin don amfani dashi tare da wasu kwayoyi dangane da insulin aiki na tsawon lokaci. Marasa lafiya na iya karɓar magani a ragi.

Olga Atamanchenko, endocrinologist, Yaroslavl

A cikin aikin asibiti, Ina kan tsara magunguna tun daga Maris 2015. Tare da shigowar wannan nau'in insulin a cikin masu ciwon sukari, ingancin rayuwa yana inganta, da yiwuwar hauhawar jini da hauhawar jini. An ba da izinin amfani dashi a cikin yara da mata masu juna biyu. Godiya ga insulin gajere, mai haƙuri na iya gudanar da maganin a cikin yanayin gaggawa (tare da matakan sukari). Ina tsammanin Biosulin magani ne mai sauri, mai inganci.

Masu ciwon sukari

Stanislav Kornilov, mai shekara 53, Lipetsk

Ingantaccen gajeran aiki insulin. Na yi amfani da Gensulin da Farmasulin, amma zan iya samun kyakkyawan raguwa a cikin taro na glucose kawai godiya ga Biosulin. Magungunan ya tabbatar da kansa a hade tare da Insuman Bazal - insulin na dogon lokaci. Godiya ga saurin tasirin, Na sami damar faɗaɗa abincin 'ya'yan itatuwa. Na lura cewa daga magunguna na baya kaina kaina yakan ji rauni, amma ba a lura da wannan sakamako ba. Na gamsu da sakamakon, amma babban abu shi ne bin umarnin don amfani da abincin da aka tsara.

Oksana Rozhkova, mai shekara 37, Vladivostok

Shekaru 5 da suka gabata, tana cikin kulawa mai zurfi dangane da lalata yanayin ciwon sukari, wanda ba ta sani ba.Bayan cimma nasarar sarrafa glycemic, likita yayi magana game da ganewar asali kuma ya wajabta Biosulin akan ci gaba mai gudana. Ya ce ya fi dacewa a yi amfani da maɓallin sirinji. Yayin da aka yi maganin, maganin sukari ya kasance a cikin iyaka. Amma wannan nau'in insulin gajere ne, kuma ya wajaba a zabi wani nau'in tare da sakamako mai tsayi. Na ji tsoron cewa magungunan ba za su dace ba, amma ba a tabbatar da shakku ba. Yana da kyau don haɗuwa da wani nau'in insulin.