Angiocardyl wani tsari ne na metabolism. Yana da amfani mai amfani ga aikin zuciya, yana ƙara ƙarfin jimami, yana kare damuwa daga damuwa, amma ba a iya daidaita shi da kwayoyi ba. Ana amfani dashi a cikin hadaddun hanyoyin cututtukan cututtukan zuciya, a cikin maganin ophthalmology da kuma taimakawa tare da alamun cirewa.
Sunan kasa da kasa mai zaman kansa
Dangane da ka'idodin da WHO ta gindaya, an ba INN don abu mai aiki. Saboda haka, sunan duniya na miyagun ƙwayoyi shine Meldonium.
Angiocardyl yana da amfani mai amfani ga aikin zuciya, yana ƙaruwa da juriya, yana kare damuwa daga damuwa, amma ba a iya daidaita shi da magungunan doping ba.
ATX
Wannan magani yana cikin rukunin magungunan metabolites kuma yana da lambar ATX na C01EB.
Saki siffofin da abun da ke ciki
Ana samar da maganin ta hanyar samar da mafita don allura tare da taro mai aiki na 100 mg / ml. 5 ml marufi. Ana sanya ampoules na gilashi a cikin kwali na kwali na guda 10. tare da ampoule wuka / mai ruwa da kuma littafin bayani. Babban abun ciki na angiocardyl shine meldonium dihydrate. Magabatar ruwa tsarkakakken ruwa ne wanda aka shirya don shirye-shiryen rigakafin allura.
Hakanan ana samar da miyagun ƙwayoyi a cikin nau'i na capsules na 500 MG a cikin kwasfa gelatin mai wuya. An cika su da farin hygroscopic foda tare da ƙanshin ƙanshin wari. Abubuwan taimako: sitaci, alli na sitarate, nau'in colloidal na silicon dioxide. Capsules 10 inji mai kwakwalwa. sanya shi a cikin blisters kuma an gyara shi tare da tsare. Blisters na kwamfutoci 2 ko 6. shimfiɗa su cikin kwali. Umarni a haɗe yake.
Hakanan ana samar da miyagun ƙwayoyi a cikin nau'i na capsules na 500 MG a cikin kwasfa gelatin mai wuya.
Hakanan akwai nau'in kwamfutar hannu na angiocardyl. Babban gabatarwar an gabatar dashi a cikin nau'in phosphate, kuma ƙarin abun da ke ciki ya haɗa da mannitol, sitacin dankalin turawa, magnesium stearate, microcrystalline cellulose da silicon dioxide. Ana sanya allunan 500 MG a cikin blisters na 10 inji mai kwakwalwa.
Hakanan zaka iya samun maganin a cikin nau'i na syrup don maganin baka.
Aikin magunguna
Abun aiki na Angiocardyl shine meldonium. A cikin tsarin sa, yayi kama da gamma-butyrobetaine (GBB), wanda aka haɗu a cikin jiki a cikin yanayi mai wahala, gami da rashin isashshen sunadarin oxygen.
Ta hana enzyme gamma-butyrobetaine hydroxynase, meldonium ya toshe tsarin carnitine, wanda ke da alhakin jigilar mayukan kitse zuwa ƙwayoyin zuciya. Ressionarfafa aikin sufuri yana da mahimmanci ga rashi oxygen, saboda a wannan yanayin, ana lura da hadafin hada hada abubuwa da abubuwa masu ƙima tare da samuwar matsakaitan matsakaici wanda ke cutar da zuciya. Misali, sun toshe shigowar kwayoyin halittar ATP cikin sel.
Rage yawan carnitine yana ƙarfafa haɓakar haɓaka na GBB, wanda ke nuna vasodilating kaddarorin, da katsewa a cikin samar da kitse mai yawa wanda ya haifar da raunin carnitine yana haifar da gaskiyar cewa ana samar da makamashi a yanayin ceton oxygen. Nazarin ya nuna cewa saboda waɗannan kaddarorin, meldonium yana ƙaruwa da ƙarfin aiki da jimiri, yana hanzarta murmurewa bayan motsa jiki, inganta aikin mai motsa jiki, yana ƙarfafa ayyukan tsarin juyayi na tsakiya, kuma shine cardioprotector.
Tare da ischemic bugun jini, miyagun ƙwayoyi yana inganta kunnawa na yaduwar hanji, yana rage yanki na lalacewar ƙwayoyin cutar ƙwaƙwalwa.
A cikin bugun jini na ischemic, ƙwayar ta inganta kunnawa na yaduwar hanzari, rage yanki na lalacewar necrotic ga ƙwaƙwalwar kwakwalwa kuma yana rage tsawon lokacin haƙuri. Yana da ikon rage tasirin cututtukan angina, haɓaka matakin halatta na motsa jiki a cikin rauni na zuciya, matakin alamun bayyanar cututtuka. Ana amfani da wannan kayan aikin a likitan ido. Anan ana amfani dashi don kawar da wasu cututtukan jijiyoyin bugun gini.
Pharmacokinetics
Daga gastrointestinal fili, ana amfani da maganin a cikin awanni 1-2, yana kaiwa matsakaicin yawan ƙwayar cutar plasma kusan 78%. Lokacin da aka kawo kai tsaye zuwa cikin jini, bioavailability na meldonium shine 100%. Metabolization wannan fili yana faruwa a cikin hanta. Kodan an fi fitar da maganin ne tsawon awanni 6-12. A babban sigogi, cikakken tsabtace jiki zai iya ɗaukar watanni da yawa, amma a lokaci guda, ƙaramin taro akan abubuwan zai kasance.
Alamu don amfani
An nuna magungunan don amfani a cikin lokuta na kara gajiya, yayin nauyi na jiki, hankali ko damuwa, ciki har da wasan motsa jiki. Ya kamata a sani cewa Hukumar Anti-Doping ta hada shi a cikin jerin kayayyakin da 'yan wasa suka haramta amfani dasu yayin shirya da kuma gudanar da gasa. Ba a tabbatar da wannan shawarar gaba ɗaya ba, tun da meldonium baya bada izinin ƙara kaya ko tsawan horo, amma kawai yana ba da gudummawa ga murmurewa mai sauri bayan horo mai zurfi.
An nuna magungunan don amfani a cikin lokuta na kara gajiya, yayin nauyi na jiki, hankali ko damuwa, ciki har da wasan motsa jiki.
Likitoci sun haɗa da wannan magani a cikin hadaddun jiyya don irin wannan cututtukan:
- cututtukan zuciya da na jijiyoyin jini;
- angina pectoris;
- karancin lalacewa;
- bayyanar cututtuka na rashin ƙarfi na zuciya;
- wulakanci cardiomyopathy;
- bugun jini;
- haɗarin mahaifa;
- karban ciwo.
A cikin maganin ophthalmic, amfanin Angiocardil yana da tasiri don lura da:
- bashin jini;
- hemophthalmus;
- kashin baya na thrombosis;
- nau'ikan nau'ikan maganin cututtukan fata;
- dystrophic pathologies na fundus.
A cikin aikin ophthalmic, yin amfani da Angiocardil yana da tasiri don magance cututtukan cututtukan mahaifa, haemophthalmus, retinal vein thrombosis, da sauransu.
Contraindications
Susara mai saukin kamuwa da aiki na ƙwayar meldonium ko abubuwan taimako na maganin shine tsayayyen contraindication ga amfani da angiocardyl a kowane nau'i. Ba za a iya ɗaukarsa a wasu lokuta ba. Yardajewa:
- babban matsa lamba intracranial;
- ciwan ciki;
- take hakki na fitar da kwakwalwa mai kwakwalwa;
- lokacin haihuwar jariri;
- shayarwa;
- shekaru zuwa shekaru 18.
A gaban na koda ko hepatic mahaukacin, ya kamata a wajabta miyagun ƙwayoyi tare da taka tsantsan.
Yadda ake ɗaukar angiocardil
Hanyar da aka fi so don gudanar da maganin, maganin ta da kuma tsawon lokacin ta hanyar likita an ƙayyade su daban-daban. Sakamakon yiwuwar sakamako mai ban sha'awa na meldonium akan tsarin juyayi na tsakiya, ana bada shawara don canja wurin amfani dashi zuwa farkon rabin rana. Game da amfani na rarrabe, kashi na ƙarshe ya kamata ba zai wuce 1700 ba.
Ana sarrafa magungunan allura ne a cikin tazara ko a cikin tazara. Bayan haka (idan ya cancanta) sai su sauya zuwa shan nau'in angiocardyl. A wasu halaye, ana iya rage takaddun ƙwayar cuta guda ɗaya, rage zuwa 125-250 MG. Idan ya cancanta, ana maimaita magani bayan makonni da yawa. Kamar yadda likita ya umarta, ana iya gudanar da aikin warkewa sau 2-3 a shekara.
Ana sarrafa magungunan allura ne a cikin tazara ko a cikin tazara.
A cikin maganin ophthalmology, ana amfani da magani don keɓaɓɓen don gudanar da aikin parabulbar. A cikin buguwa ta giya, maganin baka na allunan ko capsules da kuma gudanar da allurar angiocardil injections mai yiwuwa ne.
Tare da ciwon sukari
Ana iya ba da magani ga masu ciwon sukari. Meldonium ya sami damar rage yawan sukarin jini ba tare da kara yawan insulin ba. Karbarsa yana ba ka damar hana lalatawar ƙwayar cuta, asarar ji, ci gaban acidosis. Amfani da layi daya na angiocardyl tare da kwayoyi irin su metformin, tare da juna suna haɓaka tasirin hypoglycemic na magungunan biyu.
Sakamakon sakamako na angiocardyl
Magungunan suna da haƙuri da haƙuri, amma wani lokacin bayyanar alamun rashin lafiyan, kamar su:
- rash, urticaria;
- erythema;
- fata mai ƙyalli;
- ci gaban puffiness.
Lokacin gudanar da gwajin jini, haɓaka haɗuwa da ƙwayoyin eosinophilic farin jini. A cikin lokuta mafi wuya, marasa lafiya suna korafi game da fashewa.
Gastrointestinal fili
Juyayin jijiyoyin jiki yakan faru wasu lokuta, rashin jin daɗi ko jin zafi a cikin jijiyar epigastrium, kuma jin cikewar ya tashi a ciki. Mai haƙuri na iya jin rashin lafiya.
Tsarin juyayi na tsakiya
Daga cikin halayen juyayi, karuwar damuwa, barkewar tashin hankali, tsananin tashin hankali, da rashin bacci mai yiwuwa ne.
Daga tsarin zuciya
Matsi na iya bambanta a wani bangare ko wata. Da kyar ake lura da ƙaruwa sosai a cikin zuciya.
Tasiri kan ikon sarrafa abubuwan inji
Babu bayanai game da mummunan tasirin da miyagun ƙwayoyi ke da shi game da ikon tuƙi motoci da hanyoyin keɓaɓɓu. Amma saboda yiwuwar bayyanar cututtukan juyayi da ba a iya faɗi ba yayin jiyya tare da Angiocardil, ana ba da shawarar guji irin waɗannan ayyukan.
Lokacin ɗaukar Angiocardil, matsin lamba na iya canzawa a wani shugabanci ko wata, karuwa a cikin zuciya yana da wuya a lura.
Umarni na musamman
A cikin bayyanannun bayyanar cututtuka na cututtukan jijiyoyin zuciya, ba a fifita shirye-shiryen meldonium, amfani da su ba na zaɓi bane.
Yi amfani da tsufa
Magungunan zai iya haifar da tachycardia matsakaici. Sabili da haka, ya kamata a yi amfani dashi game da tsofaffi tare da taka tsantsan, ba da damar hulɗa da miyagun ƙwayoyi, da yanayin yanayin hanta da mai koda.
Aiki yara
Ba'a tabbatar da ingantaccen maganin ciwon angiocardil a cikin yara ba. Bayanai game da amincin amfanin da yake da shi a cikin ilimin rayuwar yara suma sun ɓace. Sabili da haka, ba a ba da magunguna ga marasa lafiya da ke ƙasa da shekara 18. Iyakar shekaru don ɗaukar meldonium a cikin nau'in syrup shine shekaru 12.
Yi amfani da lokacin daukar ciki da lactation
Ba a fayyace sakamakon ci gaban angiocardil kan ci gaban tayin ba ta hanyar gwaji. Dangane da wannan, mata masu juna biyu ya kamata su guji wa’adin da aka nada. Babu wata shaidar ko miyagun ƙwayoyi suna iya wucewa cikin madara. Game da batun wucewa ta hanyar jiyya, mahaifiyar ta kamata ta yi watsi da shayar da jarirai na wani dan lokaci.
Aikace-aikacen aiki mara kyau
A gaban ƙwayoyin cuta na koda, ɗauki magani tare da taka tsantsan.
Amfani don aikin hanta mai rauni
Rashin isasshen hepatic yana haifar da raguwa a cikin metabolism na meldonium da haɓaka cikin taro a cikin plasma. Sabili da haka, marasa lafiya da cutar hanta ya kamata su kasance a ƙarƙashin kulawa ta musamman, musamman tare da doguwar jiyya tare da angiocardil.
Adadin yawa na Angiocardil
Yawan wuce haddi na miyagun ƙwayoyi ya bayyana:
- karancin jini;
- tachycardia;
- ciwon kai;
- rushewa;
- farin ciki.
Idan irin waɗannan alamun suka bayyana, nemi likita. Maganin farji idan aka sami matsalar yawan amfani da cuta sama da niyyar kawarda alamun da ke akwai.
Yin hulɗa tare da wasu kwayoyi
Meldonium a hade tare da glycosides na zuciya, magungunan antihypertensive da magungunan da ke haifar da fadada tasoshin jijiyoyin jini, haɓaka tasirin waɗannan kwayoyi. Akwai haɗarin haɓaka aikin hypotonic tare da tachycardia, sabili da haka, ya kamata a yi taka tsantsan lokacin da ake rubuta Angiocardil tare da adrenergic blockers, nitroglycerin da na gefe mai gudana na jini na jijiyoyin bugun jini, magungunan antihypertensive, magungunan alli.
Meldonium a hade tare da glycosides na zuciya, magungunan antihypertensive da magungunan da ke haifar da fadada tasoshin jijiyoyin jini, haɓaka tasirin waɗannan kwayoyi.
Hadin magunguna da ake tambaya tare da irin wadannan kungiyoyin magunguna abin yarda ne:
- wakilan antiplatelet;
- kwastomomi;
- kamuwa da cuta;
- maganin cututtukan jini;
- magungunan antianginal;
- magungunan antiarrhythmic.
Amfani da barasa
A lokacin jiyya, ya kamata ka ƙi shan giya da kwayoyi masu ɗauke da giya.
Analogs
Meldonium wani bangare ne na magunguna tare da sunaye iri-iri na kasuwanci:
- Kapikor;
- Olvazole;
- Idrinol;
- Mildronate;
- Kwayoyin Meldonium;
- Cardionate;
- Midolate;
- Medatern;
- Mildrocard da sauransu
Magunguna kan bar sharuɗan
Sayar da kayayyaki yana da iyaka.
Sauran kwayoyi waɗanda suka haɗa da meldonium, alal misali, Idrinol, na iya zama analogues na maganin angiocardil.
Zan iya siye ba tare da takardar sayan magani ba
Ana ba da magani tare da takardar sayan magani.
Farashi
Kudin angiocardyl daga 262 rubles. na ampoules 10.
Yanayin ajiya na miyagun ƙwayoyi
Dole ne a kiyaye miyagun ƙwayoyi a cikin duhu a zazzabi na +15 zuwa + 25 ° C. Ya kamata ku iyakance damar yara ga magunguna da hana danshi shiga allunan da maganin kawa.
Ranar karewa
Maganin allurar ya dace da shekara 2 daga ranar da aka ƙera shi. Rayuwar shiryayye na nau'in maganin baka shine shekaru 4. An hana amfani da samfuran ƙarewa.
Mai masana'anta
Mai kera kaya a Rasha - Novosibkhimpharm OJSC, a Latvia - Grindeks JSC.
Nasiha
Amelina A.N., babban likitan, Voronezh
Wannan magani yana da tasiri kuma ba shi da tsada. Sau da yawa nakan sanya shi a cikin majinyata na tsawon lokacin aikin tiyata na bayan haihuwa. Yana ba ku damar samun ƙarfi a cikin mafi ƙarancin lokacin da zai yiwu. Shekaru na gwaninta sun tabbatar da amincinsa. Abubuwan da ke haifar da sakamako masu guba suna da wahalar gaske.
Valentine, dan shekara 34, Penza
Ina aiki kusan kwana bakwai a mako; Ban yi hutu ba shekaru da yawa. Da yamma ina durƙusa, kuma ina buƙatar in kula da jikina, saboda kusan ba na tashi daga tebur. Maganin ya zo a cikin hanyar Angiocardil. Na ji irin wannan ƙarfin ƙarfin, kamar in ƙarami shekaru na dozin. Yanzu na je wurin motsa jiki sau uku a mako kuma a lokaci guda ban gaji da gaske.
Daria, shekara 52, Moscow
Ta yi aikin tiyata a zuciya. Sake dawowa na da tsawo kuma mai raɗaɗi, na kasance mai rauni a koyaushe. Nadin Angiocardil ya ba da sakamako mai kyawu.Ta fara jin murmushin jin dadi, yanayin kuncin da take ciki ya gushe gaba daya.
Anastasia, ɗan shekara 31, Ekaterinburg
Ta yi karatun 2 na jiyya tare da angiocardil tare da tazara tsakanin makonni 3. Fewan kwanakin farko akwai ɗan tashin hankali bayan ɗaukar capsules, to ba a lura da tasirin da bai dace ba. Kawai kar a sha maganin a maraice, in ba haka ba zai zama da wuya a yi bacci. Sakamakon ya gamsar. Ya zama ƙasa da damuwa ga zuciya, wanda sau da yawa yakan baci daga wuri, Zan iya zuwa dama zuwa bene na 5 ba tare da matsanancin numfashi ba kuma samun isasshen bacci a cikin awanni 5-6.
Alexey, dan shekara 39, Evpatoria
Na sayi capsules don inna, an lura da kyawawan canje-canje nan da nan. Kashegari, ta yi kira da godiya ga likitan. Ya ce numfashi ya zama da sauki, an share shi a cikin kai kuma mafi annashuwa a zuciya. Muna fatan karin sakamako na magani.
