Gluconorm shine ɗayan magungunan da aka ɗauka don bi da ciwon sukari na 2. Magungunan yana da tasirin hypoglycemic.
Gluconorm yana samuwa a cikin kwamfutar hannu kuma an yi niyya don maganin baka.
Bayani na gaba ɗaya, abun da ya shafi da kuma sakin sakewa
Gluconorm wani nau'in magungunan gargajiya ne wanda aka kera a Indiya. Baya ga tasirin hypoglycemic, ƙwayar tana taimakawa rage ƙananan ƙwayar cholesterol a cikin jinin mai haƙuri.
An ba shi izinin rarraba kuɗi ta takardar sayen magani na ƙwararren likita. Ana amfani da maganin har tsawon shekaru 3 daga ranar da aka ƙera shi.
Wajibi ne a lura da yanayin ajiya na wannan magani. An adana shi a cikin duhu ba tare da samun damar yara ba. Mafi yawan zafin jiki na ajiya shine 20-230C.
Bugu da ƙari, Gluconorm tare da ruwan hoda na fure a cikin shayi na ganye an samar da shi, wanda ba magani bane, amma ana ɗaukar shi azaman rage yawan sukari.
Babban abubuwan magungunan sune Metformin Hydrochloride da Glibenclamide. Abun cikin abubuwan farko a cikin kwamfutar hannu 1 shine 400 MG, na biyu - 2.5 MG. Cellulose a microcrystals da silloon silicon dioxide suna halarta a matsayin ƙarin abubuwa a cikin abubuwan da aka shirya. Hakanan an lura da halayen croscarmellose, diethyl phthalate da glycerol.
Daga cikin sauran abubuwan haɗin maganin, an lura da sodium carboxymethyl sitaci, magnesium stearate da cellacephate. A wasu takamaiman, talc tare da sitaci na masara da gelatin yana cikin halayen magunguna.
Packaya daga cikin fakitin Allunan yana dauke da blister 1-4. A cikin blister na iya zama allunan 10, 20, 30 na maganin. Allunan maganin suna da fari kuma suna da sifar zagaye na biconvex. A lokacin hutu, allunan na iya samun ɗanɗano launin toshiya mai ɗanɗano.
Gluconorm blueberry tea bai ƙunshi abubuwan da ake gabatar dasu a allunan ba. An yi shi ne daga ganyayyaki na halitta kuma ana sayar dashi a cikin nau'i na jakunan shayi. An tsara hanya don 3 makonni.
Pharmacology da pharmacokinetics
Gluconorm ya ƙunshi manyan abubuwan biyu: Glibenclamide da Metformin. Duk abubuwan guda biyu suna aiki a cikin haɗin haɗin gwiwa, yana haɓaka tasiri na miyagun ƙwayoyi.
Glibenclamide shine asalin ƙarni na biyu na tushen sulfonylurea. Sakamakon aikinsa, ƙwayar insulin yana motsawa, kuma yana ɗaukar insulin ƙwayar cutar ta ƙara ƙaruwa a cikin ƙwayoyin manufa.
Glibenclamide yana haɓaka aikin fito da insulin kuma yana inganta tasirinsa akan sha na glucose ta hanta, haka kuma ta tsokoki. A karkashin aikin wani abu, aiwatar da rarrabuwar kitse a cikin tsose kyallen takarda yayi saurin sauka.
Metformin abu ne na biguanide. Sakamakon aikinsa, rage yawan glucose a cikin jinin mara lafiya, akwai karuwar karuwar glucose ta gabobin yankin.
Abubuwan sun fi dacewa da rage yawan ƙwayar cholesterol. Sakamakon ayyukan Metformin, yawan shan carbohydrates a cikin ciki da hanji yana raguwa. Abubuwa masu matukar muhimmanci suna hana samuwar glucose a cikin hanta.
Glibenclamide da Metformin, waɗanda suke ɓangare na miyagun ƙwayoyi, suna da magunguna daban-daban.
Yawan sha daga glibenclamide bayan shigowa daga ciki da hanjinsa ya kai kashi 84%. Matsakaicin maida hankali na kashi ana iya kaiwa cikin awa daya ko biyu. Abubuwan suna da alaƙa da sunadarai na jini. Adadin shine kashi 95%. Mafi karancin rabin rayuwa shine 3 hours, matsakaicin shine 16 hours. Kodan ya rabu da sashin jikinta, wani ɓangare kuma hanjin hancin.
Matsakaicin bioavailability na Metformin bai wuce 60% ba. Cin abinci yana rage jinkirin rage sinadarin metformin. Duk wani abu da aka ɗauka akan komai a ciki yana narkewa daga ciki da hanji.
Ba kamar Glibenclamide ba, yana da ƙananan ɗauri don garkuwar jini. Kodan ya fice. 30% na kayan na iya kasancewa a cikin yanayin mai haƙuri. Cire rabin rayuwa ya kai awa goma sha biyu.
Manuniya da contraindications
Babban nuni ga shan wannan magani shine kasancewar nau'in ciwon sukari na II a cikin haƙuri. Hakanan, an wajabta magungunan a cikin rashin tasirin sakamako na dacewa tare da abinci, motsa jiki da jiyya bisa ga shan Metformin tare da Glibenclamide.
Hakanan ana nuna magungunan ga marasa lafiya waɗanda ke da sukari na jini da na yau da kullun, amma waɗanda ke da buƙatar maye gurbin jiyya tare da Glibenclamide da Metformin.
Babban adadin contraindications halaye ne na magani:
- gazawar hanta;
- raguwa a cikin taro na sukari na jini (hypoglycemia);
- babban hankali ga abubuwan da ke cikin magani;
- nau'in ciwon sukari na mellitus;
- na kullum mai shan giya;
- ciki
- lalacewar aikin na yara saboda kamuwa da cuta, rawar jiki;
- ketoacidosis;
- amfani da miconazole;
- gaban konewa a jiki.
- bugun zuciya;
- shayarwa;
- cututtuka daban-daban;
- coma mai cutar kansa;
- gazawar koda
- karancin lalacewa;
- yi aikin tiyata;
- lactic acidosis;
- giya barasa;
- gazawar numfashi;
- precoma na ciwon sukari;
- cutar porphyrin.
Umarnin don amfani
Ana ɗaukar magunguna tare da abinci. Ga kowane mai haƙuri, an kafa sashi ɗaya na Gluconorm.
Jiyya tare da miyagun ƙwayoyi yana faruwa a cikin matakai da yawa. A matakin farko, ana daukar kwamfutar hannu guda 1 na kwayoyi yau da kullun. Jiyya bisa ga wannan tsarin yana ɗaukar kwanaki 14. A nan gaba, kashi yana ƙarƙashin daidaitawa la'akari da yanayin mai haƙuri da alamu na sukari a cikin jininsa.
Lokacin maye gurbin maganin, haƙuri yana ɗaukar allunan 1-2 na miyagun ƙwayoyi. Matsakaicin yiwuwar amfani yayin wannan rana 5 Allunan.
Marasa lafiya na musamman da kuma Jagorori
An haramta wannan maganin ga mata masu juna biyu. Hakanan ba za a yarda a sha maganin ba yayin shirin daukar ciki.
Bai kamata a shawo kan ƙwayar cuta ta hanyar lactate mata ba, tunda Metformin yana ratsa jiki cikin madara kuma yana iya cutar lafiyar jariri. A cikin waɗannan halayen, ana bada shawarar maye gurbin magani tare da maganin insulin.
Ba'a bada shawarar maganin ba ga tsofaffi marasa lafiya waɗanda shekarunsu ya wuce 60. Haɗe tare da manyan lodi, Gluconorm na iya haifar da lactic acidosis a cikin wannan rukuni na mutane.
Magungunan na buƙatar kulawa da hankali ta hanyar marasa lafiya da ke fama da:
- kasawar rashin haihuwa;
- zazzabi;
- cututtukan thyroid.
Don magani, ana ba da umarnin musamman da yawa:
- a lokacin jiyya, kulawa akai-akai na matakan glucose na jini ya zama dole duka a kan komai a ciki da bayan abinci;
- hadin gwiwa magani da barasa an haramta;
- wajibi ne don maye gurbin maganin tare da maganin insulin idan mai haƙuri yana da raunin, cututtuka, zazzabi, ƙonewa, ayyukan da suka gabata;
- Kwanaki 2 kafin gabatarwar wani abu mai kunshe-kunshe da ke dauke da aidin a jikin mai haƙuri, ya zama dole a daina shan maganin (bayan kwanaki 2, sai a sake dawo da kashi);
- haɗin gwiwa na Gluconorm tare da ethanol suna tsokani cutar rashin ƙarfi, hakan kuma yana faruwa yayin azumi da shan magungunan anti-mai kumburi da nau'in steroid;
- miyagun ƙwayoyi suna shafar ikon mai haƙuri na fitar da mota (dole ne ku guji tafiya da mota yayin magani tare da miyagun ƙwayoyi)
Side effects da yawan abin sama da ya kamata
A kan aiwatar da magani tare da magani, mai haƙuri na iya fuskantar sakamako masu illa:
- rage yawan glucose na jini (hypoglycemia);
- rage cin abinci;
- leukopenia;
- farin ciki
; - itching a kan fata;
- lactic acidosis;
- tashin zuciya tare da amai;
- thrombocytopenia;
- gajiya
- urticaria;
- gazawar numfashi tare da zazzabi a fuska da tachycardia, a matsayin martani ga yawan shan barasa;
- ciwon ciki
- anemia
- ciwon kai;
- zazzabi;
- rage ji na ƙwarai;
- bayyanar burbushi na furotin a cikin fitsari;
- jaundice
- hepatitis a cikin lokuta masu wuya.
;Za a iya bayyana adadin yawan ƙwayar cutar ta azaman:
- lactic acidosis;
- yawan haila.
Lactic acidosis yana tsokani jijiyar wuya, amai, da zafin ciki. Alamomin cutar na buƙatar dakatar da magani cikin hanzari da kuma sanya haƙuri a cikin asibiti. Mafi kyawun zaɓi mafi kyawun magani shine tsarkakewar jini na wani lokaci (hemodialysis).
Glibenclamide na iya haifar da hypoglycemia a cikin haƙuri. Lokacin da ya faru da narkewa, ciwon kai. Hakanan an lura: pallor, rashin daidaituwa ta hanyar aiki, gumi, asarar sani.
Hypeglycemia a cikin tsari mai sauƙi da matsakaici an cire shi ta hanyar ɗaukar maganin sukari ga marasa lafiya. A cikin manyan lokuta, ana allurar dashi tare da maganin 40 na glucose. An gabatar da gabatarwar ne a cikin hanji da jijiyoyin zuciya.
Hadin gwiwar Magunguna da Analogs
Abubuwa masu zuwa na hulɗa da wasu magunguna halayen magani ne:
- ethanol da gluconorm tare suna haifar da lactic acidosis;
- magungunan cationic (Vancomycin, Morphine, Quinine, Amiloride) suna kara yawan Metformin da kashi 60%;
- barbiturates, kamar Clonidine, furosemide,
Danazole, Morphine, salhi lithium, estrogens, Baclafen, Glucagon, hormones thyroid, Phenytoin, Epinephrine, Chlortalidone, nicotinic acid, Triamteren, Acetazolamide yana rage tasirin maganin; - Cimetidine, hypoglycemic jamiái, Tetracycline, Ethionamide, Guanethidine, fibrates, antifungals, enalapril, Theophylline, Cyclophosphamide, salicitates, Pentoxifylline, Pyridoxine, Reserpine, magungunan anabolic steroid sun inganta maganin antidiabetic;
- alli chloride tare da sinadarin ammonium chloride, da kuma sinadarin ascorbic acid, suna inganta tasirin maganin;
- Furosemide yana shafar maida hankali na metformin a cikin shugabanci na karuwa da kashi 22%.
Danazole, Morphine, salhi lithium, estrogens, Baclafen, Glucagon, hormones thyroid, Phenytoin, Epinephrine, Chlortalidone, nicotinic acid, Triamteren, Acetazolamide yana rage tasirin maganin;Daga cikin manyan maganganun magungunan sune:
- Forcearfin Metglib;
- Glibomet;
- Glucophage;
- Glucovans;
- Metglib;
- Bagomet Plus.
Abubuwan bidiyo game da rage yawan sukari na jini a cikin nau'in ciwon sukari na 2:
Ra'ayoyin masu haƙuri
Yawancin bita da yawa game da magungunan Gluconorm sun ƙunshi mafi kyawun amsawa ga shan magungunan, duk da haka, an ambaci sakamako masu illa, a cikin abin da tashin zuciya da ciwon kai sun fi haɗuwa da su, wanda ake kawar dashi ta hanyar daidaitawa na kashi.
Magungunan suna da kyau, yana rage sukari da kyau. Abin mamaki, ban sami sakamako masu illa ba waɗanda yawanci ana rubuta su ne game da. Farashin mai araha. Ina yin oda Gluconorm akan tsarin cigaba.
Svetlana, shekara 60
Na kasance ina fama da ciwon sukari irin na 2 shekaru da yawa. The halartar likita wajabta Gluconorm. Da farko, akwai sakamako masu illa: sau da yawa ba shi da lafiya, akwai rashin jin daɗi. Amma a nan gaba mun daidaita kashi, kuma komai ya wuce. Kayan aiki yana da tasiri idan kun hada abubuwan ci da abinci.
Tatyana, shekara 51
Gluconorm ya dogara gaba daya. A halin da nake ciki, Na taimaka don kara daidaita nauyi. Magungunan na rage yawan ci. Daga cikin minuses, zan bayyana sakamako masu illa. Da yawa daga cikinsu. A wani lokaci, kai na ba shi da lafiya.
Hauwa'u, shekara 43
Ba haka ba da daɗewa ba, masanin ilimin endocrinologist yayi wani ciwo mai ban sha'awa - nau'in ciwon sukari na 2. An wajabta gluconorm don gyara sukarin jini. Gaba ɗaya farin ciki tare da jiyya. Tare da sukari mai yawa, ƙwayar za ta iya rage matakin zuwa 6 mmol / L. Akwai wasu sakamako masu illa, amma an cire su. Ana buƙatar rage cin abinci.
Anatoly, 55 years old
Farashin gluconorm a yankuna daban-daban na kasar yana da bambance-bambance. Matsakaicin matsakaici a ƙasar shine 212 rubles. Matsakaicin farashin magungunan shine 130-294 rubles.
