A cikin lura da ciwon sukari, ana amfani da nau'ikan kwayoyi daban-daban. Sun bambanta a cikin tsarin da tsarin aikace-aikace.
Yawancin masu ciwon sukari suna buƙatar insulin don daidaita lafiyar su. Ofaya daga cikin nau'ikansa da aka yi amfani dashi azaman allura shine insulin Glargin.
Babban bayani
Wannan magani yana cikin rukunin insulin. Sunan kasuwancinsa shine Lantus. Ana amfani da wakili don kula da ciwon sukari na mellitus na insulin. Akwai shi azaman allura. Ruwan ba shi da launi kuma kusan zai bayyana.
Insulin Glargin alama ce ta insulin ɗan adam ta hanyar sinadarai. Bambanta cikin dogon aiki. Magungunan yana taimakawa rage yawan glucose a cikin jinin mai haƙuri.
Babban kayan abun da ke ciki shine Glargin insulin.
Baya ga shi, maganin ya hada da:
- glycerol;
- zinc chloride;
- metacresol;
- hydrochloric acid;
- sodium hydroxide;
- ruwa.
An ba da izinin amfani da maganin kawai tare da izinin gwani kuma a cikin sashi ɗin da aka wajabta masa, don hana rikitarwa.
Kayan magunguna
Babban tasirin wannan magani shine raguwa a cikin matakan glucose. Wannan na faruwa ne ta hanyar haɗuwa tsakaninsa da masu karɓar insulin. Verya'idar aiki iri ɗaya mai kama da halin ɗan adam.
A ƙarƙashin tasirin ƙwayar, ana inganta metabolism metabolism, yayin da ƙwararren yanki ya fara cinye shi sosai.
Bugu da ƙari, Glargin yana hana samar da glucose a cikin hanta. A karkashin tasirin sa, an samar da tsarin samar da furotin. Tsarin lipolysis, akasin haka, yana rage gudu.
Bayan shigar azzakari cikin farji na maganin ƙwaƙwalwa a cikin jiki, an keɓe shi, an kirkiro microprecipitate. Abubuwan da ke aiki suna mai da hankali sosai a cikin su, wanda a hankali aka sake shi. Wannan yana ba da gudummawa ga tsawon lokacin ƙwayoyi da kwanciyar hankali, ba tare da canje-canje masu ƙarfi ba.
Ayyukan Glargin yana farawa awa daya bayan allura. Ya ci gaba har tsawon kwana ɗaya.
Alamu, hanyar gudanarwa, allurai
Don ingantaccen magani, umarnin yakamata ayi amfani da samfurin. Dokokin shigar da likitan mata ne ke yin bayanin su.
An wajabta insulin Glargin ne kawai idan akwai dalili. Amfani da shi wajibi ne don nau'in insulin-da ya dogara da masu cutar sikila - wannan yana nuna cewa wannan cutar shine dalilin sanya shi.
Koyaya, wannan magani ba da shawarar kowa bane - gwani yakamata yayi nazarin hoton asibiti na cutar a kowane yanayi.
An ba da izinin amfani dashi ga masu ciwon sukari na nau'in farko da na biyu. A cikin nau'in cutar ta farko, ana amfani da maganin a matsayin babban magani. A wata hanyar, za'a iya ba da Glargin duka biyu ta hanyar monotherapy kuma a hade tare da wasu kwayoyi.
Sashi koyaushe ana kirga daban. Wannan ya shafi nauyin mai haƙuri, shekarunsa, amma mafi mahimmanci al'amari shine halayen cutar. A yayin jiyya, ana yin gwaji na jini lokaci-lokaci don fahimtar yadda miyagun ƙwayoyi ke aiki, da rage ko ƙara yawan a cikin lokaci.
Ana amfani da maganin a cikin hanyar injections, wanda yakamata a yi a ƙasa. Mitar allura tana sau daya a rana. Dangane da umarnin, yakamata ayi su a kusan lokaci guda - wannan yana tabbatar da inganci da rashin halayen halayen. An sanya allurar a kafaɗa, cinya ko cikin ƙoshin kitse na ciki. Don hana halayen masu illa, madadin wuraren gudanarwa.
Koyarwar bidiyo na Syringe-pen akan aikin insulin:
Contraindications da gazawa
Yin amfani da kowane magani yakamata ya yi hankali saboda gaskiyar cewa dukansu suna da contraindications. Yin amfani da kwayoyi ba tare da la’akari da contraindications da ƙuntatawa na iya haifar da rikitarwa ba.
Wannan maganin yana da ƙananan contraindications. Waɗannan sun haɗa da rashin haƙuri ɗaya na abubuwan haɗin, saboda wanda halayen rashin lafiyan zai iya faruwa.
Wani batun yayin amfani da wannan magani ya kamata a zubar dashi shine shekarun marasa lafiya basu wuce shekaru 6 ba. Dangane da yara, ba a bincika tasirin maganin ba, don haka babu cikakken bayani game da yiwuwa da amincin gudanarwarsa.
Iyakokin sun hada da:
- Matsaloli a cikin aikin kodan. Tare da wannan cin zarafin, ana iya rage metabolism metabolism. Wannan yana nufin cewa mara lafiya zai buƙaci ƙarancin magani don daidaita glucose jini.
- Tsufa (sama da shekaru 65). A cikin marasa lafiya a wannan zamani, aikin gabobin ciki, gami da kodan, sun lalace. Sabili da haka, zasu iya buƙatar ragewa a cikin maganin.
Iyakokin suna nuna takaicin likitan lokacin da yake rubuta magani. Idan akwai, ana iya bada shawarar magunguna, amma bayan tabbaci ne kawai.
Haihuwa da lactation
Babu cikakken bincike da aka gudanar game da amfani da miyagun ƙwayoyi Insulin glargine yayin haihuwar yara. Sakamakon wasu gwaje-gwajen yana nuna ɗan ƙaramin tasirin abu mai aiki a lokacin gestation da ci gaban tayin.
Saboda haka, ba a ba da shawarar yin amfani da wannan kayan aikin don maganin mata masu juna biyu. Ana iya tsara shi idan amfanin magani ga uwa ya fi haɗarin jariri.
A lokaci guda, kulawa da hankali a likita wajibi ne, tun lokacin daukar ciki matakin matakan sukari na jinin mai haƙuri na iya bambanta dangane da tsawon lokacin. Yakamata likitocin suyi nazari kan yawan sukari don daidaita maganin.
Tare da lactation, wannan magani kuma an wajabta shi azaman dole. Ba a kafa yiwuwar insulin shiga cikin madara ba.
Koyaya, ana amfani da wannan kayan amintaccen, tunda yana da yanayin furotin, sabili da haka, bazai cutar da jariri ba. Amma lokacin amfani da ita tare da mahaifiyar masu shayarwa, kuna buƙatar zaɓar madaidaicin kashi, kuma ku bi shawarwarin dangane da abincin.
Side effects da yawan abin sama da ya kamata
Ko da lokacin rubuta likita da likita, ba za ku iya tabbata cewa amfani da shi zai yi ba tare da matsaloli ba. Duk da bin umarnin, wasu lokuta kwayoyi suna da sakamako wanda ba a iya faɗi ba, wanda ke da alaƙa da halayen mutum. Saboda haka, sakamako masu illa suna faruwa.
Lokacin amfani da miyagun ƙwayoyi, matsaloli na iya tasowa kamar:
- Hypoglycemia. Wannan sabon abu yana faruwa tare da wuce haddi na insulin a cikin jiki. Yawancin lokaci, bayyanar tasa tana da alaƙa da zaɓin magani mara kyau, amma wani lokacin dalilai sune halayen jiki. Irin wannan cin zarafi yana da haɗari sosai, tunda yana shafar aikin mai juyayi. Tare da matsanancin rashin ƙarfi da rashin taimako, mai haƙuri na iya mutuwa. Wannan karkacewar ana nuna shi ta hanyar bayyanar cututtuka irin su asarar hankali, ɓarna, daskararru, da bushewa.
- Rashin gani. Tare da maganin insulin, ana lura da tsauraran kwatsam a cikin adadin glucose, wani lokacin, wanda zai haifar da retinopathy. Mai haƙuri na iya zama wahalar hangen nesa, har zuwa makanta.
- Lipodystrophy. Abin da ake kira take hakki a cikin aiwatar da rage amfani da kayan magani. Ana iya magance wannan cutar tare da taimakon canzawar kullun wuraren allurar.
- Cutar Jiki. Idan an gudanar da gwaje-gwajen da suka wajaba don maganin ƙwayar cutar kafin amfani da Glargin, irin waɗannan halayen suna faruwa da wuya kuma ba sa bambanta cikin ƙarfi. Mafi bayyanar halayyar a wannan yanayin: rashes na fata, jan launi na fata da itching a wurin allurar.
Idan kun sami irin waɗannan sifofin, ba tare da la'akari da ƙarfin su ba, kuna buƙatar tuntuɓi likita. A wasu halaye, zaku iya kawar da su ta hanyar sauya kashi na maganin. Kuma wani lokacin ana buƙatar canjin magani na gaggawa.
Yarda da takardar likita na hana mummunan tasirin da ke tattare da yawan shan ruwa. Amma wani lokacin wannan baya taimakawa. Idan akwai yawan abin sama da ya kamata, yawanci yawan jini yana faruwa. Wayar ta ya dogara da tsananin cutar. Wani lokaci zaku iya dakatar da harin ta hanyar cin abinci mai narkewa mai narkewa a jiki. Tare da mummunan hari, taimakon likita ya zama dole.
Haɗin kai tare da wasu abubuwa, analogues
Lokacin da mutum yayi wasu maganganun banda cutar sikari, to akwai bukatar gudanar da mulki na lokaci guda na magunguna daban-daban. Irin waɗannan haɗakarwa koyaushe basu da haɗari - wannan wani ɓangare ne dalilin da yasa ba'a bada shawarar yin magungunan kai ba.
Lokacin ɗaukar insulin na Glargin, yin taka tsantsan shima lallai ne, tunda yin amfani da shi a lokaci ɗaya tare da wasu kwayoyi na iya haifar da rikitarwa. Sabili da haka, likita ya kamata ya lura da duk magungunan da mai haƙuri ke amfani da shi.
Hadarin shine cewa shan wasu magunguna na iya kara tasirin hodar. Wannan yana haifar da tasirin sakamako akan jiki kuma yana haifar da haɗarin hauhawar jini.
Wadannan magungunan sun hada da:
- wakilai na hypoglycemic don gudanarwa na ciki;
- Masu hana ATP;
- salicylates;
- fibrates;
- maganin rigakafi na asalin sulfanilamide;
- kwayoyin hana kwayoyi (monoamine oxidase inhibitors).
Yin amfani da waɗannan magunguna a lokaci guda tare da insulin Glargin an yarda, amma ya zama dole don rage adadin abubuwan da ake sarrafawa.
Lokacin amfani da wasu kwayoyi, za a lura da rauni na wannan maganin. Sakamakon yana raguwa a cikin ingancin sarrafawa game da tattarawar glucose.
Daga cikin wadannan magungunan akwai:
- estrogens;
- kamuwa da cuta;
- glucocorticosteroids;
- maganin tari (wasu);
- cututtukan mahaifa.
Idan waɗannan magungunan ba za a iya soke su ba, to don ingantaccen magani kana buƙatar ƙara yawan adadin insulin glargine.
Mafi haɗarin haɗuwa sune zasu iya haifar da amsawar jiki. Lokacin amfani da miyagun ƙwayoyi a tambaya tare da beta-blockers, Pentamidine, Clonidine ko barasa, sakamakon shi na iya raunanawa da haɓaka. Sabili da haka, ana buƙatar kulawa ta musamman tare da waɗannan kwayoyi da abubuwa.
Kwatanta halayen insulin Lantus da Levemir:
Wasu lokuta ya zama dole don maye gurbin Glargin tare da wasu kwayoyi. Yawancin lokaci dalilin hakan shine rashin jituwa ga wannan magani, amma ana kuma kimanta farashin magani a matsayin muhimmin mahimmanci.
Kuna iya maye gurbin shi da irin magungunan analogous kamar Lantus (farashi daga 690.00 rubles), Lantus SoloStar (daga 690.00 rubles), Tujeo SoloStar (daga 951.00 rubles)
Yakamata likitan ya maye gurbin maganin tare da analog dinsa bayan gwajin. An hana yin wannan da kanka.