Baeta na miyagun ƙwayoyi yana da mallakin hypoglycemic kuma ana amfani dashi yayin maganin nau'in ciwon sukari na 2 na ciwon sukari. Wannan kayan aikin shine exenatide, wanda aka ɗauka amino acid amidopeptide.
Magungunan yana inganta ɓoyewar ƙwayar suga mai narkewa kuma yana taimakawa wajen sarrafa glycemia. A lokaci guda, yana rage jinkirin narkewar ciki kuma yana ƙarfafa aikin beta sel na pancreas.
Wannan labarin zai taimaka maka fahimtar cikin wane lokuta kake buƙatar ɗaukar miyagun ƙwayoyi, kuma a cikin abin da zai iya cutar da mai haƙuri da ciwon sukari.
Janar halaye na miyagun ƙwayoyi
Maganin Baeta shine mafita wanda ba a iya tanadar wa jigilar ɗan adam ba. Abubuwan da ke aiki da miyagun ƙwayoyi shine exenatide, yana kuma ƙunshi ƙananan adadin sodium acetate trihydrate, metacresol, mannitol, acetic acid, distilled ruwa. Sun saki maganin a cikin nau'ikan ampoules (250 mg), kowannensu yana da takamaiman sirinji na musamman tare da ƙarar 1.2 da 2.4 ml.
Marasa lafiya shan wannan magani lura da rage a cikin sukari jini saboda wannan inji aikin:
- Byeta yana haɓaka sakin insulin daga parenchyma tare da haɓaka yawan glucose a cikin jinin mutum.
- Insulin insulin yana dakatarwa a daidai lokacin da ake samun raguwar matakan sukari.
- Mataki na karshe shine a tsayar da glucose dinka.
A cikin mutanen da ke fama da nau'in na biyu na ciwon sukari, yin amfani da miyagun ƙwayoyi yana haifar da irin waɗannan canje-canje:
- Yin rigakafin yawan glucagon samarwa, wanda ke hana insulin.
- Hanawa na ciki na ciki.
- Rage abinci.
Lokacin da aka sarrafa magani a ƙarƙashin ƙasa, abu mai aiki ya fara aiki nan da nan kuma ya isa mafi girman tasiri bayan sa'o'i biyu.
Tasirin miyagun ƙwayoyi an dakatar da shi kawai bayan kwana ɗaya.
Umarnin don amfani da miyagun ƙwayoyi
Likitocin da ke halartar za su iya ba da magani ne, a kowane hali ya kamata ku ba ku magani kai. Bayan samun magungunan Baeta, ya kamata a bincika umarnin yin amfani da shi sosai.
Nunin amfani da wannan magani shine ciwon sukari na 2 wanda ke da maganin ƙwayar cuta mai ƙwayar cuta ko ƙwaƙƙwaran magani. Ana amfani dashi lokacin da ba zai yiwu ba a sarrafa sarrafa yadda yakamata. Za'a iya amfani da maganin a hade tare da irin waɗannan hanyoyin:
- Metformin;
- Thiazolidinedione;
- Abubuwan da suka samo asali na sulfonylurea;
- haɗuwa da metformin, sulfonylurea;
- hadarin metformin da thiazolidinedione.
Maganin maganin shine 5 μg sau biyu a rana don awa daya kafin a ɗauki babban kwano. An saka allurar cikin yatsun hannu, cinya ko ciki. Bayan wata daya na cin nasara, maganin yana karawa zuwa 10 mcg sau biyu a rana. Idan ana amfani da miyagun ƙwayoyi tare da abubuwan da aka samo asali na sulfonylurea, kashi na ƙarshen dole ne a rage shi don guje wa yanayin haƙuri.
Wadannan sharudda game da gudanar da maganin ya kamata a lura kuma:
- ba za a iya gudanar da shi bayan cin abinci ba;
- ba a ke so a yi allura ko a ciki;
- idan mafita yana da gajimare da canza launi, zai fi kyau amfani da shi;
- idan an samo barbashi a cikin mafita, dole ne a soke gwamnatin miyagun ƙwayoyi;
- yayin Bayeta far, samar da maganin rigakafi yana yiwuwa.
Dole ne a kiyaye miyagun ƙwayoyi a wuri mai kariya daga haske da ƙananan yara. Ya kamata a lura da zafin jiki na ajiya a cikin kewayon daga digiri 2 zuwa 8, saboda haka ya fi kyau a ajiye maganin a firiji, amma kada a daskare shi.
Rayuwar shiryayyen samfurin shine shekaru 2, kuma mafita a cikin sirinji shine wata 1 a zazzabi wanda bai wuce 25 ba.
Kudin maganin da kuma sake dubawa
Za'a iya siye magungunan Baeta a kowane kantin magani ko sanya oda a cikin kantin kan layi. Ya kamata a sani cewa ana sayar da maganin ne kawai ta hanyar takardar sayan magani. Tun da wanda ya ƙera wannan samfurin Sweden ne, gwargwadon farashin sa ya yi yawa.
Sabili da haka, ba kowane talaka bane mai kamuwa da cutar sankarau zai iya siyan irin wannan magani. Farashi ya bambanta da irin yadda aka saki kuɗi:
- Alkalami mai sirinji na milimita 1.2 - daga 4246 zuwa 6398 rubles;
- Alkalar sirinji 2.4 ml - daga 5301 zuwa 8430 rubles.
Kwanan nan an gudanar da bincike na tallan tallace-tallace, wanda aka zaɓi halartar marasa lafiya waɗanda suka ɗauki wannan magani da kansu. Magana game da maganin Bayeta, wanda sake dubawa ya nuna kasancewar sakamakon mummunan sakamako masu zuwa:
- Rushewar tsarin juyayi: gajiya, murdiya ko rashin dandano.
- Canza yanayin rayuwa da rage cin abinci: asarar nauyi, rashin ruwa a jiki saboda amai.
- A mafi yawan lokuta da ke faruwa a lokacin anaphylactic dauki.
- Rashin daidaituwa da pathologies na narkewa mai narkewa: karuwar haɓakar gas, maƙarƙashiya, matsanancin ƙwayar cuta (wani lokacin).
- Canje-canje a cikin urination: lalacewar aikin na renal, ƙarancin matakan creatinine, gazawar renal ko kuma ƙarfinta.
- Abubuwan da suka shafi ƙwayar fata: alopecia (asarar gashi), itching, urticaria, angioedema, maculopapular rashes.
Tabbas, maɓallin mara kyau shine babban farashin ƙwayoyi, saboda wannan dalili ne cewa yawancin marasa lafiya da ciwon sukari suna barin sake duba su akan Intanet. Amma, duk da wannan, maganin da gaske yana rage matakin glucose a cikin jinin mai haƙuri kuma yana taimakawa wajen yaƙi da nauyi.
Haka kuma, saboda irin tasirin da yake da shi na warkewarta, ba ya haifar da hauhawar cututtukan jini.
Contraindications da m halayen
A wasu halaye, shan miyagun ƙwayoyi ya zama ba zai yiwu ba saboda kasancewar contraindications ga mai haƙuri. Zai iya zama:
- mai ciwon sukari ketoacidosis - wani cin zarafi a cikin metabolism na carbohydrates;
- nau'in insulin-dogara da ciwon sukari;
- gazawar renal tare da CC kasa da 30 ml / min;
- pathology na narkewa kamar ba tare da gastroparesis;
- rashin haƙuri a cikin abubuwan da ke cikin miyagun ƙwayoyi;
- yara da matasa da ke ƙasa da shekara 18;
- lokacin haihuwar yaro da shayarwa.
Tare da yin amfani da shi ba da kyau ko don wasu dalilai, halayen m suna faruwa, an bayyana:
- rashin lafiyan, wato urticaria, fatar fata, da itching;
- rikicewar narkewa - tashin zuciya, amai, flatulence, zawo, maƙarƙashiya, rage jiki da ci;
- rikice-rikice na tsarin juyayi, watau nutsuwa, farin ciki, ciwon kai;
- gazawar koda / hanta;
- karuwa a lokacin coagulation;
- ci gaban hypoglycemia, pancreatitis, hyperhidrosis;
- karuwa a cikin kwayoyin halittar ruwa.
A yanayin halayen da ba su da kyau, ƙwararren halartar na iya daidaita tsarin kula da wannan magani tare da soke amfani da shi gaba ɗaya.
Analogues na miyagun ƙwayoyi
A cikin yanayin yayin da ba za a iya gudanar da haƙuri irin waɗannan mafita ba ko kuma ya ji raunin da ba shi da kyau, likitan halartar na iya sauya dabarar magani. Wannan yana faruwa ne ta manyan hanyoyi guda biyu - ta hanyar canza sashi na miyagun ƙwayoyi ko ta hanyar barin shi gaba ɗaya. A lamari na biyu, wajibi ne don zaɓar magungunan analog waɗanda zasu sami tasirin warkewa iri ɗaya kuma ba cutar cutar da masu cutar siga ba.
Don haka, Baeta bashi da irin wannan hanyar. Kamfanonin AstraZeneca da Bristol-Myers Squibb Co (BMS) ne kawai ke samar da analogues na 100% na wannan magani (kwayoyin). Akwai nau'ikan magunguna guda biyu a kasuwar magunguna na Rasha, waɗanda suke daidai da tasirin warkewarsu. Wadannan sun hada da:
- Victoza magani ne, kamar Baeta, ƙarancin ƙwaƙwalwa ne. Hakanan ana samar da miyagun ƙwayoyi a cikin nau'in sirinji na ƙwayar cuta don infusions na subcutaneous a cikin nau'in ciwon sukari na 2. Amfani da miyagun ƙwayoyi na yau da kullun yana taimakawa rage ƙimar haemoglobin ta glycated zuwa 1.8% kuma rasa ƙarin kilogiram 4-5 a cikin shekarar far. Ya kamata a lura cewa likita ne kawai zai iya ƙayyade dacewa da takamaiman magani. Matsakaicin matsakaici (maganin sirinji 2 na 3 ml) shine 10,300 rubles.
- Januvia wani abin birgewa ne wanda ke rage sukari jini a cikin jiyya na ciwon sukari na 2. Akwai shi a cikin kwamfutar hannu. Matsakaicin farashin magani (raka'a 28, 100 MG) shine 1672 rubles, wanda shine mafi arha a tsakanin magungunan da ake tambaya. Amma tambayar wanne magani zai fi dacewa a ɗauka ya kasance a cikin kwarewar likita.
Sabili da haka, magungunan Bayeta ingantaccen wakili ne na hana haihuwa. Sakamakon warkewarta yana da wasu fasalulluka waɗanda ke taimakawa cimma cikakken ikon sarrafa glycemic. Koyaya, ba za'a iya amfani da maganin a wasu yanayi ba, kuma yana iya haifar da sakamako mara kyau.
Sabili da haka, magungunan kai ba shi da daraja. Wajibi ne a gudanar da balaguro zuwa likita wanda ya tantance bukatar amfani da miyagun ƙwayoyi, la'akari da halayen jikin kowane mai haƙuri. Tare da matakan da suka dace da bin duk ka'idodi don gabatarwar mafita, zaku iya rage sukari zuwa matakan al'ada kuma ku kawar da alamun cututtukan hawan jini. Bidiyo a cikin wannan labarin yayi magana game da magunguna masu ciwon sukari.
