Abubuwan da ke tattare da cutar sankarau suna da yawa-gefe da bambanci.
Sun ƙunshi rikice-rikice na nau'ikan metabolism na nama na jiki, ciki har da mai, bayyanar wanda zai iya kasancewa duka atrophy na adipose nama, da kuma sake fasalin saƙo - lipohypertrophy.
Ya bayyana a fili ta yanayin mai ƙyalli na kitse, amma yana rinjayar canje-canje a wasu sassan jikin.
Menene wannan
Manufar lipodystrophy (lalata degeneration) ta hada da mafi yawancin bambance-bambancen asali da kuma bayyanar cututtuka na rayuwa a cikin nama na adipose, wanda yake aiki a matsayin sifofin da babu makawa game da wanzuwar kowane ƙwayar halitta.
Don haka, kasancewar kitse mai tsayayye yake sanya sutturar ƙwayar hanta a cikin ƙwaƙƙwaran ƙwaƙwalwar haɗin jikinta yana ba da gudummawa ga kwanciyar hankali na zazzabi a cikin ƙwayar, yayin da a lokaci guda gyara shi a wurin da ya dace (yana hana yiwuwar faduwa).
Amma koda koda sashin jiki bashi da kyan gani wanda yake gani, to yana wanzuwa a matakin kwayoyin - ba kwayar sel guda da zata iya yin ba tare da hada kalar lipid din ba.
Babban ra'ayin lipoatrophy yana da ikon ba da jikin mai motsa jiki-mai gina jiki tare da ƙararrakin taimako mai sauƙi. Amma tare da ɗaya “amma”: har ma da cikakkiyar rashi cutarfin kitse, har yanzu yana da. Tare da lipoatrophy, kasancewar ba zai yiwu ba a cikin manufa, duk da ƙirƙirar yanayi mai kyau na abinci da kuma bayar da wadataccen kayan abinci da abubuwan sha waɗanda ke taimakawa wajen tara mai (giya, cream, mai, muffins).
Distinwararren fasalin lipodystrophy daga dystrophy shine haɓakar al'ada na ƙwayar tsoka ba tare da alamun hanawa ba.
Lipohypertrophic dystrophy shine yanayin yanki mai ƙyalli mai rauni, daidai da akasi game da abin da ke sama.
Samfurin samfurin (biopsy) wanda aka samu a microsample da aka samu ta hanyar wuce wani sashi mai mahimmanci daga kwayoyin halitta) yana nuna hoto ba wai kawai kasancewar ƙarancin tsopose nama a cikin ƙwayar subcutaneous ba, har ma da yalwar ƙwayar cuta, cibiyar sadarwar-mara jijiyoyin jiki da ke girma a ciki, wanda ke nuna matsala a cikin tafiyar matakai na rayuwa da tsinkayar rai Tsarin sashi har zuwa zurfin lalata.
Bidiyo game da etiology na lipodystrophy:
Iri da fasali na Pathology
Menene zaɓuɓɓukan da aka tattauna a sama - nau'in narkar da mai?
A farkon lamari, akwai rashin tsaro na sashin jiki (tsoka, fata, hanta) daga sakamakon abubuwan illa:
- waje (zazzabi sama ko ƙarami, daga rauni);
- ciki (canje-canje a cikin abun da ke gudana jini a cikin tsari na wani karamin abu ko abun ciki na glucose, gubobi da sauran abubuwan dake ciki, ko kasancewar kamuwa da cuta a ciki).
Na biyu yana shaidar zurfin zurfin yanki ko yanki na gabobin daga tsarin maƙwabta, wanda, a yanayi mai kyau, zai haifar da ƙirƙirar ƙwarin gwiwa mai ƙarfi, a cikin mafi ƙarancin amfani - mutuwar nama mai aiki tare da maye gurbinsa da ƙura.
Dalilin bayyanar
Don abin da ya faru da ci gaban lipodystrophy, akwai dalilai:
- sharadin ta gado (hereditally fix, ko a cikin haihuwa);
- ɓata ayyukan rayuwa a cikin jiki (wanda aka samo).
Kashi na farko ya hada da yanayi wanda:
- lipodystrophy na sashi na dangi;
- Berardinelli-Seip syndrome.
Na biyu yafi yawa, ya hada da lipodystrophy:
- m (ya zama ruwan dare, yana da alaƙa da sassan jikin mutum), ɓangarorin cutar cututtukan Barraquer-Simons;
- na kowa (wanda ya ƙunshi jiki baki ɗaya);
- infantile (halayyar yara) sashin tsakiya na centrifugal;
- zolo-dimbin yawa atrophy na adipose nama (Ferreira-Markish syndrome);
- insulin-sharadi;
- HIV hade
- sauran nau'ikan tare da yanayin dabi'ar aiwatarwa.
Lipodystrophy a cikin ciwon sukari
Halin yana da alaƙa da haɗuwa da jikin insulin, mai alhakin:
- musayar ba kawai carbohydrates, har ma da mai da furotin;
- tsari na tafiyar matakai da haɓaka kyallen takarda (rabuwa tare da samuwar ingantaccen tsari, wanda ke tabbatar da daidaiton aikinsu);
- Hanyar karatun kwayoyin halitta, wanda ba tare da yin amfani da DNA ba zai yiwu ba.
A gaban ciwon sukari mellitus, ciwon insulin jurewar mahaifa yana faruwa - ƙwararren ƙwayar nama a cikin nau'i na watsi da hormone ko kuma gurguwar magana a kanta.
Dangane da tasirin sa akan ƙwayar tsose tare da injections na yau da kullun, wannan yana nufin faruwarsa ta ruɗuwa biyu zuwa ga hyper- da hypotrophy.
A zahiri, yayi kama da fitowar “ƙyallen” ƙarancin fata a jikin fata ko kuwa an kwatanta shi da “ramuka” - fata.
Tsarin ilimin tarihi na yankunan da aka lalace:
- ya kara dagula tsarin daukar insulin daga wadannan yankuna;
- ba ya bada damar cimma farko da ƙarshen aikin insulin a cikin ainihin lokacin da aka ƙayyade (musamman a lokuta tare da kwayoyi na tsawan matakan aiki).
Bayyanar cututtuka da kuma bayyanar
Ganin cewa mai sanadin lalacewa yana faruwa ne ta hanyar allurar ƙananan allurar insulin, ba za su iya faruwa a cikin nau'in ciwon suga na II ba (wanda ba shi da insulin).
Suna rakiyar takamaiman aikin I na ciwon suga, wanda aka nuna:
- ƙishirwa;
- ciwon sukari (yawan urination akai-akai tare da manyan fitsari);
- daɗin ɗanɗanin fitsari (wanda aka bayyana ta ƙunshin glucose).
- rashin cin abinci mara wahala;
- nauyi asara.
Lipodystrophy na gabobin ciki ba ya bayyana a waje (kawai rikicewar dabi'a ta ayyukan waɗannan gabobin ne yasa aka bincika shi). Amma dangane da fata, ba lallai bane a lura da abin da ya faru.
A cikin yaro da ke fama da ciwon sukari da ke fama da cutar kansa, ana iya lura da farawar lipodystrophy bayan wani lokaci daban daga farkon allura: daga abin da makonni ya zuwa 8 ko ma shekaru 10.
Har ila yau, mata sun fi zama muhimmi a cikin bayyanar waɗannan canje-canje na fata-karkashin ƙasa, galibi mai zaman kansa na:
- nau'in magani da aka yi amfani da shi;
- maganinsa;
- tsananin tsananin cutar;
- matakin ramawa game da metabolism metabolism.
Nau'in nau'in canje-canje iri-iri ana nuna shi ta hanyar maimaitawa (yanki, iyaka yankin allura) canji na nama, ko ana nuna su da cikakkiyar daidaituwa da daidaituwa na sutturar fat mai ƙoshin ƙasa a ƙarƙashin dukkan jikin. Mai yiwuwa, bayanin su ya faru ne ta hanyar rashin isasshen matakin tsarkake magungunan, da kuma rashin bin ka'idodin allura: gabatarwar da ba a magance shi ba, shigar da barasa cikin kauri da fata.
Nau'in mai hauhawar jini (lipohypertrophy) yana bayyana ta hanyar bayyanar da bututun, yana fitowa daga kauri mai kauri wanda aka gina ta hanyar lalacewar tsopose nama tare da kwalliyar ƙwayar ƙwayar fibro-scar (duba hoto). Bayyanar da yanayin wadannan majallolin yana faruwa ne sakamakon zabin insulin akan mai mai narkewar kyallen takarda a cikin karancin sararin samaniya.
Lipodystrophy na hoto saboda allurar insulin:
Za'a iya haɗu da kasancewar lipodystrophy a cikin ciwon sukari tare da sauran alamun fata:
- xanthomatosis;
- lipoid necrobiosis;
- kiba dysplastic.
Hanyoyin jiyya
Sakamakon jahilcin dukkan dalilan da ke haifar da mummunan lalacewar mai, tasiri mai tasiri kan aiwatar da samuwar sa da haɓakarsa ba zai yuwu ba, saboda haka, hanyoyin da ake amfani da su suna ba da sakamako na ɗan gajeren lokaci.
Daga cikinsu akwai amfani da:
- abinci
- ilimin jiki;
- dabarun motsa jiki (inductothermy da duban dan tayi).
Tasirin duban dan tayi shiga zurfin cikin kyallen takarda ta 10 cm, yanayin canzawa wanda yake motsa jini, yana haifar da mafi girman yanayin jikin mai. Amfani da shi haɗe tare da aikace-aikacen maganin shafawa na hydrocortisone yana ba da gudummawa ga saurin murmurewa ga wuraren da aka zubar da su. Aikace-aikacen wadannan matakan sun bada damar hana ci gaban aiwatar da shi na tsawon watanni shida zuwa shekaru biyu.
Oƙarin hana haɓakar lipodystrophy ta hanyar dakatar da amfani da inhibitors na kariya, canza tsarin ARVT (maganin hana haihuwa), da kuma amfani da liposuction da hanyoyin tiyata na kwalliya (ta yin amfani da injections da implants) suna ba da sakamako na ɗan lokaci.
An gwada hanyoyin inganta wannan yanayin:
- hormone girma na mutum;
- testosterone
- magunguna waɗanda ke rage taro na triglycerides da cholesterol a cikin jini, kazalika da haɓaka hankalin insulin.
Wani bangare mai mahimmanci na farfaɗo shine haɓaka matakin motsa jiki da rage cin abinci (musamman, tare da yalwar abubuwan haɗin gilashi waɗanda ke ba ka damar sarrafa matakin juriya na insulin, ƙara sautin jiki da rage haɗarin zuciya da jijiyoyin bugun jini).
Yin rigakafin rikice-rikice
Sakamakon kasancewar kasala mai rikitarwa ya haifar da rikicewar cututtukan da ke haifar da su, cikakken matakan matakan hana su zama dole.
Abubuwan da aka saba dasu suna kiyaye daidaitaccen aiki na jiki da kuma bin abincin da aka ba da shawarar, kazalika da tsayayyen yawan ƙwayoyi waɗanda likitanku ya umarta a ƙarƙashin kulawa ta jiki koyaushe.
Dangane da asalin insulin yanayin, ana kula da cutar da take aiki. Hakanan wajibi ne don yin aiki da ka'idodi don allura (guji shigar da barasa a cikin raunin fata), dumama ƙwayar allurar zuwa zafin jiki.
Yin amfani da insulin musamman nau'ikan insulin mai tsafta (monocomponent da monopic) da kuma shirye-shiryen insulin mutane na musamman suma suna taimakawa wajen magance rikitarwa.
