Almubazzaranci shine daya daga cikin abubuwanda ke haifarda cututtukan jini, musamman idan aka sha giya akan komai a ciki ko kuma karancin abinci na rashin ingancinsu. Ana haifar da irin wannan sakamako ta hanyar ɗaukar abin sha mai ƙarfi bayan ɗaukar nauyin tsoka ko dogon hutu cikin abinci. Matsayin ƙayyadaddiyar rawa ana yin shi ta hanyar abubuwan da ke cikin barasa wanda ya shiga cikin jiki da bayyanar sa.
Hypoglycemia tsokani da shan magunguna sau da yawa ci gaba a kan tushen giya maye. Ethanol na iya rage mitirin glucose na jini tare da mummunan sakamako da haɗari.
Yadda barasa ke tsokanar cututtukan cututtukan zuciya
Halin ethanol a cikin jini kwalliya ce:
- Da farko dai, yana kara ayyukan insulin da allunan rage sukari.
- Tahanyar hanta, ethanol yana hana samar da glucogen - ƙarin tushen glucose.
Hanyar aikin giya mai kama da ayyukan lipids: yana narke mai, yana ƙaruwa da girman ƙwayoyin mai. Ta hanyar yaduwar ƙwayoyin membranes, glucose daga jini yana shiga cikin tantanin halitta. Lokacin da abin da ke cikin jijiyoyin jikinsu ya fadi, matsananciyar yunwar ta bayyana.
Hanyar aikin giya mai kama da ayyukan lipids: yana narke mai, yana ƙaruwa da girman ƙwayoyin mai. Ta hanyar yaduwar ƙwayoyin membranes, glucose daga jini yana shiga cikin tantanin halitta. Lokacin da abin da ke cikin jijiyoyin jikinsu ya fadi, matsananciyar yunwar ta bayyana.Bugu da ƙari, ethanol yana daidaita aikin haɓakar hormone kuma yana gurbata cikakken isasshen amsawar jiki ga canje-canje na ƙwayar plasma. Wannan shine ɗayan abubuwan da suka fi haifar da cututtukan hypoglycemia a cikin mutanen da ke shan giya, tunda hormone girma yana sarrafa glucometer.
Godiya ga "adadin kuzari" wanda kwayoyi ethanol ya ƙunshi, yana hana amfani da mai mai.
Hanyar haɓakar ƙwayar tsotsar jini
Masu ciwon sukari da ke da "ƙwarewa" na cutar sun san game da rage karfin giya. Matsayin glucose ya hau a cikin hanyoyi biyu: tare da cin abinci na carbohydrates tare da abinci da kuma ta hanyar samar da glycogen ta hanta. Rashin daidaituwa na glucose yana tallafawa matakan sukari ba ƙasa da 3.3 mmol / L ba. Idan barasa yana hana gluconeogenesis ta hanyar toshe hanta, tunanin me zai faru da jiki lokacin da ba'a fitar da glucose ba. Samun damar samun hauhawar jini ya fi yawa a cikin masu ciwon sukari da ke dogara da su, tunda daidaita kashi ɗaya don yin la’akari da mai maye bashi da sauki.
Ethanol yana haifar da hypoglycemia saboda rushewar tsarin gluconeogenesis tare da canji a cikin cytosolic rabo na NADH2 / NAD. Gudun giya a cikin hanta yana ɗaukar barasa dehydrogenase. Maganin haɗin enzyme, NAD (nicotinamide adenine dinucleotide) sashi ne mai mahimmanci na glucogenesis. Yawan shan barasa a cikin tsarin jijiyoyin jiki yana haifar da amfani da yawan aiki na NAD da kuma toshe hancin glycogen a hanta.
Babu shakka, hypoglycemia na giya yana haɓakawa da ƙasan asali na raguwar albarkatun glycogen, lokacin da ƙarfin hanta ga glucogenesis yana da matukar muhimmanci ga daidaituwar sukari. A haɗarin mutane masu shan giya koyaushe tare da rage cin abinci.
Baya ga metabolism a matakin salula, ethanol yana hana sha a cikin hanta abubuwan da ke cikin aikin glycogen (lactate, alanine, glycerin). Abinda ke cikin alanine a cikin magudanar jini shima ya fadi sakamakon hanawar shigowarsa daga tsokoki.
Cutar cutar sankara ta hypoglycemic state
Alcoholism wani abu ne na yau da kullun da ake buƙata don haɓakar cututtukan jini zuwa ɓangaren waɗanda ke fama ba tare da bincike na cutar sankara ba. Da farko, an ƙididdige irin wannan ƙididdigar ta wurin ƙazamtattun abubuwa waɗanda ke ƙunshe da ƙarancin sha mai ƙarfi. Amma bayan gwaje-gwajen da aka samu da ethanol, waɗanda aka ba da cikakkiyar lafiya masu sa kai waɗanda suka yi fama da farauta na kwana biyu ko uku kuma suka nuna irin wannan sakamakon, dole ne a canza wannan ra'ayi.
Yawancin cututtukan cututtukan ƙwayar cuta ana samun su a tsakanin masoya masu shaye-shaye waɗanda ba tare da abun ciye-ciye ba na kwana ɗaya ko biyu. Rikici yana tasowa a cikin sa'o'i 6 zuwa 24 bayan ethanol ya shiga cikin jini, don haka ba daidai bane a binciki wani hari ta ƙanshin daga bakin, binciken dakin gwaje-gwaje ya zama dole. Akwai tarihin alamun bayyanar cututtuka a cikin nau'i na yawan amai, wannan yana nuna haushi na tsarin juyayi da ciki tare da barasa, rashi mai kalori, lokacin da waɗannan abubuwan abinci waɗanda ke dauke da ethanol suka shiga ciki.
A hadarin, a matsayin mafi yawan saurin kamuwa da cututtukan shaye-shaye:
- Masu fama da cutar insulin;
- Marasa lafiya tare da cututtukan cututtukan ƙwayar ƙwayar cuta ta pituitary-adrenal;
- Yaran da suka sami damar shan giya kwatsam.
Hadarin dake faruwa na cututtukan cututtukan zuciya da kuma halin halin halin ɗimawar jiki a cikin yara na yearsan shekaru 5. Yawan mutuwa na ethanol na yara shine 3 g / kg (a cikin manya - 5-8 g / kg).
Alcohol-induced na jinin haila yawanci yakan ƙare a cikin coma. Zai yi wuya a rarrabe wannan yanayin daga guba mai sa maye.
Alcohol hypoglycemia yana halin mahimman alamu na asibiti:
- Hypothermia (a sakamakon hypoglycemia);
- Rage numfashi (tare da lactic acidosis concomitant);
- Hankalin ethanol a cikin jini yana ƙasa da al'ada a cikin maye (har zuwa 1000 mg / l);
- Matsayin sukari - har zuwa 300 mg / l (tare da gabatarwar glucagon, sakamakon ba ya canzawa);
- Rashin insulin jini ya ragu, akwai alamun ketonoturia;
- Alkohol ketoacidosis saboda tarawar lactic acid.
Gwajin hepatic yana nuna al'ada, yana yiwuwa a bincika yanayin kawai gwargwadon tarihin yawan shan barasa da aka lura a cikin anamnesis. Bayan maido da albarkatun glycogen, tsokanar giya ba ya haifar da cututtukan jini.
Hypoglycemia tare da tushen giya ya dogara da kashi-kashi: yawan wanda aka kashen ya dauka, ana tsawatar da glucogenesis. Na musamman haɗari shine jinkirta nau'in hypoglycemia. Idan da yamma ya sha mai ƙarfi na giya, rikicin na iya faruwa da dare. Saboda ƙarancin maida hankali na glycogen a cikin hanta, wannan yanayin yana da wuyar magani. Shan giya yana taimakawa wajen yin watsi da alamomin abubuwan da ke haifar da cutar sikari, don haka ba a ɗaukar matakan da suka dace don kawar da su.
Yadda za a kawar da nau'in barasa mai guba
Ba tare da bincike na kan lokaci ba da kuma kulawar da ta dace da gaggawa, ana lura da mace-mace a cikin wannan yanayin a cikin 25% na yara da 10% na wadanda suka balaga.
Gabatar da glucagon baya warware matsalar lalacewa ta hanyar maye saboda giya, tunda babu sauran glycogen da ke ciki, gami da yadda jikin ya ɗauki wannan hormone. Injections na glucose suna da tasiri don rage matakan lactate da daidaita ma'aunin acid-base. Ba kamar sashi na maganin hypoglycemia ba, mara lafiya baya buƙatar ci gaba da glucose. A cikin yara waɗanda ke da irin wannan bayyanar cututtuka, suna farawa da glucose, kuma dropper tare da maganin glucose-electrolyte ya cika shi.
A matsayin taimakon farko (idan wanda aka azabtar yana sane) an ba shi damar amfani da carbohydrates mai sauri - Sweets, ruwan 'ya'yan itace mai dadi. Relapses na hypoglycemia ana hana shi tazara adadin carbohydrates. Allunan glucose suna dauke da daidaitattun adadin carbohydrates.
Hanya mafi kyau don kawar da kwayar cutar mahaifa shine hanawa:
- Masu ciwon sukari suna buƙatar rage shan barasa.
- Barasa ba zai zama wata hanya ta rage yawan ƙwayar cuta ba.
- Tare da ingantaccen hanta, an ba shi damar cinye 50 g na vodka da cognac ko 150 MG na busassun giya (babban ma'aunin sha shine rashin sukari da ƙarancin adadin kuzari).
- Wani lokaci zaku iya shan giya - har zuwa 300 g (cutar da carbohydrates tana biya sakamakon fa'idodin yisti).
- An haramta duk abin sha mai ƙarfi mai zaki - kayan zaki da ruwan giya, giya, barasa, da sauransu. Ga mata masu juna biyu, babu wani zaɓi: an haramta shan giya bisa manufa.
- Ka tuna cewa masaniyar barasa tana nuna alamun shigowar ɗimin jini, gami da jinkirta. Gargadi game da matsalolinku ga wadanda suke wannan lokacin.
- Ya kamata a cinye abincin giya bayan cin abinci.
- Kafin tafiya barci, tabbatar cewa yin cikakken bayani don sukari kuma ku ci wani abu tare da carbohydrates.
- Lokacin yin lissafin adadin kuzari na abincin ku, la'akari da adadin kuzari na barasa: 1 g na furotin ko carbohydrates - 4 kcal, 1 g na mai - 9 kcal, 1 g na ethanol - 7 kcal.
- Kasance cikin shiri don gaskiyar cewa barasa zai haɓaka taro na triglycerides, haɓaka bayyanar da alamun bayyanar cututtukan jijiyoyi a cikin ƙwayar bugun jini.
