Glimepiride (a cikin girke-girken Latin - Glimepiride) - Wannan magani ne wanda ba'a manta dashi yau ba. Daga cikin dukkanin magungunan antidiabetic waɗanda ke wakiltar aji na magungunan sulfonylurea, wannan magani ne mai dacewa sosai. Lokacin da kwayoyin sun fara bayyana a cibiyar sadarwar kantin magani, sun kasance ɗayan magungunan mashahuri. Amma bayan gano wani sabon aji na kwayoyi (incretins), suka fara manta undeservedlyly.
Har ila yau, maganin yana da damar-cututtukan cututtukan cututtukan cututtukan ƙwayar cuta: ƙara haɓakar jijiyoyin jiki zuwa insulin ƙwayar cuta, rage samar da glucose a cikin hanta, hana ƙwanƙwasa jini, da rage matakin radicals.
Form sashi
Kamfanin masana'antar cikin gida PHARMSTANDART yana samar da Glimepiride a cikin nau'ikan allunan capsule 4:
- Launin ruwan hoda mai haske - 1 MG kowane;
- Haske kore mai haske - 2 MG kowane;
- Haske mai rawaya - 3 MG;
- Haske mai launin shuɗi - 4 MG kowace.
An kwantar da capsules a cikin murhun alummuka na inji mai kwakwalwa guda 10., An sanya faranti a cikin kunshin takarda. Adana magungunan a cikin akwatinta na asali a zazzabi na ɗakuna ba fiye da shekaru 3 ba. Ga Glimepiride, farashin a kantin magunguna na kan layi ya kasance daga 153 rubles. har zuwa 355 rub. dangane da sashi. Kasuwan magani shine magani.
Glimepiride - analogues da kwatanci
Magungunan asali, na farko, mafi yawan karatu, shine Amaril daga kamfanin Sanofi Aventis. Duk sauran magunguna, gami da glimepiride, analogues ne, kamfanonin magunguna suna samar da su bisa ga patent. Daga cikin shahararrun:
- Glimepiride (Russia);
- Diamerid (Russia);
- Diapyrid (Ukraine);
- Glimepirid Teva (Croatia);
- Glemaz (Argentina);
- Glianov (Jordan);
- Glibetik (Poland);
- Amaril M (Koriya);
- Glairi (Indiya).
Abun da ke cikin magani Glimepiride
Glimepiride wakili ne na maganin antidiabetic mai dauke da karfin rashin karfin haihuwa. Magungunan yana cikin rukunin sulfonamides, abubuwan asalin urea.
Babban kayan aiki na kwayoyi shine glimepiride. A cikin kwamfutar hannu guda, nauyinsa shine 1 zuwa 4 MG. An inganta abu mai aiki tare da abubuwan taimako: sitaci sitaci, povidone, polysorbate, microcrystalline cellulose, lactose, magnesium stearate, indigo aluminum varnish.
Pharmacology
Glimepiride magani ne na antidiabetic daga ƙungiyar sulfonylurea wanda ke aiki idan aka sha bakinsa. An tsara shi don sarrafa nau'in ciwon sukari na 2. Hanyar aikin miyagun ƙwayoyi ya dogara ne akan ƙaruwar ƙwayoyin-responsible-mai alhakin samar da insulin kwayoyin halitta. Magungunan suna haɗuwa da furotin membrane na waɗannan sel cikin sauri.
Kamar duk magunguna a cikin wannan rukunin, ƙwayar tana ƙara ƙarfin jiɓin kyallen takarda zuwa haɓakar glucose. Tana da magani da kuma karin motsa jiki. Samun insulin a ƙarƙashin rinjayar miyagun ƙwayoyi yana faruwa ne saboda ingantacciyar damar zuwa tashoshin calcium: haɓakawa da yawaitar ƙwayar alli yana inganta sakin insulin.
Daga cikin illolin da ke tattare da cutar kwayar cuta, raguwar juriya daga kwayoyi zuwa kwayar kwai da raguwar yadda ake amfani da ita a hanta. A cikin tsokoki da kitse na jiki, glucose yana ƙonewa tare da taimakon jigilar sunadarai, aikin da ke ƙaruwa sosai bayan ɗaukar magani.
Pharmacokinetics
A bioavailability na glimepiride ne 100%. Daidaici shan abinci mai gina jiki yana rage jinkirin sha kadan. Ana lura da mafi girman abubuwan plasma 2.5 sa'o'i bayan an karɓi magani a cikin narkewa. Thearancin magungunan yana ƙasa da ƙasa (8.8 L), yana ɗaure wa furotin magani gwargwadon iko (99%), tsabtace magungunan shine 48 ml / min.
Tare da sake yin amfani da allurar allura, matsakaicin rabin rayuwar shine awowi 5-8. Tare da karuwa a cikin maganin warkewa, wannan lokacin yana ƙaruwa. An cire metabolabolites ta halitta: 58% na kashi ɗaya wanda alamar isotope na rediyo tayi alama da aka samu a cikin fitsari kuma 35% a cikin feces. Rabin rayuwar samfuran lalata ne sa'o'i 3-6.
Babu bambance-bambance na asali a cikin kantin magani na glimepiride a cikin masu ciwon sukari na matasa ko balagagge, mace ko namiji. A cikin masu ciwon sukari tare da ƙarancin keɓantar da ƙwaƙwalwar ƙwayar cuta, babu wani haɗarin haɗuwa da miyagun ƙwayoyi. Sigogi na pharmacokinetic a cikin marasa lafiya 5 bayan cholecystectomy sun yi kama da waɗanda ke cikin masu ciwon sukari a cikin wannan.
A cikin matasa 26 na shekaru 12-17, harma da yara 4 zuwa shekaru 10-12, marasa lafiya masu fama da ciwon sukari na 2, kashi ɗaya na ƙananan (1 MG) na maganin sun nuna sakamako kama da manya.
Wanene aka wajabta maganin?
Allunan an ba su allunan don nau'in ciwon sukari na 2 idan glycemic iko ta hanyar canza yanayin bai isa ba. Zai yuwu a tsara magunguna a matsayin ƙarin ƙari, a cikin hadaddun farke tare da sauran wakilai na hypoglycemic.
Wanda ba a nuna glimepiride ba
Magungunan ba su dace da masu ciwon sukari masu kamuwa da cuta ta 1 ba; ba'a amfani dasu don kamuwa da cutar ketoacidosis, coma da precoma, har ma da babban koda da lalata hanta.
Kamar kowane magani, ba a sanya maganin glimepiride don masu ciwon sukari tare da babban ji game da sinadaran da ke cikin tsari, har ma da sauran magunguna na sulfonylamide.
Glimepiride yana contraindicated a cikin ciki da lactation.
Yadda ake amfani da Glimepiride daidai
Don tabbatar da sarrafa glycemic 100%, maganin ƙwaƙwalwar ƙwayar cuta bai isa ba.
Tsarin tabbatacce na ɗaukar nauyin tsoka a cikin ciwon sukari na nau'in haske na 2 da na tsakiya na iya zama kamar haka:
- Darasi mai ƙarfi - 2-3 p / mako;
- Tafiya mai kuzari - 3 rubles / mako .;
- Waha, keke, tennis ko rawa;
- Tafiya, tafiya mai natsuwa - kullun.
Idan irin wannan hadaddun bai dace ba, zaku iya yin aikin motsa jiki a kowace rana. A cikin wurin zama, mai ciwon sukari na iya zama ba tare da hutu ba na tsawon minti 30.
An zaɓi mafi kyawun maganin warkewa ta likita, yin la'akari da matakin cutar, rikice-rikice masu rikice-rikice, yanayin gaba ɗaya, shekarun mai haƙuri, yanayin jikinsa ga miyagun ƙwayoyi.
Umarnin Glimepiride don amfani yana bada shawarar yin amfani da 1 MG / rana. (a farawa). Tare da yawaita na makonni 1-2, lokacin da ya yiwu a kimanta sakamakon, ana iya sanya shi kyauta idan tsarin aikin magani na baya bai da tasiri sosai. Ka'idar ta fi 4 MG / rana. amfani a lokuta na musamman. Matsakaicin adadin magani shine har zuwa 6 MG / rana.
Idan matsakaicin ƙwayar metformin ba ta ba da iko na glycemic 100%, ana iya ɗaukar Glimepiride azaman maganin tallafawa a lokaci guda, ana haɗa shi daidai da wannan ƙwayar, har ma da magungunan haɗin gwiwa tare da waɗannan abubuwan haɗin gwiwar guda biyu da aka saki. Cikakken magani yana farawa da mafi ƙarancin ƙwayar glimepiride (1 g), saka idanu na yau da kullum na alamomin glucometer zai taimaka wajen daidaita daidaitaccen. Duk canje-canje zuwa algorithm ana yin su ne kawai a ƙarƙashin kulawa na likita.
Wataƙila haɗuwa da glimepiride kuma tare da shirye-shiryen insulin. Sashi na allunan, a wannan yanayin, dole ne ya zama ɗan ƙaramin abu. Dangane da sakamakon gwaje-gwajen, kowane mako biyu ana amfani da maganin.
Yawancin lokaci, kashi ɗaya na magani. Hada shi da m karin kumallo ko abinci bayan shi, idan karin kumallo a cikin masu ciwon sukari alamu ne.
Zai fi kyau a ɗauki kwaya 'yan mintoci kaɗan kafin cin abinci, saboda yana ɗaukar lokaci don aiwatarwa. Idan baku bata lokacin daukar Glimepiride ba, yakamata a sha magani a farkon damar, ba tare da canza sashi ba.
Idan ƙaramin kashi na Glimepiride yana haifar da bayyanar cututtuka na hypoglycemia, an soke maganin, tunda ya isa ga mai haƙuri ya sarrafa sukarinsa da ingantaccen abinci, yanayi mai kyau, bin yarda da bacci da hutawa, isasshen aikin jiki.
Lokacin da aka sami cikakken iko na ciwon sukari, juriya na hormone na iya raguwa, wanda ke nufin cewa a tsawon lokaci, buƙatar magani zai ragu. Hakanan wajibi ne don sake duba sashi tare da asarar nauyi kwatsam, canje-canje a cikin yanayin aikin jiki, ƙara yanayin damuwa da sauran abubuwan da ke haifar da rikicewar glycemic.
Yiwuwar sauyawa daga wasu wakilai na maganin cututtukan jini zuwa glimepiride
Lokacin juyawa daga zaɓin magani na madadin don ciwon sukari na type 2 tare da wakilai na baka, ana yin la'akari da rabin rayuwar magungunan da suka gabata. Idan maganin yana da tsayi tsawon lokaci (kamar chlorpropamide), dole a kiyaye hutu na kwanaki da yawa kafin canzawa zuwa glimepiride. Wannan zai rage damar haɓakar haɓakawar jiki sakamakon ƙari na tasirin jami'ai 2. Lokacin maye gurbin kwayoyi, ana bada shawarar farawa a mafi ƙarancin 1 mg / rana. Ana aiwatar da taken a ƙarƙashin yanayi iri ɗaya.
Sauyawa insulin na Glimepiride a cikin masu ciwon sukari tare da nau'in cuta na 2 ana yin shi a cikin matsanancin yanayi kuma a karkashin kulawa na likita koyaushe.
Side effects
Don maganin glimepiride, da sauran magungunan sulfa, an tabbatar da ingantaccen tabbacin ingancin ingancin su. Nazarin asibiti ya kuma bincika amincin su. Dangane da shawarwarin WHO, ana tantance hadarin bunkasa tasirin abin da ba'a so ba akan ma'auni:
- Mafi yawan lokuta ≥ 0.1;
- Sau da yawa: daga 0.1 zuwa 0.01;
- Rashin daidaituwa: daga 0.01 zuwa 0.001;
- Da wuya: daga 0.001 zuwa 0.0001;
- Da wuya <0, 00001;
- Ba a sani ba idan, bisa ga ƙididdigar da ke akwai, ba shi yiwuwa a tantance girman haɗarin.
Sakamakon halayen jiki daga bangarori daban-daban da tsarin an gabatar dasu a cikin tebur. Yawancin su ba su dawwama kuma suna wucewa da kansu bayan maye gurbin maganin.
| Talakawa da tsarin | M halayen | Yawan bayyanar |
| Tsarin kewaya | granulocytopenia, thrombocytopenia, leukopenia, erythropenia, agranulocytosis, anemia, pancytopenia | da wuya |
| Rashin rigakafi | leukocytoclastic vasculitis, hauhawar jin ci gaba, gajeruwar numfashi, saukar da karfin jini har ya girgiza | da wuya |
| Rashin lafiyar metabolism | haɓaka cikin hanzari kuma yana da wahala a daidaita yanayin rashin lafiyar | da wuya |
| Hankali | canje-canje a cikin glycemia na iya haifar da kumburin wucin gadi na ɗan lokaci | ba a sani ba |
| Gastrointestinal fili | rikicewar dyspeptik, raunin epigastric, cin zarafi na rashin nasara (ba da shawarar dakatar da maganin ba) | da wuya |
| Tsarin maganin hepatobiliary | karuwa a cikin hanta enzymes, dysfunctions kamar jaundice ko choleostasis | ba a sani ba da wuya |
| Fata | itching, kurji, urticaria, daukar hoto | ba a sani ba |
| Bayanan dakin gwaje-gwaje | sauke cikin sodium taro - hyponatremia | da wuya |
Taimaka tare da yawan wuce haddi
Babban haɗarin haɗarin zubar da jini na Glimepiride shine hypoglycemia wanda ya kasance har zuwa awanni 72, bayan daidaituwa, komawa na iya yiwuwa. Alamar farko na yawan abin sama da ya kamata na iya faruwa ne kwana guda bayan sha maganin. Tare da irin wannan bayyanar cututtuka (cuta dyspeptik, ciwon kirji), ana buƙatar kulawa da wanda aka azabtar a cikin cibiyar likita. Tare da hypoglycemia, cututtukan cututtukan jijiyoyi suma suna yuwuwar: wahayi na gani da daidaituwa, rawar hannu, damuwa, matsanancin ciki, tashin zuciya, ƙwayar cuta.
Taimako na farko idan an sami yawan zubar da ruwa shine rigakafin sha na wuce haddi ta hanyar wanke ciki. Kuna buƙatar haifar da gag reflex ta kowace hanya, sannan ku sha gawayi da ke aiki ko wani adsorbent da wasu laxative (alal misali, sodium sulfate). A lokaci guda, dole ne a kira motar asibiti don asibiti mai gaggawa.
Za a shigar da wanda aka azabtar da shi tare da glucose a cikin ciki: na farko, 50 ml na maganin 50%, to - 10%. Duk lokacin da zai yiwu, kuna buƙatar bincika matakin sukari a cikin plasma. Baya ga takamaiman magani, ana amfani da Symptomatic.
Idan yaro da gangan ya ɗauki glimepiride, an zaɓi sashin glucose ta la'akari da yuwuwar haɓakar haɓakar jini. Ana kimanta matakin haɗarin lokaci-lokaci tare da glucometer.
Glimepiride yayin daukar ciki
Fitowar jiki daga tsari a cikin jini yayin daukar ciki na iya haifar da mummunar cutar tayin ciki har ma da mutuwar haihuwa, kuma sigogi na glycemic a wannan batun ba su bane. Don rage haɗarin teratogenic, mace tana buƙatar kulawa da bayanin bayanan glycemic ɗinta a kai a kai.
Idan mai ciki - mai ciwon sukari da nau'in cuta ta 2, an canza shi zuwa ɗan lokaci zuwa insulin. Matan da suka riga sun kasance a matakin shiryawa na yaro ya kamata su gargaɗi mahaɗan endocrinologist game da canje-canje masu zuwa don gyara tsarin kulawa.
Babu wani bayani game da illolin cutar tayin ɗan adam na glimepiride. Idan muka mai da hankali kan sakamakon binciken dabbobi masu juna biyu, ƙwayar tana da guba ta haihuwar da ta shafi tasirin hypoglycemic na glimepiride.
Ba a tabbatar da ko maganin ya shiga cikin madarar mahaifiyar ba, amma magani ya shiga cikin madarar mahaifiyar a cikin beraye, saboda haka ana kuma fasa allunan a lokacin shayarwa. Tunda sauran magunguna na jerin maganin sulfonylomide sun shiga cikin madarar nono, haɗarin hauhawar jini a cikin jariri yana da gaske.
Yara
Babu bayanai game da amfani da miyagun ƙwayoyi ga yara masu fama da cutar sukari a ƙarƙashin shekaru 8. Don tsufa (har zuwa shekaru 17), akwai wasu shawarwari don amfani da maganin azaman maganin monotherapy. Bayanin da aka buga bai isa don amfani da miyagun ƙwayoyi ta wannan rukuni na masu ciwon sukari ba, saboda haka
Siffofin Glimepiride Jiyya
Sun sha kwayoyin a mintuna kaɗan kafin cin abinci don maganin ya sha kuma ya fara aiki. Tare da isasshen diyya don ƙarfin maganin tare da carbohydrates, zai iya tsokani yanayi na rashin ƙarfi. Za a iya gane hari ta hanyar cikakkiyar alamomin masu zuwa: ciwon kai, ci, wolfish, dyspeptic cuta, isomnia, sabon abu farfadowa, bayyanar tashin hankali, hana hanawa, karuwar damuwa, damuwa, hangen nesa da magana, rikicewar hankali, asarar hankali da iko, raunin kwakwalwa, fainting , precom da kuma coma. Ana nuna Adrenergic counterregulation ta hanyar kara yawan zufa, dabino, rudani, tashin zuciya, tashin zuciya, ciwon zuciya.
Experiencewarewa a cikin lura da masu ciwon sukari tare da analogues na jerin hanyoyin sulfonylomide ya nuna cewa, duk da tabbataccen tasiri na matakan dakatar da kai harin, akwai haɗarin sake faruwarsa. Hanya mai ƙarfi da tsawan jini, wanda lokaci-lokaci na al'ada a ƙarƙashin rinjayar sukari na yau da kullun, ya ƙunshi magani na gaggawa, gami da yanayi mai tsayi. Abubuwan da ke biyo baya suna kara haɗarin hypoglycemic:
- Yin watsi da shawarar likita, rashin iya aiki tare;
- Abubuwan da ake buƙata na jin dadi, abinci mara kyau, abinci mara ƙima saboda yanayin zamantakewar al'umma mara kyau;
- Rashin bin ka'idodin abinci mai ƙarancin-carb;
- Rashin daidaituwa tsakanin adadin jijiyoyin wuya da yawan adadin carbohydrates;
- Haramcin giya, musamman tare da rashin abinci mai gina jiki;
- Renal da hepatic dysfunctions;
- Yawan yawan ƙwayar glimepiride;
- Decompensated endocrine pathologies da suka shafi tafiyar matakai na rayuwa (pituitary ko adrenal insufficiency, thyroid dysfunction);
- Amfani da wasu magunguna na lokaci daya
Tare da maganin ƙwayar cuta, ana buƙatar saka idanu akai-akai game da glycemia. Don kaucewa rikice-rikice, ya zama dole a sha wasu gwaje-gwaje a kai a kai:
- Ana bincika aikin wasan haemoglobin - 1 lokaci / watanni 3-4;
- Tattaunawa da likitan mahaifa, likitan dabbobi, likitan zuciya, likitan zuciyar - idan ya cancanta;
- Microalbuminuria - sau 2 / shekara;
- Kimantawa na bayanan lipid + BH - 1 lokaci / shekara;
- Nazarin kafafu - 1 lokaci / watanni 3;
- HELL - lokaci 1 / wata;
- ECG - 1 lokaci / shekara;
- Nazarin gaba ɗaya - 1 lokaci / shekara.
Yana da muhimmanci a lura da aikin hanta da kuma abubuwanda suka shafi jini, musamman rabewar platelet da farin sel.
Idan jiki yana fuskantar matsananciyar damuwa (raunin jiki, ƙonewa, tiyata, mummunan cututtuka), maye gurbin allunan na ɗan lokaci tare da insulin zai yiwu.
Babu wani gogewa game da amfani da magani don lura da masu ciwon sukari tare da matsanancin hepatic, kazalika da marasa lafiyar hemodialysis. A cikin dysfunctions na koda ko hepatic, ana canza shi da mai ciwon sukari zuwa insulin.
Glimepiride ya ƙunshi lactose. Idan mai ciwon sukari yana da rashin jituwa ga kwayoyin halittar ga galactose, rashi lactase, malabsorption na galactose-glucose, ana bashi magani na maye gurbin.
Sakamakon glimepiride akan ikon sarrafa abubuwa masu rikitarwa
Ba a gudanar da bincike na musamman game da glimepiride akan ikon tuka motoci ko aiki a samarwa a yankin mai haɗari ba a gudanar da shi. Amma, tunda miyagun ƙwayoyi suna da tasirin sakamako a cikin hanyar hypoglycemia, akwai haɗarin raguwa a cikin saurin halayen da tattara hankalin saboda hangen nesa mai rauni da sauran alamun cutar.
Lokacin da yake rubuta magani, ya kamata a faɗakar da mai ciwon suga game da haɗarin mummunan sakamako lokacin da ake sarrafa magunannun hanyoyin. Gaskiya ne gaskiya ga waɗanda yawanci suna da yanayin rashin ƙarfi, da kuma waɗanda basu iya gane alamun cutar matsala mai zuwa ba.
Sakamakon hulɗa tare da wasu magunguna
Amfani da magunguna na yau da kullun na iya haifar da mai ciwon sukari don haɓaka ƙarfin ƙwayar cuta ta glimepiride kuma ta hana kayan ta. Wasu magunguna ba su da tsaka tsaki lokacin amfani da su tare. Anwararren masani ne kaɗai zai iya ba da cikakken ƙididdigar jituwa game da yarda, saboda haka, lokacin ƙirƙirar tsarin magani, ya zama dole a faɗakar da endocrinologist game da duk magungunan da mai ciwon sukari ya riga ya ɗauka don magance cututtukan haɗuwa.
Effectarfafa tasirin hypoglycemic na Glimepiride yana tsokane amfani da phenylbutazone, azapropazone da oxyphenbutazone, insulin da maganganun maganganu, magungunan sulfanilamides, metformin, tetracyclines, MAO inhibitors, salicylic aminocyclinolonololan , miconazole, fenfluramine, rashin biyayya, pentoxifylline, fibrates, tritocvalian, ACE inhibitors, fluconazole , Fluoxetine, allopurinol, simpatolitikov, cyclo, Trojan da phosphamide.
Abun hanawar karfin jini na glimepiride yana yiwuwa tare da maganin haɗin gwiwa tare da estrogens, saluretics, diuretics, glucocorticoids, abubuwan haɓaka thyroid, abubuwan ƙira na phenothiazine, adrenaline, chlorpromazine, mai juyayi; nicotinic acid (musamman a babban sashi), laxatives (tare da tsawan lokaci), phenytoin, diazoxide, glucagon, barbiturates, rifampicin, acetosolamide.
Ana ba da tasirin da ba a iya faɗi ba ta hanyar hadadden magani tare da β-blockers, clonidine da reserpine, gami da shan barasa.
Glimepiride yana da ikon rage ko ƙara tasiri a jikin abubuwan da aka samo na coumarin.
Nazarin Glimepiride
Glimepiride, a cewar likitoci da marasa lafiya, magani ne mai matuƙar tasiri. An bayar da amincinsa cikin ƙananan allurai, yana kuma da ƙarin featuresarin fasalulluka waɗanda ba za su iya yin farin ciki ba sai dai su yi farin ciki. Amma, kamar dukkan magungunan maganin cututtukan cututtukan ƙwayar cuta, anail anaal na Amiil yana da amfani kawai idan mai ciwon sukari kansa ya taimaka masa.
- Olga Grigoryevna, Yankin Moscow. Ina shan kwamfutar hannu na Glimepiride (2 MG) kafin karin kumallo, da kuma bayan cin abinci - Hakanan tsawan Metforminum da safe da maraice na 1000 MG. Idan ban yi zunubi tare da abincin ba, to, za su ci gaba da maganin. Ban san wanda ya fi girma girma ba, amma a lokutan hutu, lokacin da yake da wuya a guji liyafa da cin abinci, Ina shan 3 MG na Glimepiride. An ayyana mini magani a polyclinic gwargwadon rage yawan sayan magani, shi ya sa komai ya dace da ni.
- Andrey Vitalievich, Yekaterinburg. Kimanin shekaru 3 an umurce ni da Amaril, na sha sau 4 da safe. Sannan a asibitin babu Amaril kyauta, sun maye gurbinsa da Glimepirid, jigon kuɗi. Na yi ƙoƙari in ɗauka daidai gwargwado - sukari ya yi tsalle zuwa 12 mmol / l (ya kasance bai fi 8 ba). Likita ya karu da kaso zuwa 6 mg, komai ya yi kyau, amma har yanzu na sayi Amaril. Kuma sake, 4 MG kowace rana ya ishe ni. Amma tabbas zan dawo cikin tsarin analog na kyauta, saboda har yanzu ina siyan magungunan zuciya da kwayayen kwaladi. Abun tausayi ne ya soke Amaril kyauta.
- Masu warkarwa na gargajiya sunyi imani cewa nau'in ciwon sukari na 2 ba kawai cuta ba ce daga cutar rashin abinci mai gina jiki da rayuwa mai rauni, amma kuma daga rashin iya jin daɗin rayuwa, daga damuwa. Don amsa su daidai, dole ne ku kasance mai jituwa, ana nufin soyayya.
