Glucophage Long 500, 750, 1000 - umarnin da sake dubawa na mai haƙuri

Metformin yana ɗayan magungunan da ake yawan amfani da su don ciwon sukari. Yana da sauƙin rage haemoglobin glycated da haɗarin rikice-rikice da ƙananan ƙwayoyin cuta, duk da haka, kwata na marasa lafiya tare da shi suna ɗaukar narkewar narkewa, har zuwa 10% na masu ciwon sukari sun ƙi magani don wannan dalili. Sabuwar ƙwayar cuta tare da metformin Glucofage Long ta Merck Sante ta ƙirƙiri musamman don magance waɗannan matsalolin. Ya inganta haƙuri da Allunan, ƙara da haƙuri da ciwon sukari marasa lafiya zuwa wajabta jiyya.

An sami wannan sakamakon ta amfani da sashi na musamman na Glucofage Long, wanda ke ba ka damar rage yawan metformin zuwa jini, cimma daidaitaccen taro, don haka rage haɗarin sakamako masu illa. A wannan yanayin, sakamakon maganin ba ya lalacewa kwata-kwata. Yawancin karatu da yawa sun nuna cewa aikin rage yawan glucose na Glucophage da Glucophage Long iri daya ne.

Yaya Glucophage Long

Yanzu duk al'ummomin endocrinologist suna ba da shawarar Metformin don fara magani don masu ciwon sukari na 2. Ba ya haifar da hypoglycemia, wanda ke da haɗari musamman ga marasa lafiya tsofaffi, ba ya haifar da karuwar nauyi, amma a'a yana taimakawa rage nauyi.

Glucophage Long allunan suna rage postprandial biyu da na tashin hankali, ba tare da motsa insulin ba. Umarnin don amfani yana nuna abubuwa uku waɗanda ke tantance tasirin saurin sukari:

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

1. Rage yawan fitowar glucose daga hanta ana samunsa ta hanyar hana samuwar glucose daga kwayoyi marasa amfani da sinadarai da glycogen.
2. Inganta ƙwayar glucose tsoka da kuma amfani ta rage rage insulin juriya.
3. Saurin sauke shaƙar glucose a cikin narkewa, yana juyar da jujjuyawar shi zuwa lactate. Lokacin shan maganin, ƙauracewar abinci daga ciki, wanda yawanci yana haɓaka cikin masu ciwon sukari, yana rage gudu. Yawancin bita sun nuna cewa wannan matakin yana ba marasa lafiya damar sauya halayen cin abinci, da kuma sauƙaƙe asarar nauyi.

Tare da yin amfani da yau da kullun, ƙwayar ta rage muhimmanci mita da tsananin rikitarwa na ciwon sukari. Rashin haɗarin rikicewar jijiyoyin bugun zuciya, bugun zuciya, gabaɗaya yawan mace-macen masu kiba ya rage da kashi uku bisa uku, mace-mace daga sakamakon cutar sankara - ta 42%. Ba za a iya bayanin irin waɗannan kyakkyawan sakamako ba kawai ta hanyar biyan diyya don ciwon sukari. Sakamakon bincike, an gano cewa metformin ya furta kaddarorin angioprotective waɗanda ba su da alaƙa da tasirin maganin a cikin glycemia. Daga cikin magungunan da ake amfani da su don kamuwa da cutar siga, waɗannan kaddarorin na musamman ne.

Effectsarin tasirin Kwayoyin Glucophage Long, suna da amfani ga masu cutar siga:

Yin hukunci da sake dubawa, na musamman sha'awa ga masu ciwon sukari masu nauyi da marasa lafiya da ke fama da cutar metabolism shine tasirin metformin don asarar nauyi. Suna iya sha'awar sakamakon ɗayan karatun ta amfani da metformin, orlistat (Xenical) da sibutramine (Reduxin). Marasa lafiya ba su canza matakin motsa jiki ba, amma an shawarce su da su rage yawan abincin da suke samu a maraice. An fara amfani da Metformin tare da allunan Glucofage Long 500 bisa ga umarnin, sannu a hankali ya karu zuwa 1500 MG a cikin marasa lafiya tare da BMI <30, har zuwa 2000 MG don BMI <35, kuma zuwa matsakaicin kaso na BMI ≥35.

Alamu don magani

A cikin "Nuna" ɓangaren umarnin don amfani da Glucophage Long - nau'in ciwon sukari guda 2 kawai. Ya kamata a tsara maganin tare da rage cin abinci da ilimin motsa jiki, haɗinsa tare da sauran allunan rage sukari da insulin ya samu karbuwa.

A zahirin gaskiya, kewayon aikace-aikacen Glucofage Long yana da fadi sosai. Ana iya sanya shi:

1. Don lura da ciwon sukari. Metformin yana rage yiwuwar cutar mellitus na ciwon sukari tare da rikice-rikicen ƙananan ƙwayar cuta da aka gano.
2. A matsayin ɗayan kayan aikin jiyya na cututtukan metabolism, tare da kwayoyi don gyaran halayen lipid na jini, magungunan antihypertensive.
3. Marasa lafiya tare da kiba mai yawa, wanda a mafi yawan lokuta yana haɗuwa da juriya na insulin. Glucofage Tsawanin Allunan suna taimakawa rage matakan insulin, wanda ke nufin hanzarta aiwatar da rushewar kitse da "fara" nauyi asara.
4. Mata da PCOS. An gano cewa metformin yana da tasiri mai motsa rai a kan ovulation. Dangane da sake dubawa, wannan magani yana ƙara yiwuwar samun juna biyu tare da polycystic.
5. Nau'in masu ciwon sukari na 1 da ke ɗauke da nauyin jiki mai yawa da yawan ƙwayar insulin na yau da kullun don haɓaka asarar nauyi da rage buƙatar hormone na wucin gadi.

Akwai shaidun cewa Glucofage Long yana da ikon rage haɗarin wasu nau'in cutar kansa, amma a cikin aikin asibiti ba a yi amfani da wannan matakin ba.

Pharmacokinetics

Babban bambanci tsakanin Glucofage Long da magabata shine keɓaɓɓen magunguna na sabuwar ƙwayar cuta. Tushen kwamfutar hannu na tsawan metformin tsarin tsarin polymer ne mai kashi biyu. Tsarin ciki yana ƙunshe da metformin, na waje yana da kariya. Bayan shan kwaya, babban murfin ya wuce ruwa, kumburin ciki yana juyawa zuwa gel. Sakamakon wannan, lokacin da kwayayen da ke cikin ciki ke ƙaruwa. Magani a hankali ana fito da shi daga ciki na ciki, sai ya shiga cikin matsanancin waje kuma ya shiga cikin jini. A wannan yanayin, 90% na kayan aiki suna fitowa a cikin sa'o'i 10. Don kwatantawa, metformin daga Glucofage na yau da kullun yana aiki iri ɗaya a cikin minti 30.

Bayanai daga umarnin don kantin magunguna na Glucofage Long:

Wani sabon nau'in magungunan yana ba ka damar:

1. Tabletsauki allunan sau ɗaya a rana, saboda tasirinsu yana rufe sa'o'i 24 ko fiye. Dangane da sake dubawar masu ciwon sukari waɗanda suka shiga cikin binciken, irin wannan tsarin yana rage yiwuwar rasa wani kwaya.
2. Da muhimmanci rage haɗarin tasirin tasirin halayen metformin na yau da kullun. Wannan fa'idodin sakamako ne sakamakon sakin abubuwa a hankali cikin jini, wanda ke rage girman hankalinsa da kashi 25%.
3. Sauƙaƙe zaɓi na kashi don marasa lafiya. Yawan sakin metformin daga kwamfutar hannu baya dogaro da halayen narkewa irin na masu ciwon sukari, abubuwan da ke cikin abinci.

Nazarin ya nuna cewa babu wani banbanci game da tasiri na Glucofage Long da Glucofage, yayin da Glucophage ya rasa cikin sharuddan haƙuri na metformin da kuma yarda da haƙuri na masu haƙuri ga magani.

Farashin magani tare da Glucophagem Long shine 2-2.5 sau fiye da Glucofagem:

M madadin m Glucofage Long

Metformin mai dogon aiki yana samun karbuwa sosai. Baya ga kamfanin Merck, sauran masana'antun sun fara samar da shi. Wadannan magungunan ana daukar su analogues na Glucophage Long; lokacin yin rajista, dole ne su tabbatar da daidaiton su na asali. Koyaya, a cikin rahotannin likitoci da kuma sake dubawa game da masu ciwon sukari, akwai da'awar lokaci-lokaci cewa analogues yana haifar da sakamako masu illa fiye da na asali na Glucofage Long, amma har yanzu ƙasa da metformin na yau da kullun. Farashin analog ɗin yayi ƙasa kaɗan, tunda mai sana'anta baya buƙatar gudanar da karatun aminci da gano tasirin magani.

Daga cikin magungunan da aka yi wa rajista a cikin Tarayyar Rasha, an kara da metformin na Rasha ya hada da Metformin Long Canon (wanda Canonpharma ya samar), Metformin MV (Izvarino), Formmetin Long (Pharmstandart, Biosynthesis), Gliformin Prolong (Akrikhin), Israel Metformin MV-Teva, Indian Diaformin OD.

Farashin allunan 60 na 750 MG na Metformin Canon da Formetin Long shine 310 rubles, wanda shine sau 1.5 mafi arha fiye da Glucofage Long na sashi ɗaya.

Yadda za a sha da sashi

Glucofage Dogon Allunan suna bugu da abinci, an sha su da ruwa. Koyarwar ta ba da shawarar ko dai ɗaukar duka maganin da aka tsara a lokacin abincin dare, ko rarraba shi cikin abincin dare da karin kumallo Don kiyaye tsawon lokacin fitowar metformin, kwamfutar hannu yakamata a bugu duka ba tare da murƙushewa ba. Glucophage Long 1000 za'a iya karye cikin rabi.

A cikin ciwon sukari na mellitus, an zaɓi sashi gwargwadon doka kamar metformin na yau da kullun: muna farawa da farawa kuma muna haɓaka shi a hankali har sai glycemia ta zama al'ada.

Glucophage Long 500 MG

Farawa kashi - 500 MG. Idan babu sakamako masu illa, ana iya haɓaka shi bayan makonni 2 daga farkon jiyya. Ya kamata a ƙara yawan sashi zuwa 500 MG a kowane mako 2 har sai sukari ya isa daidai. Abin da ya fi muni da yarda da miyagun ƙwayoyi, jinkirin da karuwa ya kamata. Matsakaicin izini na metformin lokacin shan Glucofage Long 500 shine Allunan 4. Idan bai rama ba game da cutar sankara, ana ƙara wani magani mai rage sukari a cikin tsarin kulawa.

Glucofage Long 500 don shan asara mai nauyi a cikin adadin 1500 MG, tare da nauyi mai yawa da kuma rashin contraindications, ana iya karɓar sashi a hankali har zuwa matsakaicin.

Glucophage Long 750 MG

Glucophage Long 750 an yi niyya ne ga marasa lafiya da ke fama da cutar sankara tare da fara babban cutar glycemia. Tare da taimakonsa, zaku iya hanzarta kai matakin warkewa. Yawan farawa na magani shine kwamfutar hannu 1, suna shan shi a abincin dare. Ana karuwa da kashi sau biyu a wata ta 750 MG. Dangane da endocrinologists, kashi mafi inganci ga yawancin marasa lafiya shine allunan 2. Umarni don amfani yana tabbatar da iyakar adadin izini mai mahimmanci - 2250 MG. An yarda da metformin na yau da kullun 3000 MG, don haka marasa lafiya da ke fama da babban insulin juriya ba za su iya canzawa daga Glucophage zuwa Glucofage Long ba.

M sakamako masu illa

Yawancin marasa lafiya waɗanda zasu iya yin nasarar raunin cutar sankara tare da metformin an tilasta su ƙi shan shi a cikin makonni na farko na magani. Don wannan ana tilasta su ta hanyar narkewar cuta, waɗanda sune sakamako masu illa na miyagun ƙwayoyi. Za a iya rage haɗarin su ta hanyar ƙara yawan hankali, shan metformin a lokaci guda tare da abinci kuma kawai da yamma. Dangane da sake dubawa, alamu marasa dadi a hankali suna raunana kuma a ƙarshen farkon watan farko na magani galibi sukan ɓace.

Idan sakamakon cututtukan gastrointestinal ya tsoma baki ga rayuwa ta al'ada ko kuma tsayawa na dogon lokaci, endocrinologists suna ba da shawarar ɗaukar glucophage na tsawanta ko analog ɗin ta. A cikin rabin maganganun, canjin magani yana haɗuwa tare da ɓacewa ko mahimmancin sakamako masu illa.

Lissafi da mita (a cikin%) na yiwuwar cututtukan gastrointestinal:

Sauran umarnin suna kira ragowar sakamako marasa illa na Glucofage wani abu ne mai saurin gaske, a cewar mai ƙira, ƙasa da 0.01% na marasa lafiya suna haɗuwa da su:

• halayen rashin lafiyan ana bayyana su sau da yawa a cikin yanayin itching da urticaria;
• rushewar hanta, haɓakar hanta enzymes. Wannan sakamako na gefen yawanci baya buƙatar magani kuma ya ɓace akan kansa bayan karɓar Glucophage Long;
• rashi na bitamin B12 tare da raunin jiyya;
• lactic acidosis yakan faru sau da yawa tare da gazawar koda, wanda ke haifar da urination mai narkewa na metformin. Hadarin lactic acidosis yana ƙaruwa ta hanyar hypoxia, barasa, tsawan azumi.

Ga wanda da miyagun ƙwayoyi ne contraindicated

Lactic acidosis yanayi ne mai matukar hatsari. Yawan adadin masu mutuwa a cikin masu fama da cutar sankara tare da lactic acidosis ya fi girma idan aka kwatanta da sauran rikice-rikice masu ciwon sukari. Metformin yana ƙaruwa da yawan lactate a cikin jiki, sabili da haka, a cikin contraindications don amfanin sa, umarnin ya haɗa da duk yanayi wanda haɗarin lactic acidosis ke ƙaruwa. Waɗannan su ne duk wasu cututtukan da ke haifar da hypoxia: zuciya, koda da gazawar numfashi, ƙonewa, rashin ruwa sakamakon amai ko gudawa, cututtukan da ke damun su, musamman cututtukan numfashi da cututtukan hanji. Ba za ku iya ɗaukar Glucophage Tsayi tare da isasshen adadin kuzari (ƙasa da 1000 a kowace rana), shan giya, maye mai yawa. Da fatan za a lura cewa aikin metformin ya wuce kwana guda, saboda haka ba za ku iya shan kwaya da safe ba kuma ku sha giya da yamma.

Contraindications sun haɗa da kowane yanayin m a cikin masu ciwon sukari, a lokacin wanda ba shi yiwuwa a sarrafa glycemia tare da Allunan, kuma maganin insulin ya zama dole. Waɗannan duk rikice-rikice ne na ciwon sukari, ba tare da la'akari da matakin su ba, rauni mai yawa, ƙonewa, shirye-shiryen gaggawa da aikin tiyata na gaggawa da ke buƙatar maganin tashin hankali gaba ɗaya.

Amfani da juna biyu

Metformin zai iya shiga daga jinin mahaifiyar cikin jinin tayi. Koyaya, baya haifar da rikicewar cutar haihuwar ciki, baya ƙaruwa da macewar ƙwayar cuta cikin ciki. Akwai shawarwari da magungunan na iya haifar da sakamako masu illa a cikin yaro, amma ba a same su ba a cikin karatun da ake da su. A cikin Rasha, daukar ciki shine cikakken contraindication na metformin. Yin hukunci da sake dubawa, koda kuwa ba a yi amfani da maganin ba bisa ga alamu (haɓaka aikin ƙwayar ƙwayar ƙwayar ciki), an soke ta tare da farawar ciki. A cikin Turai, an yarda da metformin don maganin ciwon sukari.

Kayan zai iya shiga cikin madarar nono, kuma daga shi zuwa cikin narkewa da jini na jariri. Tare da lactation, koyarwar ta ba ku damar ɗaukar Glucofage Long da analogues na miyagun ƙwayoyi tare da taka tsantsan kuma kawai idan fa'idinta ya fi ƙarfin cutar da yarinyar. Wannan na iya zama juriya na insulin a hade tare da kiba, kuma, gwargwadon haka, buƙatuwar adadin insulin. Don asarar nauyi bayan haihuwa ko don rage glycemia dan kadan, ba a yawan amfani da metformin yayin lactation.

Haɗuwa da sauran magunguna

Wasu abubuwa na iya shafar magunguna na Glucophage Long, suna kara haɗarin tasirin sakamako:

Abin da suke faɗi game da Glucophage Long