Magungunan Liraglutid an yi amfani da shi sosai a cikin 2009, ana amfani da shi sosai don kula da kiba a cikin nau'in 2 na ciwon sukari. Wannan wakili na hypoglycemic an allurar, an yarda da shi don amfani a ƙasashe da yawa na duniya, ciki har da Rasha. Da farko, an yi allurar a karkashin sunan kasuwanci Viktoza, tun a shekarar 2015, ana iya siyan magani a karkashin sunan Saksenda.
A sauƙaƙe, abu ɗaya mai aiki a ƙarƙashin sunaye na cinikayya daban-daban yana aiki daidai yadda yakamata, yana taimaka wa kula da ciwon sukari na 2 da babban dalilinsa - kiba mai wahala dabam dabam.
Liraglutide kwatancen roba ne na kwayar glucagon-kamar mutum, tana kama da tsarinta kamar misalin kashi 97%. Yayin amfani da miyagun ƙwayoyi, jikin ba ya bambanta tsakanin ainihin peptides waɗanda aka kafa a cikin jikin mutum da kuma na wucin gadi. Maganin yana ɗaure wa masu karɓa na dole, yana kunna samar da glucagon, insulin. Bayan wani lokaci, hanyoyin da ke tattare da keɓancewar insulin sune keɓancewa, ta yadda za a sami daidaituwar sukarin jini.
Penetrating zuwa cikin jini ta hanyar allura, Lyraglutide (Viktoza) yana kara matakin peptides, yana dawo da hanji, yana magance glycemia. Godiya ga warkewa, cikakkiyar ma'anar dukkanin abubuwan amfani daga abinci an lura, mai haƙuri yana kawar da:
- alamu bayyanar cututtuka na ciwon sukari;
- matsanancin nauyi.
Matsakaicin farashin maganin yana daga 9 zuwa 14 dubu rubles.
Umarnin don amfani da miyagun ƙwayoyi
Liraglutide don lura da nau'in ciwon sukari na 2 na ciwon sukari da kuma kiba dole ne a yi amfani dasu a cikin sashi na Saksenda, ana iya siyan ta ta azaman sirinji. An shirya rarrabuwa a kan sirinji, suna taimakawa wajen tantance ainihin yawan magungunan kuma yana sauƙaƙe gudanarwarsa. Thearfafa yawan abu mai aiki shine daga 0.6 zuwa 3 MG, mataki shine 0.6 MG.
Rana don manya tare da kiba da ciwon sukari na buƙatar 3 MG na miyagun ƙwayoyi, yayin da lokacin rana, ɗaukar abinci da sauran magunguna ba sa taka rawa ta musamman. A cikin makon farko na jiyya, kowace rana wajibi ne don allurar 0.6 mg, kowane mako mai zuwa amfani da sashi ya karu da 0.6 MG. Tuni a cikin mako na biyar na jiyya kuma kafin ƙarshen hanya, ana ba da shawarar yin allurar fiye da 3 MG kowace rana.
Ya kamata a gudanar da magunguna sau ɗaya a rana, saboda wannan kafada, ciki ko cinya ya dace sosai. Mai haƙuri na iya canza lokacin gudanar da maganin, amma wannan bai kamata a nuna a cikin kashi ba. Don asarar nauyi, ana amfani da miyagun ƙwayoyi don dalilai na endocrinologist.
Yawanci, miyagun ƙwayoyi Viktoza ya zama dole ga masu ciwon sukari irin na 2 waɗanda ba za su iya yin nauyi ba kuma suna daidaita yanayin su akan asalin:
- maganin rage cin abinci;
- shan kwayoyi don rage sukari.
Hakanan yana da mahimmanci a yi amfani da magani don maido da ƙwayar cuta a cikin marasa lafiyar da ke fama da canje-canje a matakan glucose.
Babban contraindications
Ba za a iya ba da magani ba a gaban rashin haƙuri na mutum zuwa ga abubuwan da aka haɗa, ƙararraki na nau'in ciwon sukari na 1, mummunan lalacewar hanta, kodan, bugun zuciya 3 da digiri 4.
Contraindications don amfani zasu zama cututtukan hanji mai kumburi, ƙarancin damuwa da cututtukan ƙwayar cuta a cikin glandar thyroid, ciki da shayarwa, cututtukan endocrine neoplasia da yawa.
Likitocin ba su ba da shawarar Liraglutide concomitantly tare da allurar da za a iya amfani da ita ga marasa lafiya da ke da shekaru 75 da haihuwa, tare da tabbatar da kumburi da ke cikin farji (pancreatitis), yayin jiyya tare da masu maganin antagonist na GLP-1.
Tare da matsanancin taka tsantsan, an wajabta maganin maganin kiba mai nau'in masu ciwon suga da ke dauke da cututtukan zuciya da jijiyoyin jini. Yau ba a kafa yadda allurar za ta yi amfani da shi ba yayin amfani da shi tare da wasu magunguna don daidaita nauyin jikin mutum.
A wannan yanayin, marasa lafiya da masu ciwon sukari kada su gudanar da gwaje-gwaje kuma su yi amfani da duk hanyoyin likita don kawar da kiba. Yiwuwar yin amfani da Liraglutide don masu ciwon sukari masu nauyi a ƙarƙashin shekara 18, dole ne a ƙayyade dacewa da irin wannan magani bayan:
- cikakken bincike na jikin mutum;
- wucewa gwaje-gwaje.
Sai kawai idan an cika wannan yanayin, mai haƙuri ba zai cutar da kansa ba.
Side effects
Liraglutide don kula da kiba a wasu halayen yana haifar da rushewar narkewar abinci, a kusan 40% na lokuta shine tashin zuciya da amai. Kowane mai cutar sankara da ke shan magani yana fama da gudawa ko kuma maƙarƙashiya.
Kimanin 8% na marasa lafiya da ke shan miyagun ƙwayoyi game da kiba sun koka da yawan kiba da gajiya. Kowane mara lafiya na uku tare da tsawaita amfani da injections yana da hypoglycemia, a wannan yanayin, sukari jini ya sauka zuwa matsanancin matakan.
Babu wataƙila mummunan rashin lafiyar halayen jiki bayan ɗaukar kowane nau'in Victoza sune: ciwon kai, rashin lafiyar jiki, cututtukan zuciya na hanji, hauhawar zuciya, ƙwanƙwasa, zazzabin ciwon sukari.
Duk wani tasirin da ba'a so ba yawanci yana ci gaba ne a ranar farko ko ta biyu na maganin, to yawanci da tsananin alamun alamu a hankali suke ɓace. Tunda liraglutide yana haifar da matsaloli tare da motsawar hanji, wannan yana tasiri tasiri na wasu kwayoyi da aka yi amfani da su.
Koyaya, irin waɗannan ƙetare ba su da girma sosai, ana iya gyara yanayin ta hanyar daidaita matakan magunguna. An yarda da amfani da maganin tare da magunguna, waɗanda suka haɗa abubuwa:
- metformin;
- karafarinas
Tare da irin waɗannan haɗuwa, magani yana gudana ba tare da halayen da ba a cutar da su ba.
Tasiri don Rage nauyi
Magungunan da aka danganta da sinadaran abinci mai narkewar jiki na taimaka wa masu ciwon sukari su rasa nauyi da farko ta hanyar hana darajar rage abinci, kuma a sakamakon haka, mutum ya ci kasa, baya samun kiba a jiki.
Nessarfin maganin yana da yawan lokuta mafi girma idan ana amfani dashi azaman ƙari ga abincin mai-kalori mara yawa. Ba za a iya yin allurar rigakafi azaman babbar hanyar kawar da kiba ba, maganin a wannan yanayin ba zai yi aiki sosai ba.
An nuna shi gaba ɗaya barin jaraba, ƙara ƙaruwa da tsawon lokacin aiki. Wannan yana taimakawa rage nauyi zuwa rabin nau'in masu ciwon sukari masu shan Victoza.
Gabaɗaya, kusan kashi 80% na marasa lafiya na iya dogara akan ingantaccen kuzarin ciwon sukari.
Dangane da sake dubawa, ana iya samun sakamako irin wannan idan kusan duk hanyar magani ta allurar da maganin ta hanyar ƙarancin 3 MG.
Farashin, analogues na miyagun ƙwayoyi
Kudin injections an ƙaddara shi da adadin babban abu mai aiki. Victose don subcutaneous management na 6 MG / ml - daga 10 dubu rubles; katako tare da alkalami na syringe 6 mg / ml - daga 9.5 dubu, Viktoza 18 MG / 3 ml - daga 9 dubu rubles; Saksenda don subcutaneous management na 6 MG / ml - 27 dubu.
Magungunan Liraglutide yana da alamun analogues da yawa a lokaci daya waɗanda ke da irin wannan tasirin akan jikin mutum: Novonorm (wanda aka yi amfani dashi don kula da ciwon sukari, glycemia yana raguwa), Baeta (yana nufin amidopeptides, yana hana narkewar ciki, rage cin abinci).
Ga wasu marasa lafiya, analog ɗin maganin Lixumia ya dace, yana daidaita ƙwayar cutar glycemia ba tare da la'akari da yawan abinci ba. Hakanan zaka iya amfani da magani na Forsig, ya zama dole don hana shan sukari, rage aikinta bayan cin abinci.
Yaya ingancin maganin kiba a cikin sukari tare da Lyraglutide, kawai likitan halartar ya kamata ya ƙayyade. Tare da shan magungunan kai, halayen da ba'a so na jiki kusan haɓaka koyaushe; ba zai yiwu a sami sakamako na warkewa ba.
Hatsari da magani ga kiba a cikin cututtukan fata za a rufe su a bidiyo a wannan labarin.
