Duk da cewa masana kimiyya sun sami nasarar maimaita kwayar insulin, wanda aka samar a jikin mutum, aikin kwayar halittar har yanzu ya zama an sassauta saboda lokacin da ake buƙatar shan jini. Magunguna na farko na inganta aikin shine Humalog insulin. Zai fara aiki riga na mintina 15 bayan allura, don haka sukari daga jini ya koma cikin kyallen takarda ta hanyar da ta dace, kuma har ma da gajeran lokaci ba ya faruwa.
Idan aka kwatanta da insulins na mutum da aka haɓaka a baya, Humalog yana nuna kyakkyawan sakamako: a cikin marasa lafiya, ana rage canzawar yau da kullum a cikin sukari da kashi 22%, glycemic indices sun haɓaka, musamman da rana, kuma da alama tsananin rashin jinkiri na raguwar hauhawar jini ya ragu. Sakamakon azumin, amma tsayayyen aiki, ana ƙara amfani da wannan insulin a cikin ciwon sukari.
Bruef umarnin
Umarni game da amfani da insulin Humalog abu ne mai cike da ƙima, kuma sassan da suke bayyana illolin sakamako da kwatance don amfani da sakin layi sama da ɗaya. Bayani mai tsawo da ke rakiyar wasu magunguna ana samun su ta hanyar marasa lafiya a matsayin gargadi game da haɗarin shan su. A zahiri, komai kishi ne daidai: babban umarni, - shaidar da yawa gwajicewa magani samu nasarar tsayayya.
Ciwon sukari da hauhawar jini zai zama abin da ya wuce
- Normalization na sukari -95%
- Cirewa kan jijiyoyin mara wuya - 70%
- Cire zuciyar mai karfin zuciya -90%
- Rabu da cutar hawan jini - 92%
- Increasearuwar kuzarin rana, inganta bacci da dare -97%
An amince da Humalogue don amfani da shi sama da shekaru 20 da suka gabata, yanzu ba shi da haɗari a ce wannan insulin ɗin yana da lafiya a gwargwadon gwargwado. An yarda da shi don amfani da tsofaffi da yara; ana iya amfani dashi a duk halaye tare da rashi mai ƙarfi na hormone: nau'in 1 da nau'in ciwon sukari na 2, ciwon suga na gestational, da tiyata.
Janar bayani game da Humalogue:
| Bayanin | Cire bayani. Yana buƙatar yanayi na ajiya na musamman, idan an keta su, zai iya rasa kaddarorinsa ba tare da canza bayyanar ba, saboda haka, za'a iya siye magungunan a cikin kantin magunguna. |
| Ka'idojin aiki | Yana ba da glucose a cikin kyallen, yana inganta juyar da glucose a cikin hanta, kuma yana hana fashewar kitse. Tasirin rage sukari yana farawa daga insulin gajere, kuma yana kasawa. |
| Form | Magani tare da taro na U100, gudanarwa - maɓallin juji ko ciki. Sanya cikin katako ko kuma alƙawarin sirinji da za'a iya zubar dashi. |
| Mai masana'anta | Maganin shine kawai Lilly Faransa, Faransa ta samar. An shirya shirya a Faransa, Amurka da Russia. |
| Farashi | A Rasha, farashin kunshin da ke ɗauke da katako 5 na 3 ml kowane kusan 1800 rubles. A cikin Turai, farashin irin wannan abu ya yi daidai da ɗaya. A cikin Amurka, wannan insulin kusan sau 10 ya fi tsada. |
| Alamu |
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| Contraindications | Mutane daya-daya dauki ga insulin lyspro ko kayan taimako. Mafi yawan lokuta ana bayyanawa cikin rashin lafiyan a wurin allurar. Tare da ƙarancin ƙarfi, yana wuce mako guda bayan ya canza zuwa wannan insulin. Mummunan lokuta ba kasafai ba ne, suna buƙatar maye gurbin Humalog tare da analogues. |
| Siffofin sauyawa zuwa Humalog | Yayin zaɓin kashi, ana buƙatar ƙarin ma'auni na glycemia, ana buƙatar shawarwari na yau da kullun na likita. A matsayinka na mai mulkin, mai ciwon sukari yana buƙatar ƙarancin Humalog a 1 XE fiye da gajeren insulin ɗan adam. Increasedarin buƙatar haɓakar hormone ana lura dashi yayin cututtuka daban-daban, damuwa mai juyayi, da aiki na jiki. |
| Yawan damuwa | Wucewa kashi yana haifar da hauhawar jini. Don kawar da shi, kuna buƙatar ɗaukar carbohydrates mai sauri. Mummunan shari'ar na bukatar kulawa ta gaggawa cikin gaggawa. |
| Hadin gwiwa tare da wasu magunguna | Humalog na iya rage aiki:
Inganta sakamako:
Idan wasu magungunan ba za su iya maye gurbin wasu ba, kashi na Humalog ya kamata a daidaita shi na ɗan lokaci. |
| Adanawa | A cikin firiji - shekaru 3, a zazzabi a daki - makonni 4. |
Daga cikin sakamako masu illa, cututtukan cututtukan zuciya da cututtukan ƙwayar cuta ana lura da su sau da yawa (1-10% na masu ciwon sukari). Kasa da 1% na marasa lafiya suna haɓakar lipodystrophy a wurin allurar. Mitar wasu halayen masu rauni ba su wuce 0.1% ba.
Abu mafi mahimmanci game da Humalog
A gida, ana gudanar da Humalog a cikin yanki ta amfani da alkairin sirinji ko famfon insulin. Idan za a kawar da cututtukan hawan jini, ana cikin gudanar da aikin cikin jijiyoyin likita. A wannan yanayin, yawan sarrafa sukari akai-akai wajibi ne don kauce wa yawan abin sha.
Insulin Humalog
Abubuwan da ke aiki na miyagun ƙwayoyi shine insulin lispro. Ya bambanta da kwayoyin halittar mutum a cikin tsarin amino acid a cikin kwayoyin. Irin wannan canjin baya hana masu karɓar tantanin halitta tantance kwayoyin halittar, don haka suna iya sanya sukari cikin kansu cikin sauƙi. Humalogue ta ƙunshi kawai monomers na insulin - guda, kwayoyin da ba a haɗa su ba. Saboda wannan, ana shan shi da sauri kuma a ko'ina, yana fara aiki don rage sukari da sauri fiye da insulin al'ada na al'ada.
Humalog magani ne da ya fi guntu aiki, misali, Humulin ko Actrapid. Dangane da rarrabuwa, ana nufin analogs insulin tare da aikin ultrashort. Farkon aikinsa yana da sauri, game da mintina 15, don haka masu ciwon sukari ba su jira har sai miyagun ƙwayoyi ya yi aiki, amma kuna iya shirya abinci nan da nan bayan allura. Godiya ga wannan ɗan gajeren rashi, ya zama mafi sauƙi ga shirya abinci, kuma haɗarin manta abinci bayan allura ya ragu sosai.
Don ingantaccen iko na glycemic, ya kamata a haɗa insulin da sauri tare da yin amfani da insulin na tsawon lokaci. Iyakar abin da ya keɓance shine amfani da famfo na insulin akan aikin mai gudana.
Yankan zaɓi
Maganin Humalog ya dogara da dalilai da yawa kuma an ƙayyade daban-daban ga kowane masu ciwon sukari. Yin amfani da tsarin yau da kullun ba a bada shawarar ba, saboda suna ƙaruwa da raunin ciwon sukari. Idan mai haƙuri ya bi tsarin abincin carb, ƙarancin Humalog na iya ƙasa da daidaitattun hanyoyin gudanarwar gwamnati na iya samarwa. A wannan yanayin, ana bada shawara don amfani da insulin mai rauni mai rauni.
Ultrashort hormone yana ba da tasiri sosai. Lokacin canzawa zuwa Humalog, ana ƙididdige farkon kashi 40% na ɗan gajeren insulin da aka yi amfani dashi a baya. Dangane da sakamakon glycemia, an daidaita sashi. Matsakaicin buƙata don shirye-shiryen kowane yanki burodi shine raka'a 1-1.5.
Jadawalin allura
Tsarin humalogue yana da abinci kafin kowane abinci, akalla sau uku a rana. Game da sukari mai yawa, ana ba da izinin poplings tsakanin manyan injections. Umarnin don amfani yana da shawarar yin lissafin adadin insulin da ake buƙata dangane da carbohydrates da aka shirya don abinci na gaba. Kimanin mintina 15 ya kamata ya wuce daga allura zuwa abinci.
Dangane da sake dubawa, wannan lokacin ba shi da yawa, musamman da rana, lokacin jure insulin yana ƙasa. Yawan shaye shaye ne na mutum, ana iya yin amfani da shi ta amfani da maimaita matakan glucose din jini nan da nan bayan allura. Idan an lura da sakamako na hypoglycemic da sauri fiye da umarnin, an saita rage lokacin da abinci zai rage.
Humalog shine ɗayan magunguna mafi sauri, saboda haka yana da dacewa don amfani dashi azaman taimakon gaggawa don ciwon sukari idan ana barazanar mai haƙuri tare da ƙwayar cutar hauka.
Lokacin aiki (gajere ko tsawo)
An lura da girman insulin ultrashort a cikin mintuna 60 bayan gudanarwarsa. Tsawan lokacin da aka aiwatar ya dogara da kashi, idan ya fi girma, tsawon sa yana rage tasirin sukari, a matsakaici - kimanin awa 4.
Humalog mix 25
Don kimantawa daidai da tasirin Humalog, dole ne a auna glucose bayan wannan lokacin, yawanci ana yin wannan kafin abinci na gaba. Ana buƙatar ma'aunin farko idan ana zargin hypoglycemia.
Shortarancin gajeren lokacin Humalog ba matsala bane, amma fa'idodin maganin. Godiya gareshi, marasa lafiya da ke dauke da cutar sankarar mellitus ba su da yiwuwar fuskantar hauhawar jini, musamman da dare.
Humalog Mix
Baya ga Humalog, kamfanin magunguna Lilly Faransa yana samar da Humalog Mix. Cakuda ne na insulin lispro da furotin protamine. Godiya ga wannan haɗin, lokacin farawa na hormone yana kasancewa cikin sauri, kuma tsawon lokacin aiki yana ƙaruwa sosai.
Humalog Mix yana samuwa a cikin taro biyu:
| Magunguna | Abin da ke ciki,% | |
| Lyspro insulin | Dakatar da insulin da protamine | |
| Humalog Mix 50 | 50 | 50 |
| Humalog Mix 25 | 25 | 75 |
Amfanin kawai irin waɗannan kwayoyi shine hanya mafi sauƙi na allurar rigakafi. Sakamakon ciwon sukari mellitus yayin yin amfani da su ya fi muni tare da tsarin kulawa da insulin na motsa jiki da kuma amfani da Humalog na yau da kullun, sabili da haka, don Yara Humalog Mix ba a amfani da su.
An wajabta wannan insulin:
- Masu ciwon sukari waɗanda ba sa iya yin lissafin ɗayan kai-tsaye ko kuma yin allura, alal misali, saboda hangen nesa mara kyau, gurguwa ko rawar jiki.
- Marasa lafiya tare da rashin hankali.
- Tsofaffi marasa lafiya da ke da yawa rikice-rikice na ciwon sukari da ƙarancin hangen nesa na magani idan ba sa son su koyi ka'idodin lissafin insulin.
- Masu ciwon sukari masu fama da cuta ta 2, idan har ana samar da nasu hormone.
Kula da ciwon sukari tare da Humalog Mix yana buƙatar tsayayyen tsarin abinci, kayan snack a tsakanin abinci. An ba shi damar cin abinci har zuwa 3 XE don karin kumallo, har zuwa 4 XE don abincin rana da abincin dare, kusan 2 XE don abincin dare, da 4 XE kafin lokacin bacci.
Analogs na Humalog
Lyspro insulin a matsayin abu mai aiki yana ƙunshe ne kawai a cikin Humalog na asali. Magungunan da ke kusa da su sun kasance NovoRapid (dangane da aspart) da Apidra (glulisin). Wadannan kayan aikin suma yanada matattakala, dan haka bashi da mahimmanci wanda zaba. Dukkansu suna da haƙuri da kyau kuma suna samar da raguwa cikin sauri a cikin sukari. A matsayinka na doka, ana ba da fifiko ga maganin, wanda za'a iya samun kyauta a asibiti.
Canjin daga Humalog zuwa analog ɗinsa na iya zama dole yayin yanayin rashin lafiyar. Idan mai ciwon sukari ya manne da tsarin karancin abinci mai karafa, ko kuma yawanci yana dauke da cutar rashin jini, zai fi dacewa mutum yayi amfani da mutum maimakon insulin ultrashort.
