Fructosamine don ciwon sukari

Wasu daga cikin sunadarai a cikin jininmu suna cikin sukari, nau'i mai fasali. Mafi girman matakan glucose na yau da kullun, mafi girma yawan adadin sunadarai waɗanda ke amsawa tare da shi. Don tantance matsayin diyya ga masu ciwon sukari, don sanin haɗarin wannan cuta, zaku iya amfani da bincike don fructosamine.

Duk da cewa ba kasafai aka tsara wannan binciken ba, yana da fa'ida sosai, musamman a lokacin zaɓin sabon magani. Ana iya amfani da matakin fructosamine don ƙididdige matsakaicin sukari a cikin makonnin da suka gabata da ƙaddara kimanin adadin haemoglobin glycated a ciki. A wasu halayen, wannan bincike ita ce hanya daya tilo da za'a gano a baya wacce ba a gano ba ta tashi a cikin sukari.

Fructosamine - menene?

Magunguna ya ƙunshi furotin a cikin tsari mai sauƙi - albumin. A jimlar adadin sunadarai, rabon ta shine kashi 52-68%. Yana da ƙananan ƙwayoyin halitta kuma yana da kyakkyawan ikon ɗaurewa. Godiya ga wannan, zai iya jigilar bilirubin, mai mai, wasu hormones da kwayoyi ta jiragen ruwa. Albumin ya sami damar amsawa tare da glucose. Fructosamine shine sakamakon irin wannan amsawar. Glycation yana gudana da sauri lokacin da sukari mai yawa a cikin jini kuma matakinsa ya hau tsawo na dogon lokaci. Tare da samuwar fructosamine, haemoglobin na sel jini kuma yana glycated.

Haɗin albumin tare da glucose ya tabbata. Bayan matakin sukari ya koma al'ada, fructosamine baya karyewa, amma yana ci gaba da kasancewa cikin jini. Protein yakan lalace ne kawai bayan makonni 2-3, duk wannan lokacin akwai alamun tsalle cikin sukari cikin jini. Kwayoyin jini suna rayuwa tsawon rai, har zuwa watanni 4, don haka adadin gemoclobin na glycated yana ba ku damar kimanta ingancin magani na tsawon lokaci fiye da matakin fructosamine.

Ciwon sukari da hauhawar jini zai zama abin da ya wuce

• Normalization na sukari -95%
• Cirewa kan jijiyoyin mara wuya - 70%
• Cire zuciyar mai karfin zuciya -90%
• Rabu da cutar hawan jini - 92%
• Increasearuwar kuzarin rana, inganta bacci da dare -97%

An fara bayanin binciken ne a 1982. Daga baya an gano cewa ana iya gano cutar sankara ta musamman ta matakin fructosamine, kuma tare da babban inganci - kusan 90%. Duk da wannan, binciken bai yadu ba, kuma ana amfani dashi azaman adjunct a hade tare da matakin glucose da haemoglobin.

Mara lafiyar mai ciwon sukari yana lura da rashin lafiyarsa kowace rana tare da glucometer. Idan ka tattara sakamakon binciken da alhakin, za a iya kiyasta matakin biyan diyya daidai gwargwado. A wannan yanayin, babu buƙatar bincike don fructosamine. Yawancin lokaci, likitoci suna amfani da shi yayin zaɓin tsarin kula da cututtukan cututtukan ƙwayar cuta: rubutaccen allurai na kwayoyi, matsakaicin adadin da aka yarda da carbohydrates, kuma bayan makonni 2, ana amfani da fructosamine don yin hukunci game da tasirin maganin.

Alamu

Binciken bincike na Fructosamine ya fi dacewa a cikin waɗannan lambobin:

1. Don tantance daidaito game da nadin magani makonni 2 bayan farawa.
2. Idan a rayuwar mai haƙuri da ciwon sukari akwai canje-canje masu mahimmanci ƙasa da makonni 6 da suka gabata. Irin waɗannan canje-canjen sun haɗa da sabon tsarin abinci, haɓaka matakin motsa jiki ko hutawa a cikin gado, tsawan cututtuka, musamman waɗanda endocrine.
3. A lokacin daukar ciki, tare da yin amfani da ma'aunin glucose na azumi. Glycated haemoglobin a wannan lokacin ba'a ƙaddara shi ba, tun da matsayin hormonal na mace, kuma tare da shi guluk ɗin jini, yawancin lokaci yakan canza. Yayin haihuwar jariri, ana amfani da bincike kan yawan ruwan fructosamine maimakon gemoclobin mai narkewa.
4. A cikin jarirai tare da matsalolin da ake zargi da metabolism metabolism. Sakamakon kasancewar haemoglobin fetal a cikin jinin jarirai, binciken da ake kan fructosamine shine kadai hanyar abin dogaro don tantance glycemia gaba daya.
5. A yanayin da gwajin na haemoglobin na iya zama ba za a iya dogara da shi ba sakamakon karancin haemoglobin: anemia; cututtukan jini; cututtukan jini na kullum sakamakon zubar jini, kumburin ciki, yawan haila; zub da jini a cikin watanni 3 da suka gabata; cutar hemolytic; jan jinin haila.
6. A cikin shirye-shiryen tiyata na tiyata, don tantance shiri na mai haƙuri da masu ciwon sukari mellitus gare su.
7. Idan akwai shakku kan bullar ciwukan haila na kwanan nan wanda ke shafar sukarin jini.

Yadda za'a ƙaddamar da bincike

Amfani da rashin tabbas na bincike akan fructosamine shine babban amincinsa. Babu wasu tsauraran bukatu don shiri, tunda sakamakon kusan ba ya shafar lokacin samin jini, abinci, motsa jiki da tashin hankali a ranar bayarwa.

Duk da wannan, dakunan gwaje-gwaje sun nemi manya su tsaya awanni 4-8 ba tare da abinci ba. Ga jarirai, lokacin azumi yakamata ya zama minti 40, ga yara ‘yan kasa da shekaru biyar - awa 2.5. Idan yana da wahala ga mai haƙuri da ciwon sukari ya iya tsayayya da irin wannan lokacin, zai isa ya guji cin abinci mai ƙiba. Man shafawa, kitse na dabbobi, romon mai kek, cuku na ɗan lokaci yana ƙara haɗakar lipids a cikin jini, wanda hakan na iya haifar da sakamako mai dorewa.

A gida, a halin yanzu ba zai yiwu a bincika ba, tunda an dakatar da sakin gwajin gwaji saboda babban kuskuren aunawa. A cikin marasa lafiyar da ke kwance a gado, ma'aikatan dakin gwaji za a iya ɗaukar kwayoyin halitta a gida, sannan a kawo su don bincike.

Yankewa

Sakamakon binciken ya bayyana a cikin micromoles ko millimoles kowace lita na jini.

Dokar da aka yarda da ita na fructosamine iri ɗaya ce a cikin maza, mata da matasa na duka maza da mata shekaru 14 da haihuwa. A cikin mafi yawan dakunan gwaje-gwaje, daidai yake da 205-285 mmol / L ko 2.05-2.85 mmol / L. Ga yara underan shekaru 14, kaɗan kaɗan: 195-271 μmol / L

Saboda gaskiyar cewa dakunan gwaje-gwaje na iya amfani da wata hanya daban don ƙayyade fructosamine da calibrators daga masana'antun daban-daban, ƙimomin zayyana don wannan bincike na iya bambanta dan kadan. Bayanin abin da kewayon yarda da matsayin yarda a cikin wannan dakin gwaje-gwaje kasance a kan kowane takardar sakamakon da aka bayar wa abokin ciniki.

Nazarin na asibiti na kula da ciwon sukari:

Nazarin sun gano cewa matsakaiciyar matakin fructosamine (F) na tsawon watanni 3 na iya lissafa adadin gemoclobin glycated (HG) a cikin haƙuri. Ana iya wakiltar dangantakar ta hanyar magana: GG = 0.017xF + 1.61, inda aka nuna GG a cikin%, Ф - in micromol / l. Bayan haka kuma: F = (GG-1.61) x58.82.

Hakanan akwai dogaro da matakin fructosamine akan matsakaicin sukari na jini a cikin makonni 2 da suka gabata:

Saboda haka, wannan bincike yana da ikon bayar da cikakken kimantawa game da yanayin rayuwa na mara lafiyar, ingancin magani.

Babban dalilin da fructosamine ya tashi shine mellitus na ciwon sukari da cuta ta baya. Dangane da shawarwarin asibiti, ba shi yiwuwa a yi wannan binciken bisa ga bincike guda. Wajibi ne don gudanar da ƙarin bincike da kuma ware sauran abubuwan da zasu iya ƙara yawan ƙwayar fructosamine:

• rashin kwayoyin cututtukan cututtukan zuciya;
• gazawar koda
• tsawanta karuwa a matakin immunoglobulin A saboda kamuwa da cuta, kumburi da ke jikin mutum; cututtukan autoimmune, cystic fibrosis, lalacewar hanta, giya;

Ana iya rage Fructosamine saboda dalilai masu zuwa:

• tsananin karancin sunadarai na jini, musamman albumin. Wataƙila wannan yana kasancewa da ƙarancin furotin a cikin abinci, wasu cututtukan hanta, narkewar abinci na narkewa a cikin narkewar abinci, da kuma cutar sankarar hanta a cikin matakan protein na volumetric proteinuria. Defarancin rashi furotin (idan matakin albumin shine> 30 g / l) baya tasiri sakamakon binciken;
• hawan jini;
• cin abinci na bitamin C da B na dogon lokaci

Binciken Farashi

A cikin ciwon sukari na mellitus, ana ba da jagorar yin bincike ta hanyar halartar likita - likita na iyali, mai ilimin hanyoyin kwantar da hankali ko endocrinologist. A wannan yanayin, binciken kyauta ne. A cikin dakunan gwaje-gwaje na kasuwanci, farashin bincike don maganin fructosamine ya ɗan ƙanƙanta fiye da farashin glucose mai azumi kuma kusan sau 2 yana da arha fiye da ƙudarin gemoclobin glycated. A cikin yankuna daban-daban, ya bambanta daga 250 zuwa 400 rubles.