Idan abincin rage rage kiba ba shi da inganci, za a iya ba da magunguna wadanda za su kawar da cin zarafin mai a jiki. Idan matakin jimlar cholesterol a cikin jini ya zama sama da 6.5 mmol / l, to likita na iya ba da shawarar kulawa ta musamman don rage shi a farkon wannan lokacin.
Babban rarrabuwa da kwayoyi
Da farko dai, ya kamata a lura da magunguna masu rage yawan rage kiba. Wadannan sun hada da:
- fibrates;
- gumaka
- anion musayar magunguna da kuma resins wanda ke rage shaƙar cholesterol a cikin hanji;
- nicotinic acid;
- probucol.
Dangane da tsarin aiwatarwa, ana iya raba wadannan kwayoyi zuwa bangarori da yawa:
- kwayoyi waɗanda ke hana haɓakar ƙarancin cholesterol (ana kuma kiranta mara kyau): statins, fibrates, nicotinic acid, probucol, benzaflavin;
- wakilai da za su iya rage gudu daga ƙwayar cholesterol: guar, masu bin acid acid;
- mai metabolism mai gyara wanda ke haɓaka ƙwayoyin cholesterol mai yawa: lipostabil, mahimmancin abubuwa.
Masu neman bile acid
Magunguna waɗanda ake bile acid ana yawan kiran su azaman musayar anion. Da zaran wadannan kwayoyi suka shiga hanjin, sai a kama acid din sannan a cire su daga jiki.
Latterarshe yana amsawa ga wannan tsari ta hanyar haifar da sabon haɗin acid bile daga shagunan cholesterol da ake dasu. Ana ɗaukar cholesterol daga cikin jini, wanda ke taimakawa rage shi.
Masana'antar harhada magunguna suna ba da magungunan cholestyramine mai narkewa, kazalika da colestipol, don rage cholesterol na jini. Ana iya amfani dasu a cikin allurai na 2-4, tare da sharadin tsararru na farko tare da ruwa.
Ragowar musayar anion ba su da ikon shiga cikin jini kuma suna "aiki" kawai a cikin lumen hanji. Saboda wannan takamaiman bayani, magungunan ba su da babban tasiri ga jikin mutum.
Sakamakon sakamako na iya haɗawa:
- bloating;
- tashin zuciya
- maƙarƙashiya.
Idan an cinye mayikan acid bile a cikin allurai masu yawa na dogon lokaci, to a wannan yanayin ana iya cin zarafin ɗaukar wasu bitamin, da kuma acid bile.
Magunguna a cikin wannan rukunin suna rage yawan abin da ake kira mummunan cholesterol, kasancewar triglycerides a cikin jini ya kasance a matakin ɗaya.
Abubuwan Kayan Cholesterol
Saboda jinkirin shan sinadarin cholesterol daga abinci, wannan rukunin magungunan na iya rage maida hankali. Mafi inganci shine guar. Wannan ƙarin abinci mai gina jiki yana da cikakken kariya kuma an samo shi daga zuriyar wake na hyacinth. Haɗin samfurin ya haɗa da polysaccharide, wanda, dangane da ruwa, ya juya zuwa jelly.
Guarem yana iya kawar da kwayar cholesterol a cikin ganuwar hanji. Bugu da kari, miyagun ƙwayoyi:
- yana hanzarta janyewar acid bile;
- rage rashin ci;
- taimaka rage yawan abincin da aka ci.
Wannan kayan maye shine yake a cikin nau'in manya da za'a kara shi a cikin abin sha. Amfani da maganin zai iya zama sauƙin hade tare da wasu hanyoyi.
Yayin amfani, ana iya haifar da sakamako masu illa, alal misali, yin murfin hular kwano, jin zafi a cikin hanji, tashin zuciya da ruwa. Wadannan alamun ba su da yawa kuma ba su faruwa ba. Ko da a rashin jiyya, suna wucewa da sauri, yayin da akwai raguwar tsari a cikin cholesterol na jini.
Acid Nicotinic Acid
Sinadarin Nikotinic da dukkan abubuwan da yake amfani dashi, misali:
- arifimox
- narinasar
- enduracin
Ainihin, su sune bitamin B Wadannan magungunan suna rage cholesterol-low mai yawa kuma suna kunna tsarin fibrinolysis, wanda ke taimakawa kara rage yiwuwar thrombosis. Yana nufin ya fi wasu magunguna rage rage kiba da ke kara haɓaka abubuwan cholesterol a cikin jinin mai haƙuri.
Jiyya tare da nicotinic acid yana ɗaukar lokaci mai tsawo tare da ƙaruwa mai mahimmanci akan sashi. Bayan ɗaukar shirye-shiryen, kafin wannan ya kamata ku sha ruwan sha, musamman kofi na halitta.
Niacin na iya kawo cikas ga bangon ciki, wanda baya amfani dashi idan ya shafi cututtukan fata da cututtukan zuciya. A cikin yawan adadin marasa lafiya, ana iya ganin gyadar fuska a farkon farfajiya, duk da haka, wannan alamar ta ɓace a kan lokaci. Don hana jan launi, kuna buƙatar sha 325 mg na asfirin rabin sa'a kafin amfani da miyagun ƙwayoyi.
Babban abubuwanda ke haifar da nicotinic acid sun hada da:
- hepatitis na kullum;
- gout
- zuciya tashin hankali.
Akwai magani wanda zai iya haifar da ƙarancin sakamako na sakamako masu illa kuma ya daɗe sosai - wannan enduracin ne.
Probucol
Probucol baya tasiri triglycerides, amma yana kuma daidaita ma'aunin mai kyau da mara kyau cholesterol a cikin jini. Allunan suna hana peroxidation na kitse kuma suna nuna tasirin anti-atherosclerotic, yana haifar da raguwa cikin cholesterol jini.
Sakamakon magani tare da Probucol za'a iya samun shi bayan watanni 2 kuma yana iya wuce zuwa watanni 6 bayan dakatarwar amfani dashi. Za'a iya haɗu da kayan aiki daidai tare da wasu kwayoyi waɗanda ke rage cholesterol.
Yayin aikin jiyya, za a iya fadada lokacin tazara tsakanin zuciya da ci gaban cututtukan zuciya. Don hana wannan yanayin, ya zama dole a sha wani ƙwaƙwalwar ƙwaƙwalwar ajiyar aƙalla 1 a cikin watanni 6.
Ba za a iya tsara Probucol lokaci guda tare da cordarone ba.
Abubuwan da suka shafi jiki sun hada da jin zafi a cikin ciki, tashin zuciya da gudawa.
Kada a sha miyagun ƙwayoyi tare da:
- arrhythmias na ventricular;
- aukuwa akai-akai na ischemia na myocardial;
- ƙananan matakan HDL.
Fibrates
Fibrates na iya jurewa yanayin matakan triglycerides, kazalika da tattarawar LDL da VLDL. Ana iya amfani dasu tare da mahimmancin hypertriglyceridemia. Mafi mashahuri za a iya kiransa waɗannan allunan:
- gemfibrozil (m, gevilon);
- fenofibrate (Tipantil 200 M, Tricor, Exlip);
- cyprofibrate (lipanor);
- choline fenofibrate (trilipix).
Ana iya danganta mummunan sakamako na amfani da jin zafi a cikin tsokoki, tashin zuciya da jin zafi a cikin ramin ciki. Fibrates na iya haɓaka abin da ya faru na kodan fitsari da mafitsara. Da wuya isa, ana hana faruwar jinin haiatopoiesis.
Ba za a iya tsara waɗannan magungunan don cututtuka na kodan, ƙwayar ciki da matsalolin jini ba.
Statins
Statins sune mafi ingancin ƙwayar ƙwayar cholesterol. Suna da ikon toshe wani enzyme na musamman wanda ke amsa samar da abu mai kama da mai a cikin hanta, yayinda yake rage maida hankali cikin jini. A lokaci guda, adadin masu karɓar LDL yana ƙaruwa, wanda ke ba da haɓaka don haɓakar haɓakar ƙwaƙwalwar ƙarancin ƙasa.
A matsayinka na mai mulkin, an tsara magungunan masu zuwa:
- simvastatin (vasilip, zokor, aries, simvageksal, simvakard, simvakor, simvastatin, simvastol, simvor, simlo, sincard, holvasim);
- lovastatin (cardiostatin, choletar);
- pravastatin;
- atorvastatin (anvistat, atocor, atomax, ator, atorvox, atoris, vazator, lipoford, lypimar, liptonorm, novostat, torvazin, torvakard, tulip);
- rosuvastatin (akorta, giciye, mertenyl, rosart, rosistark, rosucard, rosulip, roxer, rustor, tevastor);
- pitavastatin (livazo);
- fluvastatin (leskol).
Simvastatin, kazalika da lovastatin, an yi su ne daga fungi. Abubuwa iri ɗaya na allunan cholesterol masu girma suna zama metabolites mai aiki. Pravastatin wani sinadari ne na fungal wanda shine kanshi mai aiki.
Ana iya ba da shawarar Statins sau ɗaya kowace dare. An yi bayanin wannan tsarin ta hanyar gaskiya ne cewa ganakun kwayar cholesterol na faruwa a cikin dare. A tsawon lokaci, za a iya ƙara yawan kashi na mutum-mutumi, kuma za a sami ingantaccen aikinsa bayan kwanakin farko na gudanarwa, wanda zai iya kaiwa zuwa wata guda.
Insan Adam ba shi da isasshen lafiya ga ɗan adam, amma yana da matuƙar mahimmanci kada a yi amfani da manyan allurai, musamman tare da fibrates, wanda ke cike da matsalolin hanta.
Wasu marasa lafiya na iya samun rauni na tsoka da jin zafi a jiki. A wasu halaye, ana jin zafin ciki, maƙarƙashiya, tashin zuciya, da kuma rashin cikakken ci, rashin bacci da ciwon kai.
Wadannan kwayoyi don rage cholesterol ba su da ikon shafar carbohydrate da metaboline metabolism, wanda ke ba su damar amfani da su don matakan ƙona kiba, gout da ciwon suga. Lura cewa idan an lura da ƙwayar cholesterol a lokacin daukar ciki, ya zama dole a nemi likita tare da maganin.
Idan muka yi la’akari da tsare-tsaren kulawar gargajiya, to za a iya haɗa statins zuwa lura da atherosclerosis a matsayin monotherapy ko tare da wasu kwayoyi.
Pharmacology yana ba da hadadden shirye-shiryen haɗin gwiwa dangane da:
- lovastatin da acid nicotinic;
- ezetimibe da simvastatin;
- pravastatin da fenofibrate;
- rosuvastatin da ezetimibe.
Akwai bambance-bambancen abubuwa na statins da acetylsalicylic acid, atorvastatin da amlodipine.
Yin amfani da magunguna da aka yi da shiri ba wai kawai yana da fa'idodi ba kawai ta fuskar adana kuɗi, amma yana haifar da mafi ƙarancin sakamako masu illa.
