Don daidaita sukari na jini a cikin ciwon sukari, ana amfani da magunguna na rage sukari na musamman. Ana daukar Metformin magani sosai don gyara glycemia.
Magungunan yana da adadi mai yawa na ƙwayoyin cuta da kuma analogues na rukuni. Masu ciwon sukari suna da sha'awar, amma menene idan Metformin yana da sakamako masu illa? Tabbas, suna nan.
Amma nan da nan Ina so a lura cewa duk wani rikitarwa ya bayyana kawai tare da sashi mara daidai da aka zaɓa. Idan likita ya zaɓi adadin da ya dace, kuma kafin wannan a hankali karanta tarihin likitan haƙuri, to, yiwuwar tasirin sakamako ba kusan komai bane.
Farashi da hanyar aiwatar da maganin
Metformin magani ne na baki wanda ake amfani da shi daga rukunin biguanide. Menene farashin magani? A cikin kantin magani, matsakaicin farashin Metformin shine 120-200 rubles. Packaya daga cikin fakitin ya ƙunshi allunan 30.
Abubuwan da ke aiki da maganin shine metformin hydrochloride. Hakanan yana dauke da kayan taimako, kamar E171, propylene glycol, talc, hypromellose, silicon dioxide, magnesium stearate, sitaci masara, povidone.
Don haka menene tasirin magungunan metformin? Idan ka yi imani da umarnin don amfani da miyagun ƙwayoyi, to, sashin jikinta yana aiki kamar haka:
- Yana kawar da juriya na insulin. Wannan lamari ne mai mahimmanci, kamar yadda mutane da yawa masu ciwon sukari ke haɓaka juriya ga tasirin insulin. Wannan abu ne da ke tattare da haɓakar ƙwayar cutar mahaifa da sauran cututtukan cututtukan jini.
- Yana taimakawa rage jinkirin daukar glucose daga hanji. Saboda wannan, mara lafiya bashi da tsalle-tsalle a cikin sukari na jini. Amfani da madaidaicin sashi na Metformin, matakin glucose zai tabbata. Amma akwai gefen gefen tsabar kudin. Metformin hydrochloride a hade tare da ilimin insulin zai iya haifar da ci gaba na cutar hypoglycemic. Abin da ya sa tare da yin amfani da wannan magani a lokaci guda da kuma yin amfani da insulin, ana iya daidaita yin amfani da kashi.
- Yana hana gluconeogenesis a cikin hanta. Wannan tsari ya ƙunshi maye gurbin glucose, wanda jiki ke karɓa daga madadin hanyoyin samar da makamashi. Saboda jinkirin samar da glucose daga lactic acid, ana iya guje wa abubuwan sukari da sauran rikice-rikice na ciwon sukari.
- Yana rage yawan ci. Mafi sau da yawa, nau'in ciwon sukari na 2 shine sakamakon kiba. Abin da ya sa, a kan asalin tsarin maganin abinci, ana ba da haƙuri ga yin amfani da magunguna na taimako. Metformin na musamman ne a cikin irinta, saboda yana taimakawa ba kawai tsayar da sukari na jini ba, amma yana ƙara haɓaka tasirin maganin abinci ta hanyar 20-50%.
- Normalizes jini cholesterol. Lokacin amfani da Metformin, ana ganin raguwa a matakin triglycerides da ƙarancin lipoproteins mai yawa.
Metformin hydrochloride shima yana hana ayyukan peroxidation na mai. Wannan wani nau'in rigakafin cutar kansa ne.
Alamu da umarnin amfani da Metformin
A waɗanne yanayi ne amfanin Metformin ya dace? Idan kun yi imani da umarnin don amfani, za a iya amfani da magani a cikin lura da masu ciwon sukari na 2.
Haka kuma, za'a iya amfani da allunan azaman maganin tafintototo ko haɗin haɗi tare da sauran ma'aikatan hypoglycemic. Wani magani ana amfani dashi sosai a lokuta inda maganin rage cin abinci ba ya taimakawa ciwon sukari.
Yana da mahimmanci a san cewa alamomin yin amfani da Metformin basu iyakance ga wannan ba. Ana amfani da maganin sosai a cikin maganin cututtukan cututtukan cututtukan fata da na cleropolicystosis na ovaries. Daga cikin alamun da ake amfani da shi, cututtukan metabolism da kiba suma an bambanta su, tare da haɓakar juriya na insulin.
Yaya za a zabi sashi na Metformin? Za'a iya zaɓin maganin yau da kullun na Metformin gabaɗaya daban-daban. A wannan yanayin, dole ne likita ya san kansa da bayanan tarihin, tunda wannan wakilin hypoglycemic yana da contraindications da yawa don amfani.
Ina so a lura cewa akwai Metformin a cikin allurai. Zai iya zama 1000, 850, 500, 750 mg. Haka kuma, akwai magungunan ciwon sukari da aka haɗu waɗanda ke dauke da kusan 400 mg na metformin hydrochloride.
Don haka, abin da sashi har yanzu mafi kyau duka? Maganin farko na Metformin shine 500 MG, kuma yawan gudanarwa shine sau 2-3 a rana. Kuna buƙatar amfani da magani nan da nan bayan cin abinci.
Bayan 'yan makonni na jiyya, za a iya daidaita sashi matakin. Komai zai dogara da sukarin jini. Ana bada shawarar glycemia yau da kullun akan komai a ciki. Don waɗannan dalilai, ya fi kyau a yi amfani da glucometer.
Har yaushe Metformin yake ɗauka? Ba zai yiwu a amsa wannan tambayar ba. Lokacin zabar tsawon lokacin jiyya, za a la'akari da halayen mutum na musamman, musamman, matakin glucose na jini, nauyi da shekaru. Jiyya na iya ɗaukar kwanaki 15, kwana 21, ko “wuce” a wata.
Matsakaicin adadin Metformin shine 2000 MG kowace rana. Ya kamata a lura cewa tare da yin amfani da insulin lokaci guda, ya kamata a rage kashi zuwa 500-850 MG kowace rana.
Contraindications da fasali na miyagun ƙwayoyi
Kowane wakili mai rage sukari dole ne a zaɓi shi da kyau, saboda yana da contraindications don amfani. Yin watsi da koyan umarnin ba a yarda dashi ba, saboda wannan na iya zama mai muni.
Don haka, menene contraindications Metformin ke da shi? Strictaƙƙarfan contraindication don amfani shine rashin lafiyan ƙwayoyin metformin hydrochloride ko abubuwan da ke cikin maganin.
Hakanan sun hada da contraindications:
- M ko na kullum acidosis.
- Kwanan nan ya sha wahala infarction na zuciya.
- Ciki ko raunin zuciya.
- Kasancewar matsalolin koda. Ba a yarda da kayan aikin ga mutanen da ke fama da gazawar rashin aiki ba.
- Tsufa. Ba a sanya magani ba ga masu ciwon sukari wanda shekarunsu suka fi shekaru 80.
- Kasancewar lalacewar hanta ko wasu cututtukan cututtukan cututtukan cututtukan hepatobiliary.
- Exarancin motsa jiki ko tsayayyen abinci, wanda ke samar da raguwa mai yawa a cikin adadin caloric.
- Fitsari a sanadiyyar kasancewar cututtukan da suke kamawa.
- Al`amarin
Wani mummunar contraindication shine hypoxia, ciwon ciki da duodenal miki.
Sakamakon Gefen Maganin Metformin
Menene illolin sakamako na Metformin? Akwai irin wannan mahimmancin kamar haɗarin asali na wakilai na hypoglycemic, musamman Metformin. Me ya ƙunsa?
Gaskiyar ita ce tare da nau'in ciwon sukari na 2, mara lafiya dole ne a ko da yaushe kula da abubuwan da ke cikin kalori a cikin abincin, kuma musamman yawan carbohydrates a ciki. Idan mai ciwon sukari yayi amfani da wakilai na hypoglycemic, kuma ya zauna akan tsauraran abinci, to yuwuwar haɓakar haɓakar haɓaka yana da girma - raguwar haɓakar glucose na jini.
Daga cikin illolin sakamako na Metformin kuma ana iya rarrabe su:
- Take hakkin tsarin hematopoietic. Lokacin da aka yi amfani da Metformin, ba zai yiwu a fitar da yiwuwar maganin thrombocytopenia, leukocytopenia, erythrocytopenia, granulocytopenia, hemolytic anemia, pancytopenia. Amma ya kamata a lura cewa duk waɗannan rikice-rikicen sun jujjuya, kuma suna warware kansu bayan soke maganin.
- Rashin nasara a cikin hanta. Sun bayyana a matsayin ci gaban gazawar hanta da hepatitis. Amma bayan ƙin Metformin, waɗannan rikice-rikice sun warware kansu. An tabbatar da wannan ta hanyar nazarin likitoci da marasa lafiya.
- Ku ɗanɗani rikici. Wannan rikitarwa yakan faru sau da yawa. Ba a san ainihin madaidaicin aikin ci gaban tashin hankali game da tasirin metformin hydrochloride ba.
- Fashin fata, erythema, urticaria.
- Lactic acidosis. Wannan rikitarwa yana da haɗarin gaske. Kusanci yakan taso ne idan an zabi maganin da ba daidai ba, ko kuma mai ciwon sukari ya sha giya lokacin jiyya.
- Bala'i a cikin aikin narkewa. Irin wannan rikitarwa yana bayyana sau da yawa isa, kamar yadda aka gani ta hanyar bita da haƙuri. Rashin hankali a cikin narkewa na ciki yana bayyana ta hanyar tashin zuciya, amai, ɗanɗano mai ƙarfe a bakin, da kuma rashin ci. Amma cikin adalci ya kamata a lura cewa waɗannan rikice-rikice yawanci suna bayyana a farkon matakan jiyya, sannan su warware kansu.
- Rage sha na bitamin B12.
- Janar rauni.
- Hyma na jini.
Idan rikitattun abubuwan da ke sama suka bayyana, yana da kyau a yi amfani da ƙungiyar analogues na Metformin kuma a kula da cutar ta alama.
Tsarin Haɓaka Magunguna
Metformin yana rage glucose jini. Amma lokacin hulɗa tare da wasu magunguna, wannan magani yana haɓaka, ko akasin haka, yana rage tasirin hypoglycemic.
Wannan na iya haifar da sakamako mai maye. Ina so nan da nan in lura cewa tasirin hypoglycemic yana haɓaka haɓaka yayin haɗuwa da Metformin tare da abubuwan da aka samo na sulfonylurea. A wannan yanayin, ana buƙatar daidaita sashi.
Hakanan mai zuwa na iya ƙara ƙaruwa da tasirin tasirin jini na Metformin:
- Acarbose.
- Magungunan rigakafin ƙwayar cuta marasa lalacewa.
- Monoamine oxidase inhibitors.
- Maganin Kawaus.
- Angiotensin-mai canza mai hana enzyme.
- Harshen Cyclophosphamide.
- Abubuwan da aka samo daga clofibrate.
- Masu tallata Beta.
Corticosteroids, diuretics, analogues na samostanin rage tasirin maganin cutar sukari tare da Metformin. Hakanan an lura cewa tasirin hypoglycemic yana raguwa tare da amfani da glucagon, hormones thyroid, estrogens, nicotinic acid, antagonists na alli da isoniazids.
Hakanan dole ne a tuna cewa cimetomedin, lokacin hulɗa tare da Metformin, yana ƙaruwa da damar haɓakar lactic acidosis.
Wane irin magani za a iya amfani dashi tare da metformin?
A cikin lura da ciwon sukari, ƙwayar cuta irin su Janavia galibi ana wajabta ta tare da Metformin. Farashinsa shine 1300-1500 rubles. Babban sashin aiki mai maganin shine sitagliptin.
Wannan abu yana hana DPP-4 aiki, kuma yana ƙaruwa da haɗakar GLP-1 da HIP. Hormones na dangin mahaifa suna ɓoye a cikin hanji na kwana ɗaya, bayan haka matakan su ya tashi bayan cin abinci.
Abubuwan da ke faruwa a ciki wani bangare ne na tsarin ilimin halittar jiki don tsara glucose homeostasis. Tare da matakan sukari mai girma na jini, hormones daga wannan dangin yana ƙara yawan aikin insulin da ɓoyewar shi ta ƙwayoyin beta.
Yadda za a sha maganin? Maganin farawa shine 100 MG 1 lokaci ɗaya kowace rana. Amma kuma, likita mai halartar ya kamata zaɓi zaɓi mafi kyau duka. An ba da izinin gyara, musamman idan aka yi amfani da Januvia a cikin haɗin gwiwa tare da Metformin.
Contraindications wa yin amfani da Januvia:
- Type 1 ciwon sukari.
- Allergy ga maƙarƙashiya magunguna.
- Ketoacidosis mai ciwon sukari.
- Lokacin daukar ciki da lactation.
- Shekarun yara.
- Tare da taka tsantsan a gazawar hanta. Tare da dattiction na tsarin hepatobiliary, raguwar sashi na iya zama dole. Wannan an tabbatar da hakan ta hanyar bayanan bincike, da kuma sake duba masana game da ilimin kimiyyar halitta.
Shin maganin yana da sakamako masu illa? Tabbas, suna da wurin zama. Amma Januvia sau da yawa yakan haifar da rikicewa yayin da sashi ya hau zuwa 200 MG. Yayinda kake riƙe da ƙananan allurai, da yiwuwar tasirin sakamako ƙarancin abu ne.
Dangane da umarnin, lokacin shan kwayoyin, rikice-rikice kamar cututtuka na huhu, nasopharyngitis, ciwon kai, zawo, tashin zuciya, amai, arthralgia na iya haɓaka.
Hakanan, ba zai yiwu a fitar da yiwuwar rashin lafiyan halayen da cututtukan jini ba.
Mafi kyawun analog na Metformin
Mafi kyawun analog na Metformin shine Avandia. Wannan wakili na hypoglycemic yana da tsada sosai - 5000-5500 rubles. Packaya daga cikin fakitin ya ƙunshi allunan 28.
Abubuwan da ke aiki na miyagun ƙwayoyi shine rosiglitazone. Ana amfani da Avandia wajen lura da ciwon sukari na 2. Haka kuma, za'a iya amfani dashi a hade tare da Metformin, kuma za'a iya amfani dashi daban.
Yaya za a zabi lokacin shan kwayoyin? Dole ne a faɗi nan da nan cewa zaku iya shan maganin kafin ko bayan abinci. Maganin farko shine 4 MG kowace rana a allurai 1-2. Bayan makonni 6-8, ana iya ninka adadin daidai daidai sau biyu. Ana samun haɓaka idan a 4 mg na al'ada na sukari jini.
Contraindications zuwa yin amfani da miyagun ƙwayoyi:
- Type 1 ciwon sukari.
- Allergy ga abubuwan da ke cikin miyagun ƙwayoyi.
- Lokacin bacci.
- Shekarun yara (har zuwa shekaru 18).
- Ciki
- Zuciya mai rauni ko gazawar koda.
Lokacin amfani da Avandia, rikice-rikice daga gabobin tsarin numfashi ko tsarin jijiyoyin jini suna yiwuwa.
Haka kuma akwai yiwuwar kara girman jiki. Hakanan umarnin sun bada tabbacin cewa maganin na iya haifarda cutar rashin jini, rashin aiki na hanta da kuma hypercholesterolemia. Amma sake duba marasa haƙuri sun nuna cewa an yarda da warkewar warkewar cutar. Bidiyo a cikin wannan labarin zai yi magana game da yadda Metformin ke aiki.
