Hanyar warkewa don nau'in ciwon sukari na 2 na mellitus an kafa shi ba kawai ga abinci na musamman ba, har ma a kan m na samfuran roba da suka dace da cutar.
Suna da mahimmanci don cimma dabi'un glycemia na al'ada.
Daga cikin magunguna da yawa da kasuwar magunguna ke bayarwa, galibi ana ba masu haƙuri allunan Glibomet.
Babban bayani game da magani, tsari na saki da abun da ke ciki
Glibomet yana cikin rukunin magungunan cututtukan cututtukan da ake ɗauka na baka. Kamfanin ne na kasar Jamus BERLIN-CHEMIE / MENARINI ke yin maganin. Banda Glibomet a Rasha, ana yin rajista fiye da magunguna 100 na wannan kamfani, waɗanda ke amfani da su sosai wajen maganin cututtukan da yawa kuma sun riga sun sami nasarar dogara da marasa lafiya.
Ana sayar da miyagun ƙwayoyi a cikin nau'i na allunan mai rufi da farin harsashi. Kowane ɗayansu ya ƙunshi kayan aiki guda 2 da ɗimbin abubuwa masu taimako.
Kwamfutar hannu na miyagun ƙwayoyi ya ƙunshi:
- Glibenclamide (2.5 MG) da Metformin Hydrochloride (400 MG) sune manyan abubuwan;
- sitaci masara (mai gina jiki) - 57.5 MG;
- cellulose (polysaccharide shuka) - 65 MG;
- silicon dioxide (ƙarin abinci na abinci E551) - 20 MG;
- gelatin - 40 MG;
- Glycerol - 17.5 MG;
- talc (ma'adinai) - 15 MG;
- Diethyl phthalate (0.5 mg) da 2 mg Acetylphthalyl cellulose - suna a cikin kwalin allunan.
Kunshin na iya zama allunan 40, 60 ko 100.
Pharmacology da pharmacokinetics
Godiya ga abubuwan haɗin da ke cikin shirye-shiryen, ƙwayar ta rage nuna alamar glucose a cikin jinin mai haƙuri.
Tsarin magunguna na abu Glibenclamide:
- yana ƙarfafa ƙwayar insulin, kuma yana ƙara ƙaddamar da ƙwayar hormone;
- yana ba da gudummawa ga karuwar kamuwa da insulin a cikin jikin mutum;
- yana haɓaka tasirin insulin a kan glucose;
- yana rage jinkirin aiwatar da aikin lipolysis.
Tsarin magunguna na Metformin:
- yana taimakawa haɓaka haɓakar insulin, kuma yana haɓaka sakamako;
- lowers sha na glucose a cikin hanji, inganta sha ta wasu gabobin;
- yana ba da gudummawa ga murkushe gluconeogenesis;
- yana da kyau yana shafar narkewar abinci mai guba, wanda ke haifar da asarar nauyi.
Zai yuwu a cimma rage kiba a cikin ƙwayar cuta bayan kwaya bayan sa'o'i 2 da adana awowi 12.
Tasirin magungunan ƙwayar cuta ta hanyar halayen shaye-shaye, rarrabawa, metabolism da haɓaka manyan abubuwan.
Glibenclamide:
- Tsotsa da tsarin rarraba. Matsakaicin maida hankali akan abubuwan ya kai 2 sa'o'i bayan gudanarwa. An tattara kayan cikin hanzari daga narkewa kamar jijiyoyi (gastrointestinal fili). Haɗin abu tare da furotin plasma ya kai 97%.
- Tsarin metabolism yana faruwa kusan gaba ɗaya a cikin hanta.
- Kiwo. Regulation na wannan aikin ana yin shi ta hanta. Ana fitar da exclave din din ne tare tare da fitsari da bile ta hanyar fitsari. Cire rabin rayuwar yana ɗaukar awoyi 10.
Metformin:
- Shakarwa da rarrabewar a cikin kyallenyen bangaren yana faruwa da sauri da sauƙi.
- Fitar abubuwan da ke cikin jiki daga faruwa yakan zama ba su canzawa ta hanjin koda da hanjinsa. Cire rabin rayuwar yana ɗaukar awoyi 7.
Manuniya da contraindications don amfani
An ba da shawarar yin amfani da miyagun ƙwayoyi don amfani da ciwon sukari na 2, lokacin cin abinci da magani tare da wasu kwayoyi ba su da tasiri.
Yardajewa:
- rashin hankali ga kowane ɓangare na magungunan;
- nau'in ciwon sukari na 1;
- nau'in kwayar cutar sikari;
- lactic acidosis;
- ketoacidosis;
- coma (hypoglycemic ko hyperglycemic);
- matsanancin rauni na koda;
- Pathology na hanta, kodan;
- 'yan ta'adda
- kasancewar cututtuka masu yaduwa;
- ayyukan tiyata, tare da babban asarar jini;
- raunin da ya faru ko ƙonewa;
- kowane yanayin buƙatar yin amfani da ilimin insulin;
- leukopenia;
- porphyria;
- canje-canje dystrophic;
- barasa maye;
- lokacin shayarwa;
- yara, matasa marasa shekaru 18;
- ciki
Umarnin don amfani da umarni na musamman
Ana ɗaukar allunan a baki tare da abinci. Dole ne likita ya zaɓa sashi na miyagun ƙwayoyi, la'akari da tsarin aikin metabolism da glycemia a cikin haƙuri.
Shan magani sau da yawa yana farawa da kwamfutar hannu ɗaya. Ya danganta da sakamakon far, maganin zai iya bambanta. Matsakaicin adadin izinin allunan a kowace rana shine 6, saboda yana da haɗari a ɗauke su a matakin mafi girma. Ingantaccen tsarin magani da aka zaɓa ana ƙaddara shi da ƙimar glucose da aka cimma.
Yana da mahimmanci ga marasa lafiya su bi shawarar likita game da abinci mai gina jiki, hanyar gudanarwa da kuma yawan maganin. Tare da ciwon sukari mai lalacewa, matsananciyar yunwa, shan barasa, ƙarancin aikin hanta, da kowane bayyanar cututtuka na hypoxia, ya kamata a dauki allunan tare da taka tsantsan saboda haɗarin da ake samu na lactic acidosis. Wannan yanayin sakamako ne na tarawar metformin, sakamakon wanda aka gano lactate a cikin jini.
Yarda da kudade ya kunshi aikin tilas na gwaje-gwajen jini don halittar:
- Sau ɗaya a shekara yayin aikin koda na al'ada (a cikin marasa lafiya da ciwon sukari);
- fiye da sau 2 a shekara a cikin mutanen da ke dauke da HBV (haihuwar haihuwar hyrenplasia) ko kuma a cikin tsofaffi marasa lafiya.
Umarnin na musamman:
- amfani tare da taka tsantsan tare da diuretics;
- Kada ku ɗauki magani na kwana biyu kafin gwajin X-ray ɗin da aka tsara ko tiyata ta amfani da maganin sa maye, maye gurbinsa da insulin ko wasu magunguna;
- sake dawo da magani ne kawai bayan awanni 48 daga lokacin da duk wani aikin tiyata ya kuma kasance a karkashin yanayin yadda ake aiwatar da aikin koda da kodan;
- kar a sha barasa tare da magani domin a guji yawan zubar jini ko faruwar wasu halaye daban-daban dangane da asalin maye na giya;
- miyagun ƙwayoyi suna rage ragi na halayen psychomotor, wanda zai iya yin illa ga tuki.
Ciwon sukari guda biyu shine ɗaya daga cikin cututtukan da mai haƙuri yake da shi. A gaban sauran cututtukan, yana da muhimmanci a sha maganin tare da taka tsantsan.
Specialungiyar musamman ta marasa lafiya sune:
- masu ciki ko masu shayar da jarirai (an sanya maganin ne);
- marassa lafiya da ke fama da aikin hanta (an haramta amfani da maganin ne);
- mutane masu matsalar koda (tare da creatinine daga 135 mmol / l a cikin maza kuma sama da 100 mmol / l a cikin mata, an haramta maganin ƙwayar cuta).
Ba a ba da shawarar yin amfani da miyagun ƙwayoyi don amfani da marasa lafiya fiye da shekaru 60 ba, tun da lokacin da suke yin aiki na zahiri, zasu iya haɓaka lactic acidosis.
Side effects da yawan abin sama da ya kamata
Shan miyagun ƙwayoyi na iya haifar da halayen masu illa masu zuwa:
- dangane da tsarin narkewa - hare-hare na tashin zuciya da amai, asara ko cikakken asarar ci, matsewar tashin hankali;
- daga tsarin kewaya - leukopenia, kazalika da anemia da pancytopenia;
- dangane da tsarin juyayi, ciwon kai;
- itching, urticaria, erythema;
- hypoglycemia ko lactic acidosis;
- zuciya palpitations.
Tare da yawan wuce haddi na miyagun ƙwayoyi, kyautatawa mara haƙuri yana ƙaruwa, cututtukan jini na haɓaka. A wannan yanayin, dole ne ku ci carbohydrates. Ci gaban hawan jini na iya haifar da asarar iko da kai. A wannan yanayin, mai haƙuri ba shi da damar ci, saboda haka za a buƙaci glucose na cikin jiki da kulawa da likita.
Yin hulɗa tare da wasu magunguna da analogues
An inganta tasirin hypoglycemic na miyagun ƙwayoyi a ƙarƙashin rinjayar wakilai kamar:
- Abubuwan Coumarin;
- Salicylates;
- MAO masu hanawa;
- Abubuwan da ke faruwa na phenylbutazone;
- Sulfonamides;
- Miconazole;
- Feniramidol;
- Ethanol
Don rage tasirin amfani da miyagun ƙwayoyi ya shafa:
- Glucocorticoids;
- Thiazide diuretics;
- hana haihuwa (na baka);
- hormones don kula da glandar thyroid;
- Adrenaline.
Idan Glibomet saboda wasu dalilai bai dace ba, akwai da yawa na analogues ɗin, ana rarrabe cikin kayan haɗin kai da farashi.
Babban analogues:
- Karfe Galvus;
- Glimecomb;
- Avandaglim;
- Janumet;
- Avandamet;
- Harshen Combogliz.
Yana da mahimmanci a fahimci cewa likita kawai ya kamata ya yanke shawara game da maye gurbin Glibomet tare da wasu magunguna.
Bidiyo akan hanyoyi guda bakwai don rage sukarin jini a gida:
Ra'ayoyin masu haƙuri da farashin magunguna
Daga sake dubawar marasa lafiya, ana iya kammala da cewa ya kamata a sha maganin tare da taka tsantsan, tunda yana da illoli da yawa, hakanan ya zama dole a nemi kwararru kafin a sha maganin.
Na fara shan maganin kamar yadda likita ya umarta. A ranar farko ta jiyya, ta ji alamun sau biyu na maganin rashin ƙarfi, kodayake abincin ta bai canza ba. Ban iya zuwa wurin likita nan da nan ba, don haka sai na yanke shawarar kaina in sake yin gwaji kuma na koma shan magungunan da suka gabata.
Svetlana, shekara 33
Na yi matukar farin ciki da Glibomet. Tare da taimakonsa, ya yiwu ya daidaita matakin sukari. Bayan karanta umarnin, da farko ya ji tsoron babban jerin sakamako masu illa, amma ya yanke shawarar amincewa da likita. Sakamakon ya gamsar.
Egor, shekara 46
A bara na ɗauki waɗannan kwayoyin. Wannan magani bai dace da ni ba, saboda ɗanɗanar ƙarfe a bakina yana kasancewa koyaushe kuma wani lokacin sai na ji ƙyamar.
Nikita Alexandrovich, shekara 65
Kayan aiki yana rage sukari da kyau, amma yayin cin abincinsa ba za ku iya tsallake ko da abun ciye-ciye ba, ba kamar manyan abinci ba. Glybomet yana buƙatar abinci mai gina jiki na yau da kullun saboda babu hypoglycemia.
Irina, shekara 48
Kudin maganin yana kusan 350 rubles don allunan 40.
