A cikin hadaddun hanyoyin magance cututtukan da ke tattare da rikice-rikice a cikin tsarin wurare dabam dabam, ana nuna amfani da vasodilators, gami da Pentoxifylline.
Lokacin amfani da maganin, umarnin da aka haɗa ya kamata a kiyaye shi sosai.
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Ana ba da izinin shirye-shiryen Pentoxifylline bisa hukuma don amfani da maganin cututtukan trophic, gangrene, angiopathy kuma tare da karkacewa a cikin tsarin gani a cikin marasa lafiya da ciwon sukari.
Saki siffofin da abun da ke ciki
Magungunan an yi su ne a cikin nau'ikan allunan, dragees da kuma mafita wanda aka shirya don infusions na ciki (dropers), injections da gudanarwar intramuscular.
Ko da wane irin nau'in saki, dole ne kwayar ta ƙunshi babban sinadaran aiki - pentoxifylline sinadaran (a cikin Latin - Pentoxyphyllinum).
A wannan yanayin, sashi na sashi mai aiki na iya bambanta.
Kwayoyi
Allunan da ke ciki masu dauke da kwayoyin sunadarai sunada 100 MG na pentoxifylline.
Magungunan yana cikin rukunin vasodilators (vasodilators).
Magani
Maganin da aka yi amfani da allura ya ƙunshi 20 MG na kayan aiki mai aiki a cikin 1 ml. Ana sayar da maganin a cikin ampoules na 1, 2, 5 ml.
Jelly wake
Dragees (retard) sune capsules wadanda suke da membrane fim mai ruwan hoda. A cikin kwamfutar hannu 1 ya ƙunshi 400 MG na abu mai aiki.
Hanyar aikin
Magungunan yana cikin rukunin vasodilators (vasodilators).
Tasirin magungunan ƙwayar cuta yana nufin daidaita al'ada kewaya jini da haɓaka kaddarorin jini.
Wannan magani yana da sakamako mai zuwa akan jikin mai haƙuri:
- yana rage danko na jini, yana rage yiwuwar makarar jini;
- dilates tasoshin jini (a matsakaici), kawar da matsaloli tare da microcirculation jini;
- yana haɓaka jijiyoyin jijiyoyin jiki tare da iskar oxygen, hana haɓakar hypoxia (saboda haɓakar jijiyoyin bugun zuciya da jijiyoyin bugun zuciya);
- qara sautin diaphragm, tsokoki na numfashi;
- tasiri mai amfani kan ayyukan juyayi;
- Taimaka wajan kawar da jijiyar wuya da jin zafi a cikin ƙwayoyin maraƙin da ke da alaƙa da rikicewar jijiyoyin jiki a cikin gabobin.
A miyagun ƙwayoyi rage jini danko, da rage yiwuwar jini clots.
Pharmacokinetics
Abubuwan da ke aiki na miyagun ƙwayoyi suna haɗuwa sosai cikin jini daga narkewa kuma ana samun metabolized a hanta. Abubuwan da ke tattare da magani suna daga jikin mutum yayin rana ta hanjin kodan (tare da fitsari) da hanji (tare da jijiyoyi).
Abinda ya taimaka
Ana amfani da magani a cikin lura da waɗannan cututtukan masu zuwa:
- take hakkin jini a hannu da kafafu (Raunin Raynaud);
- lalacewar nama sakamakon lalacewar microcirculation na jini a cikin jijiyoyin jini da jijiyoyin jini (rauni na fata, rauni na postphlebotic syndrome, gangrene);
- raunin gani da ji da ke hade da karancin jini;
- ischemia na kwakwalwa;
- Cutar Buerger (thromboangiitis obliterans);
- karancin jini wanda ya haifar da karancin wadataccen jini ga sassan jikin haihuwa;
- atherosclerosis na cerebral;
- hauhawar jini;
- angiopathy a cikin marasa lafiya da ciwon sukari mellitus;
- cututtukan zuciya da na jijiyoyin jini;
- cincin dystonia;
- encephalopathy na daban-daban etiologies.
Hakanan ana amfani da kayan aiki a cikin maganin osteochondrosis azaman mai tallafawa vasodilator.
Contraindications
Jerin magungunan hana amfani da maganin sun hada da:
- cutar porphyrin;
- m rashin ƙarfi infarction;
- bashin jini;
- tsananin zubar jini.
Ba'a amfani da mafita don atherosclerosis na arteries na kwakwalwa da zuciya da tsananin tashin hankali.
Yin amfani da Pentoxifylline a cikin marasa lafiya tare da hypersensitivity ga bangaren aiki na miyagun ƙwayoyi, tsofaffi a cikin abun da ke ciki, ko wasu magunguna daga ƙungiyar xanthine an cire shi.
Tare da atherosclerosis na arteries na kwakwalwa da zuciya, kada kuyi amfani da magani a cikin hanyar magancewa.
Yadda ake ɗauka
Magungunan, ana samun su ta nau'ikan kwalliya da allunan, an yi shi ne don gudanar da maganin baka. Yi amfani da magani bayan abinci. Ba za ku iya tauna kwalliyar ba. Ya kamata a wanke su da ruwa kaɗan.
Likita ya ƙayyade ainihin yanayin maganin a kowane ɗayan mai haƙuri, la'akari da halayen jikinsa kuma ya dogara da bayanai daga hoton asibiti na cutar. Tsarin magunguna na yau da kullun shine 600 MG kowace rana (200 mg sau 3 a rana). Bayan makonni 1-2, lokacin da alamun rashin lafiyar ya zama ba a bayyana ba, ana rage adadin yau da kullun zuwa 300 MG (100 MG sau 3 a rana). Kada ku ɗauki fiye da adadin maganin da aka ba da shawarar a kowace rana (1200 mg).
Tsawon lokacin jiyya tare da pentoxifylline a cikin allunan shine makonni 4-12.
Ana iya gudanar da maganin za a iya sarrafa shi cikin intramuscularly, intravenously da intraarterially. Sashi yana ƙaddara da akayi daban-daban, yin la'akari da tsananin cututtukan jijiyoyin jiki. Umarnin don yin amfani da miyagun ƙwayoyi ya bayyana cewa kuna buƙatar amfani da maganin kamar haka:
- A cikin nau'ikan droppers - 0.1 g na miyagun ƙwayoyi wanda aka haɗu da 250-500 ml na ruwan gishiri ko 5% na glucose bayani. Wajibi ne a gudanar da maganin a hankali, cikin awanni 1.5-3.
- Injections (na cikin ciki) - a matakin farko na jiyya, an wajabta 0.1 g na miyagun ƙwayoyi (an dillance a cikin 20-50 ml na sodium chloride), to sai an ƙara yawan kashi zuwa 0.2-0.3 g (gauraye da 30-50 ml na sauran ƙarfi). Dole ne a gudanar da maganin a hankali (0.1 g na minti 10).
- Intramuscularly, ana gudanar da maganin a cikin kashi na 200-300 mg sau 2-3 a rana.
Tsarin magunguna na yau da kullun shine 600 MG kowace rana (200 mg sau 3 a rana).
Amfani da maganin zai iya haɗu tare da sarrafawa na baka na nau'in kwamfutar hannu na maganin.
Tare da ciwon sukari
Ana ba da izinin shirye-shiryen Pentoxifylline bisa hukuma don amfani da maganin cututtukan trophic, gangrene, angiopathy kuma tare da karkacewa a cikin tsarin gani a cikin marasa lafiya da ciwon sukari. Koyaya, zaku iya ɗaukar magani kawai kamar yadda likitan likita ya umarta, wanda ya saita sashi daban-daban kuma yana da tabbacin zai iya daidaita shi idan mai haƙuri ya ɗauki magungunan hana haihuwa. Magungunan kai na kai tare da pentoxifylline a cikin wannan halin ba a yarda da su ba, saboda zaɓin hanyar da aka zaɓa ba daidai ba na iya haifar da haɓaka halayen da ba a so (ciki har da hypoglycemic coma).
Pentoxifylline a cikin aikin gina jiki
Yin amfani da Pentoxifylline na iya zama da amfani ba wai kawai don magance cututtukan wurare dabam dabam ba, har ma a wasanni, tunda likitan yana da ikon ƙara haɓaka horo, haɓaka haƙuri, da haɓaka nasarar da ake so sakamakon sakamako mai amfani sakamakon jiki.
Pentoxifylline yana da ikon haɓaka tasiri na horo, ƙara haƙuri, ƙara hanzarta cimma nasarar da ake so.
An shawarci 'yan wasa da masu motsa jiki su dauki wannan maganin kamar haka:
- Wajibi ne a fara da karamin sashi - 200 MG 2 sau a rana. Sha kwayoyin magani bayan abinci.
- A cikin rashin sakamako masu illa da kuma haƙuri mai kyau na miyagun ƙwayoyi, zaku iya ƙara yawan adadin yau da kullun zuwa 1200 MG (400 MG sau 3 a rana).
- Don cimma sakamako mafi kyau, ana bada shawara don ɗaukar miyagun ƙwayoyi mintuna 30 kafin motsa jiki da 'yan sa'o'i bayan kammalawa.
- Tsawon lokacin amfani da miyagun ƙwayoyi shine makonni 3-4. Bayan hanya, kuna buƙatar ɗaukar hutu na watanni 2-3.
Side effects
Lokacin shan magani, abin da ya faru daga mummunan halayen daga gabobin ciki da tsarin mahimmanci ba zai yanke hukunci ba.
Gastrointestinal fili
A miyagun ƙwayoyi na iya haifar da kumburi hanta, tare da wahala a cikin ambaliya na yawan ƙwayar cuta, da haɓaka da cutar kumburi da ƙwaƙwalwar ƙwayar cuta, haɓakar motsin hanji, rage yawan ci, da kuma jin bushewa a cikin rami na baka. A lokuta da dama, ana lura da zubar jini na hanji.
Kayan aiki na iya haifar da kumburin hanta, tare da wahala a cikin zubarda yawan talakawa.
Hematopoietic gabobin
Wadannan halayen da ba daidai ba daga tsarin na wurare dabam dabam suna iya yiwuwa:
- raguwa a cikin matakan platelet a cikin jini;
- sauke cikin karfin jini;
- ciwon zuciya
- zuciya tashin hankali.
Tsarin juyayi na tsakiya
Damuwa, ciwon kai, farin ciki, da rashin isasshen barci na iya faruwa.
Marasa lafiya da ke shan maganin sau da yawa yakan zama abin haushi kuma yana fama da matsanancin damuwa.
Cutar Al'aura
Lokacin amfani da magani, halayen fata na fata (itching, urticaria) da kuma girgiza anaphylactic ana iya yiwuwa.
Sauran halayen
Wataƙila za a iya yin barna a cikin yanayin gashi, kusoshi, kumburi, jan launi na fata (“yakai” jini a fuska da kirji).
Lokacin amfani da magani, halayen ƙwayar fata da rawar jiki ana iya haɓaka.
Lationuntar tsinkayewar gani da ci gaban scotomas na ido ba a cire su.
Umarni na musamman
Ana gudanar da aikin Pentoxifylline tare da taka tsantsan a cikin mutanen da ke fama da cututtukan fata na ciki da duodenum, cututtukan da kodan da hanta, bugun zuciya, kuma suna iya zama hawan jini. Ga waɗannan nau'ikan marasa lafiya, daidaitaccen ma'aunin sashi da ingantaccen kulawar likita a duk lokacin da ake amfani da su ya zama dole.
Amfani da barasa
Likitocin sun bada shawarar sosai ga marassa lafiyar da ke shan magani dangane da Pentoxifylline na ban da shan giya kafin karshen magani.
An ba da shawarar cewa a cire giya kafin a gama magani da Pentoxifylline.
Ethyl barasa yana iya ɗaure wa kwayoyin ƙwayar kwayoyi, hana su ko haɓaka aikin abubuwan da ke aiki, wanda zai haifar da raguwar tasiri na miyagun ƙwayoyi ko haifar da rikice-rikice.
Tasiri kan ikon sarrafa abubuwan inji
Magungunan ba su da tasiri kai tsaye don fitar da abubuwa masu rikitarwa, ciki har da abubuwan hawa, duk da haka, idan wasu sakamako masu illa (rashin jin tsoro, damuwa na bacci, da sauransu) ya faru, hankalin mai haƙuri zai iya lalacewa. Wannan na iya rage ingancin tuki da sauran abubuwan hawa.
Yayin ciki da lactation
Lokacin shayarwa da lokacin daukar ciki, an haramta yin amfani da miyagun ƙwayoyi. Idan mace mai jinyar ba za ta iya shan maganin ba, to ya kamata ta daina shan nono kafin karshen maganin.
Abinda aka wajabta wa yara
Ba a yi nazarin tasiri da amincin miyagun ƙwayoyi ba a cikin ƙuruciya, don haka masana'antun Pentoxifylline ba su ba da shawarar rubuta wannan magani ga marasa lafiya da ke ƙasa da shekara 18.
Ba a ba da shawarar Pentoxifylline ga marasa lafiya da ke ƙasa da shekara 18 ba.
Koyaya, a aikace, idan ya zama tilas, likitoci zasu iya ba da wannan magani ga yaro wanda ya wuce shekaru 12. Mafi yawan lokuta wannan shine saboda raunin jijiyoyin jini da kuma rashin amfanin yin amfani da wani magani.
Sashi a cikin tsufa
A cikin tsufa, kawar da miyagun ƙwayoyi yana raguwa, saboda haka yana da shawarar yin amfani da rage yawan ƙwayoyi.
Yawan damuwa
Tare da tsawanta amfani da babban allurai na miyagun ƙwayoyi, alamomin masu zuwa sama na faruwa na iya faruwa:
- tashin zuciya, vomiting na "filayen kofi" (yana nuna ci gaban zubar jini);
- Dizziness
- rauni
- katsewa.
A cikin lokuta masu tsauraran magungunan ƙwayar cutar ƙwayar cuta, suma, damuwa na numfashi, anaphylaxis.
A cikin mafi yawan lokuta masu rauni, fitsari, raunin numfashi, anaphylaxis ana lura.
Yin hulɗa tare da wasu kwayoyi
Kwayoyi na iya haɓaka sakamakon magungunan masu zuwa:
- maganin cututtukan jini;
- thrombolytics;
- kwayoyi waɗanda ke rage karfin jini;
- maganin rigakafi
- insulin-dauke da kwayar cutar hypoglycemic;
- valproic acid-tushen shirye-shirye.
Yin amfani da Pentoxifylline na lokaci guda da magunguna dauke da cimetidine yana kara haɗarin sakamako masu illa. Shirye-shirye dangane da ketorolac da mexicam ba su dace da Pentoxifylline ba, saboda lokacin hulɗa tare da magani, suna ƙaruwa da damar haɓakar jinni na cikin gida.
Zaka iya siyan siklar ne kawai idan likitan likitan ka ya tsara ka.
Ba'a ba da shawarar a haɗa amfani da miyagun ƙwayoyi tare da amfani da wasu magungunan xanthines ba, tunda wannan na iya haifar da wuce gona da iri na juyayi.
Analogs
A cikin lura da cututtukan cututtukan da ke haifar da rikicewar Sistem, ana amfani da analogues na Pentoxifylline masu zuwa:
- Cavinton;
- Trental;
- Pentoxifylline-NAS;
- Piracetam
- Pentilin;
- Mexidol;
- Fluxital;
- Latren;
- nicotinic acid.
Don sanin wanne daga cikin waɗannan magunguna ne yafi dacewa don cuta ta musamman, ya kamata ka nemi likitanka.
Mai masana'anta
Magungunan da aka samar a Rasha ana samar da su ne ta kamfanonin magunguna Organka (Novokuznetsk) da Akrikhin (Moscow). Irin waɗannan magunguna sune kamfanonin Czech (Zentiva) da kamfanonin Isra'ila (Teva) suke yi.
Magunguna kan bar sharuɗan
Zaka iya siyan siklar ne kawai idan likitan likitan ka ya tsara ka.
Farashin Pentoxifylline
Magunguna da aka samar a Rasha suna da ƙananan farashi - daga 40 zuwa 150 rubles. Magungunan da aka shigo da pentoxifylline sun ninka sau biyu.
Yanayin ajiya
Don adanawa a cikin wurin da aka kiyaye shi daga yara, a zafin jiki na sama da + 25 ° C.
Magunguna da aka samar a Rasha suna da ƙananan farashi - daga 40 zuwa 150 rubles.
Pentoxifylline
Ana iya amfani da kayan aiki a cikin shekaru 3 daga ranar samarwa.
Sanarwa Pentoxifylline
Yawancin likitoci da marasa lafiya suna ba da amsa ga ingancin amfani da Pentoxifylline.
Likitoci
E. G. Polyakov, neurosurgeon, Krasnoyarsk
A miyagun ƙwayoyi yana da tabbatacce sakamako a cikin wasu cuta na tsakiya da kuma na gefe wurare dabam dabam. Kayan aiki yana da inganci mai mahimmanci da ƙarancin farashi, saboda haka ya zama akwai duka nau'ikan marasa lafiya. Rashin daidaituwa na miyagun ƙwayoyi ya haɗa da sakamako mai rauni a cikin angiopathies.
Marasa lafiya
Lily, shekara 31, Astrakhan
A da, sau da yawa na sha fama da hare-hare na dystonia na tsire-tsire-tsire-tsire-tsire-tsire-tsire, wanda ya rinjayi rayuwata. Yanzu ana bi da ni tare da Pentoxifylline. Tare da hari na gaba, na fara ɗaukar wannan maganin a hanya (a cikin kwanaki 10). Taimako yana faruwa a cikin kwanakin farko na jiyya, kuma bayan kwanaki 10 duk alamun ta tafi gaba ɗaya. An ba da kulawa ta musamman ga farashin maganin: yana da ƙasa sosai wanda a farkon yana ma yana da ban tsoro. Amma ƙimar Pentoxifylline ta Rasha ba ta da mummunar ƙarancin analogues na ƙasashen waje, wanda ya biya 2, ko ma sau uku mafi tsada.
Igor, ɗan shekara 29, Volgograd
Don inganta microcirculation na jini a cikin kodan, dole ne a dauki masu bugun jini.An ba da Curantil a baya, amma kansa ya fara ciwo mai yawa, don haka dole ne in canza zuwa Trental. Waɗannan kwayoyi ne masu kyau, amma masu tsada sosai, don haka na yanke shawarar maye gurbinsu da Pentoxifylline da aka yi da Rasha. Ban lura da wani banbanci ba (ban da farashin). Suna kuma aiki, ba sa haifar da illa, suna yin aikinsu daidai.
