Actovegin - magani ne wanda ke taimaka wa kwantar da hankulan tafiyar matakai a cikin kyallen da jijiyoyin jini, yana karfafa tsarin farfadowa.
Sunan kasa da kasa mai zaman kansa
Ba ya
Sunan kasuwanci shine Actovegin®. A cikin Latin - Actovegin.
Ampoules tare da ruwa mai tsabta ko ruwan rawaya mai haske don allura.
ATX
B06AB (Sauran kayayyakin jini)
Saki siffofin da abun da ke ciki
Ampoules tare da ruwa mai tsabta ko ruwan rawaya mai haske don allura.
Abunda yake aiki: hemoderivative mai narkewa, 40 MG / ml.
Ya haifar da dialysis, membrane rabuwa da kuma yanki na jini barbashi na matasa dabbobi, ciyar da madara na musamman.
Comparin bangaren: ruwa don allura.
Ana iya samar dashi ta kamfanonin magunguna Takeda Austria GmbH (Austria) ko Takeda Pharmaceuticals LLC (RF). Sanya cikin 2 ml, 5 ko 10 ml a cikin ampoules gilashi mara launi na 5 inji mai kwakwalwa. a cikin kwane-kwane na kwanon da aka yi da filastik. Katako mai kunshe 1, 2 ko 5 a cikin kwali.
Magungunan yana cikin rukunin magungunan maye gurbinsu.
A kowane kwali na kwali akwai kwalin kwali tare da rubutun holographic da kuma lura da budewar farko.
Aikin magunguna
Ta kasance ta ƙungiyar antihypoxants. A lokaci guda yana da nau'ikan sakamako 3:
- neuroprotective (yana hana mutuwar sel kwakwalwa - neurons - saboda mummunan tasirin ayyukan ciki da ake so ko tasirin waje);
- metabolic (yana haɓaka aikin adenosine triphosphate (ATP) kuma yana ƙaruwa da ƙarfin ƙwayoyin sel);
- microcirculatory (ingantaccen jigilar ruwa mai gudana a cikin kyallen da tasoshin jikin).
Yana taimakawa haɓaka sihirin da aiki da iskar oxygen da glucose.
Yana kawo rikitarwa akan ƙirƙirar hanyoyin apoptotic wanda tsokanar beta-amyloid ta haifar (Aβ25-35). Yana canza motsi na wakilin nukiliya kappa B (NF-kB), wanda shine babban maɓallin motsa jiki yayin aiwatar da kumburi a cikin tsakiya da jijiyoyin jijiyoyin jiki da kuma apoptosis.
Yana da tasiri mai tasiri akan microcirculation da gudanawar jini a cikin capillaries, rage yankin pericapillary da matsa lamba na diastolic. An tabbatar da cewa an lura da tasiri na maganin bayan mintuna 30, kuma mafi girman tasirin shine 3 hours bayan gudanarwa.
Actovegin yana da tasiri mai tasiri akan microcirculation da gudanawar jini a cikin abubuwan capillaries.
Pharmacokinetics
Tunda miyagun ƙwayoyi suna da abubuwan haɓaka na jiki wanda ya kasance a jikin mutum, kayan aikin magungunansa bisa ga sigogi na dakin gwaje-gwaje ba za a yi nazarin su ba.
Abin da aka wajabta
Actovegin 40 an haɗo shi cikin hadaddun hanyoyin magani:
- fahimtar rikice-rikice na etiologies daban-daban;
- naƙasasshe na jijiyoyin jiki da haɗarin cerebrovascular;
- na gefe angiopathy;
- mai ciwon sukari mai cutar kansa;
- farfadowa na nama (rauni, tiyata, raunuka na ƙananan sassan, da sauransu);
- Sakamakon maganin radiation.
Bugu da kari, tare da wannan nau'in sashi, ana magance cututtukan gastro na gastro, cututtukan mahaifa na ciki da duodenum.
Contraindications
Ba'a ba da shawarar don yawan wuce gona da iri ga abubuwan da ke cikin miyagun ƙwayoyi ba, lalata ƙwaƙwalwar zuciya, edema a cikin tsarin bronchopulmonary, oliguria, anuria da tafiyar matakai a cikin jiki.
Tare da kulawa
A gaban hyperchloremia da hypernatremia, a cikin yara.
Yadda ake ɗaukar Actovegin 40
Tsawon lokaci, allurai da tsarin kulawa an ƙayyade su ne bisa halayen tsarin ilimin hanyoyin. An ƙaddara akayi daban-daban. An wajabta shi cikin ciki, cikin zazzagewa da intramuscularly.
A cikin lura da raunuka na jijiyoyin jiki da na jijiyoyin bugun kwakwalwa, a farkon matakan jiyya, 10-20 ml na iv ko iv ana allurar yau da kullun. To, bisa ga tsarin kulawa, 5 ml iv ko IM tare da jinkiri jinkiri.
A cikin ischemic bugun jini a cikin babban mataki, ana ba da magunguna.
A cikin rauni na ischemic a cikin babban mataki, ana yin infusions. Don wannan, an ƙara magani (10-50 ml) zuwa 200-300 ml na isotonic abun da ke ciki (5% glucose ko sodium chloride bayani). Bayan wannan, an canza tsarin magani don ɗaukar nau'in kwamfutar hannu na maganin.
Don lura da yanayin da ya haifar da rikicewar jijiyoyin kwakwalwa, wannan magani an wajabta iv ko iv (20-30 ml na maganin yana haɗuwa da 200 ml na isotonic abun da ke ciki).
Don cire alamun cututtukan ciwon sukari, allurar 50 na iv an allurar. Sannan tasirin warkewa ya canza zuwa amfani da Actovegin a cikin allunan.
Tare da gudanarwar / m, ana amfani da 5 ml. Shiga da hankali.
Shan maganin don ciwon sukari
Yana nufin magunguna waɗanda ke taimakawa ga daidaituwa na metabolism. Saboda haka, wajibi ne a cikin hadaddun jiyya na ciwon sukari.
Ana buƙatar magani a cikin hadadden magani na ciwon sukari.
Side effects
An yarda da kyau. A cikin halayen da ba a sani ba, illa na iya faruwa.
Daga tsarin musculoskeletal
Myalgia (da wuya).
Daga tsarin rigakafi
Allergic halayen a cikin hanyar bayyanar asibiti na zazzabi magani ko zazzabi anaphylactic.
A ɓangaren fata
Kumburi, rashes, ko jan launi.
Cutar Al'aura
Dole ne a sanar da kasancewar yanayin shigarwar abin da zai haifar da rashin lafiyan bayyanuwa ga likita.
Sakamakon sakamako na miyagun ƙwayoyi na iya zama rashin lafiyan ƙwayar cuta.
Umarni na musamman
Saboda haɗarin tashin gwajin cutar anaphylactic yayin amfani na farko, ya kamata a yi gwajin tashin hankali na wannan maganin kafin gudanarwa.
A cikin bature daban-daban, miyagun ƙwayoyi na iya samun ƙarfin launi daban-daban. Amma wannan ba ya shafar haƙuri da miyagun ƙwayoyi da ayyukanta.
Ampoules da aka buda. Ya kamata a yi amfani dasu nan da nan.
Amfani da barasa
Lokacin da shan giya baya rasa kayan aikin magani.
Tasiri kan ikon sarrafa abubuwan inji
Babu bayanai.
Lokacin da shan giya baya rasa kayan aikin magani.
Yi amfani da lokacin daukar ciki da lactation
Ba a lura da mummunan sakamako game da yanayin mahaifiyar ko tayi ba.
Wakilin Actovegin 40
An sanya shi ga jarirai tare da alamun hypoxia. Bugu da kari, an bayar da maganin ne ga yara masu haihuwa da kuma raunuka masu kwakwalwa.
Yi amfani da tsufa
Ana amfani dashi a cikin jiyya da rigakafin cututtukan cututtukan zuciya da ischemic na gabobin da kyallen takarda a cikin marasa lafiyar da ke da shekaru.
Yawan damuwa
Babu wasu lokuta da suka shafi yawan zubar da ruwan Actovegin.
Ana amfani dashi a cikin jiyya da rigakafin cututtukan cututtukan zuciya da ischemic na gabobin da kyallen takarda a cikin marasa lafiyar da ke da shekaru.
Akwai yuwuwar samun bayyanuwar bayyanar cututtuka.
Yin hulɗa tare da wasu kwayoyi
Ba a sami sakamako mai illa daga ma'amala da miyagun ƙwayoyi ba.
Ya dace da nau'ikan magungunan da ake amfani da su a cikin hadaddun hanyoyin magance cututtukan ischemic (alal misali, tare da Mildronate).
Bugu da ƙari, ana amfani dashi sosai cikin tsarin haɗin gwiwa tare da kwayoyi waɗanda aka yi amfani da su don kawar da ƙarancin ƙwaƙwalwar hanji da ƙarancin ƙwayar cuta, a cikin maganin thrombosis (alal misali, tare da Curantyl).
Haɗuwa yana buƙatar taka tsantsan
Haɗuwa tare da masu hana ACE (Enalapril, Lisinopril, Captopril, da dai sauransu), tare da shirye-shiryen potassium, suna buƙatar taka tsantsan.
Analogs
Madadin Actovegin sune:
- Vero-Trimetazidine;
- Curantyl-25;
- Cortexin;
- Cerebrolysin, da sauransu.
Curantil-25 sigar analog ce ta Actovegin.
Magunguna kan bar sharuɗan
Da takardar sayan magani.
Zan iya siye ba tare da takardar sayan magani ba
Yawancin kantin magani na kan layi suna shirye su sayar ba tare da takardar sayan magani ba.
Farashin Actovegin 40
Matsakaicin farashin ya dogara da ƙarar ampoules da lambar su a cikin kunshin. Don haka, alal misali, a cikin Rasha, farashin Actovegin (injection don 40 mg / ml ampoules na 5 ml 5 inji mai kwakwalwa.) Bambanci daga 580 zuwa 700 rubles.
A cikin Ukraine, nau'in kunshin mai kama da kusan 310-370 UAH.
Matsakaicin farashin maganin yana dogara da ƙarar ampoules da lambar su a cikin kunshin.
Yanayin ajiya na miyagun ƙwayoyi
A wurin da aka kiyaye shi daga zafin rana a zazzabi har zuwa 25 ° C. Boye daga yara.
Ranar karewa
Shekaru 3 daga ranar samarwa.
Mai masana'anta
Nycomed Austria GmbH, Austria.
Mai fakiti / mai ba da izinin kula da inganci: Takeda Pharmaceuticals LLC (Russia).
Nazarin likitoci da marasa lafiya akan Actovegin 40
Ra'ayoyin likitoci da marasa lafiya game da amfani, tasiri da aminci sun bambanta.
Vasilieva E.V., likitan ƙwayar cuta, Krasnodar
Actovegin bashi da illa ko kaɗan sannan kuma ana haƙuri da kyau. Ana iya amfani dashi duka a cikin maganin monotherapy kuma a cikin magunguna masu rikitarwa. Sanya shi don cututtuka na tsarin jijiyoyin jiki da kasawa na rayuwa. Ina bayar da shawarar ga yawancin marasa lafiya na.
Marina, yar shekara 24, Kursk
Sun ba da allura da digon ruwa yayin daukar ciki don a tabbatar da yaduwar jini a cikin mahaifa. Babu sakamako mai illa. Bayan jiyya, zubar jini ya koma al'ada, kuma gajiya da farin ciki sun ɓace tare da rashin lafiyar. Ina ba da shawara ga duk mata masu juna biyu.
Nefedov I.B., shekara 47, Oryol
Duk da cewa FDA ta haramtawa wannan magani (Ma'aikatar Lafiya da Ma'aikatar Bil Adama ta Amurka), ana amfani dashi sosai a Rasha da kuma kasashen CIS. Kasashen waje. Ban amince da kwayoyi ba, umarnin don hakan ya nuna cewa ba shi yiwuwa a kimanta kaddarorin magungunan ta.
Afanasyev P.F. likitan duban dan tayi, St. Petersburg
Kyakkyawan magungunan rigakafi tare da adana sakamako na warkewa har tsawon watanni 3-6. Ana amfani da wannan kayan aiki a asibiti a cikin Cibiyar Bincike. Ankylosing spondylitis don kawar da alamun cututtukan cerebrovascular da encephalopathy diski, sakamakon bugun jini da raunin kwakwalwa. Taimakawa don kawar da ciwon kai, migraines, jin damuwa, inganta ayyukan tunani, da dai sauransu.
